Melatonin premedication attenuates isoflurane anesthesia-induced β-amyloid generation and cholinergic dysfunction in the hippocampus of aged rats

International Journal of Neuroscience

Volumn 123, Issue 4, 2013, Pages 213-220

  Ni, Cheng ^a   Tan, Gang ^b   Luo, Ailun ^b   Qian, Min ^a   Tang, Yi ^a   Zhou, Yang ^a   Wang, Jun ^a   Li, Min ^a   Zhang, Yan ^c   Jia, Donglin ^a   Wu, Changyi ^a   Guo, Xiangyang ^a  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

amyloid; Choline acetyltransferase; Hippocampus; Isoflurane; Melatonin

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; CHOLINE ACETYLTRANSFERASE; ISOFLURANE; MELATONIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; AUTONOMIC DYSFUNCTION; CHOLINERGIC DYSFUNCTION; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DENTATE GYRUS; DOSE RESPONSE; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; GRANULE CELL; HEART RATE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; HORMONE BLOOD LEVEL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; NERVE DEGENERATION; NONHUMAN; PREMEDICATION; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; WESTERN BLOTTING;

AMYLOID BETA-PEPTIDES; ANESTHETICS, INHALATION; ANIMALS; ANTIOXIDANTS; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; ISOFLURANE; MALE; MELATONIN; NERVE DEGENERATION; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84875178150     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.3109/00207454.2012.742895     Document Type: Article

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