-
1
-
-
0026326710
-
A review of the pharmacology of selegiline
-
Heinonen EH and Lammintausta R, A review of the pharmacology of selegiline. Acta Neurol Scand Suppl136: 44-59, 1991.
-
(1991)
Acta Neurol Scand
, Issue.136 SUPPL.
, pp. 44-59
-
-
Heinonen, E.H.1
Lammintausta, R.2
-
2
-
-
0027530638
-
Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
-
Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med. 328:1993;176-183.
-
(1993)
N Engl J Med
, vol.328
, pp. 176-183
-
-
-
3
-
-
0030967165
-
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study
-
Sano M., Ernesto C., Thomas R.G., Klauber M.R., Schafer K., Grundman M., Woodbury P., Growdon J., Cotman C.W., Pfeiffer E., Schneider L.S., Thal L.J. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. N Engl J Med. 336:1997;1216-1222.
-
(1997)
N Engl J Med
, vol.336
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
Klauber, M.R.4
Schafer, K.5
Grundman, M.6
Woodbury, P.7
Growdon, J.8
Cotman, C.W.9
Pfeiffer, E.10
Schneider, L.S.11
Thal, L.J.12
-
4
-
-
0029731378
-
Modulation of gene expression rather than monoamine oxidase inhibition: (-)-Deprenyl-related compounds in controlling neurodegeneration
-
Tatton WG and Chalmers-Redman RM, Modulation of gene expression rather than monoamine oxidase inhibition: (-)-Deprenyl-related compounds in controlling neurodegeneration. Neurology 47(Suppl 3): S171-S183, 1996.
-
(1996)
Neurology
, vol.47
, Issue.3 SUPPL.
-
-
Tatton, W.G.1
Chalmers-Redman, R.M.2
-
5
-
-
77956767839
-
Antiapoptotic actions of monoamine oxidase B inhibitors
-
Paterson I.A., Tatton W.G. Antiapoptotic actions of monoamine oxidase B inhibitors. Adv Pharmacol. 42:1998;312-315.
-
(1998)
Adv Pharmacol
, vol.42
, pp. 312-315
-
-
Paterson, I.A.1
Tatton, W.G.2
-
6
-
-
0031596692
-
The neuroprotective and neuronal rescue effects of (-)-deprenyl
-
Magyar K., Szende B., Lengyel J., Tarczali J., Szatmary I. The neuroprotective and neuronal rescue effects of (-)-deprenyl. J Neural Transm Suppl. 52:1998;109-123.
-
(1998)
J Neural Transm Suppl
, vol.52
, pp. 109-123
-
-
Magyar, K.1
Szende, B.2
Lengyel, J.3
Tarczali, J.4
Szatmary, I.5
-
7
-
-
0031890109
-
Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: Time course and modification by (-)-deprenyl
-
Wadia J.S., Chalmers-Redman R.M., Ju W.J., Carlile G.W., Phillips J.L., Fraser A.D., Tatton W.G. Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal Time course and modification by (-)-deprenyl . J Neurosci. 18:1998;932-947.
-
(1998)
J Neurosci
, vol.18
, pp. 932-947
-
-
Wadia, J.S.1
Chalmers-Redman, R.M.2
Ju, W.J.3
Carlile, G.W.4
Phillips, J.L.5
Fraser, A.D.6
Tatton, W.G.7
-
8
-
-
0031886449
-
Deprenyl and desmethylselegiline protect mesencephalic neurons from toxicity induced by glutathione depletion
-
Mytilineou C., Leonardi E.K., Radcliffe P., Heinonen E.H., Han S.K., Werner P., Cohen P., Olanow C.W. Deprenyl and desmethylselegiline protect mesencephalic neurons from toxicity induced by glutathione depletion. J Pharmacol Exp Ther. 284:1998;700-706.
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 700-706
-
-
Mytilineou, C.1
Leonardi, E.K.2
Radcliffe, P.3
Heinonen, E.H.4
Han, S.K.5
Werner, P.6
Cohen, P.7
Olanow, C.W.8
-
9
-
-
0031914155
-
R-Deprenyl and R-2-heptyl-N-methylpropargylamine prevent apoptosis in cerebellar granule neurons induced by cytosine arabinoside but not low extracellular potassium
-
Paterson I.A., Zhang D., Warrington R.C., Boulton A.A. R-Deprenyl and R-2-heptyl-N-methylpropargylamine prevent apoptosis in cerebellar granule neurons induced by cytosine arabinoside but not low extracellular potassium. J Neurochem. 70:1998;515-523.
