Solubilization behavior of a poorly soluble drug under combined use of surfactants and cosolvents

European Journal of Pharmaceutical Sciences

Volumn 28, Issue 1-2, 2006, Pages 7-14

  Kawakami, Kohsaku ^a,b   Oda, Naohiko ^a   Miyoshi, Kyoko ^a   Funaki, Takeshi ^a   Ida, Yasuo ^a  

^a SHIONOGI AND CO LTD   (Japan)

^b BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Cosolvent; Dimethylacetoamide; Ethanol; Glycerol; Log linear model; Micelle; Polarity; Poly(ethylene glycol) 400; Sodium dodecyl sulfate; Solubility; Tween 80

Indexed keywords

ALCOHOL; DODECYL SULFATE SODIUM; GLYCEROL; MACROGOL 400; N,N DIMETHYLACETAMIDE; PHENYTOIN; POLYSORBATE 80; SOLVENT; SURFACTANT; WATER;

AQUEOUS SOLUTION; ARTICLE; DRUG SOLUBILITY; LOGLINEAR MODEL; MICELLE; MICELLIZATION; PRIORITY JOURNAL; SOLUBILIZATION; SURFACE TENSION;

ALGORITHMS; CHEMISTRY, PHARMACEUTICAL; MICELLES; MODELS, CHEMICAL; MODELS, STATISTICAL; PHARMACEUTICAL PREPARATIONS; PHENYTOIN; SOLVENTS; SURFACE TENSION; SURFACE-ACTIVE AGENTS;

EID: 33644892211     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2005.11.012     Document Type: Article

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