Standardized extract of bacopa monniera attenuates okadaic acid induced memory dysfunction in rats: Effect on Nrf2 pathway

Evidence-based Complementary and Alternative Medicine

Volumn 2013, Issue , 2013, Pages

  Dwivedi, Subhash ^a   Nagarajan, Rajasekar ^a   Hanif, Kashif ^a   Siddiqui, Hefazat Husain ^b   Nath, Chandishwar ^a   Shukla, Rakesh ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b INTEGRAL UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BACOPA MONNIERI EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; MELATONIN; OKADAIC ACID; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BACOPA MONNIERI; BRAIN CORTEX; CONTROLLED STUDY; HIPPOCAMPUS; LATENT PERIOD; MALE; MAZE TEST; MEMORY; MEMORY DISORDER; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 84885415815     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/294501     Document Type: Article

References (71)

1. McGeer E. G., McGeer P. L., Chronic inflammation in Alzheimer's disease offers therapeutic opportunities. Expert Review of Neurotherapeutics 2001 1 1 53 60 2-s2.0-0035741377 10.1586/14737175.1.1.53 (Pubitemid 34627368)
2. Ishii T., Itoh K., Yamamoto M., Roles of Nrf2 in activation of antioxidant enzyme genes via antioxidant responsive elements. Methods in Enzymology 2002 348 182 190 2-s2.0-0036371485 10.1016/S0076-6879(02)48637-5 (Pubitemid 41103109)
3. Kobayashi M., Yamamoto M., Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxidants and Redox Signaling 2005 7 3-4 385 394 2-s2.0-14044254798 10.1089/ars.2005.7.385 (Pubitemid 40279806)
4. Satoh T., Kosaka K., Itoh K., Kobayashi A., Yamamoto M., Shimojo Y., Kitajima C., Cui J., Kamins J., Okamoto S., Izumi M., Shirasawa T., Lipton S. A., Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1. Journal of Neurochemistry 2008 104 4 1116 1131 2-s2.0-38449111059 10.1111/j.1471-4159.2007.05039.x (Pubitemid 351143643)
5. Lee J., Calkins M. J., Chan K., Kan Y. W., Johnson J. A., Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. The Journal of Biological Chemistry 2003 278 14 12029 12038 2-s2.0-0038146898 10.1074/jbc.M211558200 (Pubitemid 36800179)
6. Rosales-Corral S., Reiter R. J., Tan D., Ortiz G. G., Lopez-Armas G., Functional aspects of redox control during neuroinflammation. Antioxidants and Redox Signaling 2010 13 2 193 247 2-s2.0-77953641852 10.1089/ars.2009.2629
7. Yamamoto Y., Gaynor R. B., Role of the NF- B pathway in the pathogenesis of human disease states. Current Molecular Medicine 2001 1 3 287 296 2-s2.0-0035411587 (Pubitemid 33773312)
8. Brun-Buisson C., The epidemiology of the systemic inflammatory response. Intensive Care Medicine, Supplement 2000 26 supplement 1 S64 S74 2-s2.0-0034108825 (Pubitemid 30184495)
9. Johnson G. V. W., Stoothoff W. H., Tau phosphorylation in neuronal cell function and dysfunction. Journal of Cell Science 2004 117 part 24 5721 5729 2-s2.0-12344323961 10.1242/jcs.01558 (Pubitemid 40123939)
10. Lace G., Savva G. M., Forster G., de Silva R., Brayne C., Matthews F. E., Barclay J. J., Dakin L., Ince P. G., Wharton S. B., Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study. Brain 2009 132 part 5 1324 1334 2-s2.0-66549109914 10.1093/brain/awp059
11. Gong C.-X., Shaikh S., Wang J.-Z., Zaidi T., Grundke-Iqbal I., Iqbal K., Phosphatase activity toward abnormally phosphorylated τ: decrease in Alzheimer disease brain. Journal of Neurochemistry 1995 65 2 732 738 2-s2.0-0029113874
