-
1
-
-
0033568455
-
Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression
-
Abounader, R., Ranganathan, S., Lal, B., Fielding, K., Book, A., Dietz, H., et al. (1999). Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression. J. Natl. Cancer Inst. 91, 1548-1556.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 1548-1556
-
-
Abounader, R.1
Ranganathan, S.2
Lal, B.3
Fielding, K.4
Book, A.5
Dietz, H.6
-
3
-
-
78649986150
-
TGF-beta receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma
-
Anido, J., Saez-Borderias, A., Gonzalez-Junca, A., Rodon, L., Folch, G., Carmona, M. A., et al. (2010). TGF-beta receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma. Cancer Cell 18, 655-668.
-
(2010)
Cancer Cell
, vol.18
, pp. 655-668
-
-
Anido, J.1
Saez-Borderias, A.2
Gonzalez-Junca, A.3
Rodon, L.4
Folch, G.5
Carmona, M.A.6
-
4
-
-
51049101689
-
Targeting cancer stem cells through L1CAM suppresses glioma growth
-
Bao, S., Wu, Q., Li, Z., Sathornsumetee, S., Wang, H., McLendon, R. E., et al. (2008). Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res. 68, 6043-6048.
-
(2008)
Cancer Res.
, vol.68
, pp. 6043-6048
-
-
Bao, S.1
Wu, Q.2
Li, Z.3
Sathornsumetee, S.4
Wang, H.5
McLendon, R.E.6
-
5
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao, S., Wu, Q., McLendon, R. E., Hao, Y., Shi, Q., Hjelmeland, A. B., et al. (2006). Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444, 756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
-
6
-
-
70849122697
-
Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
-
doi:10.1371/journal.pone.0007752
-
Brennan, C., Momota, H., Hambardzumyan, D., Ozawa, T., Tandon, A., Pedraza, A., et al. (2009). Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS ONE 4:e7752. doi:10.1371/journal.pone.0007752
-
(2009)
PLoS ONE
, vol.4
-
-
Brennan, C.1
Momota, H.2
Hambardzumyan, D.3
Ozawa, T.4
Tandon, A.5
Pedraza, A.6
-
7
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese, C., Poppleton, H., Kocak, M., Hogg, T. L., Fuller, C., Hamner, B., et al. (2007). A perivascular niche for brain tumor stem cells. Cancer Cell 11, 69-82.
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
Hamner, B.6
-
8
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research, N. (2008). Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455, 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
Cancer Genome Atlas Research, N.1
-
9
-
-
0035912757
-
Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models
-
Cao, B., Su, Y., Oskarsson, M., Zhao, P., Kort, E. J., Fisher, R. J., et al. (2001). Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models. Proc. Natl. Acad. Sci. U.S.A. 98, 7443-7448.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 7443-7448
-
-
Cao, B.1
Su, Y.2
Oskarsson, M.3
Zhao, P.4
Kort, E.J.5
Fisher, R.J.6
-
10
-
-
0037087538
-
Survival and failure patterns of high-grade gliomas after three-dimensional conformal radiotherapy
-
Chan, J. L., Lee, S. W., Fraass, B. A., Normolle, D. P., Greenberg, H. S., Junck, L. R., et al. (2002). Survival and failure patterns of high-grade gliomas after three-dimensional conformal radiotherapy. J Clin. Oncol. 20, 1635-1642.
-
(2002)
J Clin. Oncol.
, vol.20
, pp. 1635-1642
-
-
Chan, J.L.1
Lee, S.W.2
Fraass, B.A.3
Normolle, D.P.4
Greenberg, H.S.5
Junck, L.R.6
-
11
-
-
77956803700
-
The perivascular niche microenvironment in brain tumor progression
-
Charles, N., and Holland, E. C. (2010). The perivascular niche microenvironment in brain tumor progression. Cell Cycle 9, 3012-3021.
