-
1
-
-
70350780570
-
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways
-
Alarcon, C., Zaromytidou, A. I., Xi, Q., Gao, S., Yu, J., Fujisawa, S., et al. (2009). Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell 139, 757-769.
-
(2009)
Cell
, vol.139
, pp. 757-769
-
-
Alarcon, C.1
Zaromytidou, A.I.2
Xi, Q.3
Gao, S.4
Yu, J.5
Fujisawa, S.6
-
2
-
-
45949110751
-
PML enhances the regulation of p53 by CK1 in response to DNA damage
-
Alsheich-Bartok, O., Haupt, S., Alkalay-Snir, I., Saito, S., Appella, E., and Haupt, Y. (2008). PML enhances the regulation of p53 by CK1 in response to DNA damage. Oncogene 27, 3653-3661.
-
(2008)
Oncogene
, vol.27
, pp. 3653-3661
-
-
Alsheich-Bartok, O.1
Haupt, S.2
Alkalay-Snir, I.3
Saito, S.4
Appella, E.5
Haupt, Y.6
-
3
-
-
61749089153
-
The FERM-domain protein expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie
-
Badouel, C., Gardano, L., Amin, N., Garg, A., Rosenfeld, R., Le Bihan, T., et al. (2009). The FERM-domain protein expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie. Dev. Cell 16, 411-420.
-
(2009)
Dev. Cell
, vol.16
, pp. 411-420
-
-
Badouel, C.1
Gardano, L.2
Amin, N.3
Garg, A.4
Rosenfeld, R.5
Le Bihan, T.6
-
4
-
-
0037249343
-
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis
-
Basu, S., Totty, N. F., Irwin, M. S., Sudol, M., and Downward, J. (2003). Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. Mol. Cell 11, 11-23.
-
(2003)
Mol. Cell
, vol.11
, pp. 11-23
-
-
Basu, S.1
Totty, N.F.2
Irwin, M.S.3
Sudol, M.4
Downward, J.5
-
5
-
-
36448975490
-
Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies
-
Bernardi, R., and Pandolfi, P. P. (2007). Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies. Nat. Rev. Mol. Cell Biol. 8, 1006-1016.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 1006-1016
-
-
Bernardi, R.1
Pandolfi, P.P.2
-
6
-
-
2942657482
-
Ubiquitin-dependent degradation of p73 is inhibited by PML
-
Bernassola, F., Salomoni, P., Oberst, A., Di Como, C. J., Pagano, M., Melino, G., et al. (2004). Ubiquitin-dependent degradation of p73 is inhibited by PML. J. Exp. Med. 199, 1545-1557.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1545-1557
-
-
Bernassola, F.1
Salomoni, P.2
Oberst, A.3
Di Como, C.J.4
Pagano, M.5
Melino, G.6
-
7
-
-
60749112337
-
YAP: at the crossroad between transformation and tumor suppression
-
Bertini, E., Oka, T., Sudol, M., Strano, S., and Blandino, G. (2009). YAP: at the crossroad between transformation and tumor suppression. Cell Cycle 8, 49-57.
-
(2009)
Cell Cycle
, vol.8
, pp. 49-57
-
-
Bertini, E.1
Oka, T.2
Sudol, M.3
Strano, S.4
Blandino, G.5
-
8
-
-
0027725232
-
Expanded, a negative regulator of cell proliferation in Drosophila, shows homology to the NF2 tumor suppressor
-
Boedigheimer, M., Bryant, P., and Laughon, A. (1993). Expanded, a negative regulator of cell proliferation in Drosophila, shows homology to the NF2 tumor suppressor. Mech. Dev. 44, 83-84.
-
(1993)
Mech. Dev.
, vol.44
, pp. 83-84
-
-
Boedigheimer, M.1
Bryant, P.2
Laughon, A.3
-
9
-
-
0027988814
-
The WW domain: a signalling site in dystrophin?
-
Bork, P., and Sudol, M. (1994). The WW domain: a signalling site in dystrophin? Trends Biochem. Sci. 19, 531-533.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 531-533
-
-
Bork, P.1
Sudol, M.2
-
10
-
-
79953223677
-
Hippo pathway-independent restriction of TAZ and YAP by angiomotin
-
Chan, S. W., Lim, C. J., Chong, Y. F., Pobbati, A. V., Huang, C., and Hong, W. (2011). Hippo pathway-independent restriction of TAZ and YAP by angiomotin. J. Biol. Chem. 286, 7018-7026.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 7018-7026
-
-
Chan, S.W.1
Lim, C.J.2
Chong, Y.F.3
Pobbati, A.V.4
Huang, C.5
Hong, W.6
-
11
-
-
77957676987
-
The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila
-
Chen, C. L., Gajewski, K. M., Hamaratoglu, F., Bossuyt, W., Sansores-Garcia, L., Tao, C., et al. (2010). The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila. Proc. Natl. Acad. Sci. U.S.A. 107, 15810-15815.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 15810-15815
-
-
Chen, C.L.1
Gajewski, K.M.2
Hamaratoglu, F.3
Bossuyt, W.4
Sansores-Garcia, L.5
Tao, C.6
-
12
-
-
0030858496
-
Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands
-
Chen, H. I., Einbond, A., Kwak, S. J., Linn, H., Koepf, E., Peterson, S., et al. (1997). Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. J. Biol. Chem. 272, 17070-17077.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17070-17077
-
-
Chen, H.I.1
Einbond, A.2
Kwak, S.J.3
Linn, H.4
Koepf, E.5
Peterson, S.6
-
13
-
-
0029099161
-
The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules
-
Chen, H. I., and Sudol, M. (1995). The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules. Proc. Natl. Acad. Sci. U.S.A. 92, 7819-7823.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 7819-7823
-
-
Chen, H.I.1
Sudol, M.2
-
14
-
-
33749125438
-
Delineation of a Fat tumor suppressor pathway
-
Cho, E., Feng, Y., Rauskolb, C., Maitra, S., Fehon, R., and Irvine, K. D. (2006). Delineation of a Fat tumor suppressor pathway. Nat. Genet. 38, 1142-1150.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1142-1150
-
-
Cho, E.1
Feng, Y.2
Rauskolb, C.3
Maitra, S.4
Fehon, R.5
Irvine, K.D.6
-
15
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi, M., Zanconato, F., Azzolin, L., Forcato, M., Rosato, A., Frasson, C., et al. (2011). The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell 147, 759-772.
