-
1
-
-
33947380185
-
Regulation of intestinal cholesterol absorption
-
Wang DQ. Regulation of intestinal cholesterol absorption. Annu Rev Physiol 2007;69:221-48.
-
(2007)
Annu Rev Physiol
, vol.69
, pp. 221-248
-
-
Wang, D.Q.1
-
2
-
-
84862775399
-
-
U.S. Department of Agriculture and U.S. Department Health and Human Services. Gardiner, Maine: Northern House Media
-
U.S. Department of Agriculture and U.S. Department Health and Human Services. Dietary Guidelines for Americans. Gardiner, Maine: Northern House Media, 2011, pp. 1-95.
-
(2011)
Dietary Guidelines for Americans
, pp. 1-95
-
-
-
5
-
-
0018765360
-
Watching fat digestion
-
Patton JS, Carey MC. Watching fat digestion. Science 1979;204:145-8.
-
(1979)
Science
, vol.204
, pp. 145-148
-
-
Patton, J.S.1
Carey, M.C.2
-
6
-
-
0037040172
-
Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine: a process mediated via ceramide hydrolysis
-
Kirby RJ, Zheng S, Tso P, Howles PN, Hui DY. Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine: a process mediated via ceramide hydrolysis. J Biol Chem 2002;277:4104-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 4104-4109
-
-
Kirby, R.J.1
Zheng, S.2
Tso, P.3
Howles, P.N.4
Hui, D.Y.5
-
7
-
-
0033616639
-
Intestinal absorption of dietary cholesteryl ester is decreased but retinyl ester absorption is normal in carboxyl ester lipase knockout mice
-
Weng W, Li L, van Bennekum AM, Potter SH, Harrison EH, Blaner WS et al. Intestinal absorption of dietary cholesteryl ester is decreased but retinyl ester absorption is normal in carboxyl ester lipase knockout mice. Biochemistry 1999;38:4143-9.
-
(1999)
Biochemistry
, vol.38
, pp. 4143-4149
-
-
Weng, W.1
Li, L.2
van Bennekum, A.M.3
Potter, S.H.4
Harrison, E.H.5
Blaner, W.S.6
-
8
-
-
0018877342
-
Studies on the substrate specificity of a carboxyl ester hydrolase from human pancreatic juice. I. Action on carboxyl esters, glycerides and phospholipids
-
Lombardo D, Fauvel J, Guy O. Studies on the substrate specificity of a carboxyl ester hydrolase from human pancreatic juice. I. Action on carboxyl esters, glycerides and phospholipids. Biochim Biophys Acta 1980;611:136-46.
-
(1980)
Biochim Biophys Acta
, vol.611
, pp. 136-146
-
-
Lombardo, D.1
Fauvel, J.2
Guy, O.3
-
9
-
-
0019831849
-
Binding of human pancreatic carboxylic ester hydrolase to lipid interfaces
-
Lombardo D, Guy O. Binding of human pancreatic carboxylic ester hydrolase to lipid interfaces. Biochim Biophys Acta 1981;659:401-10.
-
(1981)
Biochim Biophys Acta
, vol.659
, pp. 401-410
-
-
Lombardo, D.1
Guy, O.2
-
10
-
-
0025239461
-
Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings
-
Staggers JE, Hernell O, Stafford RJ, Carey MC. Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings. Biochemistry 1990;29:2028-40.
-
(1990)
Biochemistry
, vol.29
, pp. 2028-2040
-
-
Staggers, J.E.1
Hernell, O.2
Stafford, R.J.3
Carey, M.C.4
-
11
-
-
0025264030
-
Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings
-
Hernell O, Staggers JE, Carey MC. Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings. Biochemistry 1990;29:2041-56.
-
(1990)
Biochemistry
, vol.29
, pp. 2041-2056
-
-
Hernell, O.1
Staggers, J.E.2
Carey, M.C.3
-
12
-
-
0242322024
-
Pancreatic triglyceride lipase deficiency minimally affects dietary fat absorption but dramatically decreases dietary cholesterol absorption in mice
-
Huggins KW, Camarota LM, Howles PN, Hui DY. Pancreatic triglyceride lipase deficiency minimally affects dietary fat absorption but dramatically decreases dietary cholesterol absorption in mice. J Biol Chem 2003;278:42899-905.
-
(2003)
J Biol Chem
, vol.278
, pp. 42899-42905
-
-
Huggins, K.W.1
Camarota, L.M.2
Howles, P.N.3
Hui, D.Y.4
-
13
-
-
0000905362
-
C14-Cholesterol. V. Obligatory function of bile in intestinal absorption of cholesterol
-
Siperstein MD, Chaikoff IL, Reinhardt WO. C14-Cholesterol. V. Obligatory function of bile in intestinal absorption of cholesterol. J Biol Chem 1952;198:111-4.
-
(1952)
J Biol Chem
, vol.198
, pp. 111-114
-
-
Siperstein, M.D.1
Chaikoff, I.L.2
Reinhardt, W.O.3
-
14
-
-
0021840051
-
The micellar hypothesis of fat absorption: must it be revisited?
-
Borgstrom B. The micellar hypothesis of fat absorption: must it be revisited? Scand J Gastroenterol 1985;20:389-94.
-
(1985)
Scand J Gastroenterol
, vol.20
, pp. 389-394
-
-
Borgstrom, B.1
-
15
-
-
0017121838
-
The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell
-
Westergaard H, Dietschy JM. The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell. J Clin Invest 1976;58:97-108.
-
(1976)
J Clin Invest
, vol.58
, pp. 97-108
-
-
Westergaard, H.1
Dietschy, J.M.2
-
16
-
-
0015209610
-
Unstirred water layers in intestine: rate determinant of fatty acid absorption from micellar solutions
-
Wilson FA, Sallee VL, Dietschy JM. Unstirred water layers in intestine: rate determinant of fatty acid absorption from micellar solutions. Science 1971;174:1031-3.
-
(1971)
Science
, vol.174
, pp. 1031-1033
-
-
Wilson, F.A.1
Sallee, V.L.2
Dietschy, J.M.3
-
17
-
-
0041965752
-
Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse
-
Wang DQ, Tazuma S, Cohen DE, Carey MC. Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse. Am J Physiol 2003;285:G494-502.
