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1
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33750328808
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The relationship between rhinosinusitis and asthma sinusitis
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This is a recent review that discusses the different classifications of chronic sinusitis and the role of mediators in the inflammatory process of the upper airway
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Steinke JW. The relationship between rhinosinusitis and asthma sinusitis. Curr Allergy Asthma Rep 2006; 6:495-501. This is a recent review that discusses the different classifications of chronic sinusitis and the role of mediators in the inflammatory process of the upper airway.
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Curr Allergy Asthma Rep
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, pp. 495-501
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Steinke, J.W.1
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2
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34247279632
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Asthma and the unified airway
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This paper describes the current understanding of the upper and lower airway with the emphasis on similarities of tissue and physiology at both sites
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Krouse JH, Brown RW, Fineman SM, et al. Asthma and the unified airway. Otolaryngol Head Neck Surg 2007; 136:S75-S106. This paper describes the current understanding of the upper and lower airway with the emphasis on similarities of tissue and physiology at both sites.
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Otolaryngol Head Neck Surg
, vol.136
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Krouse, J.H.1
Brown, R.W.2
Fineman, S.M.3
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4
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0032970520
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Comparison between nasal and bronchial inflammation in asthmatic and control subjects
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Chanez P, Vignola AM, Vic P, et al. Comparison between nasal and bronchial inflammation in asthmatic and control subjects. Am J Respir Crit Care Med 1999; 159:588-595.
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Am J Respir Crit Care Med
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Chanez, P.1
Vignola, A.M.2
Vic, P.3
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5
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33846199233
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Hypoxia-inducible factors: Central regulators of the tumor phenotype
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This paper demonstrates, using tumor models, how factors are regulated when exposed to a hypoxic environment
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Gordan JD, Simon MC. Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr Opin Genet Dev 2007; 17:71-77. This paper demonstrates, using tumor models, how factors are regulated when exposed to a hypoxic environment.
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Curr Opin Genet Dev
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, pp. 71-77
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Gordan, J.D.1
Simon, M.C.2
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6
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0033587146
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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
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Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999; 399:271-275.
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Nature
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Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
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7
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38049158047
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Histologic examination reveals distinct disease subsets of chronic sinusitis
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Early SB, Han J, Borish L, et al. Histologic examination reveals distinct disease subsets of chronic sinusitis. J Allergy Clin Immunol 2007; 119:S243.
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J Allergy Clin Immunol
, vol.119
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Early, S.B.1
Han, J.2
Borish, L.3
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8
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0030031274
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Experimentally induced polyps in the sinus mucosa: A structural analysis of the initial stages
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Norlander T, Westrin KM, Fukami M, et al. Experimentally induced polyps in the sinus mucosa: a structural analysis of the initial stages. Laryngoscope 1996; 106:196-203.
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Laryngoscope
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Norlander, T.1
Westrin, K.M.2
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9
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0031593532
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Comparative assessment of cell proliferation and accumulation of extracellular matrix in nasal polyps
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Nakagawa T, Yamane H, Nakai Y, et al. Comparative assessment of cell proliferation and accumulation of extracellular matrix in nasal polyps. Acta Otolaryngol 1998; 538:205-208.
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Acta Otolaryngol
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Nakagawa, T.1
Yamane, H.2
Nakai, Y.3
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10
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0343923408
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Myofibroblast accumulation induced by transforming growth factor-β is involved in the pathogenesis of nasal polyps
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Wang QP, Escudier E, Roudot-Thoraval F, et al. Myofibroblast accumulation induced by transforming growth factor-β is involved in the pathogenesis of nasal polyps. Laryngoscope 1997; 107:926-931.
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Laryngoscope
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Wang, Q.P.1
Escudier, E.2
Roudot-Thoraval, F.3
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11
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0742324996
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Characterization of interleukin-4 stimulated nasal polyp fibroblasts
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Steinke JW, Crouse CD, Bradley D, et al. Characterization of interleukin-4 stimulated nasal polyp fibroblasts. Am J Respir Cell Mol Biol 2004; 30:212-219.
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(2004)
Am J Respir Cell Mol Biol
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Steinke, J.W.1
Crouse, C.D.2
Bradley, D.3
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12
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33745630846
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Mediator feedback loops: Difficulties in treating chronic hyperplastic eosinophilic sinusitis/nasal polyposis
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Steinke JW. Mediator feedback loops: difficulties in treating chronic hyperplastic eosinophilic sinusitis/nasal polyposis. Recent Res Devel Allergy and Clin Immunol 2004; 5:15-25.
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(2004)
Recent Res Devel Allergy and Clin Immunol
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Steinke, J.W.1
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14
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20544473038
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Chronic hyperplastic eosiniphilic sinusistis as a predictor of aspirin-exacerbated respiratory disease
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Mascia K, Borish L, Patrie J, et al. Chronic hyperplastic eosiniphilic sinusistis as a predictor of aspirin-exacerbated respiratory disease. Ann Allergy Asthma Immunol 2005; 94:652-657.