-
(2010)
Cell Cycle
, vol.9
, pp. 3012-3021
-
-
Charles, N.1
Holland, E.C.2
-
12
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang, L., White, D. W., Gross, S., Bennett, B. D., Bittinger, M. A., Driggers, E. M., et al. (2009). Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462, 739-744.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
-
13
-
-
84865712690
-
The MET oncogene is a functional marker of a glioblastoma stem cell subtype
-
De Bacco, F., Casanova, E., Medico, E., Pellegatta, S., Orzan, F., Albano, R., et al. (2012). The MET oncogene is a functional marker of a glioblastoma stem cell subtype. Cancer Res. 72, 4537-4550.
-
(2012)
Cancer Res.
, vol.72
, pp. 4537-4550
-
-
De Bacco, F.1
Casanova, E.2
Medico, E.3
Pellegatta, S.4
Orzan, F.5
Albano, R.6
-
14
-
-
79955420135
-
Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
-
De Bacco, F., Luraghi, P., Medico, E., Reato, G., Girolami, F., Perera, T., et al. (2011). Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer. J. Natl. Cancer Inst. 103, 645-661.
-
(2011)
J. Natl. Cancer Inst.
, vol.103
, pp. 645-661
-
-
De Bacco, F.1
Luraghi, P.2
Medico, E.3
Reato, G.4
Girolami, F.5
Perera, T.6
-
15
-
-
84859847164
-
Emerging insights into the molecular and cellular basis of glioblastoma
-
Dunn, G. P., Rinne, M. L., Wykosky, J., Genovese, G., Quayle, S. N., Dunn, I. F., et al. (2012). Emerging insights into the molecular and cellular basis of glioblastoma. Genes Dev. 26, 756-784.
-
(2012)
Genes Dev.
, vol.26
, pp. 756-784
-
-
Dunn, G.P.1
Rinne, M.L.2
Wykosky, J.3
Genovese, G.4
Quayle, S.N.5
Dunn, I.F.6
-
16
-
-
75349105363
-
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
-
Fan, X., Khaki, L., Zhu, T. S., Soules, M. E., Talsma, C. E., Gul, N., et al. (2010). NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells 28, 5-16.
-
(2010)
Stem Cells
, vol.28
, pp. 5-16
-
-
Fan, X.1
Khaki, L.2
Zhu, T.S.3
Soules, M.E.4
Talsma, C.E.5
Gul, N.6
-
17
-
-
79958110216
-
Delayed cell death associated with mitotic catastrophe in gamma-irradiated stem-like glioma cells
-
Firat, E., Gaedicke, S., Tsurumi, C., Esser, N., Weyerbrock, A., and Niedermann, G. (2011). Delayed cell death associated with mitotic catastrophe in gamma-irradiated stem-like glioma cells. Radiat. Oncol. 6, 71.
-
(2011)
Radiat. Oncol.
, vol.6
, pp. 71
-
-
Firat, E.1
Gaedicke, S.2
Tsurumi, C.3
Esser, N.4
Weyerbrock, A.5
Niedermann, G.6
-
18
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli, R., Binda, E., Orfanelli, U., Cipelletti, B., Gritti, A., De Vitis, S., et al. (2004). Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res. 64, 7011-7021.
-
(2004)
Cancer Res.
, vol.64
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
Cipelletti, B.4
Gritti, A.5
De Vitis, S.6
-
19
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby, R. A., and Gillies, R. J. (2004). Why do cancers have high aerobic glycolysis? Nat. Rev. Cancer 4, 891-899.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
20
-
-
0034312277
-
Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts
-
Guo, Z., Kumagai, A., Wang, S. X., and Dunphy, W. G. (2000). Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts. Genes Dev. 14, 2745-2756.
-
(2000)
Genes Dev.