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
Forcato, M.4
Rosato, A.5
Frasson, C.6
-
16
-
-
1542285168
-
PML is a direct p53 target that modulates p53 effector functions
-
de Stanchina, E., Querido, E., Narita, M., Davuluri, R. V., Pandolfi, P. P., Ferbeyre, G., et al. (2004). PML is a direct p53 target that modulates p53 effector functions. Mol. Cell 13, 523-535.
-
(2004)
Mol. Cell
, vol.13
, pp. 523-535
-
-
de Stanchina, E.1
Querido, E.2
Narita, M.3
Davuluri, R.V.4
Pandolfi, P.P.5
Ferbeyre, G.6
-
17
-
-
34548636132
-
Elucidation of a universal size-control mechanism in Drosophila and mammals
-
Dong, J., Feldmann, G., Huang, J., Wu, S., Zhang, N., Comerford, S. A., et al. (2007a). Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 130, 1120-1133.
-
(2007)
Cell
, vol.130
, pp. 1120-1133
-
-
Dong, J.1
Feldmann, G.2
Huang, J.3
Wu, S.4
Zhang, N.5
Comerford, S.A.6
-
18
-
-
34347395347
-
14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells
-
Dong, S., Kang, S., Gu, T. L., Kardar, S., Fu, H., Lonial, S., et al. (2007b). 14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells. Blood 110, 360-369.
-
(2007)
Blood
, vol.110
, pp. 360-369
-
-
Dong, S.1
Kang, S.2
Gu, T.L.3
Kardar, S.4
Fu, H.5
Lonial, S.6
-
19
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
Dupont, S., Morsut, L., Aragona, M., Enzo, E., Giulitti, S., Cordenonsi, M., et al. (2011). Role of YAP/TAZ in mechanotransduction. Nature 474, 179-183.
-
(2011)
Nature
, vol.474
, pp. 179-183
-
-
Dupont, S.1
Morsut, L.2
Aragona, M.3
Enzo, E.4
Giulitti, S.5
Cordenonsi, M.6
-
20
-
-
0029915066
-
Towards prediction of cognate complexes between the WW domain and proline-rich ligands
-
Einbond, A., and Sudol, M. (1996). Towards prediction of cognate complexes between the WW domain and proline-rich ligands. FEBS Lett. 384, 1-8.
-
(1996)
FEBS Lett.
, vol.384
, pp. 1-8
-
-
Einbond, A.1
Sudol, M.2
-
21
-
-
38049103263
-
Fat and expanded act in parallel to regulate growth through Warts
-
Feng, Y., and Irvine, K. D. (2007). Fat and expanded act in parallel to regulate growth through Warts. Proc. Natl. Acad. Sci. U.S.A. 104, 20362-20367.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 20362-20367
-
-
Feng, Y.1
Irvine, K.D.2
-
22
-
-
67749093511
-
Processing and phosphorylation of the Fat receptor
-
Feng, Y., and Irvine, K. D. (2009). Processing and phosphorylation of the Fat receptor. Proc. Natl. Acad. Sci. U.S.A. 106, 11989-11994.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 11989-11994
-
-
Feng, Y.1
Irvine, K.D.2
-
23
-
-
84866433774
-
Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene
-
Gaffney, C. J., Oka, T., Mazack, V., Hilman, D., Gat, U., Muramatsu, T., et al. (2012). Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene. Gene 509, 215-222.
-
(2012)
Gene
, vol.509
, pp. 215-222
-
-
Gaffney, C.J.1
Oka, T.2
Mazack, V.3
Hilman, D.4
Gat, U.5
Muramatsu, T.6
-
24
-
-
69649091710
-
The Hippo pathway regulates apical-domain size independently of its growth-control function
-
Genevet, A., Polesello, C., Blight, K., Robertson, F., Collinson, L. M., Pichaud, F., et al. (2009). The Hippo pathway regulates apical-domain size independently of its growth-control function. J. Cell. Sci. 122, 2360-2370.
-
(2009)
J. Cell. Sci.
, vol.122
, pp. 2360-2370
-
-
Genevet, A.1
Polesello, C.2
Blight, K.3
Robertson, F.4
Collinson, L.M.5
Pichaud, F.6
-
25
-
-
76249093838
-
Kibra is a regulator of the Salvador/Warts/Hippo signaling network
-
Genevet, A., Wehr, M. C., Brain, R., Thompson, B. J., and Tapon, N. (2010). Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev. Cell 18, 300-308.
-
(2010)
Dev. Cell
, vol.18
, pp. 300-308
-
-
Genevet, A.1
Wehr, M.C.2
Brain, R.3
Thompson, B.J.4
Tapon, N.5
-
26
-
-
40849086201
-
SCALLOPED interacts with YORKIE, the nuclear effector of the Hippo tumor-suppressor pathway in Drosophila
-
Goulev, Y., Fauny, J. D., Gonzalez-Marti, B., Flagiello, D., Silber, J., and Zider, A. (2008). SCALLOPED interacts with YORKIE, the nuclear effector of the Hippo tumor-suppressor pathway in Drosophila. Curr. Biol. 18, 435-441.
-
(2008)
Curr. Biol.
, vol.18
, pp. 435-441
-
-
Goulev, Y.1
Fauny, J.D.2
Gonzalez-Marti, B.3
Flagiello, D.4
Silber, J.5
Zider, A.6
-
27
-
-
77950485564
-
Lgl, aPKC, and crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms
-
Grzeschik, N. A., Parsons, L. M., Allott, M. L., Harvey, K. F., and Richardson, H. E. (2010). Lgl, aPKC, and crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr. Biol. 20, 573-581.
-
(2010)
Curr. Biol.