-
(2003)
Am J Physiol
, vol.285
-
-
Wang, D.Q.1
Tazuma, S.2
Cohen, D.E.3
Carey, M.C.4
-
18
-
-
0032953973
-
Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis
-
Wang DQ, Lammert F, Cohen DE, Paigen B, Carey MC. Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis. Am J Physiol 1999;276:G751-60.
-
(1999)
Am J Physiol
, vol.276
-
-
Wang, D.Q.1
Lammert, F.2
Cohen, D.E.3
Paigen, B.4
Carey, M.C.5
-
19
-
-
4143075784
-
Lack of the intestinal Muc1 mucin impairs cholesterol uptake and absorption but not fatty acid uptake in Muc1-/- mice
-
Wang HH, Afdhal NH, Gendler SJ, Wang DQ. Lack of the intestinal Muc1 mucin impairs cholesterol uptake and absorption but not fatty acid uptake in Muc1-/- mice. Am J Physiol 2004;287:G547-54.
-
(2004)
Am J Physiol
, vol.287
-
-
Wang, H.H.1
Afdhal, N.H.2
Gendler, S.J.3
Wang, D.Q.4
-
20
-
-
0034922738
-
Fatty acid transport: the diffusion mechanism in model and biological membranes
-
discussion 151-107.
-
Hamilton JA, Johnson RA, Corkey B, Kamp F. Fatty acid transport: the diffusion mechanism in model and biological membranes. J Mol Neurosci 2001;16:99-108; discussion 151-107.
-
(2001)
J Mol Neurosci
, vol.16
, pp. 99-108
-
-
Hamilton, J.A.1
Johnson, R.A.2
Corkey, B.3
Kamp, F.4
-
21
-
-
0030048273
-
The effect of intracellular pH on long-chain fatty acid uptake in 3T3-L1 adipocytes: evidence that uptake involves the passive diffusion of protonated long-chain fatty acids across the plasma membrane
-
Trigatti BL, Gerber GE. The effect of intracellular pH on long-chain fatty acid uptake in 3T3-L1 adipocytes: evidence that uptake involves the passive diffusion of protonated long-chain fatty acids across the plasma membrane. Biochem J 1996;313(Pt 2):487-94.
-
(1996)
Biochem J
, vol.313
, Issue.PART 2
, pp. 487-494
-
-
Trigatti, B.L.1
Gerber, G.E.2
-
22
-
-
0036693935
-
How fatty acids bind to proteins: the inside story from protein structures
-
Hamilton JA. How fatty acids bind to proteins: the inside story from protein structures. Prostaglandins Leukot Essent Fatty Acids 2002;67:65-72.
-
(2002)
Prostaglandins Leukot Essent Fatty Acids
, vol.67
, pp. 65-72
-
-
Hamilton, J.A.1
-
23
-
-
0036812909
-
Mechanism of cellular uptake of long-chain fatty acids: do we need cellular proteins?
-
Hamilton JA, Guo W, Kamp F. Mechanism of cellular uptake of long-chain fatty acids: do we need cellular proteins? Mol Cell Biochem 2002;239:17-23.
-
(2002)
Mol Cell Biochem
, vol.239
, pp. 17-23
-
-
Hamilton, J.A.1
Guo, W.2
Kamp, F.3
-
24
-
-
0037424401
-
Rapid flip-flop of oleic acid across the plasma membrane of adipocytes
-
Kamp F, Guo W, Souto R, Pilch PF, Corkey BE, Hamilton JA. Rapid flip-flop of oleic acid across the plasma membrane of adipocytes. J Biol Chem 2003;278:7988-95.
-
(2003)
J Biol Chem
, vol.278
, pp. 7988-7995
-
-
Kamp, F.1
Guo, W.2
Souto, R.3
Pilch, P.F.4
Corkey, B.E.5
Hamilton, J.A.6
-
25
-
-
0029948676
-
Localization and regulation of the putative membrane fatty-acid transporter (FAT) in the small intestine. Comparison with fatty acid-binding proteins (FABP)
-
Poirier H, Degrace P, Niot I, Bernard A, Besnard P. Localization and regulation of the putative membrane fatty-acid transporter (FAT) in the small intestine. Comparison with fatty acid-binding proteins (FABP). Eur J Biochem 1996;238:368-73.
-
(1996)
Eur J Biochem
, vol.238
, pp. 368-373
-
-
Poirier, H.1
Degrace, P.2
Niot, I.3
Bernard, A.4
Besnard, P.5
-
26
-
-
0029830285
-
Up-regulation of the expression of the gene for liver fatty acid-binding protein by long-chain fatty acids
-
Meunier-Durmort C, Poirier H, Niot I, Forest C, Besnard P. Up-regulation of the expression of the gene for liver fatty acid-binding protein by long-chain fatty acids. Biochem J 1996;319:483-7.
-
(1996)
Biochem J
, vol.319
, pp. 483-487
-
-
Meunier-Durmort, C.1
Poirier, H.2
Niot, I.3
Forest, C.4
Besnard, P.5
-
27
-
-
0030889638
-
Disruption of the Saccharomyces cerevisiae homologue to the murine fatty acid transport protein impairs uptake and growth on long-chain fatty acids
-
Faergeman NJ, DiRusso CC, Elberger A, Knudsen J, Black PN. Disruption of the Saccharomyces cerevisiae homologue to the murine fatty acid transport protein impairs uptake and growth on long-chain fatty acids. J Biol Chem 1997;272:8531-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 8531-8538
-
-
Faergeman, N.J.1
DiRusso, C.C.2
Elberger, A.3
Knudsen, J.4
Black, P.N.5
-
28
-
-
0032444832
-
Membrane transport of long-chain fatty acids: evidence for a facilitated process
-
Abumrad N, Harmon C, Ibrahimi A. Membrane transport of long-chain fatty acids: evidence for a facilitated process. J Lipid Res 1998;39:2309-18.