12. Zhang C., Tian Q., Wei W., Peng J., Liu G., Zhou X., Wang Q., Wang D., Wang J., Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus. Neurobiology of Aging 2008 29 11 1654 1665 2-s2.0-51649119364 10.1016/j.neurobiolaging.2007.04.015
13. Higgins L. S., Rodems J. M., Catalano R., Quon D., Cordell B., Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for β -APP751. Proceedings of the National Academy of Sciences of the United States of America 1995 92 10 4402 4406 2-s2.0-0029064572
14. Kamat P. K., Rai S., Swarnkar S., Okadaic acid-induced Tau phosphorylation in rat brain: role of NMDA receptor. Neuroscience 2013 238 97 113
15. Cohen P., Holmes C. F. B., Tsukitani Y., Okadaic acid: a new probe for the study of cellular regulation. Trends in Biochemical Sciences 1990 15 3 98 102 2-s2.0-0025181418
16. Kamat P. K., Tota S., Saxena G., Shukla R., Nath C., Okadaic acid (ICV) induced memory impairment in rats: a suitable experimental model to test anti-dementia activity. Brain Research 2010 1309 66 74 2-s2.0-72049129673 10.1016/j.brainres.2009.10.064
17. Kamat P. K., Tota S., Shukla R., Ali S., Najmi A. K., Nath C., Mitochondrial dysfunction: a crucial event in okadaic acid (ICV) induced memory impairment and apoptotic cell death in rat brain. Pharmacology Biochemistry and Behavior 2011 100 2 311 319 2-s2.0-80054795374 10.1016/j.pbb.2011.08.019
18. Kamat P. K., Tota S., Rai S., Swarnkar S., Shukla R., Nath C., A study on neuroinflammatory marker in brain areas of okadaic acid (ICV) induced memory impaired rats. Life Sciences 2012 90 19-20 713 720 2-s2.0-84860118451 10.1016/j.lfs.2012.03.012
19. Rajasekar N., Dwivedi S., Tota S. K., Neuroprotective effect of curcumin on okadaic acid induced memory impairment in mice. European Journal of Pharmacology 2013 10.1016/j.ejphar.2013.04.033
20. Anuradha C. D., Kanno S., Hirano S., Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells. Free Radical Biology and Medicine 2001 31 3 367 373 2-s2.0-0035426001 10.1016/S0891-5849(01)00591-3 (Pubitemid 32675342)
21. Lee B. Y., Ban J. Y., Seong Y. H., Chronic stimulation of GABAA receptor with muscimol reduces amyloid β protein (25-35)-induced neurotoxicity in cultured rat cortical cells. Neuroscience Research 2005 52 4 347 356 2-s2.0-21444457744 10.1016/j.neures.2005.04.008 (Pubitemid 40917213)
22. Pettersson F., Dalgleish A. G., Bissonnette R. P., Colston K. W., Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR- γ and altered expression of Bcl-2/Bax. British Journal of Cancer 2002 87 5 555 561 2-s2.0-0037183674 10.1038/sj.bjc.6600496
23. Jarskog L. F., Selinger E. S., Lieberman J. A., Gilmore J. H., Apoptotic proteins in the temporal cortex in schizophrenia: high Bax/Bcl-2 ratio without caspase-3 activation. American Journal of Psychiatry 2004 161 1 109 115 2-s2.0-1442264399 10.1176/appi.ajp.161.1.109 (Pubitemid 38419315)
24. Ahmad M., Saleem S., Ahmad A. S., Yousuf S., Ansari M. A., Khan M. B., Ishrat T., Chaturvedi R. K., Agrawal A. K., Islam F., Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences. Journal of Neurochemistry 2005 93 1 94 104 2-s2.0-20144386944 10.1111/j.1471-4159.2005. 03000.x (Pubitemid 40463519)
25. Ansari M. A., Ahmad A. S., Ahmad M., Salim S., Yousuf S., Ishrat T., Islam F., Selenium protects cerebral ischemia in rat brain mitochondria. Biological Trace Element Research 2004 101 1 73 86 2-s2.0-9144228723 10.1385/BTER:101:1:73 (Pubitemid 39546227)
26. Weinstock M., Shoham S., Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity. Journal of Neural Transmission 2004 111 3 347 366 2-s2.0-1542343843 10.1007/s00702-003-0058-y (Pubitemid 38316610)