, vol.14
, pp. 2745-2756
-
-
Guo, Z.1
Kumagai, A.2
Wang, S.X.3
Dunphy, W.G.4
-
21
-
-
84865241459
-
The Notch signalling system: recent insights into the complexity of a conserved pathway
-
Guruharsha, K. G., Kankel, M. W., and Artavanis-Tsakonas, S. (2012). The Notch signalling system: recent insights into the complexity of a conserved pathway. Nat. Rev. Genet. 13, 654-666.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 654-666
-
-
Guruharsha, K.G.1
Kankel, M.W.2
Artavanis-Tsakonas, S.3
-
22
-
-
84865140762
-
Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-beta
-
Hardee, M. E., Marciscano, A. E., Medina-Ramirez, C. M., Zagzag, D., Narayana, A., Lonning, S. M., et al. (2012). Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-beta. Cancer Res. 72, 4119-4129.
-
(2012)
Cancer Res.
, vol.72
, pp. 4119-4129
-
-
Hardee, M.E.1
Marciscano, A.E.2
Medina-Ramirez, C.M.3
Zagzag, D.4
Narayana, A.5
Lonning, S.M.6
-
23
-
-
70350225829
-
The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
-
Heddleston, J. M., Li, Z., McLendon, R. E., Hjelmeland, A. B., and Rich, J. N. (2009). The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 8, 3274-3284.
-
(2009)
Cell Cycle
, vol.8
, pp. 3274-3284
-
-
Heddleston, J.M.1
Li, Z.2
McLendon, R.E.3
Hjelmeland, A.B.4
Rich, J.N.5
-
24
-
-
0036205049
-
Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells
-
Hitoshi, S., Alexson, T., Tropepe, V., Donoviel, D., Elia, A. J., Nye, J. S., et al. (2002). Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes Dev. 16, 846-858.
-
(2002)
Genes Dev.
, vol.16
, pp. 846-858
-
-
Hitoshi, S.1
Alexson, T.2
Tropepe, V.3
Donoviel, D.4
Elia, A.J.5
Nye, J.S.6
-
25
-
-
79954423356
-
Acidic stress promotes a glioma stem cell phenotype
-
Hjelmeland, A. B., Wu, Q., Heddleston, J. M., Choudhary, G. S., MacSwords, J., Lathia, J. D., et al. (2011). Acidic stress promotes a glioma stem cell phenotype. Cell Death Differ. 18, 829-840.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 829-840
-
-
Hjelmeland, A.B.1
Wu, Q.2
Heddleston, J.M.3
Choudhary, G.S.4
MacSwords, J.5
Lathia, J.D.6
-
26
-
-
0018848780
-
Assumptions in the radiotherapy of glioblastoma
-
Hochberg, F. H., and Pruitt, A. (1980). Assumptions in the radiotherapy of glioblastoma. Neurology 30, 907-911.
-
(1980)
Neurology
, vol.30
, pp. 907-911
-
-
Hochberg, F.H.1
Pruitt, A.2
-
27
-
-
77956623598
-
Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate
-
Hovinga, K. E., Shimizu, F., Wang, R., Panagiotakos, G., Van Der Heijden, M., Moayedpardazi, H., et al. (2010). Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate. Stem Cells 28, 1019-1029.
-
(2010)
Stem Cells
, vol.28
, pp. 1019-1029
-
-
Hovinga, K.E.1
Shimizu, F.2
Wang, R.3
Panagiotakos, G.4
Van Der Heijden, M.5
Moayedpardazi, H.6
-
28
-
-
0036737914
-
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
-
Ignatova, T. N., Kukekov, V. G., Laywell, E. D., Suslov, O. N., Vrionis, F. D., and Steindler, D. A. (2002). Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia 39, 193-206.
-
(2002)
Glia
, vol.39
, pp. 193-206
-
-
Ignatova, T.N.1
Kukekov, V.G.2
Laywell, E.D.3
Suslov, O.N.4
Vrionis, F.D.5
Steindler, D.A.6
-
29
-
-
48749083583
-
Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling
-
Jeon, H. M., Jin, X., Lee, J. S., Oh, S. Y., Sohn, Y. W., Park, H. J., et al. (2008). Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling. Genes Dev. 22, 2028-2033.
-
(2008)
Genes Dev.