-
(1998)
J Lipid Res
, vol.39
, pp. 2309-2318
-
-
Abumrad, N.1
Harmon, C.2
Ibrahimi, A.3
-
29
-
-
0033197543
-
Identification of the major intestinal fatty acid transport protein
-
Stahl A, Hirsch DJ, Gimeno RE, Punreddy S, Ge P, Watson N et al. Identification of the major intestinal fatty acid transport protein. Mol Cell 1999;4:299-308.
-
(1999)
Mol Cell
, vol.4
, pp. 299-308
-
-
Stahl, A.1
Hirsch, D.J.2
Gimeno, R.E.3
Punreddy, S.4
Ge, P.5
Watson, N.6
-
30
-
-
1542782154
-
Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality
-
Gimeno RE, Hirsch DJ, Punreddy S, Sun Y, Ortegon AM, Wu H et al. Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality. J Biol Chem 2003;278:49512-6.
-
(2003)
J Biol Chem
, vol.278
, pp. 49512-49516
-
-
Gimeno, R.E.1
Hirsch, D.J.2
Punreddy, S.3
Sun, Y.4
Ortegon, A.M.5
Wu, H.6
-
31
-
-
77951976294
-
Fatty acid transport across the cell membrane: regulation by fatty acid transporters
-
Schwenk RW, Holloway GP, Luiken JJ, Bonen A, Glatz JF. Fatty acid transport across the cell membrane: regulation by fatty acid transporters. Prostaglandins Leukot Essent Fatty Acids 2010;82:149-54.
-
(2010)
Prostaglandins Leukot Essent Fatty Acids
, vol.82
, pp. 149-154
-
-
Schwenk, R.W.1
Holloway, G.P.2
Luiken, J.J.3
Bonen, A.4
Glatz, J.F.5
-
32
-
-
33847127557
-
Is membrane transport of FFA mediated by lipid, protein, or both? An unknown protein mediates free fatty acid transport across the adipocyte plasma membrane
-
Kampf JP, Kleinfeld AM. Is membrane transport of FFA mediated by lipid, protein, or both? An unknown protein mediates free fatty acid transport across the adipocyte plasma membrane. Physiology (Bethesda) 2007;22:7-14.
-
(2007)
Physiology (Bethesda)
, vol.22
, pp. 7-14
-
-
Kampf, J.P.1
Kleinfeld, A.M.2
-
33
-
-
34447533581
-
Is membrane transport of FFA mediated by lipid, protein, or both? Mechanisms and regulation of protein-mediated cellular fatty acid uptake: molecular, biochemical, and physiological evidence
-
Bonen A, Chabowski A, Luiken JJ, Glatz JF. Is membrane transport of FFA mediated by lipid, protein, or both? Mechanisms and regulation of protein-mediated cellular fatty acid uptake: molecular, biochemical, and physiological evidence. Physiology (Bethesda) 2007;22:15-29.
-
(2007)
Physiology (Bethesda)
, vol.22
, pp. 15-29
-
-
Bonen, A.1
Chabowski, A.2
Luiken, J.J.3
Glatz, J.F.4
-
34
-
-
36749103888
-
Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane
-
Chabowski A, Gorski J, Luiken JJ, Glatz JF, Bonen A. Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane. Prostaglandins Leukot Essent Fatty Acids 2007;77:345-53.
-
(2007)
Prostaglandins Leukot Essent Fatty Acids
, vol.77
, pp. 345-353
-
-
Chabowski, A.1
Gorski, J.2
Luiken, J.J.3
Glatz, J.F.4
Bonen, A.5
-
35
-
-
36649006484
-
New insights into the roles of proteins and lipids in membrane transport of fatty acids
-
Hamilton JA. New insights into the roles of proteins and lipids in membrane transport of fatty acids. Prostaglandins Leukot Essent Fatty Acids 2007;77:355-61.
-
(2007)
Prostaglandins Leukot Essent Fatty Acids
, vol.77
, pp. 355-361
-
-
Hamilton, J.A.1
-
36
-
-
74949084316
-
Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease
-
Glatz JF, Luiken JJ, Bonen A. Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease. Physiol Rev 2010;90:367-417.
-
(2010)
Physiol Rev
, vol.90
, pp. 367-417
-
-
Glatz, J.F.1
Luiken, J.J.2
Bonen, A.3
-
37
-
-
77956413188
-
Fatty acid- and cholesterol transporter protein expression along the human intestinal tract
-
Masson CJ, Plat J, Mensink RP, Namiot A, Kisielewski W, Namiot Z et al. Fatty acid- and cholesterol transporter protein expression along the human intestinal tract. PLoS One 2010;5:e10380.
-
(2010)
PLoS One
, vol.5
-
-
Masson, C.J.1
Plat, J.2
Mensink, R.P.3
Namiot, A.4
Kisielewski, W.5
Namiot, Z.6
-
38
-
-
61449111753
-
Intestinal absorption of long-chain fatty acids: evidence and uncertainties
-
Niot I, Poirier H, Tran TT, Besnard P. Intestinal absorption of long-chain fatty acids: evidence and uncertainties. Prog Lipid Res 2009;48:101-15.
-
(2009)
Prog Lipid Res
, vol.48
, pp. 101-115
-
-
Niot, I.1
Poirier, H.2
Tran, T.T.3
Besnard, P.4
-
39
-
-
17744390348
-
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
-
Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J et al. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 2000;290:1771-5.
-
(2000)
Science
, vol.290
, pp. 1771-1775
-
-
Berge, K.E.1
Tian, H.2
Graf, G.A.3
Yu, L.4
Grishin, N.V.5
Schultz, J.6
-
40
-
-
0035158733
-
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption
-
Lee MH, Lu K, Hazard S, Yu H, Shulenin S, Hidaka H et al. Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat Genet 2001;27:79-83.
-
(2001)
Nat Genet
, vol.27
, pp. 79-83
-
-
Lee, M.H.1
Lu, K.2
Hazard, S.3
Yu, H.4
Shulenin, S.5
Hidaka, H.6
-
41
-
-
0036733630
-
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
-
Yu L, Li-Hawkins J, Hammer RE, Berge KE, Horton JD, Cohen JC et al. Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J Clin Invest 2002;110:671-80.