27. Singh H. K., Rastogi R. P., Srimal R. C., Dhawan B. N., Effect of bacosides A and B on avoidance responses in rats. Phytotherapy Research 1988 2 2 70 75 2-s2.0-0024237633 (Pubitemid 19038336)
28. Chatterji N., Rastogi R. P., Dhar M. L., Chemical examination of Bacopa monniera Wettst: the constitution of bacoside A. Indian Journal of Chemistry 1965 3 24 29
29. Bhattacharya S. K., Bhattacharya A., Kumar A., Ghosal S., Antioxidant activity of Bacopa monniera in rat frontal cortex, striatum and hippocampus. Phytotherapy Research 2000 14 3 174 179 (Pubitemid 30326010)
30. Chowdhuri D. K., Parmar D., Kakkar P., Shukla R., Seth P. K., Srimal R. C., Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain. Phytotherapy Research 2002 16 7 639 645 2-s2.0-0036846593 10.1002/ptr.1023 (Pubitemid 35334184)
31. Singh H. K., Dhawan B. N., Effect of Bacopa monniera Linn. (Brahmi) extract on avoidance responses in rat. Journal of Ethnopharmacology 1982 5 2 205 214 2-s2.0-0020055896 (Pubitemid 12126680)
32. Dulcy C. P., Singh H. K., Preethi J., Rajan K. E., Standardized extract of Bacopa monniera (BESEB CDRI-08) attenuates contextual associative learning deficits in the aging rat's brain induced by D-galactose. Journal of Neuroscience Research 2012 90 10 2053 2064
33. Russo A., Izzo A. A., Borrelli F., Renis M., Vanella A., Free radical scavenging capacity and protective effect of Bacopa monniera L. on DNA damage. Phytotherapy Research 2003 17 8 870 875 2-s2.0-0141626401 10.1002/ptr.1061 (Pubitemid 37152749)
34. Jyoti A., Sharma D., Neuroprotective role of Bacopa monniera extract against aluminium-induced oxidative stress in the hippocampus of rat brain. NeuroToxicology 2006 27 4 451 457 2-s2.0-33744972325 10.1016/j.neuro.2005.12.007 (Pubitemid 43867775)
35. Tan D., Manchester L. C., Reiter R. J., Qi W., Karbownik M., Calvo J. R., Significance of melatonin in antioxidative defense system: reactions and products. Biological Signals and Receptors 2000 9 3-4 137 159 2-s2.0-0033910011 (Pubitemid 30481268)
36. Reiter R. J., Paredes S. D., Manchester L. C., Tan D., Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin melatonin as an antioxidant R. J. Reiter et al. Critical Reviews in Biochemistry and Molecular Biology 2009 44 4 175 200 2-s2.0-70349577367 10.1080/10409230903044914
37. Ganguly K., Swarnakar S., Induction of matrix metalloproteinase-9 and -3 in nonsteroidal anti-inflammatory drug-induced acute gastric ulcers in mice: regulation by melatonin. Journal of Pineal Research 2009 47 1 43 55 2-s2.0-67649957806 10.1111/j.1600-079X.2009.00687.x
38. Cuzzocrea S., Reiter R. J., Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury. European Journal of Pharmacology 2001 426 1-2 1 10 2-s2.0-0035943414 10.1016/S0014-2999(01)01175-X (Pubitemid 32781781)
39. Rosales-Corral S., Acuna-Castroviejo D., Tan D. X., Accumulation of exogenous amyloid-beta peptide in hippocampal mitochondria causes their dysfunction: a protective role for melatonin. Oxidative Medicine and Cellular Longevity 2012 2012 15 843649 10.1155/2012/843649
40. Singhal N. K., Srivastava G., Patel D. K., Jain S. K., Singh M. P., Melatonin or silymarin reduces maneb- and paraquat-induced Parkinsons disease phenotype in the mouse. Journal of Pineal Research 2011 50 2 97 109 2-s2.0-79951634450 10.1111/j.1600-079X.2010.00819.x
41. Ni C., Tan G., Luo A., Melatonin premedication attenuates isoflurane anesthesia-induced beta-amyloid generation and cholinergic dysfunction in the hippocampus of aged rats. International Journal of Neuroscience 2013 123 4 213 220
