Engineering RNA-binding proteins for biology

FEBS Journal

Volumn 280, Issue 16, 2013, Pages 3734-3754

  Chen, Yu ^a   Varani, Gabriele ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

computational design; in vitro evolution; phage display; protein engineering; protein RNA interactions; RNA recognition motif; RNA binding domains; RNA binding proteins; yeast three hybrid system; zinc finger

Indexed keywords

ANTIBODY; CARRIER PROTEIN; CCCH ZINC FINGER PROTEIN; CCHC ZINC KNUCKLE PROTEIN; DNA BINDING PROTEIN; DOUBLE STRANDED RNA; KH DOMAIN PROTEIN; MESSENGER RNA; PENTATRICOPEPTIDE REPEAT PROTEIN; PUMILIO FEM 3 BINDING FACTOR REPEAT PROTEIN; RANBP2 TYPE ZINC FINGER; REPEAT PROTEIN; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; HYBRID PROTEIN;

BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; DNA STRUCTURE; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; HUMAN; IN VITRO STUDY; MICROBIOLOGICAL PHENOMENA AND FUNCTIONS; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOLECULAR SIZE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; REVIEW; RNA RECOGNITION MOTIF; RNA STRUCTURE; SEQUENCE ANALYSIS; YEAST THREE HYBRID SYSTEM; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTATIONAL DESIGN; DRUG DESIGN; GENETICS; IN VITRO EVOLUTION; MEDICAL RESEARCH; METABOLISM; PROTEIN-RNA INTERACTIONS; RNA-BINDING DOMAINS; YEAST THREE-HYBRID SYSTEM; ZINC FINGER;

COMPUTATIONAL DESIGN; IN VITRO EVOLUTION; PHAGE DISPLAY; PROTEIN ENGINEERING; PROTEIN-RNA INTERACTIONS; RNA RECOGNITION MOTIF; RNA-BINDING DOMAINS; RNA-BINDING PROTEINS; YEAST THREE-HYBRID SYSTEM; ZINC FINGER;

ANIMALS; BIOMEDICAL RESEARCH; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; PROTEIN ENGINEERING; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT FUSION PROTEINS; RNA-BINDING PROTEINS; ZINC FINGERS;

EID: 84885928855     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12375     Document Type: Review

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