Investigating the relationship between drug distribution in solid lipid matrices and dissolution behaviour using Raman spectroscopy and mapping

Journal of Pharmaceutical Sciences

Volumn 99, Issue 3, 2010, Pages 1464-1475

  Windbergs, Maike ^a   Haaser, Miriam ^b   Mcgoverin, Cushla M ^b   Gordon, Keith C ^b   Kleinebudde, Peter ^a   Strachan, Clare J ^b,c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Dissolution; Extrusion; Lipids; Polyethylene glycol; Raman mapping; Raman spectroscopy; Solid lipid extrudates; Solid state; Theophylline; Tripalmitin

Indexed keywords

LIPID; MACROGOL 10000; POLYMER; THEOPHYLLINE; THEOPHYLLINE ANHYDRATE; TRIACYLGLYCEROL; TRIPALMITIN; UNCLASSIFIED DRUG;

ARTICLE; BEHAVIOR; DISPERSION; DRUG DISTRIBUTION; DRUG RELEASE; DRUG SOLUBILITY; PARTICLE SIZE; RAMAN SPECTROMETRY; SOLID STATE; SURFACE PROPERTY;

EID: 76649128991     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21894     Document Type: Article

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