-
(2002)
J Clin Invest
, vol.110
, pp. 671-680
-
-
Yu, L.1
Li-Hawkins, J.2
Hammer, R.E.3
Berge, K.E.4
Horton, J.D.5
Cohen, J.C.6
-
42
-
-
0037058995
-
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
-
Yu L, Hammer RE, Li-Hawkins J, Von Bergmann K, Lutjohann D, Cohen JC et al. Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc Natl Acad Sci USA 2002;99:16237-42.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16237-16242
-
-
Yu, L.1
Hammer, R.E.2
Li-Hawkins, J.3
Von Bergmann, K.4
Lutjohann, D.5
Cohen, J.C.6
-
43
-
-
34247399882
-
Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8(-/-) mice
-
Wang HH, Patel SB, Carey MC, Wang DQ. Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8(-/-) mice. Hepatology 2007;45:998-1006.
-
(2007)
Hepatology
, vol.45
, pp. 998-1006
-
-
Wang, H.H.1
Patel, S.B.2
Carey, M.C.3
Wang, D.Q.4
-
44
-
-
3042522984
-
Cholesterol absorption is mainly regulated by the jejunal and ileal ATP-binding cassette sterol efflux transporters Abcg5 and Abcg8 in mice
-
Duan LP, Wang HH, Wang DQ. Cholesterol absorption is mainly regulated by the jejunal and ileal ATP-binding cassette sterol efflux transporters Abcg5 and Abcg8 in mice. J Lipid Res 2004;45:1312-23.
-
(2004)
J Lipid Res
, vol.45
, pp. 1312-1323
-
-
Duan, L.P.1
Wang, H.H.2
Wang, D.Q.3
-
45
-
-
0034003105
-
Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663
-
van Heek M, Farley C, Compton DS, Hoos L, Alton KB, Sybertz EJ et al. Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663. Br J Pharmacol 2000;129:1748-54.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 1748-1754
-
-
van Heek, M.1
Farley, C.2
Compton, D.S.3
Hoos, L.4
Alton, K.B.5
Sybertz, E.J.6
-
46
-
-
10744221008
-
Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption
-
Altmann SW, Davis HR Jr, Zhu LJ, Yao X, Hoos LM, Tetzloff G et al. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science 2004;303:1201-4.
-
(2004)
Science
, vol.303
, pp. 1201-1204
-
-
Altmann, S.W.1
Davis Jr., H.R.2
Zhu, L.J.3
Yao, X.4
Hoos, L.M.5
Tetzloff, G.6
-
47
-
-
4043124013
-
Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis
-
Davis HR Jr, Zhu LJ, Hoos LM, Tetzloff G, Maguire M, Liu J et al. Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis. J Biol Chem 2004;279:33586-92.
-
(2004)
J Biol Chem
, vol.279
, pp. 33586-33592
-
-
Davis Jr., H.R.1
Zhu, L.J.2
Hoos, L.M.3
Tetzloff, G.4
Maguire, M.5
Liu, J.6
-
48
-
-
44349126634
-
The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1
-
Ge L, Wang J, Qi W, Miao HH, Cao J, Qu YX et al. The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1. Cell Metab 2008;7:508-19.
-
(2008)
Cell Metab
, vol.7
, pp. 508-519
-
-
Ge, L.1
Wang, J.2
Qi, W.3
Miao, H.H.4
Cao, J.5
Qu, Y.X.6
-
49
-
-
0021367211
-
Reduced cholesterol transmucosal transport in rats with inhibited mucosal acyl CoA:cholesterol acyltransferase and normal pancreatic function
-
Clark SB, Tercyak AM. Reduced cholesterol transmucosal transport in rats with inhibited mucosal acyl CoA:cholesterol acyltransferase and normal pancreatic function. J Lipid Res 1984;25:148-59.
-
(1984)
J Lipid Res
, vol.25
, pp. 148-159
-
-
Clark, S.B.1
Tercyak, A.M.2
-
50
-
-
0034529633
-
Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice
-
Buhman KK, Accad M, Novak S, Choi RS, Wong JS, Hamilton RL et al. Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice. Nat Med 2000;6:1341-7.
-
(2000)
Nat Med
, vol.6
, pp. 1341-1347
-
-
Buhman, K.K.1
Accad, M.2
Novak, S.3
Choi, R.S.4
Wong, J.S.5
Hamilton, R.L.6
-
51
-
-
0031882256
-
Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: interaction with saturated and unsaturated dietary fatty acids
-
van Greevenbroek MM, Robertus-Teunissen MG, Erkelens DW, de Bruin TW. Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: interaction with saturated and unsaturated dietary fatty acids. J Lipid Res 1998;39:173-85.
-
(1998)
J Lipid Res
, vol.39
, pp. 173-185
-
-
van Greevenbroek, M.M.1
Robertus-Teunissen, M.G.2
Erkelens, D.W.3
de Bruin, T.W.4
-
52
-
-
0021018405
-
Surface-to-core and interparticle equilibrium distributions of triglyceride-rich lipoprotein lipids
-
Miller KW, Small DM. Surface-to-core and interparticle equilibrium distributions of triglyceride-rich lipoprotein lipids. J Biol Chem 1983;258:13772-84.
-
(1983)
J Biol Chem
, vol.258
, pp. 13772-13784
-
-
Miller, K.W.1
Small, D.M.2
-
53
-
-
0021107170
-
Triolein-cholesteryl oleate-cholesterol-lecithin emulsions: structural models of triglyceride-rich lipoproteins
-
Miller KW, Small DM. Triolein-cholesteryl oleate-cholesterol-lecithin emulsions: structural models of triglyceride-rich lipoproteins. Biochemistry 1983;22:443-51.
-
(1983)
Biochemistry
, vol.22
, pp. 443-451
-
-
Miller, K.W.1
Small, D.M.2
-
54
-
-
0013809384
-
The composition and structure of lymph chylomicrons in dog, rat, and man
-
Zilversmit DB. The composition and structure of lymph chylomicrons in dog, rat, and man. J Clin Invest 1965;44:1610-22.
-
(1965)
J Clin Invest
, vol.44
, pp. 1610-1622
-
-
Zilversmit, D.B.1
-
55
-
-
0016834694
-
Chylomicron formation and composition in unanaesthetised rabbits
-
Redgrave TG, Dunne KB. Chylomicron formation and composition in unanaesthetised rabbits. Atherosclerosis 1975;22:389-400.