, vol.20
, pp. 573-581
-
-
Grzeschik, N.A.1
Parsons, L.M.2
Allott, M.L.3
Harvey, K.F.4
Richardson, H.E.5
-
28
-
-
1342291118
-
Loss of the tumor suppressor PML in human cancers of multiple histologic origins
-
Gurrieri, C., Capodieci, P., Bernardi, R., Scaglioni, P. P., Nafa, K., Rush, L. J., et al. (2004a). Loss of the tumor suppressor PML in human cancers of multiple histologic origins. J. Natl. Cancer Inst. 96, 269-279.
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 269-279
-
-
Gurrieri, C.1
Capodieci, P.2
Bernardi, R.3
Scaglioni, P.P.4
Nafa, K.5
Rush, L.J.6
-
29
-
-
12144286886
-
Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia
-
Gurrieri, C., Nafa, K., Merghoub, T., Bernardi, R., Capodieci, P., Biondi, A., et al. (2004b). Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia. Blood 103, 2358-2362.
-
(2004)
Blood
, vol.103
, pp. 2358-2362
-
-
Gurrieri, C.1
Nafa, K.2
Merghoub, T.3
Bernardi, R.4
Capodieci, P.5
Biondi, A.6
-
30
-
-
84865411430
-
Transduction of mechanical and cytoskeletal cues by YAP and TAZ
-
Halder, G., Dupont, S., and Piccolo, S. (2012). Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat. Rev. Mol. Cell Biol. 13, 591-600.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 591-600
-
-
Halder, G.1
Dupont, S.2
Piccolo, S.3
-
31
-
-
30344445706
-
The tumour-suppressor genes NF2/Merlin and expanded act through Hippo signalling to regulate cell proliferation and apoptosis
-
Hamaratoglu, F., Willecke, M., Kango-Singh, M., Nolo, R., Hyun, E., Tao, C., et al. (2006). The tumour-suppressor genes NF2/Merlin and expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat. Cell Biol. 8, 27-36.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 27-36
-
-
Hamaratoglu, F.1
Willecke, M.2
Kango-Singh, M.3
Nolo, R.4
Hyun, E.5
Tao, C.6
-
32
-
-
41949138130
-
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
-
Hao, Y., Chun, A., Cheung, K., Rashidi, B., and Yang, X. (2008). Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J. Biol. Chem. 283, 5496-5509.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5496-5509
-
-
Hao, Y.1
Chun, A.2
Cheung, K.3
Rashidi, B.4
Yang, X.5
-
33
-
-
33847206401
-
The Salvador-Warts-Hippo pathway-an emerging tumour-suppressor network
-
Harvey, K., and Tapon, N. (2007). The Salvador-Warts-Hippo pathway-an emerging tumour-suppressor network. Nat. Rev. Cancer 7, 182-191.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 182-191
-
-
Harvey, K.1
Tapon, N.2
-
34
-
-
66349134417
-
Promyelocytic leukemia protein is required for gain of function by mutant p53
-
Haupt, S., Di Agostino, S., Mizrahi, I., Alsheich-Bartok, O., Voorhoeve, M., Damalas, A., et al. (2009). Promyelocytic leukemia protein is required for gain of function by mutant p53. Cancer Res. 69, 4818-4826.
-
(2009)
Cancer Res.
, vol.69
, pp. 4818-4826
-
-
Haupt, S.1
Di Agostino, S.2
Mizrahi, I.3
Alsheich-Bartok, O.4
Voorhoeve, M.5
Damalas, A.6
-
35
-
-
23744458034
-
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP
-
Huang, J., Wu, S., Barrera, J., Matthews, K., and Pan, D. (2005). The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP. Cell 122, 421-434.
-
(2005)
Cell
, vol.122
, pp. 421-434
-
-
Huang, J.1
Wu, S.2
Barrera, J.3
Matthews, K.4
Pan, D.5
-
36
-
-
47749093500
-
Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains
-
Ishikawa, H. O., Takeuchi, H., Haltiwanger, R. S., and Irvine, K. D. (2008). Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains. Science 321, 401-404.
-
(2008)
Science
, vol.321
, pp. 401-404
-
-
Ishikawa, H.O.1
Takeuchi, H.2
Haltiwanger, R.S.3
Irvine, K.D.4
-
37
-
-
0028902594
-
The Drosophila tumor suppressor gene Warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
-
Justice, R. W., Zilian, O., Woods, D. F., Noll, M., and Bryant, P. J. (1995). The Drosophila tumor suppressor gene Warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev. 9, 534-546.
-
(1995)
Genes Dev.
, vol.9
, pp. 534-546
-
-
Justice, R.W.1
Zilian, O.2
Woods, D.F.3
Noll, M.4
Bryant, P.J.5
-
38
-
-
17744380191
-
TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
-
Kanai, F., Marignani, P. A., Sarbassova, D., Yagi, R., Hall, R. A., Donowitz, M., et al. (2000). TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. EMBO J. 19, 6778-6791.
-
(2000)
EMBO J.
, vol.19
, pp. 6778-6791
-
-
Kanai, F.1
Marignani, P.A.2
Sarbassova, D.3
Yagi, R.4
Hall, R.A.5
Donowitz, M.6
-
39
-
-
0042858208
-
WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
-
Komuro, A., Nagai, M., Navin, N. E., and Sudol, M. (2003). WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J. Biol. Chem. 278, 33334-33341.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33334-33341
-
-
Komuro, A.1
Nagai, M.2
Navin, N.E.3
Sudol, M.4
-
40
-
-
79953310106
-
Taxol resistance in breast cancer cells is mediated by the Hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF
-
Lai, D., Ho, K. C., Hao, Y., and Yang, X. (2011). Taxol resistance in breast cancer cells is mediated by the Hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Res. 71, 2728-2738.
-
(2011)
Cancer Res.
, vol.71
, pp. 2728-2738
-
-
Lai, D.1
Ho, K.C.2
Hao, Y.3
Yang, X.4
-
41
-
-
14844297327
-
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
-
Lai, Z. C., Wei, X., Shimizu, T., Ramos, E., Rohrbaugh, M., Nikolaidis, N., et al. (2005). Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 120, 675-685.