42. Agrawal R., Tyagi E., Shukla R., Nath C., Insulin receptor signaling in rat hippocampus: a study in STZ (ICV) induced memory deficit model. European Neuropsychopharmacology 2011 21 3 261 273 2-s2.0-79251628354 10.1016/j.euroneuro.2010.11.009
43. Saxena G., Bharti S., Kamat P. K., Sharma S., Nath C., Melatonin alleviates memory deficits and neuronal degeneration induced by intracerebroventricular administration of streptozotocin in rats. Pharmacology Biochemistry and Behavior 2010 94 3 397 403 2-s2.0-71849106334 10.1016/j.pbb.2009.09.022
44. Uabundit N., Wattanathorn J., Mucimapura S., Ingkaninan K., Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model. Journal of Ethnopharmacology 2010 127 1 26 31 2-s2.0-72449158360 10.1016/j.jep.2009.09.056
45. Morris R., Developments of a water-maze procedure for studying spatial learning in the rat. Journal of Neuroscience Methods 1984 11 1 47 60 2-s2.0-0021173996 10.1016/0165-0270(84)90007-4 (Pubitemid 14088970)
46. Tiwari V., Chopra K., Attenuation of oxidative stress, neuroinflammation, and apoptosis by curcumin prevents cognitive deficits in rats postnatally exposed to ethanol. Psychopharmacology 2012 224 4 519 535
47. Tota S., Hanif K., Kamat P. K., Najmi A. K., Nath C., Role of central angiotensin receptors in scopolamine-induced impairment in memory, cerebral blood flow, and cholinergic function. Psychopharmacology 2012 222 2 185 202 2-s2.0-84857227904 10.1007/s00213-012-2639-7
48. Glowinski J., Iversen L. L., Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. Journal of Neurochemistry 1966 13 8 655 669 2-s2.0-0013939811
49. Ellman G. L., Courtney K. D., Andres V. Jr., Featherstone R. M., A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology 1961 7 2 88 95 2-s2.0-33644811612
50. Green L. C., Wagner D. A., Glogowski J., Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Analytical Biochemistry 1982 126 1 131 138 2-s2.0-0020448709 (Pubitemid 13203451)
51. Deak T., Bellamy C., D'Agostino L. G., Exposure to forced swim stress does not alter central production of IL-1. Brain Research 2003 972 1-2 53 63 2-s2.0-0037449177 10.1016/S0006-8993(03)02485-5 (Pubitemid 36507077)
52. Tyagi E., Agrawal R., Nath C., Shukla R., Cholinergic protection via α 7 nicotinic acetylcholine receptors and PI3K-Akt pathway in LPS-induced neuroinflammation. Neurochemistry International 2010 56 1 135 142 2-s2.0-73449105029 10.1016/j.neuint.2009.09.011
53. Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J., Protein measurement with the Folin phenol reagent. The Journal of Biological Chemistry 1951 193 1 265 275 2-s2.0-71849104860
54. Rai A., Maurya S. K., Khare P., Srivastava A., Bandyopadhyay S., Characterization of developmental neurotoxicity of As, Cd, and Pb mixture: synergistic action of metal mixture in glial and neuronal functions. Toxicological Sciences 2010 118 2 586 601 2-s2.0-78549247841 10.1093/toxsci/kfq266
55. McIntosh L. J., Trush M. A., Troncoso J. C., Increased susceptibility of Alzheimer's disease temporal cortex to oxygen free radical-mediated processes. Free Radical Biology and Medicine 1997 23 2 183 190 2-s2.0-0030910847 10.1016/S0891-5849(96)00573-4 (Pubitemid 27276599)
56. Polidori M. C., Mecocci P., Plasma susceptibility to free radical-induced antioxidant consumption and lipid peroxidation is increased in very old subjects with Alzheimer disease. Journal of Alzheimer's Disease 2002 4 6 517 522 2-s2.0-0036970014 (Pubitemid 36142841)
