-
1
-
-
0029782859
-
Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Cheng SY, Huang HJ, Nagane M, Ji XD, Wang D, Shih CC, Arap W, Huang CM, Cavenee WK
-
Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Cheng SY, Huang HJ, Nagane M, Ji XD, Wang D, Shih CC, Arap W, Huang CM, Cavenee WK PROC NATL ACAD SCI USA 1996 93 16 8502-8507
-
(1996)
PROC NATL ACAD SCI USA
, vol.93
, Issue.16
, pp. 8502-8507
-
-
-
3
-
-
77749257413
-
-
Exelixis and GlaxoSmithKline form broad alliance to discover and develop novel therapeutics. Exelixis Inc; GlaxoSmithKline plc PRESS RELEASE 2002 October 28
-
Exelixis and GlaxoSmithKline form broad alliance to discover and develop novel therapeutics. Exelixis Inc; GlaxoSmithKline plc PRESS RELEASE 2002 October 28
-
-
-
-
4
-
-
77749241908
-
Exelixis Inc
-
Exelixis amends collaboration with GlaxoSmithKline, January 10
-
Exelixis amends collaboration with GlaxoSmithKline. Exelixis Inc PRESS RELEASE 2005 January 10
-
(2005)
PRESS RELEASE
-
-
-
6
-
-
0035884609
-
Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2. Kunkel P, Ulbricht U, Bohlen P, Brockmann MA, Fillbrandt R, Stavrou D, Westphal M, Lamszus K
-
Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2. Kunkel P, Ulbricht U, Bohlen P, Brockmann MA, Fillbrandt R, Stavrou D, Westphal M, Lamszus K CANCER RES 2001 61 18 6624-6628
-
(2001)
CANCER RES
, vol.61
, Issue.18
, pp. 6624-6628
-
-
-
7
-
-
77749241885
-
-
A phase I dose-escalation study of the safety and pharmacokinetics of XL184, a VEGFR and MET kinase inhibitor, administered orally to subjects with advanced malignancies. Kurzrock R, Camacho L, Hong D, Ng C, Janisch L, Ratain MJ, Salgia R EJC SUPPL 2006 4 12 Abs 405
-
A phase I dose-escalation study of the safety and pharmacokinetics of XL184, a VEGFR and MET kinase inhibitor, administered orally to subjects with advanced malignancies. Kurzrock R, Camacho L, Hong D, Ng C, Janisch L, Ratain MJ, Salgia R EJC SUPPL 2006 4 12 Abs 405
-
-
-
-
8
-
-
34249075147
-
-
MET amplifcation leads to geftinib resistance in lung cancer by activating ERBb3 signaling. Engelman JA, Zejnullahu K, Mitsudomi T, Song YC, Hyland C, Park JO, Lindeman N, Gale CM, Zhao XJ, Christensen J, Kosaka T et al SCIENCE 2007 316 5827 1039-1043
-
MET amplifcation leads to geftinib resistance in lung cancer by activating ERBb3 signaling. Engelman JA, Zejnullahu K, Mitsudomi T, Song YC, Hyland C, Park JO, Lindeman N, Gale CM, Zhao XJ, Christensen J, Kosaka T et al SCIENCE 2007 316 5827 1039-1043
-
-
-
-
9
-
-
34147147730
-
-
FLT3 mutations: Biology and treatment. Small D HEMATOLOGY (AM SOC HEMATOL EDUCATION PROGRAM) 2006 178-184
-
FLT3 mutations: Biology and treatment. Small D HEMATOLOGY (AM SOC HEMATOL EDUCATION PROGRAM) 2006 178-184
-
-
-
-
10
-
-
77749279123
-
-
A phase 1 dose-escalation study of the safety and pharmacokinetics (PK) of XL184, a VEGFR and MET kinase inhibitor, administered orally to patients (pts) with advanced malignancies. Salgia R, Hong D, Sherman SI, Ng C, Frye J, Janish L, Ratain M, Kurzrock R MOL CANCER THER 2007 19 Abs A152
-
A phase 1 dose-escalation study of the safety and pharmacokinetics (PK) of XL184, a VEGFR and MET kinase inhibitor, administered orally to patients (pts) with advanced malignancies. Salgia R, Hong D, Sherman SI, Ng C, Frye J, Janish L, Ratain M, Kurzrock R MOL CANCER THER 2007 19 Abs A152
