Okadaic acid (ICV) induced memory impairment in rats: A suitable experimental model to test anti-dementia activity

Brain Research

Volumn 1309, Issue , 2010, Pages 66-74

  Kamat, Pradeep K ^a   Tota, Santoshkumar ^a   Saxena, Gunjan ^a   Shukla, Rakesh ^a   Nath, Chandishwar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Donepezil; Excitotoxicity; Memantine; Memory impairment; Morris water maze; Okadaic acid; Oxidative stress

Indexed keywords

CALCIUM ION; DONEPEZIL; GLUTATHIONE; MALONALDEHYDE; MEMANTINE; NITRITE; NOOTROPIC AGENT; OKADAIC ACID; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DEMENTIA; DRUG MECHANISM; DRUG SCREENING; MALE; MAZE TEST; MEMORY DISORDER; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TASK PERFORMANCE;

ANIMALS; BRAIN; CALCIUM SIGNALING; CHOLINESTERASE INHIBITORS; DEMENTIA; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTATHIONE; INDANS; INJECTIONS, INTRAVENTRICULAR; MALE; MALONDIALDEHYDE; MAZE LEARNING; MEMANTINE; MEMORY; MEMORY DISORDERS; NEUROPSYCHOLOGICAL TESTS; NITRITES; OKADAIC ACID; OXIDATIVE STRESS; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; TREATMENT OUTCOME;

RATTUS;

EID: 72049129673     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.10.064     Document Type: Article

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