Solid dispersions prepared by continuous cogrinding in an air jet mill

Journal of Pharmaceutical Sciences

Volumn 102, Issue 11, 2013, Pages 4132-4139

  Muehlenfeld, Christian ^a   Kann, Birthe ^b   Windbergs, Maike ^b,c   Thommes, Markus ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

Calorimetry (DSC); Dissolution rate; Milling; Physicochemical properties; Poorly water soluble drugs; Raman spectroscopy; Solid dispersion; Surface energy; Wetting and contact angle; X ray powder diffractometry

Indexed keywords

DRUG CARRIER; GRISEOFULVIN; MANNITOL; ANTIFUNGAL AGENT; EXCIPIENT;

ARTICLE; CONTACT ANGLE; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG FORMULATION; DRUG SOLUBILITY; GRINDING; PARTICLE SIZE; PHYSICAL CHEMISTRY; SOLID DISPERSION; X RAY POWDER DIFFRACTION; CHEMISTRY; MEDICINAL CHEMISTRY; POWDER DIFFRACTION; PROCEDURES; RAMAN SPECTROMETRY; SOLUBILITY; X RAY DIFFRACTION; CALORIMETRY (DSC); DISSOLUTION; METHODOLOGY; MILLING; PHYSICOCHEMICAL PROPERTIES; POORLY WATER-SOLUBLE DRUGS; SURFACE ENERGY; WETTING AND CONTACT ANGLE; X-RAY POWDER DIFFRACTOMETRY;

ANTIFUNGAL AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; EXCIPIENTS; GRISEOFULVIN; MANNITOL; PARTICLE SIZE; POWDER DIFFRACTION; SOLUBILITY; SPECTRUM ANALYSIS, RAMAN; X-RAY DIFFRACTION;

CALORIMETRY (DSC); DISSOLUTION RATE; MILLING; PHYSICOCHEMICAL PROPERTIES; POORLY WATER-SOLUBLE DRUGS; RAMAN SPECTROSCOPY; SOLID DISPERSION; SURFACE ENERGY; WETTING AND CONTACT ANGLE; X-RAY POWDER DIFFRACTOMETRY;

EID: 84885844345     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23731     Document Type: Article

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