-
-
-
-
13
-
-
56849132326
-
Phase I study of XL184, a RET, VEGFR2, and MET kinase inhibitor, in patients (pts) with advanced malignancies, including pts with medullary thyroid cancer (MTC). Salgia R, Sherman S, Hong DS, Ng CS, Frye J, Janisch L, Ratain MJ, Kurzrock R
-
Abs 3522
-
Phase I study of XL184, a RET, VEGFR2, and MET kinase inhibitor, in patients (pts) with advanced malignancies, including pts with medullary thyroid cancer (MTC). Salgia R, Sherman S, Hong DS, Ng CS, Frye J, Janisch L, Ratain MJ, Kurzrock R J CLIN ONCOL 2008 26 15S Abs 3522
-
(2008)
J CLIN ONCOL
, vol.26
-
-
-
14
-
-
46749144280
-
-
Exelixis reaches agreement with FDA on special protocol assessment for XL184 phase 3 trial Exelixis Inc, June 16
-
Exelixis reaches agreement with FDA on special protocol assessment for XL184 phase 3 trial Exelixis Inc PRESS RELEASE 2008 June 16
-
(2008)
PRESS RELEASE
-
-
-
17
-
-
77749241902
-
-
Exelixis notifes GlaxoSmithKline of proof-of-concept for XL184. Exelixis Inc PRESS RELEASE 2008 July 28
-
Exelixis notifes GlaxoSmithKline of proof-of-concept for XL184. Exelixis Inc PRESS RELEASE 2008 July 28
-
-
-
-
18
-
-
77749288230
-
-
A phase I study of XL184, a MET, VEGFR2, and RET kinase inhibitor, administered orally to patients (pts) with advanced malignancies, including a subgroup of pts with medullary thyroid cancer (MTC). Kurzrock R, Sherman S, Hong D, Ng C, Frye J, Janisch L, Ratain MJ, Salgia R EORTC-NCI-AACR INT CONGRESS 2008 20 October 23 Abs 379
-
A phase I study of XL184, a MET, VEGFR2, and RET kinase inhibitor, administered orally to patients (pts) with advanced malignancies, including a subgroup of pts with medullary thyroid cancer (MTC). Kurzrock R, Sherman S, Hong D, Ng C, Frye J, Janisch L, Ratain MJ, Salgia R EORTC-NCI-AACR INT CONGRESS 2008 20 October 23 Abs 379
-
-
-
-
19
-
-
77749241901
-
-
Targeting MET with XL184 to reverse EGFR tyrosine kinase inhibitor (TKI) resistance in NSCLC: Impact of preclinical studies on clinical trial design. Janne PA, Wax M, Leach J, Shankar G, Engelman J EORTC-NCI-AACR INT CONGRESS 2008 20 Abs 552
-
Targeting MET with XL184 to reverse EGFR tyrosine kinase inhibitor (TKI) resistance in NSCLC: Impact of preclinical studies on clinical trial design. Janne PA, Wax M, Leach J, Shankar G, Engelman J EORTC-NCI-AACR INT CONGRESS 2008 20 Abs 552
-
-
-
-
20
-
-
77749241907
-
-
Exelixis retains rights to develop and commercialize XL184. Exelixis Inc PRESS RELEASE 2008 October 23
-
Exelixis retains rights to develop and commercialize XL184. Exelixis Inc PRESS RELEASE 2008 October 23
-
-
-
-
21
-
-
77749257411
-
Bristol-Myers Squibb Co
-
Bristol-Myers Squibb and Exelixis enter global collaboration on two novel cancer programs, December 12
-
Bristol-Myers Squibb and Exelixis enter global collaboration on two novel cancer programs. Bristol-Myers Squibb Co PRESS RELEASE 2008 December 12
-
(2008)
PRESS RELEASE
-
-
-
22
-
-
77749257410
-
-
Bristol-Myers Squibb: In the pipeline. Bristol-Myers Squibb Co COMPANY WORLD WIDE WEB SITE 2009 January 15
-
Bristol-Myers Squibb: In the pipeline. Bristol-Myers Squibb Co COMPANY WORLD WIDE WEB SITE 2009 January 15