-
(1975)
Atherosclerosis
, vol.22
, pp. 389-400
-
-
Redgrave, T.G.1
Dunne, K.B.2
-
56
-
-
0023617743
-
Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon
-
Chen SH, Habib G, Yang CY, Gu ZW, Lee BR, Weng SA et al. Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon. Science 1987;238:363-6.
-
(1987)
Science
, vol.238
, pp. 363-366
-
-
Chen, S.H.1
Habib, G.2
Yang, C.Y.3
Gu, Z.W.4
Lee, B.R.5
Weng, S.A.6
-
57
-
-
0023651359
-
A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine
-
Powell LM, Wallis SC, Pease RJ, Edwards YH, Knott TJ, Scott J. A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine. Cell 1987;50:831-40.
-
(1987)
Cell
, vol.50
, pp. 831-840
-
-
Powell, L.M.1
Wallis, S.C.2
Pease, R.J.3
Edwards, Y.H.4
Knott, T.J.5
Scott, J.6
-
58
-
-
0033991176
-
A proposed model for the assembly of chylomicrons
-
Hussain MM. A proposed model for the assembly of chylomicrons. Atherosclerosis 2000;148:1-15.
-
(2000)
Atherosclerosis
, vol.148
, pp. 1-15
-
-
Hussain, M.M.1
-
59
-
-
0029044556
-
Intestinal lipoprotein synthesis and secretion
-
Field FJ, Mathur SN. Intestinal lipoprotein synthesis and secretion. Prog Lipid Res 1995;34:185-98.
-
(1995)
Prog Lipid Res
, vol.34
, pp. 185-198
-
-
Field, F.J.1
Mathur, S.N.2
-
60
-
-
0031846319
-
Chylomicron-sized lipid particles are formed in the setting of apolipoprotein B deficiency
-
Hamilton RL, Wong JS, Cham CM, Nielsen LB, Young SG. Chylomicron-sized lipid particles are formed in the setting of apolipoprotein B deficiency. J Lipid Res 1998;39:1543-57.
-
(1998)
J Lipid Res
, vol.39
, pp. 1543-1557
-
-
Hamilton, R.L.1
Wong, J.S.2
Cham, C.M.3
Nielsen, L.B.4
Young, S.G.5
-
61
-
-
0028821841
-
A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine
-
Young SG, Cham CM, Pitas RE, Burri BJ, Connolly A, Flynn L et al. A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine. J Clin Invest 1995;96:2932-46.
-
(1995)
J Clin Invest
, vol.96
, pp. 2932-2946
-
-
Young, S.G.1
Cham, C.M.2
Pitas, R.E.3
Burri, B.J.4
Connolly, A.5
Flynn, L.6
-
62
-
-
12644303527
-
Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step
-
Gordon DA, Jamil H, Gregg RE, Olofsson SO, Boren J. Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step. J Biol Chem 1996;271:33047-53.
-
(1996)
J Biol Chem
, vol.271
, pp. 33047-33053
-
-
Gordon, D.A.1
Jamil, H.2
Gregg, R.E.3
Olofsson, S.O.4
Boren, J.5
-
63
-
-
0034078501
-
Genetic determinants of plasma lipid response to dietary intervention: the role of the APOA1/C3/A4 gene cluster and the APOE gene
-
Ordovas JM, Schaefer EJ. Genetic determinants of plasma lipid response to dietary intervention: the role of the APOA1/C3/A4 gene cluster and the APOE gene. Br J Nutr 2000;83(Suppl 1):S127-36.
-
(2000)
Br J Nutr
, vol.83
, Issue.SUPPL. 1
-
-
Ordovas, J.M.1
Schaefer, E.J.2
-
64
-
-
84879124147
-
Role the TICE?: advancing the concept of transintestinal cholesterol excretion
-
Tietge UJ, Groen AK. Role the TICE?: advancing the concept of transintestinal cholesterol excretion. Arterioscler Thromb Vasc Biol 2013;33:1452-3.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 1452-1453
-
-
Tietge, U.J.1
Groen, A.K.2
-
65
-
-
84879079456
-
Transintestinal cholesterol excretion is an active metabolic process modulated by PCSK9 and statin involving ABCB1
-
Le May C, Berger JM, Lespine A, Pillot B, Prieur X, Letessier E et al. Transintestinal cholesterol excretion is an active metabolic process modulated by PCSK9 and statin involving ABCB1. Arterioscler Thromb Vasc Biol 2013;33:1484-93.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 1484-1493
-
-
Le May, C.1
Berger, J.M.2
Lespine, A.3
Pillot, B.4
Prieur, X.5
Letessier, E.6
-
66
-
-
84878472293
-
Intestinal caveolin-1 is important for dietary fatty acid absorption
-
Siddiqi S, Sheth A, Patel F, Barnes M, Mansbach CM 2nd. Intestinal caveolin-1 is important for dietary fatty acid absorption. Biochim Biophys Acta 2013;1831:1311-21.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 1311-1321
-
-
Siddiqi, S.1
Sheth, A.2
Patel, F.3
Barnes, M.4
Mansbach II, C.M.5
-
67
-
-
80052051567
-
CD36 as a lipid sensor
-
Martin C, Chevrot M, Poirier H, Passilly-Degrace P, Niot I, Besnard P. CD36 as a lipid sensor. Physiol Behav 2011;105:36-42.
-
(2011)
Physiol Behav
, vol.105
, pp. 36-42
-
-
Martin, C.1
Chevrot, M.2
Poirier, H.3
Passilly-Degrace, P.4
Niot, I.5
Besnard, P.6
-
68
-
-
34547124866
-
CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine
-
Nassir F, Wilson B, Han X, Gross RW, Abumrad NA. CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine. J Biol Chem 2007;282:19493-501.
-
(2007)
J Biol Chem
, vol.282
, pp. 19493-19501
-
-
Nassir, F.1
Wilson, B.2
Han, X.3
Gross, R.W.4
Abumrad, N.A.5
-
69
-
-
0033815312
-
The intestinal fatty acid binding protein is not essential for dietary fat absorption in mice
-
Vassileva G, Huwyler L, Poirier K, Agellon LB, Toth MJ. The intestinal fatty acid binding protein is not essential for dietary fat absorption in mice. FASEB J 2000;14:2040-6.
