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Volumn 5, Issue 1, 2013, Pages 166-179

Lineage Tracing and Cell Ablation Identify a Post-Aire-Expressing Thymic Epithelial Cell Population

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; CELL ANTIGEN; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TISSUE SPECIFIC ANTIGEN; UNCLASSIFIED DRUG;

EID: 84885854982     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.08.038     Document Type: Article
Times cited : (108)

References (54)
  • 1
    • 73149115486 scopus 로고    scopus 로고
    • Aire's partners in the molecular control of immunological tolerance
    • Abramson J., Giraud M., Benoist C., Mathis D. Aire's partners in the molecular control of immunological tolerance. Cell 2010, 140:123-135.
    • (2010) Cell , vol.140 , pp. 123-135
    • Abramson, J.1    Giraud, M.2    Benoist, C.3    Mathis, D.4
  • 2
    • 84874565064 scopus 로고    scopus 로고
    • Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance
    • Aichinger M., Wu C., Nedjic J., Klein L. Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance. J.Exp. Med. 2013, 210:287-300.
    • (2013) J.Exp. Med. , vol.210 , pp. 287-300
    • Aichinger, M.1    Wu, C.2    Nedjic, J.3    Klein, L.4
  • 4
    • 51349111243 scopus 로고    scopus 로고
    • The tumor necrosis factor family receptors RANK and CD40 cooperatively establish thethymic medullary microenvironment and self-tolerance
    • Akiyama T., Shimo Y., Yanai H., Qin J., Ohshima D., Maruyama Y., Asaumi Y., Kitazawa J., Takayanagi H., Penninger J.M., et al. The tumor necrosis factor family receptors RANK and CD40 cooperatively establish thethymic medullary microenvironment and self-tolerance. Immunity 2008, 29:423-437.
    • (2008) Immunity , vol.29 , pp. 423-437
    • Akiyama, T.1    Shimo, Y.2    Yanai, H.3    Qin, J.4    Ohshima, D.5    Maruyama, Y.6    Asaumi, Y.7    Kitazawa, J.8    Takayanagi, H.9    Penninger, J.M.10
  • 7
  • 8
    • 0041884736 scopus 로고    scopus 로고
    • Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR
    • Boehm T., Scheu S., Pfeffer K., Bleul C.C. Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. J.Exp. Med. 2003, 198:757-769.
    • (2003) J.Exp. Med. , vol.198 , pp. 757-769
    • Boehm, T.1    Scheu, S.2    Pfeffer, K.3    Bleul, C.C.4
  • 10
    • 0346599403 scopus 로고    scopus 로고
    • An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
    • Finnish-German APECED Consortium
    • An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat. Genet. 1997, 17:399-403. Finnish-German APECED Consortium.
    • (1997) Nat. Genet. , vol.17 , pp. 399-403
  • 12
    • 0035171545 scopus 로고    scopus 로고
    • Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
    • Derbinski J., Schulte A., Kyewski B., Klein L. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat. Immunol. 2001, 2:1032-1039.
    • (2001) Nat. Immunol. , vol.2 , pp. 1032-1039
    • Derbinski, J.1    Schulte, A.2    Kyewski, B.3    Klein, L.4
  • 14
    • 38649131259 scopus 로고    scopus 로고
    • Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism
    • Derbinski J., Pinto S., Rösch S., Hexel K., Kyewski B. Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism. Proc. Natl. Acad. Sci. USA 2008, 105:657-662.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 657-662
    • Derbinski, J.1    Pinto, S.2    Rösch, S.3    Hexel, K.4    Kyewski, B.5
  • 17
    • 0036864744 scopus 로고    scopus 로고
    • Organization of thymic medullary epithelial heterogeneity: implications for mechanisms of epithelial differentiation
    • Farr A.G., Dooley J.L., Erickson M. Organization of thymic medullary epithelial heterogeneity: implications for mechanisms of epithelial differentiation. Immunol. Rev. 2002, 189:20-27.
    • (2002) Immunol. Rev. , vol.189 , pp. 20-27
    • Farr, A.G.1    Dooley, J.L.2    Erickson, M.3
  • 18
    • 70249136199 scopus 로고    scopus 로고
    • Ablation and regeneration of tolerance-inducing medullary thymic epithelial cells after cyclosporine, cyclophosphamide, and dexamethasone treatment
    • Fletcher A.L., Lowen T.E., Sakkal S., Reiseger J.J., Hammett M.V., Seach N., Scott H.S., Boyd R.L., Chidgey A.P. Ablation and regeneration of tolerance-inducing medullary thymic epithelial cells after cyclosporine, cyclophosphamide, and dexamethasone treatment. J.Immunol. 2009, 183:823-831.