-
-
-
-
23
-
-
77749279135
-
De Groot JF, Prados M, Urquhart T, Robertson S, Yaron Y, Sorensen AG, Norton A, Batchelor T, Drappatz J, Wen P
-
A phase II study of XL184 in patients (pts) with progressive glioblastoma multiforme (GBM) in frst or second relapse, Abs 2047
-
A phase II study of XL184 in patients (pts) with progressive glioblastoma multiforme (GBM) in frst or second relapse. De Groot JF, Prados M, Urquhart T, Robertson S, Yaron Y, Sorensen AG, Norton A, Batchelor T, Drappatz J, Wen P J CLIN ONCOL 2009 27 15S Abs 2047
-
(2009)
J CLIN ONCOL
, vol.27
-
-
-
24
-
-
77749279136
-
an inhibitor of multiple receptor tyrosine kinases: Results from a phase II study. Sorensen AG, Jenning D, Wang M, Andronesi O, Chen P, Prados M, Wen P, Jackson E, Cha S, De Groot J
-
Use of neurovascular imaging in GBM patients (pts) to quantify early physiologic changes after treatment with XL184, Abs 2048
-
Use of neurovascular imaging in GBM patients (pts) to quantify early physiologic changes after treatment with XL184, an inhibitor of multiple receptor tyrosine kinases: Results from a phase II study. Sorensen AG, Jenning D, Wang M, Andronesi O, Chen P, Prados M, Wen P, Jackson E, Cha S, De Groot J J CLIN ONCOL 2009 27 15S Abs 2048
-
(2009)
J CLIN ONCOL
, vol.27
-
-
-
25
-
-
76749103247
-
Correlative tumor molecular profling and plasma biomarker analysis in a phase II study of XL184 in patients with progressive or recurrent glioblastoma multiforme (GBM). DePrimo S, Wu B, Huang S, Bautista R, Cancilla B, Vysotskaia V, De Groot J, Prados M, Buller R, Wen P
-
Abs 2049
-
Correlative tumor molecular profling and plasma biomarker analysis in a phase II study of XL184 in patients with progressive or recurrent glioblastoma multiforme (GBM). DePrimo S, Wu B, Huang S, Bautista R, Cancilla B, Vysotskaia V, De Groot J, Prados M, Buller R, Wen P J CLIN ONCOL 2009 27 15S Abs 2049
-
(2009)
J CLIN ONCOL
, vol.27
-
-
-
28
-
-
77749257409
-
-
Preliminary results of a phase 1 study of XL184, a MET, VEGFR2 and RET kinase inhibitor (TKI), administered orally to patients with medulllary thyroid cancer (MTC). Kurzrock R, Sherman S, Pfster D, Cohen RB, Ball D, Hong D, Ng C, Frye J, Janisch L, Ratain MJ, Salgia R ACTA MED PORT 2009 Abs OP01
-
Preliminary results of a phase 1 study of XL184, a MET, VEGFR2 and RET kinase inhibitor (TKI), administered orally to patients with medulllary thyroid cancer (MTC). Kurzrock R, Sherman S, Pfster D, Cohen RB, Ball D, Hong D, Ng C, Frye J, Janisch L, Ratain MJ, Salgia R ACTA MED PORT 2009 Abs OP01
-
-
-
-
29
-
-
77749288227
-
-
A phase I dose-escalation study of the safety and pharmacokinetics (PK) of XL184, a VEGFR and MET kinase inhibitor, administered orally to patients (pts) with advanced malignancies. Salgia R, Hong DS, Camacho LH, Ng CS, Janisch L, Ratain MJ, Kurzrock R J CLIN ONCOL 2007 25 18S Abs 14031
-
A phase I dose-escalation study of the safety and pharmacokinetics (PK) of XL184, a VEGFR and MET kinase inhibitor, administered orally to patients (pts) with advanced malignancies. Salgia R, Hong DS, Camacho LH, Ng CS, Janisch L, Ratain MJ, Kurzrock R J CLIN ONCOL 2007 25 18S Abs 14031
-
-
-
-
30
-
-
27644543354
-
-
Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis. Abounader R, Laterra J NEURO-ONCOLOGY 2005 7 4 436-451