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(2005)
Ann Allergy Asthma Immunol
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Mascia, K.1
Borish, L.2
Patrie, J.3
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15
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38049165132
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Little SC, Early SB, Woodard CR, et al. Dual action of TGF-β1 on nasal-polyp derived fibroblasts. Laryngoscope 2007 [in press] This paper describes how fibroblasts from nasal polyps are stimulated by TGF-β1 to produce profibrotic and proinflammatory factors that are involved in tissue remodeling.
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Little SC, Early SB, Woodard CR, et al. Dual action of TGF-β1 on nasal-polyp derived fibroblasts. Laryngoscope 2007 [in press] This paper describes how fibroblasts from nasal polyps are stimulated by TGF-β1 to produce profibrotic and proinflammatory factors that are involved in tissue remodeling.
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16
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85047693849
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Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
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Flood-Page P, Menzies-Gow A, Phipps S, et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest 2003; 112:1029-1036.
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J Clin Invest
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Flood-Page, P.1
Menzies-Gow, A.2
Phipps, S.3
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17
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85047693288
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Inhibition of airway remodeling in IL-5-deficient mice
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Cho JY, Miller M, Baek KJ, et al. Inhibition of airway remodeling in IL-5-deficient mice. J Clin Invest 2004; 113:551-560.
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(2004)
J Clin Invest
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Cho, J.Y.1
Miller, M.2
Baek, K.J.3
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18
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0038627930
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Hypoxia in paranasal sinuses of patients with chronic sinusitis with or without complication of nasal allergy
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Matsune S, Kono M, Sun D, et al. Hypoxia in paranasal sinuses of patients with chronic sinusitis with or without complication of nasal allergy. Acta Otolaryngol 2003; 123:519-523.
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(2003)
Acta Otolaryngol
, vol.123
, pp. 519-523
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Matsune, S.1
Kono, M.2
Sun, D.3
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19
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0028095127
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Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin
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Goldberg MA, Schneider TJ. Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J Biol Chem 1994; 269:4355-4359.
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Goldberg, M.A.1
Schneider, T.J.2
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20
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0345491599
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Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation
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Hu CJ, Wang LY, Chodosh LA, et al. Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation. Mol Cell Biol 2003; 23:9361-9374.
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Mol Cell Biol
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Hu, C.J.1
Wang, L.Y.2
Chodosh, L.A.3
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22
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12344302527
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Hypoxia, leukocytes, and the pulmonary circulation
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Stenmark KR, Davie NJ, Reeves JT, et al. Hypoxia, leukocytes, and the pulmonary circulation. J Appl Physiol 2005; 98:715-721.
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(2005)
J Appl Physiol
, vol.98
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Stenmark, K.R.1
Davie, N.J.2
Reeves, J.T.3
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23
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33947134561
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Hypoxia stimulates inflammatory and fibrotic responses from nasal-polyp derived fibroblasts
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This paper demonstrates that hypoxic exposure of nasal polyp fibroblasts increases profibrotic and pro-inflammatory factors
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Early SB, Hise K, Han JK, et al. Hypoxia stimulates inflammatory and fibrotic responses from nasal-polyp derived fibroblasts. Laryngoscope 2007; 117:511-515. This paper demonstrates that hypoxic exposure of nasal polyp fibroblasts increases profibrotic and pro-inflammatory factors.
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(2007)
Laryngoscope
, vol.117
, pp. 511-515
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Early, S.B.1
Hise, K.2
Han, J.K.3
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24
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0141987850
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Hypoxia modulates the effects of transforming growth factor-beta isoforms on matrix formation by primary human lung fibroblasts
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Papakonstantinou E, Aletras AJ, Roth M, et al. Hypoxia modulates the effects of transforming growth factor-beta isoforms on matrix formation by primary human lung fibroblasts. Cytokine 2003; 24:24-35.
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(2003)
Cytokine
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Papakonstantinou, E.1
Aletras, A.J.2
Roth, M.3
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25
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33646381148
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Chen YF, Feng JA, Li P, et al. Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling. J Appl Physiol 2006; 100:564-571. This paper used a mouse model to show the involvement of TGF-β1 in hypoxia-induced remodeling of the lung.
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Chen YF, Feng JA, Li P, et al. Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling. J Appl Physiol 2006; 100:564-571. This paper used a mouse model to show the involvement of TGF-β1 in hypoxia-induced remodeling of the lung.
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26
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20144373102
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Collagenase expression and activity is modulated by the interaction of collagen types, hypoxia, and nutrition in human lung cells
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Leufgen H, Bihl MP, Rudiger JJ, et al. Collagenase expression and activity is modulated by the interaction of collagen types, hypoxia, and nutrition in human lung cells. J Cell Physiol 2005; 204:146-154.