-
(2005)
Cell
, vol.120
, pp. 675-685
-
-
Lai, Z.C.1
Wei, X.2
Shimizu, T.3
Ramos, E.4
Rohrbaugh, M.5
Nikolaidis, N.6
-
42
-
-
0032578033
-
Structural analysis of Drosophila Merlin reveals functional domains important for growth control and subcellular localization
-
LaJeunesse, D. R., McCartney, B. M., and Fehon, R. G. (1998). Structural analysis of Drosophila Merlin reveals functional domains important for growth control and subcellular localization. J. Cell Biol. 141, 1589-1599.
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1589-1599
-
-
LaJeunesse, D.R.1
McCartney, B.M.2
Fehon, R.G.3
-
43
-
-
57749084642
-
PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop
-
Lapi, E., Di Agostino, S., Donzelli, S., Gal, H., Domany, E., Rechavi, G., et al. (2008). PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Mol. Cell 32, 803-814.
-
(2008)
Mol. Cell
, vol.32
, pp. 803-814
-
-
Lapi, E.1
Di Agostino, S.2
Donzelli, S.3
Gal, H.4
Domany, E.5
Rechavi, G.6
-
44
-
-
41149098966
-
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the Hippo pathway
-
Lei, Q. Y., Zhang, H., Zhao, B., Zha, Z. Y., Bai, F., Pei, X. H., et al. (2008). TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the Hippo pathway. Mol. Cell. Biol. 28, 2426-2436.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 2426-2436
-
-
Lei, Q.Y.1
Zhang, H.2
Zhao, B.3
Zha, Z.Y.4
Bai, F.5
Pei, X.H.6
-
45
-
-
33947382284
-
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73
-
Levy, D., Adamovich, Y., Reuven, N., and Shaul, Y. (2007). The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. Cell Death Differ. 14, 743-751.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 743-751
-
-
Levy, D.1
Adamovich, Y.2
Reuven, N.3
Shaul, Y.4
-
46
-
-
55549085229
-
A regulatory circuit controlling Itch-mediated p73 degradation by Runx
-
Levy, D., Reuven, N., and Shaul, Y. (2008). A regulatory circuit controlling Itch-mediated p73 degradation by Runx. J. Biol. Chem. 283, 27462-27468.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27462-27468
-
-
Levy, D.1
Reuven, N.2
Shaul, Y.3
-
47
-
-
0041302154
-
Lats2, a putative tumor suppressor, inhibits G1/S transition
-
Li, Y., Pei, J., Xia, H., Ke, H., Wang, H., and Tao, W. (2003). Lats2, a putative tumor suppressor, inhibits G1/S transition. Oncogene 22, 4398-4405.
-
(2003)
Oncogene
, vol.22
, pp. 4398-4405
-
-
Li, Y.1
Pei, J.2
Xia, H.3
Ke, H.4
Wang, H.5
Tao, W.6
-
48
-
-
77953040994
-
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation
-
Lian, I., Kim, J., Okazawa, H., Zhao, J., Zhao, B., Yu, J., et al. (2010). The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev. 24, 1106-1118.
-
(2010)
Genes Dev.
, vol.24
, pp. 1106-1118
-
-
Lian, I.1
Kim, J.2
Okazawa, H.3
Zhao, J.4
Zhao, B.5
Yu, J.6
-
49
-
-
0037073794
-
Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis
-
Lin, Y., Khokhlatchev, A., Figeys, D., and Avruch, J. (2002). Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis. J. Biol. Chem. 277, 47991-48001.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47991-48001
-
-
Lin, Y.1
Khokhlatchev, A.2
Figeys, D.3
Avruch, J.4
-
50
-
-
77953738883
-
The apical transmembrane protein crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
-
Ling, C., Zheng, Y., Yin, F., Yu, J., Huang, J., Hong, Y., et al. (2010). The apical transmembrane protein crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc. Natl. Acad. Sci. U.S.A. 107, 10532-10537.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 10532-10537
-
-
Ling, C.1
Zheng, Y.2
Yin, F.3
Yu, J.4
Huang, J.5
Hong, Y.6
-
51
-
-
84862605178
-
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
-
Liu-Chittenden, Y., Huang, B., Shim, J. S., Chen, Q., Lee, S. J., Anders, R. A., et al. (2012). Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev. 26, 1300-1305.
-
(2012)
Genes Dev.
, vol.26
, pp. 1300-1305
-
-
Liu-Chittenden, Y.1
Huang, B.2
Shim, J.S.3
Chen, Q.4
Lee, S.J.5
Anders, R.A.6
-
52
-
-
0025748166
-
The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily
-
Mahoney, P. A., Weber, U., Onofrechuk, P., Biessmann, H., Bryant, P. J., and Goodman, C. S. (1991). The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily. Cell 67, 853-868.
-
(1991)
Cell
, vol.67
, pp. 853-868
-
-
Mahoney, P.A.1
Weber, U.2
Onofrechuk, P.3
Biessmann, H.4
Bryant, P.J.5
Goodman, C.S.6
-
53
-
-
19544393341
-
The transcriptional co-activator TAZ interacts differentially with transcriptional enhancer factor-1 (TEF-1) family members
-
Mahoney, W. M. Jr., Hong, J. H., Yaffe, M. B., and Farrance, I. K. (2005). The transcriptional co-activator TAZ interacts differentially with transcriptional enhancer factor-1 (TEF-1) family members. Biochem. J. 388, 217-225.
-
(2005)
Biochem. J.
, vol.388
, pp. 217-225
-
-
Mahoney Jr., W.M.1
Hong, J.H.2
Yaffe, M.B.3
Farrance, I.K.4
-
54
-
-
4444240972
-
Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing
-
Matakatsu, H., and Blair, S. S. (2004). Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing. Development 131, 3785-3794.
-
(2004)
Development
, vol.131
, pp. 3785-3794
-
-
Matakatsu, H.1
Blair, S.S.2
-
55
-
-
33745899356
-
Separating the adhesive and signaling functions of the fat and dachsous protocadherins
-
Matakatsu, H., and Blair, S. S. (2006). Separating the adhesive and signaling functions of the fat and dachsous protocadherins. Development 133, 2315-2324.
