Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: Report of Radiation Therapy Oncology Group 93-05 protocol

International Journal of Radiation Oncology Biology Physics

Volumn 60, Issue 3, 2004, Pages 853-860

  Souhami, Luis ^a,l   Seiferheld, Wendy ^b   Brachman, David ^c   Podgorsak, Ervin B ^a   Werner Wasik, Maria ^d   Lustig, Robert ^e   Schultz, Christopher J ^f   Sause, William ^g   Okunieff, Paul ^h   Buckner, Jan ⁱ   Zamorano, Lucia ^j   Mehta, Minesh P ^k   Curran Jr , Walter J ^d  

^a MCGILL UNIVERSITY   (Canada)

^b RADIATION THERAPY ONCOLOGY GROUP   (United States)

^c Oncology Services   (United States)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f MEDICAL COLLEGE OF WISCONSIN   (United States)

^g LDS HOSPITAL   (United States)

^h UNIVERSITY OF ROCHESTER   (United States)

ⁱ MAYO CLINIC   (United States)

^j WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^l MONTREAL GENERAL HOSPITAL   (Canada)

more..

Author keywords

Glioblastoma multiforme; Quality of life; Radiation therapy; Stereotactic radiosurgery

Indexed keywords

COGNITIVE SYSTEMS; FUNCTIONS; ONCOLOGY; PATIENT MONITORING; RANDOM PROCESSES; SURGERY;

EXTERNAL BEAM RADIATION THERAPY (EBRT); MEDIAN SURVIVAL; STEREOTACTIC RADIOSURGERY (SRS);

RADIOTHERAPY;

CARMUSTINE;

ADULT; ARTICLE; BRAIN TUMOR; CANCER SURVIVAL; CLINICAL PROTOCOL; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FOLLOW UP; GAMMA RADIATION; GLIOBLASTOMA; HUMAN; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE CARE; PRIORITY JOURNAL; QUALITY ADJUSTED LIFE YEAR; RADIATION BEAM; RADIATION DOSE; RADIOSURGERY; RANDOMIZATION; STATISTICAL SIGNIFICANCE; STEREOTAXIC SURGERY; SURVIVAL RATE;

ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC AGENTS, ALKYLATING; CARMUSTINE; COMBINED MODALITY THERAPY; FEMALE; GLIOBLASTOMA; HUMANS; MALE; MIDDLE AGED; RADIATION INJURIES; RADIOSURGERY; RADIOTHERAPY DOSAGE; SALVAGE THERAPY; SUPRATENTORIAL NEOPLASMS; SURVIVAL ANALYSIS; TREATMENT FAILURE;

EID: 4744345914     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2004.04.011     Document Type: Article

References (19)

1. Walker M.D., Strike T.A., Sheline G.E. An analysis of dose-effect relationship in the radiotherapy of malignant gliomas. Int J Radiat Oncol Biol Phys. 5:1979;1725-1731
2. Bleehen N.M., Stenning S.P. A Medical Research Council trial of two radiotherapy doses in the treatment of grades 3 and 4 astrocytoma. The Medical Research Council Brain Tumour Working Party. Br J Cancer. 64:1991;769-774
3. Hochberg F.H., Pruitt A. Assumptions in the radiotherapy of glioblastoma. Neurology. 30:1980;907-911
4. Erlich S.S., Davis R.L. Spinal subarachnoid metastasis from primary intracranial glioblastoma multiforme. Cancer. 42:1978;2854-2864
5. Loeffler J.S., Alexander E. 3rd, Shea W.M., et al. Radiosurgery as part of the initial management of patients with malignant gliomas. J Clin Oncol. 10:1992;1379-1385
6. Sarkaria J.N., Mehta M.P., Loeffler J.S., et al. Radiosurgery in the initial management of malignant gliomas survival comparison with the RTOG recursive partitioning analysis. Int J Radiat Oncol Biol Phys. 32:1995;931-941
7. Irish W.D., MacDonald D.R., Cairncross J.G. Measuring bias in uncontrolled brain tumor trials - to randomize or not to randomize? Can J Neurol Sci. 24:1997;307-312
8. Curran W.J., Scott C.B., Weinstein A.S., et al. Survival comparison of radiosurgery-eligible and -ineligible malignant glioma patients treated with hyperfractionated radiation therapy and carmustine A report of Radiation Therapy Oncology Group 83-02. J Clin Oncol. 11:1993;857-862
9. Shaw E., Kline R., Gillin M., et al. Radiation Therapy Oncology Group Radiosurgery quality assurance guidelines. Int J Radiat Oncol Biol Phys. 27:1993;1231-1239
10. Shaw E., Scott C., Souhami L., et al. Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases Final report of RTOG protocol 90-05. Int J Radiat Oncol Biol Phys. 47:2000;291-298
11. Curran W.J., Scott C.B., Horton J., et al. Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials. J Natl Cancer Inst. 85:1993;704-710
12. Kaplan E.L., Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 53:1958;457-481
13. Caplan R.J., Pajak T.F., Cox J.D. Analysis of the probability and risk of cause-specific failure. Int J Radiat Oncol Biol Phys. 29:1994;1183-1186
14. Kanji G. 100 statistical tests. London: Sage Publications; 1999
15. Gutin P.H., Prados M.D., Phillips T.L., et al. External radiation followed by an interstitial high activity iodine-125 implant boost in the initial treatment of malignant gliomas NCOG study 6G-82-2. Int J Rad Oncol Biol Phys. 21:1991;601-606
16. Kelly P.J., Daumas-Duport C., Kispert D.B., et al. Imaging-based stereotaxic serial biopsies in untreated intracranial glial neoplasms. J Neurosurgery. 66:1987;865-874
17. Castillo M., Smith J.K., Kwock L., Wilber K. Apparent diffusion coefficients in the evaluation of high-grade cerebral gliomas. Am J Neuroradiol. 22:2001;60-64
18. Laperriere N.J., Leung P.M.K., McKenzie S., et al. Randomized study of brachytherapy in the initial management of patients with malignant astrocytoma. Int J Radiat Oncol Biol Phys. 41:1998;1005-1011
19. Selker R.G., Shapiro W.R., Burger P., et al. The Brain Tumor Cooperative Group NIH trial 87-01 A randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine. Neurosurgery. 51:2002;343-355