-
(1998)
J Neurochem
, vol.70
, pp. 515-523
-
-
Paterson, I.A.1
Zhang, D.2
Warrington, R.C.3
Boulton, A.A.4
-
10
-
-
0028272055
-
(-)-Deprenyl alters the time course of death of axotomized facial motoneurons and the hypertrophy of neighboring astrocytes in immature rats
-
Ju W.Y., Holland D.P., Tatton W.G. (-)-Deprenyl alters the time course of death of axotomized facial motoneurons and the hypertrophy of neighboring astrocytes in immature rats. Exp Neurol. 126:1994;233-246.
-
(1994)
Exp Neurol
, vol.126
, pp. 233-246
-
-
Ju, W.Y.1
Holland, D.P.2
Tatton, W.G.3
-
11
-
-
0030994173
-
Selegiline treatment after transient global ischemia in gerbils enhances the survival of CA1 pyramid cells in the hippocampus
-
Lahtinen H., Koistinaho J., Kauppinen R., Haapalinna A., Keinänen R., Sivenius J. Selegiline treatment after transient global ischemia in gerbils enhances the survival of CA1 pyramid cells in the hippocampus. Brain Res. 757:1997;260-267.
-
(1997)
Brain Res
, vol.757
, pp. 260-267
-
-
Lahtinen, H.1
Koistinaho, J.2
Kauppinen, R.3
Haapalinna, A.4
Keinänen, R.5
Sivenius, J.6
-
12
-
-
0030300164
-
(-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase
-
Tatton W.G., Wadia J.S., Ju W.Y., Chalmers-Redman R.M., Tatton N.A. (-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase. J Neural Transm Suppl. 48:1996;45-59.
-
(1996)
J Neural Transm Suppl
, vol.48
, pp. 45-59
-
-
Tatton, W.G.1
Wadia, J.S.2
Ju, W.Y.3
Chalmers-Redman, R.M.4
Tatton, N.A.5
-
13
-
-
0032512125
-
Distinct mode of apoptosis induced by genotoxic agent etoposide and serum withdrawal in neuroblastoma cells
-
Solovyan V., Bezvenyuk Z., Huotari V., Tapiola T., Suuronen T., Salminen A. Distinct mode of apoptosis induced by genotoxic agent etoposide and serum withdrawal in neuroblastoma cells. Mol Brain Res. 62:1998;43-55.
-
(1998)
Mol Brain Res
, vol.62
, pp. 43-55
-
-
Solovyan, V.1
Bezvenyuk, Z.2
Huotari, V.3
Tapiola, T.4
Suuronen, T.5
Salminen, A.6
-
14
-
-
0027226219
-
Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
-
Brewer G.J., Torricelli J.R., Evege E.K., Price P.J. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J Neurosci Res. 35:1993;567-576.
-
(1993)
J Neurosci Res
, vol.35
, pp. 567-576
-
-
Brewer, G.J.1
Torricelli, J.R.2
Evege, E.K.3
Price, P.J.4
-
15
-
-
0001607156
-
Preparation of primary cultures of mouse (rat) cerebullar granule cells
-
A. Shahar, J. de Vellis, A. Vernadalis, & B. Haber. New York: AR Liss
-
Schousboe A., Meier E., Drejer J., Hertz L. Preparation of primary cultures of mouse (rat) cerebullar granule cells. Shahar A., de Vellis J., Vernadalis A., Haber B. A Dissection and Tissue Culture Manual of the Nervous System. 1989;203-206 AR Liss, New York.
-
(1989)
A Dissection and Tissue Culture Manual of the Nervous System
, pp. 203-206
-
-
Schousboe, A.1
Meier, E.2
Drejer, J.3
Hertz, L.4
-
16
-
-
0032501056
-
Expression of transcriptional repressor protein mSin3A but not mSin3B is induced during neuronal apoptosis
-
Korhonen P., Tapiola T., Suuronen T., Salminen A. Expression of transcriptional repressor protein mSin3A but not mSin3B is induced during neuronal apoptosis. Biochem Biophys Res Commun. 252:1998;274-277.
