Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model

Journal of Ethnopharmacology

Volumn 127, Issue 1, 2010, Pages 26-31

  Uabundit, Nongnut ^a   Wattanathorn, Jintanaporn ^b   Mucimapura, Supaporn ^b   Ingkaninan, Kornkanok ^c  

^a THAMMASAT UNIVERSITY   (Thailand)

^b KHON KAEN UNIVERSITY   (Thailand)

^c NARESUAN UNIVERSITY   (Thailand)

Author keywords

AF64A; Alzheimer's disease; Bacopa monnieri; Cognitive enhancing effect; Neuroprotective; Scrophulariaceae

Indexed keywords

BACOPA MONNIERI EXTRACT; DONEPEZIL; ETHYLCHOLINE MUSTARD AZIRIDINIUM;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLINERGIC NERVE CELL; COGNITION; CONTROLLED STUDY; DENTATE GYRUS; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; HIPPOCAMPUS; LATENT PERIOD; MALE; MAZE TEST; MEMORY DISORDER; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; RAT; SPATIAL MEMORY;

ALZHEIMER DISEASE; ANIMALS; BACOPA; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; MALE; MAZE LEARNING; MEDICINE, AYURVEDIC; MEMORY; NEURONS; NEUROPROTECTIVE AGENTS; NOOTROPIC AGENTS; ORGAN SPECIFICITY; PHYTOTHERAPY; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; RANDOM ALLOCATION; RATS; RATS, WISTAR;

ANIMALIA; BACOPA MONNIERI; RATTUS; RATTUS NORVEGICUS; SCROPHULARIACEAE;

EID: 72449158360     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.09.056     Document Type: Article

References (27)

