Structures of Human Pumilio with Noncognate RNAs Reveal Molecular Mechanisms for Binding Promiscuity

Structure

Volumn 16, Issue 4, 2008, Pages 549-557

  Gupta, Yogesh K ^a   Nair, Deepak T ^a   Wharton, Robin P ^b   Aggarwal, Aneel K ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

RNA

Indexed keywords

MESSENGER RNA; NUCLEOTIDE; PROTEIN; PROTEIN CYCB; PROTEIN PUF5; PUMILIO PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; BINDING SITE; COMPLEX FORMATION; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN RNA BINDING; PROTEIN STRUCTURE; REGULATORY MECHANISM; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYCLIN B; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS;

EUKARYOTA;

EID: 41449107841     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2008.01.006     Document Type: Article

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