Melatonin protects kidney grafts from ischemia/reperfusion injury through inhibition of NF-kB and apoptosis after experimental kidney transplantation

Journal of Pineal Research

Volumn 46, Issue 4, 2009, Pages 365-372

  Li, Zhanqing ^a,b   Nickkholgh, Arash ^a   Yi, Xue ^a,b   Bruns, Helge ^a   Gross, Marie Luise ^a   Hoffmann, Katrin ^a   Mohr, Elvira ^a   Zorn, Markus ^a   Büchler, Markus W ^a   Schemmer, Peter ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NORTH CHINA COAL MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; Caspase; INOS; Ischemia reperfusion injury; Kidney transplantation; Melatonin; NF kB; Radical scavenger; Tubular damage

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CREATININE; INDUCIBLE NITRIC OXIDE SYNTHASE; LACTATE DEHYDROGENASE; LIPID HYDROPEROXIDE; MELATONIN; NITROGEN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOWN REGULATION; ENZYME ACTIVITY; EXPERIMENTAL MODEL; GRAFT SURVIVAL; HISTOPATHOLOGY; ISCHEMIC PRECONDITIONING; KIDNEY BIOPSY; KIDNEY FUNCTION; KIDNEY GRAFT; KIDNEY ISCHEMIA; KIDNEY TRANSPLANTATION; KIDNEY TUBULE DAMAGE; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; NEPHRECTOMY; NONHUMAN; OXIDATIVE STRESS; RAT; RENAL PROTECTION; REPERFUSION INJURY; STORAGE TEMPERATURE; UREA NITROGEN BLOOD LEVEL;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; CASPASE 3; HISTOCYTOCHEMISTRY; KAPLAN-MEIERS ESTIMATE; KIDNEY; KIDNEY TRANSPLANTATION; LIPID PEROXIDATION; MALE; MELATONIN; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RANDOM ALLOCATION; RATS; RATS, INBRED LEW; REPERFUSION INJURY; SUPEROXIDE DISMUTASE; TRANSPLANTATION CONDITIONING;

EID: 64649083376     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2009.00672.x     Document Type: Article

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