, vol.22
, pp. 2028-2033
-
-
Jeon, H.M.1
Jin, X.2
Lee, J.S.3
Oh, S.Y.4
Sohn, Y.W.5
Park, H.J.6
-
30
-
-
84555220669
-
In vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticles
-
Jin, J., Bae, K. H., Yang, H., Lee, S. J., Kim, H., Kim, Y., et al. (2011). In vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticles. Bioconjug. Chem. 22, 2568-2572.
-
(2011)
Bioconjug. Chem.
, vol.22
, pp. 2568-2572
-
-
Jin, J.1
Bae, K.H.2
Yang, H.3
Lee, S.J.4
Kim, H.5
Kim, Y.6
-
31
-
-
84864863728
-
MET signaling regulates glioblastoma stem cells
-
Joo, K. M., Jin, J., Kim, E., Ho Kim, K., Kim, Y., Gu Kang, B., et al. (2012). MET signaling regulates glioblastoma stem cells. Cancer Res. 72, 3828-3838.
-
(2012)
Cancer Res.
, vol.72
, pp. 3828-3838
-
-
Joo, K.M.1
Jin, J.2
Kim, E.3
Ho Kim, K.4
Kim, Y.5
Gu Kang, B.6
-
32
-
-
84875723571
-
Wnt/beta-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells
-
Kim, K. H., Seol, H. J., Kim, E. H., Rheey, J., Jin, H. J., Lee, Y., et al. (2013). Wnt/beta-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells. Neuro-oncology 15, 161-171.
-
(2013)
Neuro-oncology
, vol.15
, pp. 161-171
-
-
Kim, K.H.1
Seol, H.J.2
Kim, E.H.3
Rheey, J.4
Jin, H.J.5
Lee, Y.6
-
33
-
-
58949099258
-
Prognostic significance of c-Met expression in glioblastomas
-
Kong, D. S., Song, S. Y., Kim, D. H., Joo, K. M., Yoo, J. S., Koh, J. S., et al. (2009). Prognostic significance of c-Met expression in glioblastomas. Cancer 115, 140-148.
-
(2009)
Cancer
, vol.115
, pp. 140-148
-
-
Kong, D.S.1
Song, S.Y.2
Kim, D.H.3
Joo, K.M.4
Yoo, J.S.5
Koh, J.S.6
-
34
-
-
20444467263
-
Targeting the c-Met pathway potentiates glioblastoma responses to gamma-radiation
-
Lal, B., Xia, S., Abounader, R., and Laterra, J. (2005). Targeting the c-Met pathway potentiates glioblastoma responses to gamma-radiation. Clin. Cancer Res. 11, 4479-4486.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 4479-4486
-
-
Lal, B.1
Xia, S.2
Abounader, R.3
Laterra, J.4
-
35
-
-
18744422314
-
Randomized study of brachytherapy in the initial management of patients with malignant astrocytoma
-
Laperriere, N. J., Leung, P. M., McKenzie, S., Milosevic, M., Wong, S., Glen, J., et al. (1998). Randomized study of brachytherapy in the initial management of patients with malignant astrocytoma. Int. J. Radiat. Oncol. Biol. Phys. 41, 1005-1011.
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.41
, pp. 1005-1011
-
-
Laperriere, N.J.1
Leung, P.M.2
McKenzie, S.3
Milosevic, M.4
Wong, S.5
Glen, J.6
-
36
-
-
0032924132
-
Patterns of failure following high-dose 3-D conformal radiotherapy for high-grade astrocytomas: a quantitative dosimetric study
-
Lee, S. W., Fraass, B. A., Marsh, L. H., Herbort, K., Gebarski, S. S., Martel, M. K., et al. (1999). Patterns of failure following high-dose 3-D conformal radiotherapy for high-grade astrocytomas: a quantitative dosimetric study. Int. J. Radiat. Oncol. Biol. Phys. 43, 79-88.