-
Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis. Abounader R, Laterra J NEURO-ONCOLOGY 2005 7 4 436-451
-
-
-
-
31
-
-
85047681729
-
Expression and localization of scatter factor/hepatocyte growth factor in human astrocytomas. Kunkel P, Muller S, Schirmacher P, Stavrou D, Fillbrandt R, Westphal M, Lamszus K
-
Expression and localization of scatter factor/hepatocyte growth factor in human astrocytomas. Kunkel P, Muller S, Schirmacher P, Stavrou D, Fillbrandt R, Westphal M, Lamszus K NEURO-ONCOLOGY 2001 3 2 82-88
-
(2001)
NEURO-ONCOLOGY
, vol.3
, Issue.2
, pp. 82-88
-
-
-
32
-
-
58949099258
-
-
Prognostic signifcance of c-Met expression in glioblastomas. Kong DS, Song SY, Kim DH, Joo KM, Yoo JS, Koh JS, Dong SM, Suh YL, Lee JI, Park K, Kim JH et al CANCER 2009 115 1 140-148
-
Prognostic signifcance of c-Met expression in glioblastomas. Kong DS, Song SY, Kim DH, Joo KM, Yoo JS, Koh JS, Dong SM, Suh YL, Lee JI, Park K, Kim JH et al CANCER 2009 115 1 140-148
-
-
-
-
33
-
-
0031587985
-
-
Scatter factor hepatocyte growth factor expression enhances human glioblastoma tumorigenicity and growth. Laterra J, Rosen E, Nam M, Ranganathan S, Fielding K, Johnston P BIOCHEM BIOPHYS RES COMMUN 1997 235 3 743-747
-
Scatter factor hepatocyte growth factor expression enhances human glioblastoma tumorigenicity and growth. Laterra J, Rosen E, Nam M, Ranganathan S, Fielding K, Johnston P BIOCHEM BIOPHYS RES COMMUN 1997 235 3 743-747
-
-
-
-
34
-
-
15444355527
-
-
Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells. Lamszus K, Schmidt NO, Jin L, Laterra J, Zagzag D, Way D, Witte M, Weinand M, Goldberg ID, Westphal M, Rosen EM INT J CANCER 1998 75 1 19-28
-
Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells. Lamszus K, Schmidt NO, Jin L, Laterra J, Zagzag D, Way D, Witte M, Weinand M, Goldberg ID, Westphal M, Rosen EM INT J CANCER 1998 75 1 19-28
-
-
-
-
35
-
-
0036365052
-
In vivo targeting of SF/HGF and c-Met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis. Abounader R, Lal B, Luddy C, Koe G, Davidson B, Rosen EM, Laterra J
-
In vivo targeting of SF/HGF and c-Met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis. Abounader R, Lal B, Luddy C, Koe G, Davidson B, Rosen EM, Laterra J FASEB J 2002 16 1 108-110
-
(2002)
FASEB J
, vol.16
, Issue.1
, pp. 108-110
-
-
-
36
-
-
0033568455
-
Abounader R, Ranganathan S, Lal B, Fielding K, Book A, Dietz H, Burger P, Laterra J
-
Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-Met expression
-
Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-Met expression. Abounader R, Ranganathan S, Lal B, Fielding K, Book A, Dietz H, Burger P, Laterra J J NATL CANCER INST 1999 91 18 1548-1556
-
(1999)
J NATL CANCER INST
, vol.91
, Issue.18
, pp. 1548-1556
-
-
-
37
-
-
54949156454
-
Inhibitors of vascular endothelial growth factor in cancer. Pourgholami MH, Morris DL
-
Inhibitors of vascular endothelial growth factor in cancer. Pourgholami MH, Morris DL CARDIOvASC HEMATOL AGENTS MED CHEM 2008 6 4 343-347
-
(2008)
CARDIOvASC HEMATOL AGENTS MED CHEM
, vol.6
, Issue.4
, pp. 343-347
-
-
-
38
-
-
43849107087
-
Dysregulated ret signaling in thyroid cancer. Castellone MD, Santoro M
-