-
(2006)
Development
, vol.133
, pp. 2315-2324
-
-
Matakatsu, H.1
Blair, S.S.2
-
56
-
-
34748812613
-
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein
-
Matallanas, D., Romano, D., Yee, K., Meissl, K., Kucerova, L., Piazzolla, D., et al. (2007). RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein. Mol. Cell 27, 962-975.
-
(2007)
Mol. Cell
, vol.27
, pp. 962-975
-
-
Matallanas, D.1
Romano, D.2
Yee, K.3
Meissl, K.4
Kucerova, L.5
Piazzolla, D.6
-
57
-
-
84859583470
-
Integrating developmental signals: a Hippo in the (path)way
-
Mauviel, A., Nallet-Staub, F., and Varelas, X. (2012). Integrating developmental signals: a Hippo in the (path)way. Oncogene 31, 1743-1756.
-
(2012)
Oncogene
, vol.31
, pp. 1743-1756
-
-
Mauviel, A.1
Nallet-Staub, F.2
Varelas, X.3
-
58
-
-
80155137594
-
Master transcription factors determine cell-type-specific responses to TGF-beta signaling
-
Mullen, A. C., Orlando, D. A., Newman, J. J., Loven, J., Kumar, R. M., Bilodeau, S., et al. (2011). Master transcription factors determine cell-type-specific responses to TGF-beta signaling. Cell 147, 565-576.
-
(2011)
Cell
, vol.147
, pp. 565-576
-
-
Mullen, A.C.1
Orlando, D.A.2
Newman, J.J.3
Loven, J.4
Kumar, R.M.5
Bilodeau, S.6
-
59
-
-
77957881882
-
Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap
-
Neto-Silva, R. M., De Beco, S., and Johnston, L. A. (2010). Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap. Dev. Cell 19, 507-520.
-
(2010)
Dev. Cell
, vol.19
, pp. 507-520
-
-
Neto-Silva, R.M.1
De Beco, S.2
Johnston, L.A.3
-
60
-
-
42549092233
-
In vivo regulation of Yorkie phosphorylation and localization
-
Oh, H., and Irvine, K. D. (2008). In vivo regulation of Yorkie phosphorylation and localization. Development 135, 1081-1088.
-
(2008)
Development
, vol.135
, pp. 1081-1088
-
-
Oh, H.1
Irvine, K.D.2
-
61
-
-
70349786516
-
Phosphorylation-independent repression of Yorkie in fat-Hippo signaling
-
Oh, H., Reddy, B. V., and Irvine, K. D. (2009). Phosphorylation-independent repression of Yorkie in fat-Hippo signaling. Dev. Biol. 335, 188-197.
-
(2009)
Dev. Biol.
, vol.335
, pp. 188-197
-
-
Oh, H.1
Reddy, B.V.2
Irvine, K.D.3
-
62
-
-
55549098921
-
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
-
Oka, T., Mazack, V., and Sudol, M. (2008). Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J. Biol. Chem. 283, 27534-27546.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27534-27546
-
-
Oka, T.1
Mazack, V.2
Sudol, M.3
-
63
-
-
78649892579
-
Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling
-
Oka, T., Remue, E., Meerschaert, K., Vanloo, B., Boucherie, C., Gfeller, D., et al. (2010). Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling. Biochem. J. 432, 461-472.
-
(2010)
Biochem. J.
, vol.432
, pp. 461-472
-
-
Oka, T.1
Remue, E.2
Meerschaert, K.3
Vanloo, B.4
Boucherie, C.5
Gfeller, D.6
-
64
-
-
84855344741
-
Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAP
-
Oka, T., Schmitt, A. P., and Sudol, M. (2012). Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAP. Oncogene 31, 128-134.
-
(2012)
Oncogene
, vol.31
, pp. 128-134
-
-
Oka, T.1
Schmitt, A.P.2
Sudol, M.3
-
65
-
-
65449154339
-
Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZ-binding motif
-
Oka, T., and Sudol, M. (2009). Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZ-binding motif. Genes Cells 14, 607-615.
-
(2009)
Genes Cells
, vol.14
, pp. 607-615
-
-
Oka, T.1
Sudol, M.2
-
66
-
-
84863084587
-
Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma
-
Okazaki, T., Kageji, T., Kuwayama, K., Kitazato, K. T., Mure, H., Hara, K., et al. (2012). Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma. Cancer Lett. 323, 199-207.
-
(2012)
Cancer Lett.
, vol.323
, pp. 199-207
-
-
Okazaki, T.1
Kageji, T.2
Kuwayama, K.3
Kitazato, K.T.4
Mure, H.5
Hara, K.6
-
67
-
-
11144267126
-
Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1
-
O'Neill, E., Rushworth, L., Baccarini, M., and Kolch, W. (2004). Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1. Science 306, 2267-2270.
-
(2004)
Science
, vol.306
, pp. 2267-2270
-
-
O'Neill, E.1
Rushworth, L.2
Baccarini, M.3
Kolch, W.4
-
68
-
-
0034644274
-
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
-
Pearson, M., Carbone, R., Sebastiani, C., Cioce, M., Fagioli, M., Saito, S., et al. (2000). PML regulates p53 acetylation and premature senescence induced by oncogenic Ras. Nature 406, 207-210.
-
(2000)
Nature
, vol.406
, pp. 207-210
-
-
Pearson, M.1
Carbone, R.2
Sebastiani, C.3
Cioce, M.4
Fagioli, M.5
Saito, S.6
-
69
-
-
70349624119
-
Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc
-
Peng, H. W., Slattery, M., and Mann, R. S. (2009). Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc. Genes Dev. 23, 2307-2319.
-
(2009)
Genes Dev.
, vol.23
, pp. 2307-2319
-
-
Peng, H.W.1
Slattery, M.2
Mann, R.S.3
-
70
-
-
40149111984
-
MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation
-
Praskova, M., Xia, F., and Avruch, J. (2008). MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation. Curr. Biol. 18, 311-321.