-
(1999)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.43
, pp. 79-88
-
-
Lee, S.W.1
Fraass, B.A.2
Marsh, L.H.3
Herbort, K.4
Gebarski, S.S.5
Martel, M.K.6
-
37
-
-
70350221952
-
MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes
-
Li, Y., Guessous, F., Zhang, Y., Dipierro, C., Kefas, B., Johnson, E., et al. (2009). MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res. 69, 7569-7576.
-
(2009)
Cancer Res.
, vol.69
, pp. 7569-7576
-
-
Li, Y.1
Guessous, F.2
Zhang, Y.3
Dipierro, C.4
Kefas, B.5
Johnson, E.6
-
38
-
-
79959971880
-
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
-
Li, Y., Li, A., Glas, M., Lal, B., Ying, M., Sang, Y., et al. (2011). c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. Proc. Natl. Acad. Sci. U.S.A. 108, 9951-9956.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 9951-9956
-
-
Li, Y.1
Li, A.2
Glas, M.3
Lal, B.4
Ying, M.5
Sang, Y.6
-
39
-
-
78650129220
-
gamma-secretase inhibitor-I enhances radiosensitivity of glioblastoma cell lines by depleting CD133+ tumor cells
-
Lin, J., Zhang, X. M., Yang, J. C., Ye, Y. B., and Luo, S. Q. (2010). gamma-secretase inhibitor-I enhances radiosensitivity of glioblastoma cell lines by depleting CD133+ tumor cells. Arch. Med. Res. 41, 519-529.
-
(2010)
Arch. Med. Res.
, vol.41
, pp. 519-529
-
-
Lin, J.1
Zhang, X.M.2
Yang, J.C.3
Ye, Y.B.4
Luo, S.Q.5
-
40
-
-
33845671339
-
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
-
Liu, G., Yuan, X., Zeng, Z., Tunici, P., Ng, H., Abdulkadir, I. R., et al. (2006). Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol. Cancer 5, 67.
-
(2006)
Mol. Cancer
, vol.5
, pp. 67
-
-
Liu, G.1
Yuan, X.2
Zeng, Z.3
Tunici, P.4
Ng, H.5
Abdulkadir, I.R.6
-
41
-
-
73449111266
-
Developing c-MET pathway inhibitors for cancer therapy: progress and challenges
-
Liu, X., Newton, R. C., and Scherle, P. A. (2010). Developing c-MET pathway inhibitors for cancer therapy: progress and challenges. Trends Mol. Med. 16, 37-45.
-
(2010)
Trends Mol. Med.
, vol.16
, pp. 37-45
-
-
Liu, X.1
Newton, R.C.2
Scherle, P.A.3
-
42
-
-
84863754907
-
VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
-
Lu, K. V., Chang, J. P., Parachoniak, C. A., Pandika, M. M., Aghi, M. K., Meyronet, D., et al. (2012). VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell 22, 21-35.
-
(2012)
Cancer Cell
, vol.22
, pp. 21-35
-
-
Lu, K.V.1
Chang, J.P.2
Parachoniak, C.A.3
Pandika, M.M.4
Aghi, M.K.5
Meyronet, D.6
-
43
-
-
33845807801
-
Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities
-
Maher, E. A., Brennan, C., Wen, P. Y., Durso, L., Ligon, K. L., Richardson, A., et al. (2006). Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities. Cancer Res. 66, 11502-11513.
-
(2006)
Cancer Res.
, vol.66
, pp. 11502-11513
-
-
Maher, E.A.1
Brennan, C.2
Wen, P.Y.3
Durso, L.4
Ligon, K.L.5
Richardson, A.6
-
44
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
Matsuoka, S., Ballif, B. A., Smogorzewska, A., McDonald, E. R. III, Hurov, K. E., Luo, J., et al. (2007). ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316, 1160-1166.
-
(2007)
Science
, vol.316
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald III, E.R.4
Hurov, K.E.5
Luo, J.6
-
45
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka, S., Huang, M., and Elledge, S. J. (1998). Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282, 1893-1897.