Dysregulated ret signaling in thyroid cancer. Castellone MD, Santoro M ENDOCRINOL METAB CLIN N AM 2008 37 2 363-374
-
(2008)
ENDOCRINOL METAB CLIN N AM
, vol.37
, Issue.2
, pp. 363-374
-
-
-
39
-
-
66849132541
-
Constitutive ret tyrosine kinase activation in hereditary medullary thyroid cancer: Clinical opportunities. Machens A, Lorenz K, Dralle H
-
Constitutive ret tyrosine kinase activation in hereditary medullary thyroid cancer: Clinical opportunities. Machens A, Lorenz K, Dralle H J INTERN MED 2009 266 1 114-125
-
(2009)
J INTERN MED
, vol.266
, Issue.1
, pp. 114-125
-
-
-
40
-
-
33750596636
-
Mechanisms of disease: Cancer targeting and the impact of oncogenic ret for medullary thyroid carcinoma therapy. Drosten M, Putzer BM
-
Mechanisms of disease: Cancer targeting and the impact of oncogenic ret for medullary thyroid carcinoma therapy. Drosten M, Putzer BM NAT CLIN PRACT ONCOL 2006 3 10 564-574
-
(2006)
NAT CLIN PRACT ONCOL
, vol.3
, Issue.10
, pp. 564-574
-
-
-
41
-
-
48249125791
-
Malignant gliomas in adults. Wen PY, Kesari S
-
Malignant gliomas in adults. Wen PY, Kesari S N ENGL J MED 2008 359 5 492-507
-
(2008)
N ENGL J MED
, vol.359
, Issue.5
, pp. 492-507
-
-
-
42
-
-
54549108740
-
Comprehensive genomic characterization defnes human glioblastoma genes and core pathways
-
Comprehensive genomic characterization defnes human glioblastoma genes and core pathways. NATURE 2008 455 7216 1061-1068
-
(2008)
NATURE
, vol.455
, Issue.7216
, pp. 1061-1068
-
-
-
43
-
-
52649131951
-
-
Lung cancer. Herbst RS, Heymach JV, Lippman SM N ENGL J MED 2008 359 13 1367-1380
-
Lung cancer. Herbst RS, Heymach JV, Lippman SM N ENGL J MED 2008 359 13 1367-1380
-
-
-
-
44
-
-
65349149344
-
Emerging therapeutic targets in non-small cell lung cancer. Dy GK, Adjei AA
-
Emerging therapeutic targets in non-small cell lung cancer. Dy GK, Adjei AA PROC AM THORAC SOC 2009 6 2 218-223
-
(2009)
PROC AM THORAC SOC
, vol.6
, Issue.2
, pp. 218-223
-
-
-
45
-
-
65349189877
-
Angiogenesis in the treatment of non-small cell lung cancer. Horn L, Sandler AB
-
Angiogenesis in the treatment of non-small cell lung cancer. Horn L, Sandler AB PROC AM THORAC SOC 2009 6 2 206-217
-
(2009)
PROC AM THORAC SOC
, vol.6
, Issue.2
, pp. 206-217
-
-
-
46
-
-
0036188465
-
Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer. Maulik G, Kijima T, Ma PC, Ghosh SK, Lin J, Shapiro GI, Schaefer E, Tibaldi E, Johnson BE, Salgia R
-
Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer. Maulik G, Kijima T, Ma PC, Ghosh SK, Lin J, Shapiro GI, Schaefer E, Tibaldi E, Johnson BE, Salgia R CLIN CANCER RES 2002 8 2 620-627
-
(2002)
CLIN CANCER RES
, vol.8
, Issue.2
, pp. 620-627
-
-
-
47
-
-
13944276728
-
-
Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Ma PC, Jagadeeswaran R, Jagadeesh S, Tretiakova MS, Nallasura V, Fox EA, Hansen M, Schaefer E, Naoki K, Lader A, Richards W et al CANCER RES 2005 65 4 1479-1488
-
Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Ma PC, Jagadeeswaran R, Jagadeesh S, Tretiakova MS, Nallasura V, Fox EA, Hansen M, Schaefer E, Naoki K, Lader A, Richards W et al CANCER RES 2005 65 4 1479-1488
-
-
-
-
48
-
-
35348822482
-
-
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Stommel JM, Kimmelman AC, Ying HQ, Nabioullin R, Ponugoti AH, Wiedemeyer R, Stegh AH, Bradner JE, Ligon KL, Brennan C, Chin L et al SCIENCE 2007 318 5848 287-290