1. Arlt S., Beisiegel U., and Kontush A. Lipid peroxidation in neurodegeneration: new insights into Alzheimer's disease. Current Opinion in Lipidology 13 (2002) 289-294
2. Bhattacharya S.K., Bhattacharya A., Kumar A., and Ghosal S. Antioxidant activity of Bacopa monnieri in rat frontal cortex, striatum and hippocampus. Phytotherapy Research 14 (2000) 174-179
3. Bhattacharya S.K., and Ghosal S. Anxiolytic activity of a standardized extract of Bacopa monnieri an experimental study. Phytomedicine 5 (1998) 77-82
4. Choi Y.T., Jung C.H., Lee S.R., Bae J.H., Baek W.K., Suh M.H., Park J., Park C.W., and Suh S.I. The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induce neurotoxicity in cultured hippocampal neurons. Life Science 70 (2001) 603-614
5. Chowdhuri D.K., Parmar D., Kakkar P., Shukla R., Seth P.K., and Srimal R.C. Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain. Phytotherapy Research 16 (2002) 639-645
6. Chopra R.N., Nayar S.L., and Chopra I.C. Glossary of Indian Medicinal Plants (1956), Council of Scientific and Industrial Research, New Delhi
7. Desgranges B., Baron J.C., de la Sayette V., Petit-Taboue M.C., Benali K., Landeau B., Lechevalier B., and Eustache F. The neural substrates of memory systems impairment in Alzheimer's disease. A PET study of resting brain glucose utilization. Brain 121 (1998) 611-631
8. Emilien G., Beyreuther K., Masters C.L., and Maloteaux J.M. Prospects for pharmacological intervention in Alzheimer disease. Archives in Neurology 57 (2000) 454-459
9. Francis P.T., Palmer A.M., Snape M., and Wilcock G.K. The cholinergic hypothesis of Alzheimer's disease: a review of progress. Journal of Neurology, Neurosurgery & Psychiatry 66 (1999) 137-147
10. Guidi I., Galimberti D., Lonati S., Novembrino C., Bamonti F., Tiriticco M., Fenoglio C., Venturelli E., Baron P., Bresolin N., and Scarpini E. Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease. Neurobiology of Aging 27 (2006) 262-269
11. Hanin I. The AF64A model of cholinergic hypofunction: an update. Life Science 58 (1996) 1955-1964
12. Kant G.J., Wylie R.M., Vasilakis A.A., and Ghosh S. Effects of triazolam and diazepam on learning and memory as assessed using a water maze. Pharmacology Biochemistry and Behavior 53 (1996) 317-322
13. Kapoor R., Srivastava S., and Kakkar P. Bacopa monnieri modulates antioxidant responses in brain and kidney of diabetic rats. Environmental Toxicology and Pharmacology 27 (2009) 62-69
14. Kishore K., and Singh M. Effect of bacosides, alcoholic extract of Bacopa monnieri Linn. (Brahmi), on experimental amnesia in mice. Indian Journal of Experimental Biology 43 (2005) 640-645
15. Kontush K., and Schekatolina S. Vitamin E in neurodegenerative disorders: Alzheimer's disease. Annual New York Academy of Science 1031 (2004) 249-262
16. Lahiri D.K., Rogers J.T., Greig N.H., and Sambamurti K. Rationale for the development of cholinesterase inhibitors as anti-Alzheimer agents. Current Pharmaceutical Design 10 (2004) 3111-3119
17. Nicolakakis N., Aboulkassim T., Ongali B., Lecrux C., Fernandes P., Rosa-Neto P., Tong X.K., and Hamel E. Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist. Journal of Neuroscience 28 (2008) 9287-9296
18. Ono K., Hamaguchi T., Naiki H., and Yamada M. Anti-amyloidogenic effects of antioxidants: implications for the prevention and therapeutics of Alzheimer's disease. Biochimica Biophysica Acta 1762 (2006) 575-586
19. Ono K., Yoshiike Y., Takashima A., Hasegawa K., Naiki H., and Yamada M. Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease. Journal of Neurochemistry 87 (2003) 172-181
20. Phrompittayarat W., Putalun W., Tanaka H., Jetiyanon K., Wittaya-areekul S., and Ingkaninan K. Comparison of various extraction methods of Bacopa monnieri. Naresuan University Journal 15 (2007) 29-34
21. Phrompittayarat W., Wittaya-areekul S., Jetiyanon K., Putalun W., Tanaka H., and Ingkaninan K. Determination of saponin glycosides in Bacopa monnieri by reversed phase high performance liquid chromatography. Srinakharinwirot Journal of Pharmaceutical Sciences 2 (2007) 26-32
22. Reis H.J., Guatimosim C., Paquet M., Santos M., Ribeiro F.M., Kummer A., Schenatto G., Vsalgado J.V., Vieira L.B., Teixeira A.L., and Palotás A. Neuro-transmitters in the central nervous system and their implication in learning and memory processes. Current Medicinal Chemistry 16 (2009) 796-840
23. Russo A., and Borrelli F. Bacopa monnieri, a reputed nootropic plant: an overview. Phytomedicine 12 (2005) 305-317
24. Saraf M.K., Prabhakar S., and Anand A. Bacopa monnieri alleviates N(omega)-nitro-l-arginine arginine-induced but not MK-801-induced amnesia: a mouse Morris watermaze study. Neuroscience 160 (2009) 149-155
25. Tong X.K., Nicolakakis N., Fernandes P., Ongali B., Brouillette J., Quirion R., and Hamel E. Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice. Neurobiology of Disease 35 (2009) 406-414
26. White K.G., and Ruske A.C. Memory deficits in Alzheimer's disease: the encoding hypothesis and cholinergic function. Psychonomic Bulletin and Review 9 (2002) 426-437
27. Zandi P.P., Anthony J.C., Khachaturian A.S., Stone S.V., Gustafson D., Tschanz J.T., Norton M.C., Welsh-Bohmer K.A., Breitner J.C., and Cache County Study Group. Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study. Archives in Neurology 61 (2004) 82-88