Raf and PI3K are the molecular targets for the anti-metastatic effect of luteolin

Phytotherapy Research

Volumn 27, Issue 10, 2013, Pages 1481-1488

  Kim, Ho Young ^a   Jung, Sung Keun ^a   Byun, Sanguine ^a   Son, Joe Eun ^a   Oh, Mi Hyun ^a   Lee, Jihoon ^a   Kang, Min Jeong ^a   Heo, Yong Seok ^c   Lee, Ki Won ^a,b   Lee, Hyong Joo ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c Konkuk University   (South Korea)

Author keywords

lung metastasis; luteolin; MMP 2 9; PI3K; Raf kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 (3,5 DIBROMO 4 HYDROXYBENZYLIDENE) 1,3 DIHYDRO 5 IODO 2 INDOLONE; GELATINASE A; GELATINASE B; LUTEOLIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAF PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; CELL INVASION; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; WESTERN BLOTTING;

MURINAE;

LUNG METASTASIS; LUTEOLIN; MMP-2/9; PI3K; RAF KINASE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CHROMONES; INDOLES; LUNG NEOPLASMS; LUTEOLIN; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED BALB C; MORPHOLINES; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHENOLS; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RAF KINASES;

EID: 84885652402     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4888     Document Type: Article

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