    • (2009) J.Immunol. , vol.183 , pp. 823-831
    • Fletcher, A.L.1    Lowen, T.E.2    Sakkal, S.3    Reiseger, J.J.4    Hammett, M.V.5    Seach, N.6    Scott, H.S.7    Boyd, R.L.8    Chidgey, A.P.9
  • 19
    • 37549071821 scopus 로고    scopus 로고
    • Promiscuous gene expression and the developmental dynamics of medullary thymic epithelial cells
    • Gäbler J., Arnold J., Kyewski B. Promiscuous gene expression and the developmental dynamics of medullary thymic epithelial cells. Eur. J. Immunol. 2007, 37:3363-3372.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 3363-3372
    • Gäbler, J.1    Arnold, J.2    Kyewski, B.3
  • 20
    • 7244227645 scopus 로고    scopus 로고
    • Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation
    • Gallegos A.M., Bevan M.J. Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation. J.Exp. Med. 2004, 200:1039-1049.
    • (2004) J.Exp. Med. , vol.200 , pp. 1039-1049
    • Gallegos, A.M.1    Bevan, M.J.2
  • 22
    • 33847350111 scopus 로고    scopus 로고
    • Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation
    • Gillard G.O., Dooley J., Erickson M., Peltonen L., Farr A.G. Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation. J.Immunol. 2007, 178:3007-3015.
    • (2007) J.Immunol. , vol.178 , pp. 3007-3015
    • Gillard, G.O.1    Dooley, J.2    Erickson, M.3    Peltonen, L.4    Farr, A.G.5
  • 23
    • 35748941369 scopus 로고    scopus 로고
    • Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire
    • Gray D., Abramson J., Benoist C., Mathis D. Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire. J.Exp. Med. 2007, 204:2521-2528.
    • (2007) J.Exp. Med. , vol.204 , pp. 2521-2528
    • Gray, D.1    Abramson, J.2    Benoist, C.3    Mathis, D.4
  • 24
    • 67549104034 scopus 로고    scopus 로고
    • Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity
    • Guerau-de-Arellano M., Martinic M., Benoist C., Mathis D. Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity. J.Exp. Med. 2009, 206:1245-1252.
    • (2009) J.Exp. Med. , vol.206 , pp. 1245-1252
    • Guerau-de-Arellano, M.1    Martinic, M.2    Benoist, C.3    Mathis, D.4
  • 25
    • 34247868281 scopus 로고    scopus 로고
    • Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin
    • Hamazaki Y., Fujita H., Kobayashi T., Choi Y., Scott H.S., Matsumoto M., Minato N. Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. Nat. Immunol. 2007, 8:304-311.
    • (2007) Nat. Immunol. , vol.8 , pp. 304-311
    • Hamazaki, Y.1    Fujita, H.2    Kobayashi, T.3    Choi, Y.4    Scott, H.S.5    Matsumoto, M.6    Minato, N.7
  • 30
    • 84872198683 scopus 로고    scopus 로고
    • Three-dimensional visualization of the mouse thymus organization in health and immunodeficiency
    • Irla M., Guenot J., Sealy G., Reith W., Imhof B.A., Sergé A. Three-dimensional visualization of the mouse thymus organization in health and immunodeficiency. J.Immunol. 2013, 190:586-596.
    • (2013) J.Immunol. , vol.190 , pp. 586-596
    • Irla, M.1    Guenot, J.2    Sealy, G.3    Reith, W.4    Imhof, B.A.5    Sergé, A.6
  • 32
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory Tcells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim J.M., Rasmussen J.P., Rudensky A.Y. Regulatory Tcells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 2007, 8:191-197.
    • (2007) Nat. Immunol. , vol.8 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 33
    • 67650507153 scopus 로고    scopus 로고
    • The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
    • Koble C., Kyewski B. The thymic medulla: a unique microenvironment for intercellular self-antigen transfer. J.Exp. Med. 2009, 206:1505-1513.