-
(2000)
FASEB J
, vol.14
, pp. 2040-2046
-
-
Vassileva, G.1
Huwyler, L.2
Poirier, K.3
Agellon, L.B.4
Toth, M.J.5
-
70
-
-
64349089728
-
Fatty acid transport protein 4 is dispensable for intestinal lipid absorption in mice
-
Shim J, Moulson CL, Newberry EP, Lin MH, Xie Y, Kennedy SM et al. Fatty acid transport protein 4 is dispensable for intestinal lipid absorption in mice. J Lipid Res 2009;50:491-500.
-
(2009)
J Lipid Res
, vol.50
, pp. 491-500
-
-
Shim, J.1
Moulson, C.L.2
Newberry, E.P.3
Lin, M.H.4
Xie, Y.5
Kennedy, S.M.6
-
71
-
-
18244393432
-
CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood
-
Drover VA, Ajmal M, Nassir F, Davidson NO, Nauli AM, Sahoo D et al. CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. J Clin Invest 2005;115:1290-7.
-
(2005)
J Clin Invest
, vol.115
, pp. 1290-1297
-
-
Drover, V.A.1
Ajmal, M.2
Nassir, F.3
Davidson, N.O.4
Nauli, A.M.5
Sahoo, D.6
-
72
-
-
67649381418
-
Chylomicron remnants are increased in the postprandial state in CD36 deficiency
-
Masuda D, Hirano K, Oku H, Sandoval JC, Kawase R, Yuasa-Kawase M et al. Chylomicron remnants are increased in the postprandial state in CD36 deficiency. J Lipid Res 2009;50:999-1011.
-
(2009)
J Lipid Res
, vol.50
, pp. 999-1011
-
-
Masuda, D.1
Hirano, K.2
Oku, H.3
Sandoval, J.C.4
Kawase, R.5
Yuasa-Kawase, M.6
-
73
-
-
57349106472
-
Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1 l1-/- mice
-
Labonte ED, Camarota LM, Rojas JC, Jandacek RJ, Gilham DE, Davies JP et al. Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1 l1-/- mice. Am J Physiol 2008;295:G776-83.
-
(2008)
Am J Physiol
, vol.295
-
-
Labonte, E.D.1
Camarota, L.M.2
Rojas, J.C.3
Jandacek, R.J.4
Gilham, D.E.5
Davies, J.P.6
-
74
-
-
84864401578
-
Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid
-
Walters JW, Anderson JL, Bittman R, Pack M, Farber SA. Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid. Chem Biol 2012;19:913-25.
-
(2012)
Chem Biol
, vol.19
, pp. 913-925
-
-
Walters, J.W.1
Anderson, J.L.2
Bittman, R.3
Pack, M.4
Farber, S.A.5
-
75
-
-
79955574217
-
Zebrafish lipid metabolism: from mediating early patterning to the metabolism of dietary fat and cholesterol
-
Anderson JL, Carten JD, Farber SA. Zebrafish lipid metabolism: from mediating early patterning to the metabolism of dietary fat and cholesterol. Methods Cell Biol 2011;101:111-41.
-
(2011)
Methods Cell Biol
, vol.101
, pp. 111-141
-
-
Anderson, J.L.1
Carten, J.D.2
Farber, S.A.3
-
76
-
-
33646867424
-
Lymphatic chylomicron size is inversely related to biliary phospholipid secretion in mice
-
Werner A, Havinga R, Perton F, Kuipers F, Verkade HJ. Lymphatic chylomicron size is inversely related to biliary phospholipid secretion in mice. Am J Physiol 2006;290:G1177-85.
-
(2006)
Am J Physiol
, vol.290
-
-
Werner, A.1
Havinga, R.2
Perton, F.3
Kuipers, F.4
Verkade, H.J.5
-
77
-
-
2942635697
-
Administration of phosphatidylcholine-cholesterol liposomes partially reconstitutes fat absorption in chronically bile-diverted rats
-
Nishioka T, Having R, Tazuma S, Stellaard F, Kuipers F, Verkade HJ. Administration of phosphatidylcholine-cholesterol liposomes partially reconstitutes fat absorption in chronically bile-diverted rats. Biochim Biophys Acta 2004;1636:90-8.
-
(2004)
Biochim Biophys Acta
, vol.1636
, pp. 90-98
-
-
Nishioka, T.1
Having, R.2
Tazuma, S.3
Stellaard, F.4
Kuipers, F.5
Verkade, H.J.6
-
78
-
-
0014499424
-
The mechanism of fat absorption in the bile fistula rat
-
Morgan RG, Borgstrom B. The mechanism of fat absorption in the bile fistula rat. Q J Exp Physiol Cogn Med Sci 1969;54:228-43.
-
(1969)
Q J Exp Physiol Cogn Med Sci
, vol.54
, pp. 228-243
-
-
Morgan, R.G.1
Borgstrom, B.2
-
79
-
-
0020322491
-
Influence of small-bowel transit time on dietary cholesterol absorption in human beings
-
Ponz de Leon M, Iori R, Barbolini G, Pompei G, Zaniol P, Carulli N. Influence of small-bowel transit time on dietary cholesterol absorption in human beings. N Engl J Med 1982;307:102-3.
-
(1982)
N Engl J Med
, vol.307
, pp. 102-103
-
-
Ponz de Leon, M.1
Iori, R.2
Barbolini, G.3
Pompei, G.4
Zaniol, P.5
Carulli, N.6
-
80
-
-
85047693084
-
Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis
-
Wang DQ, Schmitz F, Kopin AS, Carey MC. Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis. J Clin Invest 2004;114:521-8.
-
(2004)
J Clin Invest
, vol.114
, pp. 521-528
-
-
Wang, D.Q.1
Schmitz, F.2
Kopin, A.S.3
Carey, M.C.4
-
81
-
-
0032824544
-
Hydrogenation of polyunsaturated fatty acids by human colonic bacteria
-
Howard FA, Henderson C. Hydrogenation of polyunsaturated fatty acids by human colonic bacteria. Lett Appl Microbiol 1999;29:193-6.
