Premetastatic Niches

Tumor Microenvironment

Volumn , Issue , 2010, Pages 161-182

  Bennewith, Kevin L ^a,c   Erler, Janine T ^b,c   Giaccia, Amato J ^c  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BMDC accumulation and premetastatic niche formation in cancer patients; BMDC heterogeneity in premetastatic niches; Cancer related deaths attributed to metastatic spread of cancer; ECM connecting cells in tissues and assisting cell migration during wound healing; Metastasis, inefficient, multistep process determinants of 'successful' metastatic growth in a given organ, poorly understood; Premetastatic niche, new concept emerging in metastasis field; Premetastatic niches, localized microenvironments forming in metastatic target organs; Primary tumor microenvironment, influencing microenvironment within distant metastatic target organs; S100A8 and S100A9 secreted, inflammatory related proteins chemoattractants for monocytes and neutrophils; Therapeutic strategies therapeutically targeting premetastatic niches

Indexed keywords

EID: 84886015040     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470669891.ch8     Document Type: Chapter

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