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
46
-
-
84890619457
-
RO4929097 and bevacizumab in treating patients with progressive or recurrent malignant glioma
-
National Cancer Institute (NCI). Bethesda, MD: National Library of Medicine. [cited Dec 12, 2012].
-
National Cancer Institute (NCI). (2000). "RO4929097 and bevacizumab in treating patients with progressive or recurrent malignant glioma," in ClinicalTrials.gov [Internet]. Bethesda, MD: National Library of Medicine. Available at: http://clinicaltrials.gov/ct2/show/NCT01189240 [cited Dec 12, 2012].
-
(2000)
ClinicalTrials.gov [Internet]
-
-
-
47
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips, H. S., Kharbanda, S., Chen, R., Forrest, W. F., Soriano, R. H., Wu, T. D., et al. (2006). Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9, 157-173.
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
Wu, T.D.6
-
48
-
-
84890783024
-
Gamma-secretase inhibitor RO4929097 and cediranib maleate in treating patients with advanced solid tumors
-
Princess Margaret Hospital, National Cancer Institute (NCI). Bethesda, MD: National Library of Medicine. [cited Dec 12, 2012].
-
Princess Margaret Hospital, National Cancer Institute (NCI). (2000a). "Gamma-secretase inhibitor RO4929097 and cediranib maleate in treating patients with advanced solid tumors," in ClinicalTrials.gov [Internet]. Bethesda, MD: National Library of Medicine. Available at: http://clinicaltrials.gov/ct2/show/NCT01131234 [cited Dec 12, 2012].
-
(2000)
ClinicalTrials.gov [Internet]
-
-
-
49
-
-
84890581011
-
RO4929097 in treating patients with recurrent invasive gliomas
-
Princess Margaret Hospital, National Cancer Institute (NCI). Bethesda, MD: National Library of Medicine. [cited Dec 12, 2012].
-
Princess Margaret Hospital, National Cancer Institute (NCI). (2000b). "RO4929097 in treating patients with recurrent invasive gliomas," in ClinicalTrials.gov[Internet]. Bethesda, MD: National Library of Medicine. Available at: http://clinicaltrials.gov/ct2/show/NCT01269411 [cited Dec 12, 2012].
-
(2000)
ClinicalTrials.gov[Internet]
-
-
-
50
-
-
50849111710
-
Rational targeting of Notch signaling in cancer
-
Rizzo, P., Osipo, C., Foreman, K., Golde, T., Osborne, B., and Miele, L. (2008). Rational targeting of Notch signaling in cancer. Oncogene 27, 5124-5131.
-
(2008)
Oncogene
, vol.27
, pp. 5124-5131
-
-
Rizzo, P.1
Osipo, C.2
Foreman, K.3
Golde, T.4
Osborne, B.5
Miele, L.6
-
51
-
-
33747790218
-
Epidemiology and molecular pathology of glioma
-
[quiz 491 p. following 516]
-
Schwartzbaum, J. A., Fisher, J. L., Aldape, K. D., and Wrensch, M. (2006). Epidemiology and molecular pathology of glioma. Nat. Clin. Pract. Neurol. 2, 494-503. [quiz 491 p. following 516].
-
(2006)
Nat. Clin. Pract. Neurol.
, vol.2
, pp. 494-503
-
-
Schwartzbaum, J.A.1
Fisher, J.L.2
Aldape, K.D.3
Wrensch, M.4
-
52
-
-
77950838848
-
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha
-
Seidel, S., Garvalov, B. K., Wirta, V., Von Stechow, L., Schanzer, A., Meletis, K., et al. (2010). A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain 133, 983-995.