-
(1999)
Lett Appl Microbiol
, vol.29
, pp. 193-196
-
-
Howard, F.A.1
Henderson, C.2
-
82
-
-
0041912965
-
Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: an analysis of direct versus indirect methodologies
-
Wang DQ, Carey MC. Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: an analysis of direct versus indirect methodologies. J Lipid Res 2003;44:1042-59.
-
(2003)
J Lipid Res
, vol.44
, pp. 1042-1059
-
-
Wang, D.Q.1
Carey, M.C.2
-
83
-
-
0017336362
-
Estimation of fat absorption from single fecal specimens using 131I-triolein and 75Se-triether. A study in rats with and without induced steatorrhea
-
Hoving J, Wilson JH, Valkema AJ, Woldring MG. Estimation of fat absorption from single fecal specimens using 131I-triolein and 75Se-triether. A study in rats with and without induced steatorrhea. Gastroenterology 1977;72:406-12.
-
(1977)
Gastroenterology
, vol.72
, pp. 406-412
-
-
Hoving, J.1
Wilson, J.H.2
Valkema, A.J.3
Woldring, M.G.4
-
84
-
-
0014785326
-
Use of 3H-labeled triether, a nonabsorbable oil-phase marker, to estimate fat absorption in rats with cholestyramine-induced steatorrhea
-
Morgan RG, Hofmann AF. Use of 3H-labeled triether, a nonabsorbable oil-phase marker, to estimate fat absorption in rats with cholestyramine-induced steatorrhea. J Lipid Res 1970;11:231-6.
-
(1970)
J Lipid Res
, vol.11
, pp. 231-236
-
-
Morgan, R.G.1
Hofmann, A.F.2
-
85
-
-
0014783757
-
Synthesis and metabolism of glycerol-3H triether, a nonabsorbable oil-phase marker for lipid absorption studies
-
Morgan RG, Hofmann AF. Synthesis and metabolism of glycerol-3H triether, a nonabsorbable oil-phase marker for lipid absorption studies. J Lipid Res 1970;11:223-30.
-
(1970)
J Lipid Res
, vol.11
, pp. 223-230
-
-
Morgan, R.G.1
Hofmann, A.F.2
-
86
-
-
0014402463
-
Intestinal absorption of lecithin and lysolecithin by lymph fistula rats
-
Nilsson A. Intestinal absorption of lecithin and lysolecithin by lymph fistula rats. Biochim Biophys Acta 1968;152:379-90.
-
(1968)
Biochim Biophys Acta
, vol.152
, pp. 379-390
-
-
Nilsson, A.1
-
87
-
-
0014199183
-
Incorporation of dietary lecithin and lysolecithin into lymph chylomicrons in the rat
-
Scow RO, Stein Y, Stein O. Incorporation of dietary lecithin and lysolecithin into lymph chylomicrons in the rat. J Biol Chem 1967;242:4919-24.
-
(1967)
J Biol Chem
, vol.242
, pp. 4919-4924
-
-
Scow, R.O.1
Stein, Y.2
Stein, O.3
-
88
-
-
0014543942
-
Intestinal absorption and lymphatic transport of cholesterol in the rat: influence of the fatty acid chain length of the carrier triglyceride
-
Sylven C, Borgstrom B. Intestinal absorption and lymphatic transport of cholesterol in the rat: influence of the fatty acid chain length of the carrier triglyceride. J Lipid Res 1969;10:351-5.
-
(1969)
J Lipid Res
, vol.10
, pp. 351-355
-
-
Sylven, C.1
Borgstrom, B.2
-
89
-
-
0023653657
-
Factors regulating the formation of chylomicrons and very-low-density lipoproteins by the rat small intestine
-
Tso P, Lindstrom MB, Borgstrom B. Factors regulating the formation of chylomicrons and very-low-density lipoproteins by the rat small intestine. Biochim Biophys Acta 1987;922:304-13.
-
(1987)
Biochim Biophys Acta
, vol.922
, pp. 304-313
-
-
Tso, P.1
Lindstrom, M.B.2
Borgstrom, B.3
-
90
-
-
0035199905
-
Genetic factors at the enterocyte level account for variations in intestinal cholesterol absorption efficiency among inbred strains of mice
-
Wang DQ, Paigen B, Carey MC. Genetic factors at the enterocyte level account for variations in intestinal cholesterol absorption efficiency among inbred strains of mice. J Lipid Res 2001;42:1820-30.
-
(2001)
J Lipid Res
, vol.42
, pp. 1820-1830
-
-
Wang, D.Q.1
Paigen, B.2
Carey, M.C.3
-
91
-
-
17644373076
-
GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats
-
Qin X, Shen H, Liu M, Yang Q, Zheng S, Sabo M et al. GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats. Am J Physiol 2005;288:G943-9.
-
(2005)
Am J Physiol
, vol.288
-
-
Qin, X.1
Shen, H.2
Liu, M.3
Yang, Q.4
Zheng, S.5
Sabo, M.6
-
92
-
-
80053460336
-
Using the lymphatics to study nutrient absorption and the secretion of gastrointestinal hormones
-
Kohan AB, Yoder SM, Tso P. Using the lymphatics to study nutrient absorption and the secretion of gastrointestinal hormones. Physiol Behav 2011;105:82-8.
-
(2011)
Physiol Behav
, vol.105
, pp. 82-88
-
-
Kohan, A.B.1
Yoder, S.M.2
Tso, P.3
-
93
-
-
3242735983
-
A novel, noninvasive method for the measurement of intestinal fat absorption
-
Jandacek RJ, Heubi JE, Tso P. A novel, noninvasive method for the measurement of intestinal fat absorption. Gastroenterology 2004;127:139-44.
-
(2004)
Gastroenterology
, vol.127
, pp. 139-144
-
-
Jandacek, R.J.1
Heubi, J.E.2
Tso, P.3
-
94
-
-
0032506273
-
Mechanism of action of fibrates on lipid and lipoprotein metabolism
-
Staels B, Dallongeville J, Auwerx J, Schoonjans K, Leitersdorf E, Fruchart JC. Mechanism of action of fibrates on lipid and lipoprotein metabolism. Circulation 1998;98:2088-93.