-
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Stommel JM, Kimmelman AC, Ying HQ, Nabioullin R, Ponugoti AH, Wiedemeyer R, Stegh AH, Bradner JE, Ligon KL, Brennan C, Chin L et al SCIENCE 2007 318 5848 287-290
-
-
-
-
49
-
-
67649200247
-
Treatment effects and escape mechanisms. Miletic H, Niclou SP, Johansson M, Bjerkvig R
-
Anti-VEGF therapies for malignant glioma
-
Anti-VEGF therapies for malignant glioma: Treatment effects and escape mechanisms. Miletic H, Niclou SP, Johansson M, Bjerkvig R EXPERT OPIN THER TARGETS 2009 13 4 455-468
-
(2009)
EXPERT OPIN THER TARGETS
, vol.13
, Issue.4
, pp. 455-468
-
-
-
50
-
-
77749241895
-
-
A phase 2 study of XL184, an inhibitor of MET, VEGFR2, and RET, in patients with progressive glioblastoma multiforme. Wen P, Prados M, Chamberlain M, Cloughesy T, Drappatz J, Mikkelson T, Norden A, Weitzman R, Reardon D, Schiff D, de Groot J JOINT MEET SOC NEURO-ONCOL AANS/CNS SECT TUMORS 2009 Abs 599
-
A phase 2 study of XL184, an inhibitor of MET, VEGFR2, and RET, in patients with progressive glioblastoma multiforme. Wen P, Prados M, Chamberlain M, Cloughesy T, Drappatz J, Mikkelson T, Norden A, Weitzman R, Reardon D, Schiff D, de Groot J JOINT MEET SOC NEURO-ONCOL AANS/CNS SECT TUMORS 2009 Abs 599
-
-
-
-
51
-
-
77749279134
-
-
Reduction of tumor invasiveness and metastasis and prolongation of survival of RIP-Tag2 mice after inhibition of VEGFR plus c-Met by XL184. Sennino B, Naylor RM, Tabruyn SP, You W-K, Aftab DT, McDonald DM AACR-NCI-EORTC INT CONGRESS 2009 21 Abs A13
-
Reduction of tumor invasiveness and metastasis and prolongation of survival of RIP-Tag2 mice after inhibition of VEGFR plus c-Met by XL184. Sennino B, Naylor RM, Tabruyn SP, You W-K, Aftab DT, McDonald DM AACR-NCI-EORTC INT CONGRESS 2009 21 Abs A13
-
-
-
-
52
-
-
23944515326
-
Intracellular signal transduction pathway proteins as targets for cancer therapy. Adjei AA, Hidalgo M
-
Intracellular signal transduction pathway proteins as targets for cancer therapy. Adjei AA, Hidalgo M J CLIN ONCOL 2005 23 23 5386-5403
-
(2005)
J CLIN ONCOL
, vol.23
, Issue.23
, pp. 5386-5403
-
-
-
53
-
-
33845356681
-
Medullary thyroid cancer: Therapeutic targets and molecular markers. Ball DW
-
Medullary thyroid cancer: Therapeutic targets and molecular markers. Ball DW CURR OPIN ONCOL 2007 19 1 18-23
-
(2007)
CURR OPIN ONCOL
, vol.19
, Issue.1
, pp. 18-23
-
-
-
54
-
-
32944479646
-
Therapeutic advances in the treatment of glioblastoma: Rationale and potential role of targeted agents Reardon DA, Wen PY
-
Therapeutic advances in the treatment of glioblastoma: Rationale and potential role of targeted agents Reardon DA, Wen PY ONCOLOGIST 2006 11 2 152-164
-
(2006)
ONCOLOGIST
, vol.11
, Issue.2
, pp. 152-164
-
-
-
55
-
-
31444437952
-
Donovan EA, Kummar S
-
Targeting VEGF in cancer therapy
-
Targeting VEGF in cancer therapy. Donovan EA, Kummar S CURR PROBL CANCER 2006 30 1 7-32
-
(2006)
CURR PROBL CANCER
, vol.30
, Issue.1
, pp. 7-32
-
-
-
56
-
-
66249118670
-
-