-
(2010)
Brain
, vol.133
, pp. 983-995
-
-
Seidel, S.1
Garvalov, B.K.2
Wirta, V.3
Von Stechow, L.4
Schanzer, A.5
Meletis, K.6
-
53
-
-
0036705582
-
The Brain Tumor Cooperative Group NIH Trial 87-01: a randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine
-
discussion 355-347
-
Selker, R. G., Shapiro, W. R., Burger, P., Blackwood, M. S., Arena, V. C., Gilder, J. C., et al. (2002). The Brain Tumor Cooperative Group NIH Trial 87-01: a randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine. Neurosurgery 51, 343-355; discussion 355-347.
-
(2002)
Neurosurgery
, vol.51
, pp. 343-355
-
-
Selker, R.G.1
Shapiro, W.R.2
Burger, P.3
Blackwood, M.S.4
Arena, V.C.5
Gilder, J.C.6
-
54
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh, S. K., Clarke, I. D., Terasaki, M., Bonn, V. E., Hawkins, C., Squire, J., et al. (2003). Identification of a cancer stem cell in human brain tumors. Cancer Res. 63, 5821-5828.
-
(2003)
Cancer Res.
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
-
55
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh, S. K., Hawkins, C., Clarke, I. D., Squire, J. A., Bayani, J., Hide, T., et al. (2004). Identification of human brain tumour initiating cells. Nature 432, 396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
-
56
-
-
83455176258
-
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
-
Snuderl, M., Fazlollahi, L., Le, L. P., Nitta, M., Zhelyazkova, B. H., Davidson, C. J., et al. (2011). Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell 20, 810-817.
-
(2011)
Cancer Cell
, vol.20
, pp. 810-817
-
-
Snuderl, M.1
Fazlollahi, L.2
Le, L.P.3
Nitta, M.4
Zhelyazkova, B.H.5
Davidson, C.J.6
-
57
-
-
70449687092
-
Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha
-
Soeda, A., Park, M., Lee, D., Mintz, A., Androutsellis-Theotokis, A., McKay, R. D., et al. (2009). Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha. Oncogene 28, 3949-3959.
-
(2009)
Oncogene
, vol.28
, pp. 3949-3959
-
-
Soeda, A.1
Park, M.2
Lee, D.3
Mintz, A.4
Androutsellis-Theotokis, A.5
McKay, R.D.6
-
58
-
-
65349115320
-
SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma
-
Son, M. J., Woolard, K., Nam, D. H., Lee, J., and Fine, H. A. (2009). SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 4, 440-452.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 440-452
-
-
Son, M.J.1
Woolard, K.2
Nam, D.H.3
Lee, J.4
Fine, H.A.5
-
59
-
-
4744345914
-
Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol
-
Souhami, L., Seiferheld, W., Brachman, D., Podgorsak, E. B., Werner-Wasik, M., Lustig, R., et al. (2004). Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol. Int. J. Radiat. Oncol. Biol. Phys. 60, 853-860.
-
(2004)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.60
, pp. 853-860
-
-
Souhami, L.1
Seiferheld, W.2
Brachman, D.3
Podgorsak, E.B.4
Werner-Wasik, M.5
Lustig, R.6
-
60
-
-
75849133698
-
The functional role of Notch signaling in human gliomas
-
Stockhausen, M. T., Kristoffersen, K., and Poulsen, H. S. (2010). The functional role of Notch signaling in human gliomas. Neuro-oncology 12, 199-211.
-
(2010)
Neuro-oncology
, vol.12
, pp. 199-211
-
-
Stockhausen, M.T.1
Kristoffersen, K.2
Poulsen, H.S.3
-
61
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp, R., Hegi, M. E., Mason, W. P., Van Den Bent, M. J., Taphoorn, M. J., Janzer, R. C., et al. (2009). Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 10, 459-466.
-
(2009)
Lancet Oncol.
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
Van Den Bent, M.J.4
Taphoorn, M.J.5
Janzer, R.C.6
-
62
-
-
84890581011
-
RO4929097 in treating patients with recurrent or progressive glioblastoma
-
Sydney Kimmel Comprehensive Cancer Center National Cancer Institute (NCI). Bethesda MD: National Library of Medicine. [cited Dec 12 2012].