-
(1998)
Circulation
, vol.98
, pp. 2088-2093
-
-
Staels, B.1
Dallongeville, J.2
Auwerx, J.3
Schoonjans, K.4
Leitersdorf, E.5
Fruchart, J.C.6
-
95
-
-
0033379344
-
Fibrates, dyslipoproteinaemia and cardiovascular disease
-
Watts GF, Dimmitt SB. Fibrates, dyslipoproteinaemia and cardiovascular disease. Curr Opin Lipidol 1999;10:561-74.
-
(1999)
Curr Opin Lipidol
, vol.10
, pp. 561-574
-
-
Watts, G.F.1
Dimmitt, S.B.2
-
96
-
-
11844296800
-
Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials
-
Birjmohun RS, Hutten BA, Kastelein JJ, Stroes ES. Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials. J Am Coll Cardiol 2005;45:185-97.
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 185-197
-
-
Birjmohun, R.S.1
Hutten, B.A.2
Kastelein, J.J.3
Stroes, E.S.4
-
97
-
-
0036424159
-
Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia
-
Sudhop T, von Bergmann K. Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia. Drugs 2002;62:2333-47.
-
(2002)
Drugs
, vol.62
, pp. 2333-2347
-
-
Sudhop, T.1
von Bergmann, K.2
-
98
-
-
9544237127
-
2-Azetidinone cholesterol absorption inhibitors: structure-activity relationships on the heterocyclic nucleus
-
Clader JW, Burnett DA, Caplen MA, Domalski MS, Dugar S, Vaccaro W et al. 2-Azetidinone cholesterol absorption inhibitors: structure-activity relationships on the heterocyclic nucleus. J Med Chem 1996;39:3684-93.
-
(1996)
J Med Chem
, vol.39
, pp. 3684-3693
-
-
Clader, J.W.1
Burnett, D.A.2
Caplen, M.A.3
Domalski, M.S.4
Dugar, S.5
Vaccaro, W.6
-
99
-
-
0030848734
-
In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461
-
Van Heek M, France CF, Compton DS, McLeod RL, Yumibe NP, Alton KB et al. In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461. J Pharmacol Exp Ther 1997;283:157-63.
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 157-163
-
-
Van Heek, M.1
France, C.F.2
Compton, D.S.3
McLeod, R.L.4
Yumibe, N.P.5
Alton, K.B.6
-
100
-
-
0034985134
-
A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe
-
Ezzet F, Krishna G, Wexler DB, Statkevich P, Kosoglou T, Batra VK. A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe. Clin Ther 2001;23:871-85.
-
(2001)
Clin Ther
, vol.23
, pp. 871-885
-
-
Ezzet, F.1
Krishna, G.2
Wexler, D.B.3
Statkevich, P.4
Kosoglou, T.5
Batra, V.K.6
-
101
-
-
0034776367
-
Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function
-
van Heek M, Farley C, Compton DS, Hoos L, Davis HR. Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function. Br J Pharmacol 2001;134:409-17.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 409-417
-
-
van Heek, M.1
Farley, C.2
Compton, D.S.3
Hoos, L.4
Davis, H.R.5
-
102
-
-
0344490262
-
Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial
-
Melani L, Mills R, Hassman D, Lipetz R, Lipka L, LeBeaut A et al. Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. Eur Heart J 2003;24:717-28.
-
(2003)
Eur Heart J
, vol.24
, pp. 717-728
-
-
Melani, L.1
Mills, R.2
Hassman, D.3
Lipetz, R.4
Lipka, L.5
LeBeaut, A.6
-
103
-
-
2942574385
-
Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goals
-
Feldman T, Koren M, Insull W Jr, McKenney J, Schrott H, Lewin A et al. Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goals. Am J Cardiol 2004;93:1481-6.
-
(2004)
Am J Cardiol
, vol.93
, pp. 1481-1486
-
-
Feldman, T.1
Koren, M.2
Insull Jr., W.3
McKenney, J.4
Schrott, H.5
Lewin, A.6
-
104
-
-
41149120450
-
Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice
-
Zheng S, Hoos L, Cook J, Tetzloff G, Davis H Jr, van Heek M et al. Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice. Eur J Pharmacol 2008;584:118-24.
-
(2008)
Eur J Pharmacol
, vol.584
, pp. 118-124
-
-
Zheng, S.1
Hoos, L.2
Cook, J.3
Tetzloff, G.4
Davis Jr., H.5
van Heek, M.6
-
105
-
-
57349162139
-
Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters
-
Valasek MA, Repa JJ, Quan G, Dietschy JM, Turley SD. Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters. Am J Physiol 2008;295:G813-22.
-
(2008)
Am J Physiol
, vol.295
-
-
Valasek, M.A.1
Repa, J.J.2
Quan, G.3
Dietschy, J.M.4
Turley, S.D.5
-
106
-
-
36549013633
-
Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome
-
Deushi M, Nomura M, Kawakami A, Haraguchi M, Ito M, Okazaki M et al. Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome. FEBS Lett 2007;581:5664-70.
-
(2007)
FEBS Lett
, vol.581
, pp. 5664-5670
-
-
Deushi, M.1
Nomura, M.2
Kawakami, A.3
Haraguchi, M.4
Ito, M.5
Okazaki, M.6
-
107
-
-
78149348442
-
Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis
-
Jia L, Ma Y, Rong S, Betters JL, Xie P, Chung S et al. Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis. J Lipid Res 2010;51:3135-44.
-
(2010)
J Lipid Res
, vol.51
, pp. 3135-3144
-
-
Jia, L.1
Ma, Y.2
Rong, S.3
Betters, J.L.4
Xie, P.5
Chung, S.6
-
108
-
-
84859929103
-
Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic fatty liver disease
-
de Bari O, Neuschwander-Tetri BA, Liu M, Portincasa P, Wang DQ. Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic fatty liver disease. J Lipids 2012;2012:302847.
-
(2012)
J Lipids
, vol.2012
, pp. 302847
-
-
de Bari, O.1
Neuschwander-Tetri, B.A.2
Liu, M.3
Portincasa, P.4
Wang, D.Q.5
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