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(2005)
J Cell Physiol
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Leufgen, H.1
Bihl, M.P.2
Rudiger, J.J.3
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27
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33847361673
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Cell type-specific effect of hypoxia and platelet-derived growth factor-BB on extracellular matrix turnover and its consequences for lung remodeling
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Karakiulakis G, Papakonstantinou E, Aletras AJ, et al. Cell type-specific effect of hypoxia and platelet-derived growth factor-BB on extracellular matrix turnover and its consequences for lung remodeling. J Biol Chem 2007; 282:908-915.
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J Biol Chem
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Karakiulakis, G.1
Papakonstantinou, E.2
Aletras, A.J.3
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28
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23044447969
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TNF-alpha and endotoxin increase hypoxia-induced VEGF production by cultured human nasal fibroblasts in synergistic fashion
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Sun D, Matsune S, Ohori J, et al. TNF-alpha and endotoxin increase hypoxia-induced VEGF production by cultured human nasal fibroblasts in synergistic fashion. Auris Nasus Larynx 2005; 32:243-249.
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Auris Nasus Larynx
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Sun, D.1
Matsune, S.2
Ohori, J.3
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29
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0035573889
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Leukocyte-endothelial interactions in enviromental hypoxia
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Gonzalez NC, Wood JG. Leukocyte-endothelial interactions in enviromental hypoxia. Adv Exp Med Biol 2001; 502:39-60.
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Adv Exp Med Biol
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Gonzalez, N.C.1
Wood, J.G.2
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33744813253
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Altex, Using in-vitro cultured epithelial cells, this group demonstrated that hypoxia induction increased chemokine expression
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Pahl A, Szelenyi S, Brune K. Hypoxia induced chemokine expression in nasal epithelial cells: development of an in vitro model for chronic rhinosinusitis. Altex 2006; 23:59-63. Using in-vitro cultured epithelial cells, this group demonstrated that hypoxia induction increased chemokine expression.
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(2006)
Hypoxia induced chemokine expression in nasal epithelial cells: Development of an in vitro model for chronic rhinosinusitis
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, pp. 59-63
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Pahl, A.1
Szelenyi, S.2
Brune, K.3
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31
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Local tissue hypoxia and formation of nasal polyps
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Shu J, Zhen D, Dongdong Z, et al. Local tissue hypoxia and formation of nasal polyps. Chin Med J 2003; 116:243-247.
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Chin Med J
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Shu, J.1
Zhen, D.2
Dongdong, Z.3
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32
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34147147532
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Hypoxia increases the motility of lung adenocarcinoma cell line A549 via activation of the epidermal growth factor receptor pathway
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This report demonstrates the importance of the epidermal growth factor signaling pathway in response to hypoxic stimulation
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Wang T, Niki T, Goto A, et al. Hypoxia increases the motility of lung adenocarcinoma cell line A549 via activation of the epidermal growth factor receptor pathway. Cancer Sci 2007; 98:506-511.] This report demonstrates the importance of the epidermal growth factor signaling pathway in response to hypoxic stimulation.
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Cancer Sci
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Wang, T.1
Niki, T.2
Goto, A.3
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33
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Biochemical and morphological changes in endothelial cells in response to hypoxic interstitial edema
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Botto L, Beretta E, Daffara R, et al. Biochemical and morphological changes in endothelial cells in response to hypoxic interstitial edema. Respir Res 2006; 7:7.
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Respir Res
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Botto, L.1
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Irgoyen M, Anso' E, Martinez E, et al. Hypoxia alters the adhesive properties of lymphatic endothelial cells. A transcriptional and functional study. Biochim Biophys Acta 2007; 1773:880-890. This paper demonstrates that endothelial cells, in response to hypoxia, are able to increase expression of adhesion molecules, which recruits inflammatory cells to the sites of hypoxic stimulation.
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Irgoyen M, Anso' E, Martinez E, et al. Hypoxia alters the adhesive properties of lymphatic endothelial cells. A transcriptional and functional study. Biochim Biophys Acta 2007; 1773:880-890. This paper demonstrates that endothelial cells, in response to hypoxia, are able to increase expression of adhesion molecules, which recruits inflammatory cells to the sites of hypoxic stimulation.
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Stenmark KR, Fagan KA, Frid MG. Hypoxia-induced pulmonary vascular remodeling cellular and molecular mechanisms. Circ Res 2006; 99:675-691.
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Stenmark KR, Fagan KA, Frid MG. Hypoxia-induced pulmonary vascular remodeling cellular and molecular mechanisms. Circ Res 2006; 99:675-691.
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34548257911
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Clinical practice guideline on adult sinusitis
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This is an up-to-date review on the current management of chronic sinusitis
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Rosenfeld RM. Clinical practice guideline on adult sinusitis. Otolaryngol Head Neck Surg 2007; 137:365-377. This is an up-to-date review on the current management of chronic sinusitis.
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Otolaryngol Head Neck Surg
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Rosenfeld, R.M.1
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The effects of glucocorticoids on human eosinophils
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Schleimer RP, Bochner BS. The effects of glucocorticoids on human eosinophils. J Allergy Clin Immunol 1994; 94:1202-1213.
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