Improvement of dissolution characteristics and bioavailability of poorly water-soluble drugs by novel cogrinding method using water-soluble polymer

International Journal of Pharmaceutics

Volumn 160, Issue 1, 1998, Pages 11-19

  Sugimoto, Masaaki ^a   Okagaki, Takuya ^a   Narisawa, Shinji ^a   Koida, Yoshiyuki ^a   Nakajima, Kingo ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Bioavailability; Coground mixture; Dissolution; Poorly water soluble drug; Solubility; Water soluble polymer

Indexed keywords

GRISEOFULVIN; HYDROXYPROPYLMETHYLCELLULOSE; INDOMETACIN; MACROGOL; MACROGOL 6000; NIFEDIPINE; POLYMER;

ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DISSOLUTION; DOG; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TECHNIQUE;

EID: 0032509855     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00293-7     Document Type: Article

References (12)

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