Simultaneous micronization and surface modification for improvement of flow and dissolution of drug particles

International Journal of Pharmaceutics

Volumn 415, Issue 1-2, 2011, Pages 185-195

  Han, Xi ^a   Ghoroi, Chinmay ^a   To, Daniel ^a   Chen, Yuhua ^a   Davé, Rajesh ^a  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Co grinding; Dissolution rate; Dry coating; Flowability; Fluid energy mill (FEM); Micronization

Indexed keywords

IBUPROFEN; SILICON DIOXIDE;

ARTICLE; BULK DENSITY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG COATING; DRUG SOLUBILITY; FLOW KINETICS; HYDROPHILICITY; PARTICLE SIZE; POWDER; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SCANNING ELECTRON MICROSCOPY; SHEAR RATE; SURFACE PROPERTY; TABLET COMPRESSION; WETTABILITY; X RAY DIFFRACTION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CRYSTALLIZATION; EQUIPMENT DESIGN; IBUPROFEN; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; POWDER DIFFRACTION; POWDERS; RHEOLOGY; SOLUBILITY; SPECTRUM ANALYSIS, RAMAN; STRESS, MECHANICAL; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL; X-RAY DIFFRACTION;

EID: 79960185799     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.05.070     Document Type: Article

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