Hypoxia, Anerobic Metabolism, and Interstitial Hypertension

Tumor Microenvironment

Volumn , Issue , 2010, Pages 183-205

  Milosevic, Michael F ^a  

^a PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Anerobic metabolism and extracellular acidosis; Biologic behavior of cancer cells by intrinsic characteristics of cells and local microenvironment in which they exist; High interstitial fluid pressure (IFP) and reduced convection; Hypoxia, anerobic metabolism and interstitial hypertension; Hypoxia, developing in tumors when metabolic demand for oxygen exceeds availability; Link between tumor hypoxia and survival in cervix cancer patients and treatment with radiotherapy; Oxygen consumption by cancer cells determinants of tumor hypoxia; Spatial distribution of oxygen, not stable in tumors driven by periodic microregional fluctuations, and acute or cycling hypoxia; Techniques for measuring hypoxia in tumors; Tumor microenvironment spatial and temporal heterogeneity

Indexed keywords

EID: 84886000044     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470669891.ch9     Document Type: Chapter

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