PPARα and PPARγ protect against HIV-1-induced MMP-9 overexpression via caveolae-associated ERK and Akt signaling

FASEB Journal

Volumn 25, Issue 11, 2011, Pages 3979-3988

  Huang, Wen ^a   András, Ibolya E ^a   Rha, Geun Bae ^a   Hennig, Bernhard ^b   Toborek, Michal ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Bloodbrain barrier; Human immunodeficiency virus 1; Matrix metalloproteinase; Peroxisome proliferator activated receptor

Indexed keywords

FENOFIBRATE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PROTEIN KINASE B; ROSIGLITAZONE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; CAVEOLA; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; KNOCKOUT MOUSE; MICROVASCULATURE; MONOCYTE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; VIREMIA; VIRUS CELL INTERACTION; WESTERN BLOTTING;

ANIMALS; BLOOD-BRAIN BARRIER; CAVEOLAE; CAVEOLIN 1; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEK293 CELLS; HIV-1; HUMANS; MATRIX METALLOPROTEINASE 9; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PPAR ALPHA; PPAR GAMMA; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; U937 CELLS;

HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

EID: 80355129688     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-188607     Document Type: Article

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