-
Sydney Kimmel Comprehensive Cancer Center, National Cancer Institute (NCI). (2000). "RO4929097 in treating patients with recurrent or progressive glioblastoma," in ClinicalTrials.gov [Internet]. Bethesda, MD: National Library of Medicine. Available at: http://clinicaltrials.gov/ct2/show/NCT01122901 [cited Dec 12, 2012].
-
(2000)
ClinicalTrials.gov [Internet]
-
-
-
63
-
-
77953276147
-
Accumulation of CD133-positive glioma cells after high-dose irradiation by Gamma Knife surgery plus external beam radiation
-
Tamura, K., Aoyagi, M., Wakimoto, H., Ando, N., Nariai, T., Yamamoto, M., et al. (2010). Accumulation of CD133-positive glioma cells after high-dose irradiation by Gamma Knife surgery plus external beam radiation. J. Neurosurg. 113, 310-318.
-
(2010)
J. Neurosurg.
, vol.113
, pp. 310-318
-
-
Tamura, K.1
Aoyagi, M.2
Wakimoto, H.3
Ando, N.4
Nariai, T.5
Yamamoto, M.6
-
64
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak, R. G., Hoadley, K. A., Purdom, E., Wang, V., Qi, Y., Wilkerson, M. D., et al. (2010). Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17, 98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
-
65
-
-
84859496112
-
Notch signaling in cancer stem cells
-
Wang, J., Sullenger, B. A., and Rich, J. N. (2012). Notch signaling in cancer stem cells. Adv. Exp. Med. Biol. 727, 174-185.
-
(2012)
Adv. Exp. Med. Biol.
, vol.727
, pp. 174-185
-
-
Wang, J.1
Sullenger, B.A.2
Rich, J.N.3
-
66
-
-
75349108271
-
Notch promotes radioresistance of glioma stem cells
-
Wang, J., Wakeman, T. P., Lathia, J. D., Hjelmeland, A. B., Wang, X. F., White, R. R., et al. (2010). Notch promotes radioresistance of glioma stem cells. Stem Cells 28, 17-28.
-
(2010)
Stem Cells
, vol.28
, pp. 17-28
-
-
Wang, J.1
Wakeman, T.P.2
Lathia, J.D.3
Hjelmeland, A.B.4
Wang, X.F.5
White, R.R.6
-
67
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan, H., Parsons, D. W., Jin, G., McLendon, R., Rasheed, B. A., Yuan, W., et al. (2009). IDH1 and IDH2 mutations in gliomas. N. Engl. J. Med. 360, 765-773.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
Yuan, W.6
-
68
-
-
77749240452
-
XL-184, a MET, VEGFR-2 and RET kinase inhibitor for the treatment of thyroid cancer, glioblastoma multiforme and NSCLC
-
Zhang, Y., Guessous, F., Kofman, A., Schiff, D., and Abounader, R. (2010). XL-184, a MET, VEGFR-2 and RET kinase inhibitor for the treatment of thyroid cancer, glioblastoma multiforme and NSCLC. IDrugs 13, 112-121.
-
(2010)
IDrugs
, vol.13
, pp. 112-121
-
-
Zhang, Y.1
Guessous, F.2
Kofman, A.3
Schiff, D.4
Abounader, R.5
-
69
-
-
0034707047
-
The DNA damage response: putting checkpoints in perspective
-
Zhou, B. B., and Elledge, S. J. (2000). The DNA damage response: putting checkpoints in perspective. Nature 408, 433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
70
-
-
80052795862
-
Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells
-
Zhu, T. S., Costello, M. A., Talsma, C. E., Flack, C. G., Crowley, J. G., Hamm, L. L., et al. (2011). Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells. Cancer Res. 71, 6061-6072.
-
(2011)
Cancer Res.
, vol.71
, pp. 6061-6072
-
-
Zhu, T.S.1
Costello, M.A.2
Talsma, C.E.3
Flack, C.G.4
Crowley, J.G.5
Hamm, L.L.6
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