Vandetanib (ZD6474), a dual inhibitor of vascular endothelial growth factor receptor (VEGFR) and epidermal growth factor receptor (EGFR) tyrosine kinases: Current status and future directions. Morabito A, Piccirillo MC, Falasconi F, De Feo G, Del Giudice A, Bryce J, Di Maio M, De Maio E, Normanno N, Perrone F ONCOLOGIST 2009 14 4 378-390
-
Vandetanib (ZD6474), a dual inhibitor of vascular endothelial growth factor receptor (VEGFR) and epidermal growth factor receptor (EGFR) tyrosine kinases: Current status and future directions. Morabito A, Piccirillo MC, Falasconi F, De Feo G, Del Giudice A, Bryce J, Di Maio M, De Maio E, Normanno N, Perrone F ONCOLOGIST 2009 14 4 378-390
-
-
-
-
57
-
-
77749288221
-
Signal transduction via the stem cell factor receptor/c-Kit. Ronnstrand L
-
Signal transduction via the stem cell factor receptor/c-Kit. Ronnstrand L CELL MOL LIFE SCI 2009 61 19-20 2535-2548
-
(2009)
CELL MOL LIFE SCI
, vol.61
-
-
-
58
-
-
61749101239
-
Suppression of Tie-1 in endothelial cells in vitro induces a change in the genome-wide expression profle refecting an infammatory function. Chan B, Sukhatme VP
-
Suppression of Tie-1 in endothelial cells in vitro induces a change in the genome-wide expression profle refecting an infammatory function. Chan B, Sukhatme VP FEbS LETT 2009 583 6 1023-1028
-
(2009)
FEbS LETT
, vol.583
, Issue.6
, pp. 1023-1028
-
-
-
59
-
-
4644327063
-
Medullary thyroid carcinoma. Leboulleux S, Baudin E, Travagli JP, Schlumberger M
-
Medullary thyroid carcinoma. Leboulleux S, Baudin E, Travagli JP, Schlumberger M CLIN ENDOCRINOL 2004 61 3 299-310
-
(2004)
CLIN ENDOCRINOL
, vol.61
, Issue.3
, pp. 299-310
-
-
-
60
-
-
42149192674
-
Glioblastoma multiforme: An emerging paradigm of anti-VEGF therapy. Reardon DA, Wen PY, Desjardins A, Batchelor TT, Vredenburgh JJ
-
Glioblastoma multiforme: An emerging paradigm of anti-VEGF therapy. Reardon DA, Wen PY, Desjardins A, Batchelor TT, Vredenburgh JJ EXPERT OPIN bIOL THER 2008 8 4 541-553
-
(2008)
EXPERT OPIN bIOL THER
, vol.8
, Issue.4
, pp. 541-553
-
-
-
61
-
-
1242293090
-
Emerging role of epidermal growth factor receptor inhibition in therapy for advanced malignancy: Focus on NSCLC. Langer CJ
-
Emerging role of epidermal growth factor receptor inhibition in therapy for advanced malignancy: Focus on NSCLC. Langer CJ INT J RADIAT ONCOL BIOL PHYS 2004 58 3 991-1002
-
(2004)
INT J RADIAT ONCOL BIOL PHYS
, vol.58
, Issue.3
, pp. 991-1002
-
-
-
62
-
-
1542719213
-
as prognostic indicators in NSCLC. Iwasaki A, Kuwahara M, Yoshinaga Y, Shirakusa T
-
Basic fbroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) levels
-
Basic fbroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) levels, as prognostic indicators in NSCLC. Iwasaki A, Kuwahara M, Yoshinaga Y, Shirakusa T EUR J CARDIOTHORAC SURG 2004 25 3 443-448
-
(2004)
EUR J CARDIOTHORAC SURG
, vol.25
, Issue.3
, pp. 443-448
-
-
-
63
-
-
58049192366
-
Cipriani NA, Abidoye OO, Vokes E, Salgia R
-
MET as a target for treatment of chest tumors
-
MET as a target for treatment of chest tumors. Cipriani NA, Abidoye OO, Vokes E, Salgia R LUNG CANCER 2009 63 2 169-179
-
(2009)
LUNG CANCER
, vol.63
, Issue.2
, pp. 169-179
-
-
-
64
-
-
52649131951
-
-
Lung cancer. Herbst RS, Heymach JV, Lippman SM N ENGL J MED 2008 359 13 1367-1380
-
Lung cancer. Herbst RS, Heymach JV, Lippman SM N ENGL J MED 2008 359 13 1367-1380
-
-
-
|