    • (2009) J.Exp. Med. , vol.206 , pp. 1505-1513
    • Koble, C.1    Kyewski, B.2
  • 34
  • 37
    • 33846470670 scopus 로고    scopus 로고
    • Controlled expression of transgenes introduced by invivo electroporation
    • Matsuda T., Cepko C.L. Controlled expression of transgenes introduced by invivo electroporation. Proc. Natl. Acad. Sci. USA 2007, 104:1027-1032.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 1027-1032
    • Matsuda, T.1    Cepko, C.L.2
  • 39
    • 79954463242 scopus 로고    scopus 로고
    • Control of central and peripheral tolerance by Aire
    • Metzger T.C., Anderson M.S. Control of central and peripheral tolerance by Aire. Immunol. Rev. 2011, 241:89-103.
    • (2011) Immunol. Rev. , vol.241 , pp. 89-103
    • Metzger, T.C.1    Anderson, M.S.2
  • 41
    • 77952302980 scopus 로고    scopus 로고
    • Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation
    • Nishikawa Y., Hirota F., Yano M., Kitajima H., Miyazaki J., Kawamoto H., Mouri Y., Matsumoto M. Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation. J.Exp. Med. 2010, 207:963-971.
    • (2010) J.Exp. Med. , vol.207 , pp. 963-971
    • Nishikawa, Y.1    Hirota, F.2    Yano, M.3    Kitajima, H.4    Miyazaki, J.5    Kawamoto, H.6    Mouri, Y.7    Matsumoto, M.8
  • 47
    • 84861134199 scopus 로고    scopus 로고
    • Defective autoimmune regulator-dependent central tolerance to myelin protein zero is linked to autoimmune peripheral neuropathy
    • Su M.A., Davini D., Cheng P., Giang K., Fan U., DeVoss J.J., Johannes K.P., Taylor L., Shum A.K., Valenzise M., et al. Defective autoimmune regulator-dependent central tolerance to myelin protein zero is linked to autoimmune peripheral neuropathy. J.Immunol. 2012, 188:4906-4912.
    • (2012) J.Immunol. , vol.188 , pp. 4906-4912
    • Su, M.A.1    Davini, D.2    Cheng, P.3    Giang, K.4    Fan, U.5    DeVoss, J.J.6    Johannes, K.P.7    Taylor, L.8    Shum, A.K.9    Valenzise, M.10
  • 48
    • 84861212351 scopus 로고    scopus 로고
    • Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection
    • Taniguchi R.T., DeVoss J.J., Moon J.J., Sidney J., Sette A., Jenkins M.K., Anderson M.S. Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection. Proc. Natl. Acad. Sci. USA 2012, 109:7847-7852.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 7847-7852
    • Taniguchi, R.T.1    DeVoss, J.J.2    Moon, J.J.3    Sidney, J.4    Sette, A.5    Jenkins, M.K.6    Anderson, M.S.7
  • 49
    • 56749184864 scopus 로고    scopus 로고
    • Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated
    • Villaseñor J., Besse W., Benoist C., Mathis D. Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated. Proc. Natl. Acad. Sci. USA 2008, 105:15854-15859.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 15854-15859
    • Villaseñor, J.1    Besse, W.2    Benoist, C.3    Mathis, D.4
  • 50
    • 84872711825 scopus 로고    scopus 로고
    • Post-Aire maturation of thymic medullary epithelial cells involves selective expression of keratinocyte-specific autoantigens
    • Wang X., Laan M., Bichele R., Kisand K., Scott H.S., Peterson P. Post-Aire maturation of thymic medullary epithelial cells involves selective expression of keratinocyte-specific autoantigens. Front. Immunol. 2012, 3:19.
    • (2012) Front. Immunol. , vol.3 , pp. 19
    • Wang, X.1    Laan, M.2    Bichele, R.3    Kisand, K.4    Scott, H.S.5    Peterson, P.6
  • 54
    • 0034662906 scopus 로고    scopus 로고
    • Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
    • Zuklys S., Balciunaite G., Agarwal A., Fasler-Kan E., Palmer E., Holländer G.A. Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J.Immunol. 2000, 165:1976-1983.
    • (2000) J.Immunol. , vol.165 , pp. 1976-1983
    • Zuklys, S.1    Balciunaite, G.2    Agarwal, A.3    Fasler-Kan, E.4    Palmer, E.5    Holländer, G.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.