-
(2008)
Curr. Biol.
, vol.18
, pp. 311-321
-
-
Praskova, M.1
Xia, F.2
Avruch, J.3
-
71
-
-
77955988806
-
Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling
-
Ribeiro, P. S., Josue, F., Wepf, A., Wehr, M. C., Rinner, O., Kelly, G., et al. (2010). Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling. Mol. Cell 39, 521-534.
-
(2010)
Mol. Cell
, vol.39
, pp. 521-534
-
-
Ribeiro, P.S.1
Josue, F.2
Wepf, A.3
Wehr, M.C.4
Rinner, O.5
Kelly, G.6
-
72
-
-
77950478873
-
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein expanded
-
Robinson, B. S., Huang, J., Hong, Y., and Moberg, K. H. (2010). Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein expanded. Curr. Biol. 20, 582-590.
-
(2010)
Curr. Biol.
, vol.20
, pp. 582-590
-
-
Robinson, B.S.1
Huang, J.2
Hong, Y.3
Moberg, K.H.4
-
73
-
-
84871576111
-
beta-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis
-
Rosenbluh, J., Nijhawan, D., Cox, A. G., Li, X., Neal, J. T., Schafer, E. J., et al. (2012). beta-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell 151, 1457-1473.
-
(2012)
Cell
, vol.151
, pp. 1457-1473
-
-
Rosenbluh, J.1
Nijhawan, D.2
Cox, A.G.3
Li, X.4
Neal, J.T.5
Schafer, E.J.6
-
74
-
-
15444367709
-
The ubiquitin-protein ligase Itch regulates p73 stability
-
Rossi, M., De Laurenzi, V., Munarriz, E., Green, D. R., Liu, Y. C., Vousden, K. H., et al. (2005). The ubiquitin-protein ligase Itch regulates p73 stability. EMBO J. 24, 836-848.
-
(2005)
EMBO J.
, vol.24
, pp. 836-848
-
-
Rossi, M.1
De Laurenzi, V.2
Munarriz, E.3
Green, D.R.4
Liu, Y.C.5
Vousden, K.H.6
-
75
-
-
0037169341
-
The role of PML in tumor suppression
-
Salomoni, P., and Pandolfi, P. P. (2002). The role of PML in tumor suppression. Cell 108, 165-170.
-
(2002)
Cell
, vol.108
, pp. 165-170
-
-
Salomoni, P.1
Pandolfi, P.P.2
-
76
-
-
43249089639
-
Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival
-
Sawada, A., Kiyonari, H., Ukita, K., Nishioka, N., Imuta, Y., and Sasaki, H. (2008). Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival. Mol. Cell. Biol. 28, 3177-3189.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3177-3189
-
-
Sawada, A.1
Kiyonari, H.2
Ukita, K.3
Nishioka, N.4
Imuta, Y.5
Sasaki, H.6
-
77
-
-
84863456310
-
Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence
-
Scaglioni, P. P., Rabellino, A., Yung, T. M., Bernardi, R., Choi, S., Konstantinidou, G., et al. (2012). Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence. EMBO Mol. Med. 4, 594-602.
-
(2012)
EMBO Mol. Med.
, vol.4
, pp. 594-602
-
-
Scaglioni, P.P.1
Rabellino, A.2
Yung, T.M.3
Bernardi, R.4
Choi, S.5
Konstantinidou, G.6
-
78
-
-
33750447586
-
The mechanisms of PML-nuclear body formation
-
Shen, T. H., Lin, H. K., Scaglioni, P. P., Yung, T. M., and Pandolfi, P. P. (2006). The mechanisms of PML-nuclear body formation. Mol. Cell 24, 331-339.
-
(2006)
Mol. Cell
, vol.24
, pp. 331-339
-
-
Shen, T.H.1
Lin, H.K.2
Scaglioni, P.P.3
Yung, T.M.4
Pandolfi, P.P.5
-
79
-
-
0032907439
-
Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
-
St John, M. A., Tao, W., Fei, X., Fukumoto, R., Carcangiu, M. L., Brownstein, D. G., et al. (1999). Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction. Nat. Genet. 21, 182-186.
-
(1999)
Nat. Genet.
, vol.21
, pp. 182-186
-
-
St John, M.A.1
Tao, W.2
Fei, X.3
Fukumoto, R.4
Carcangiu, M.L.5
Brownstein, D.G.6
-
80
-
-
21044442524
-
The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage
-
Strano, S., Monti, O., Pediconi, N., Baccarini, A., Fontemaggi, G., Lapi, E., et al. (2005). The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage. Mol. Cell 18, 447-459.
-
(2005)
Mol. Cell
, vol.18
, pp. 447-459
-
-
Strano, S.1
Monti, O.2
Pediconi, N.3
Baccarini, A.4
Fontemaggi, G.5
Lapi, E.6
-
81
-
-
0035805487
-
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
-
Strano, S., Munarriz, E., Rossi, M., Castagnoli, L., Shaul, Y., Sacchi, A., et al. (2001). Physical interaction with Yes-associated protein enhances p73 transcriptional activity. J. Biol. Chem. 276, 15164-15173.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 15164-15173
-
-
Strano, S.1
Munarriz, E.2
Rossi, M.3
Castagnoli, L.4
Shaul, Y.5
Sacchi, A.6
-
82
-
-
0028283579
-
Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product
-
Sudol, M. (1994). Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product. Oncogene 9, 2145-2152.
-
(1994)
Oncogene
, vol.9
, pp. 2145-2152
-
-
Sudol, M.1
-
83
-
-
79959962948
-
Newcomers to the WW domain-mediated network of the Hippo tumor suppressor pathway
-
Sudol, M. (2010). Newcomers to the WW domain-mediated network of the Hippo tumor suppressor pathway. Genes Cancer 1, 1115-1118.
-
(2010)
Genes Cancer
, vol.1
, pp. 1115-1118
-
-
Sudol, M.1
-
84
-
-
84867359654
-
WW Domains in the heart of smad regulation
-
Sudol, M. (2012). WW Domains in the heart of smad regulation. Structure 20, 1619-1620.