57. Tripathi D. N., Jena G. B., Effect of melatonin on the expression of Nrf2 and NF- B during cyclophosphamide-induced urinary bladder injury in rat. Journal of Pineal Research 2010 48 4 324 331 2-s2.0-77950648335 10.1111/j.1600-079X.2010.00756.x
58. Negi G., Kumar A., Sharma S. S., Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF- B and Nrf2 cascades. Journal of Pineal Research 2011 50 2 124 131 2-s2.0-79951642115 10.1111/j.1600-079X.2010.00821.x
59. Viji V., Helen A., Inhibition of pro-inflammatory mediators: role of Bacopa monniera (L.) Wettst. Inflammopharmacology 2011 19 5 283 291 2-s2.0-80054878244 10.1007/s10787-010-0046-4
60. Levinthal D. J., DeFranco D. B., Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons. The Journal of Biological Chemistry 2005 280 7 5875 5883 2-s2.0-14044277677 10.1074/jbc.M410771200 (Pubitemid 40280070)
61. Vogelsberg-Ragaglia V., Schuck T., Trojanowski J. Q., Lee V. M.-Y., PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus. Experimental Neurology 2001 168 2 402 412 2-s2.0-0035075793 10.1006/exnr.2001. 7630 (Pubitemid 32289776)
62. Lee J. H., Park S. Y., Shin Y. W., Kim C. D., Lee W. S., Hong K. W., Concurrent administration of cilostazol with donepezil effectively improves cognitive dysfunction with increased neuroprotection after chronic cerebral hypoperfusion in rats. Brain Research 2007 1185 1 246 255 2-s2.0-36448937109 10.1016/j.brainres.2007.09.016 (Pubitemid 350166308)
63. Koh P., Melatonin attenuates decrease of protein phosphatase 2A subunit B in ischemic brain injury. Journal of Pineal Research 2012 52 1 57 61 2-s2.0-83555166114 10.1111/j.1600-079X.2011.00918.x
64. Zhao H. H., Di J., Liu W. S., Involvement of GSK3 and PP2A in ginsenoside Rb1's attenuation of aluminum-induced tau hyperphosphorylation. Behavioural Brain Research 2013 241 228 234
65. Zamzami N., Marchetti P., Castedo M., Decaudin D., Macho A., Hirsch T., Susin S. A., Petit P. X., Mignotte B., Kroemer G., Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. Journal of Experimental Medicine 1995 182 2 367 377 2-s2.0-0029101644 10.1084/jem.182.2.367
66. Jiang X. Z., Song Q., Xu X. P., The effects of Nrf2 gene expression induced by RU486 at different doses on A549 cell damage induced by paraquat. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2012 30 4 268 272
67. Suuronen T., Kolehmainen P., Salminen A., Protective effect of L-Deprenyl against apoptosis induced by okadaic acid in cultured neuronal cells. Biochemical Pharmacology 2000 59 12 1589 1595 2-s2.0-0034111582 10.1016/S0006-2952(00)00282-3 (Pubitemid 30229893)
68. Niture S. K., Jaiswal A. K., Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance. Free Radical Biology and Medicine 2013 57 119 131
69. Li Z., Nickkholgh A., Yi X., Bruns H., Gross M., Hoffmann K., Mohr E., Zorn M., Büchler M. W., Schemmer P., Melatonin protects kidney grafts from ischemia/reperfusion injury through inhibition of NF-kB and apoptosis after experimental kidney transplantation. Journal of Pineal Research 2009 46 4 365 372 2-s2.0-64649083376 10.1111/j.1600-079X.2009.00672.x
70. Mohanty I. R., Maheshwari U., Joseph D., Deshmukh Y., Bacopa monniera protects rat heart against ischaemia-reperfusion injury: role of key apoptotic regulatory proteins and enzymes. Journal of Pharmacy and Pharmacology 2010 62 9 1175 1184 2-s2.0-77955251038 10.1111/j.2042-7158.2010.01155.x
71. Feng Z., Zhang J., Protective effect of melatonin on β -amyloid-induced apoptosis in rat astroglioma c6 cells and its mechanism. Free Radical Biology and Medicine 2004 37 11 1790 1801 2-s2.0-7444246751 10.1016/j.freeradbiomed.2004.08.023 (Pubitemid 39441063)