Engineered proteins with Pumilio/fem-3 mRNA binding factor scaffold to manipulate RNA metabolism

FEBS Journal

Volumn 280, Issue 16, 2013, Pages 3755-3767

  Wang, Yang ^a   Wang, Zefeng ^a   Tanaka Hall, Traci M ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

protein engineering; protein RNA interaction; PUF protein; RNA; RNA localization; RNA regulation; RNA binding protein; splicing; translation; X ray crystallography

Indexed keywords

PUMILIO FEM 3 MESSENGER RNA BINDING FACTOR; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; DROSOPHILA PROTEIN; FEM 3 PROTEIN, C ELEGANS; FEM-3 PROTEIN, C ELEGANS; HYBRID PROTEIN; MESSENGER RNA; PUMILIO PROTEIN, DROSOPHILA; RNA;

BINDING AFFINITY; METABOLIC REGULATION; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN FUNCTION; PROTEIN RNA BINDING; REVIEW; RNA EDITING; RNA METABOLISM; RNA PROBE; RNA SEQUENCE; RNA SPLICING; RNA STABILITY; STRUCTURE ANALYSIS; TRANSCRIPTION ELONGATION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; GENETICS; HUMAN; METABOLISM; PROTEIN DOMAIN; PROTEIN-RNA INTERACTION; PUF PROTEIN; RNA LOCALIZATION; RNA REGULATION; RNA-BINDING PROTEIN; SPLICING; TRANSLATION; X-RAY CRYSTALLOGRAPHY;

PROTEIN ENGINEERING; PROTEIN-RNA INTERACTION; PUF PROTEIN; RNA; RNA LOCALIZATION; RNA REGULATION; RNA-BINDING PROTEIN; SPLICING; TRANSLATION; X-RAY CRYSTALLOGRAPHY;

ANIMALS; CAENORHABDITIS ELEGANS PROTEINS; DROSOPHILA PROTEINS; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; PROTEIN ENGINEERING; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT FUSION PROTEINS; RNA; RNA, MESSENGER; RNA-BINDING PROTEINS;

EID: 84885898647     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12367     Document Type: Review

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