-
(2012)
Structure
, vol.20
, pp. 1619-1620
-
-
Sudol, M.1
-
85
-
-
0028997651
-
Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain
-
Sudol, M., Bork, P., Einbond, A., Kastury, K., Druck, T., Negrini, M., et al. (1995). Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain. J. Biol. Chem. 270, 14733-14741.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14733-14741
-
-
Sudol, M.1
Bork, P.2
Einbond, A.3
Kastury, K.4
Druck, T.5
Negrini, M.6
-
86
-
-
78049290801
-
Modularity in the Hippo signaling pathway
-
Sudol, M., and Harvey, K. F. (2010). Modularity in the Hippo signaling pathway. Trends Biochem. Sci. 35, 627-633.
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 627-633
-
-
Sudol, M.1
Harvey, K.F.2
-
87
-
-
0034704216
-
NeW wrinkles for an old domain
-
Sudol, M., and Hunter, T. (2000). NeW wrinkles for an old domain. Cell 103, 1001-1004.
-
(2000)
Cell
, vol.103
, pp. 1001-1004
-
-
Sudol, M.1
Hunter, T.2
-
88
-
-
84866634953
-
Structures of YAP protein domains reveal promising targets for development of new cancer drugs
-
Sudol, M., Shields, D. C., and Farooq, A. (2012). Structures of YAP protein domains reveal promising targets for development of new cancer drugs. Semin. Cell Dev. Biol. 23, 827-833.
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 827-833
-
-
Sudol, M.1
Shields, D.C.2
Farooq, A.3
-
89
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K., and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
90
-
-
0037162714
-
Salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
-
Tapon, N., Harvey, K. F., Bell, D. W., Wahrer, D. C., Schiripo, T. A., Haber, D. A., et al. (2002). Salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110, 467-478.
-
(2002)
Cell
, vol.110
, pp. 467-478
-
-
Tapon, N.1
Harvey, K.F.2
Bell, D.W.3
Wahrer, D.C.4
Schiripo, T.A.5
Haber, D.A.6
-
91
-
-
33745316089
-
Identification of a tumour suppressor network opposing nuclear Akt function
-
Trotman, L. C., Alimonti, A., Scaglioni, P. P., Koutcher, J. A., Cordon-Cardo, C., and Pandolfi, P. P. (2006). Identification of a tumour suppressor network opposing nuclear Akt function. Nature 441, 523-527.
-
(2006)
Nature
, vol.441
, pp. 523-527
-
-
Trotman, L.C.1
Alimonti, A.2
Scaglioni, P.P.3
Koutcher, J.A.4
Cordon-Cardo, C.5
Pandolfi, P.P.6
-
92
-
-
34547161916
-
Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis
-
Ura, S., Nishina, H., Gotoh, Y., and Katada, T. (2007). Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis. Mol. Cell. Biol. 27, 5514-5522.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 5514-5522
-
-
Ura, S.1
Nishina, H.2
Gotoh, Y.3
Katada, T.4
-
93
-
-
46049087598
-
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
-
Varelas, X., Sakuma, R., Samavarchi-Tehrani, P., Peerani, R., Rao, B. M., Dembowy, J., et al. (2008). TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat. Cell Biol. 10, 837-848.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 837-848
-
-
Varelas, X.1
Sakuma, R.2
Samavarchi-Tehrani, P.3
Peerani, R.4
Rao, B.M.5
Dembowy, J.6
-
94
-
-
78649969033
-
The crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway
-
Varelas, X., Samavarchi-Tehrani, P., Narimatsu, M., Weiss, A., Cockburn, K., Larsen, B. G., et al. (2010). The crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway. Dev. Cell 19, 831-844.
-
(2010)
Dev. Cell
, vol.19
, pp. 831-844
-
-
Varelas, X.1
Samavarchi-Tehrani, P.2
Narimatsu, M.3
Weiss, A.4
Cockburn, K.5
Larsen, B.G.6
-
95
-
-
0035873391
-
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
-
Vassilev, A., Kaneko, K. J., Shu, H., Zhao, Y., and Depamphilis, M. L. (2001). TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm. Genes Dev. 15, 1229-1241.
-
(2001)
Genes Dev.
, vol.15
, pp. 1229-1241
-
-
Vassilev, A.1
Kaneko, K.J.2
Shu, H.3
Zhao, Y.4
Depamphilis, M.L.5
-
96
-
-
0036674617
-
Live or let die: the cell's response to p53
-
Vousden, K. H., and Lu, X. (2002). Live or let die: the cell's response to p53. Nat. Rev. Cancer 2, 594-604.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
97
-
-
79953010044
-
Angiomotin-like proteins associate with and negatively regulate YAP1
-
Wang, W., Huang, J., and Chen, J. (2011). Angiomotin-like proteins associate with and negatively regulate YAP1. J. Biol. Chem. 286, 4364-4370.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 4364-4370
-
-
Wang, W.1
Huang, J.2
Chen, J.3
-
98
-
-
0000237552
-
Role of PML in cell growth and the retinoic acid pathway
-
Wang, Z. G., Delva, L., Gaboli, M., Rivi, R., Giorgio, M., Cordon-Cardo, C., et al. (1998). Role of PML in cell growth and the retinoic acid pathway. Science 279, 1547-1551.
-
(1998)
Science
, vol.279
, pp. 1547-1551
-
-
Wang, Z.G.1
Delva, L.2
Gaboli, M.3
Rivi, R.4
Giorgio, M.5
Cordon-Cardo, C.6
-
99
-
-
0035868643
-
Inhibition of touch cell fate by egl-44 and egl-46 in C
-
Wu, J., Duggan, A., and Chalfie, M. (2001). Inhibition of touch cell fate by egl-44 and egl-46 in C. elegans. Genes Dev. 15, 789-802.
-
(2001)
elegans. Genes Dev.
, vol.15
, pp. 789-802
-
-
Wu, J.1
Duggan, A.2
Chalfie, M.3
-
100
-
-
0042232429
-
Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with Salvador and Warts
-
Wu, S., Huang, J., Dong, J., and Pan, D. (2003). Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with Salvador and Warts. Cell 114, 445-456.
-
(2003)
Cell
, vol.114
, pp. 445-456
-
-
Wu, S.1
Huang, J.2
Dong, J.3
Pan, D.4
-
101
-
-
42049116586
-
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
-
Wu, S., Liu, Y., Zheng, Y., Dong, J., and Pan, D. (2008). The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev. Cell 14, 388-398.
-
(2008)
Dev. Cell
, vol.14
, pp. 388-398
-
-
Wu, S.1
Liu, Y.2
Zheng, Y.3
Dong, J.4
Pan, D.5
-
102
-
-
85047699404
-
LATS1 tumor suppressor regulates G2/M transition and apoptosis
-
Xia, H., Qi, H., Li, Y., Pei, J., Barton, J., Blackstad, M., et al. (2002). LATS1 tumor suppressor regulates G2/M transition and apoptosis. Oncogene 21, 1233-1241.
-
(2002)
Oncogene
, vol.21
, pp. 1233-1241
-
-
Xia, H.1
Qi, H.2
Li, Y.3
Pei, J.4
Barton, J.5
Blackstad, M.6
-
103
-
-
34547103279
-
Lats2 is an essential mitotic regulator required for the coordination of cell division
-
Yabuta, N., Okada, N., Ito, A., Hosomi, T., Nishihara, S., Sasayama, Y., et al. (2007). Lats2 is an essential mitotic regulator required for the coordination of cell division. J. Biol. Chem. 282, 19259-19271.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 19259-19271
-
-
Yabuta, N.1
Okada, N.2
Ito, A.3
Hosomi, T.4
Nishihara, S.5
Sasayama, Y.6
-
104
-
-
0033522472
-
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
-
Yagi, R., Chen, L. F., Shigesada, K., Murakami, Y., and Ito, Y. (1999). A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J. 18, 2551-2562.
-
(1999)
EMBO J.
, vol.18
, pp. 2551-2562
-
-
Yagi, R.1
Chen, L.F.2
Shigesada, K.3
Murakami, Y.4
Ito, Y.5
-
105
-
-
0035807242
-
Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G(2)/M arrest or apoptosis
-
Yang, X., Li, D. M., Chen, W., and Xu, T. (2001). Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G(2)/M arrest or apoptosis. Oncogene 20, 6516-6523.
-
(2001)
Oncogene
, vol.20
, pp. 6516-6523
-
-
Yang, X.1
Li, D.M.2
Chen, W.3
Xu, T.4
-
106
-
-
76249109900
-
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
-
Yu, J., Zheng, Y., Dong, J., Klusza, S., Deng, W. M., and Pan, D. (2010). Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev. Cell 18, 288-299.
-
(2010)
Dev. Cell
, vol.18
, pp. 288-299
-
-
Yu, J.1
Zheng, Y.2
Dong, J.3
Klusza, S.4
Deng, W.M.5
Pan, D.6
-
107
-
-
54049121368
-
Yes-associated protein (YAP) functions as a tumor suppressor in breast
-
Yuan, M., Tomlinson, V., Lara, R., Holliday, D., Chelala, C., Harada, T., et al. (2008). Yes-associated protein (YAP) functions as a tumor suppressor in breast. Cell Death Differ. 15, 1752-1759.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 1752-1759
-
-
Yuan, M.1
Tomlinson, V.2
Lara, R.3
Holliday, D.4
Chelala, C.5
Harada, T.6
-
108
-
-
1842457741
-
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
-
Zaidi, S. K., Sullivan, A. J., Medina, R., Ito, Y., Van Wijnen, A. J., Stein, J. L., et al. (2004). Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J. 23, 790-799.
-
(2004)
EMBO J.
, vol.23
, pp. 790-799
-
-
Zaidi, S.K.1
Sullivan, A.J.2
Medina, R.3
Ito, Y.4
Van Wijnen, A.J.5
Stein, J.L.6
-
109
-
-
42049120338
-
The TEAD/TEF family of transcription factor scalloped mediates Hippo signaling in organ size control
-
Zhang, L., Ren, F., Zhang, Q., Chen, Y., Wang, B., and Jiang, J. (2008). The TEAD/TEF family of transcription factor scalloped mediates Hippo signaling in organ size control. Dev. Cell 14, 377-387.
-
(2008)
Dev. Cell
, vol.14
, pp. 377-387
-
-
Zhang, L.1
Ren, F.2
Zhang, Q.3
Chen, Y.4
Wang, B.5
Jiang, J.6
-
110
-
-
59149088576
-
Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein
-
Zhao, B., Kim, J., Ye, X., Lai, Z. C., and Guan, K. L. (2009). Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein. Cancer Res. 69, 1089-1098.
-
(2009)
Cancer Res.
, vol.69
, pp. 1089-1098
-
-
Zhao, B.1
Kim, J.2
Ye, X.3
Lai, Z.C.4
Guan, K.L.5
-
111
-
-
78650895035
-
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
-
Zhao, B., Li, L., Lu, Q., Wang, L. H., Liu, C. Y., Lei, Q., et al. (2011). Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev. 25, 51-63.
-
(2011)
Genes Dev.
, vol.25
, pp. 51-63
-
-
Zhao, B.1
Li, L.2
Lu, Q.3
Wang, L.H.4
Liu, C.Y.5
Lei, Q.6
-
112
-
-
73549095761
-
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
-
Zhao, B., Li, L., Tumaneng, K., Wang, C. Y., and Guan, K. L. (2010). A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev. 24, 72-85.
-
(2010)
Genes Dev.
, vol.24
, pp. 72-85
-
-
Zhao, B.1
Li, L.2
Tumaneng, K.3
Wang, C.Y.4
Guan, K.L.5
-
113
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
Zhao, B., Wei, X., Li, W., Udan, R. S., Yang, Q., Kim, J., et al. (2007). Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev. 21, 2747-2761.
-
(2007)
Genes Dev.
, vol.21
, pp. 2747-2761
-
-
Zhao, B.1
Wei, X.2
Li, W.3
Udan, R.S.4
Yang, Q.5
Kim, J.6
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