-
(1998)
Biochem Biophys Res Commun
, vol.252
, pp. 274-277
-
-
Korhonen, P.1
Tapiola, T.2
Suuronen, T.3
Salminen, A.4
-
17
-
-
0029954311
-
Potassium deprivation-induced apoptosis of cerebullar granule neurons: A sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species
-
Schulz J.B., Weller M., Klockgether T. Potassium deprivation-induced apoptosis of cerebullar granule neurons A sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species . J Neurosci. 16:1996;4696-4706.
-
(1996)
J Neurosci
, vol.16
, pp. 4696-4706
-
-
Schulz, J.B.1
Weller, M.2
Klockgether, T.3
-
18
-
-
0027946686
-
Altered gene expression in neurons during programmed cell death: Identification of c-jun as necessary for neuronal apoptosis
-
Estus S., Zaks W., Freeman R., Gruda M., Bravo R., Johnson E.M. Jr. Altered gene expression in neurons during programmed cell death Identification of c-jun as necessary for neuronal apoptosis . J Cell Biol. 127:1994;1717-1727.
-
(1994)
J Cell Biol
, vol.127
, pp. 1717-1727
-
-
Estus, S.1
Zaks, W.2
Freeman, R.3
Gruda, M.4
Bravo, R.5
Johnson E.M., Jr.6
-
19
-
-
0028314235
-
Etoposide induces programmed death in neurons cultured from the fetal rat central nervous system
-
Nakajima M., Kashiwagi K., Ohta J., Furukawa S., Hayashi K., Kawashima T., Hayashi Y. Etoposide induces programmed death in neurons cultured from the fetal rat central nervous system. Brain Res. 641:1994;350-352.
-
(1994)
Brain Res
, vol.641
, pp. 350-352
-
-
Nakajima, M.1
Kashiwagi, K.2
Ohta, J.3
Furukawa, S.4
Hayashi, K.5
Kawashima, T.6
Hayashi, Y.7
-
20
-
-
0031941563
-
Okadaic acid -induced apoptosis in neuronal cells: Evidence for an abortive mitotic attempt
-
Nuydens R., de Jong M., Van Den Kieboom G., Heers C., Dispersyn G., Cornelissen F., Nuyens R., Borgers M., Geerts H. Okadaic acid -induced apoptosis in neuronal cells Evidence for an abortive mitotic attempt . J Neurochem. 70:1998;1124-1133.
-
(1998)
J Neurochem
, vol.70
, pp. 1124-1133
-
-
Nuydens, R.1
De Jong, M.2
Van Den Kieboom, G.3
Heers, C.4
Dispersyn, G.5
Cornelissen, F.6
Nuyens, R.7
Borgers, M.8
Geerts, H.9
-
21
-
-
0032080868
-
Activation of caspase-3 and apoptosis in cerebellar granule cells
-
Marks N., Berg M.J., Guidotti A., Saito M. Activation of caspase-3 and apoptosis in cerebellar granule cells. J Neurosci Res. 52:1998;334-341.
-
(1998)
J Neurosci Res
, vol.52
, pp. 334-341
-
-
Marks, N.1
Berg, M.J.2
Guidotti, A.3
Saito, M.4
-
22
-
-
0024595042
-
Re-examination and further development of a precise and rapid dye method for measuring cell growth/ cell kill
-
Hansen M.B., Nielsen S.E., Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/ cell kill. J Immunol Methods. 119:1989;203-210.
-
(1989)
J Immunol Methods
, vol.119
, pp. 203-210
-
-
Hansen, M.B.1
Nielsen, S.E.2
Berg, K.3
-
23
-
-
0029175202
-
Calcium, free radicals, and excitotoxic neuronal death in primary cell culture
-
Mattson M.P., Barger S.W., Begley J.G., Mark R.J. Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cells Biol. 46:1995;187-216.
-
(1995)
Methods Cells Biol
, vol.46
, pp. 187-216
-
-
Mattson, M.P.1
Barger, S.W.2
Begley, J.G.3
Mark, R.J.4
-
24
-
-
0032530577
-
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: Evidence for a MAP kinase-dependent mechanism
-
Runden E., Seglen P.O., Haug F.M., Ottersen O.P., Wieloch T., Shamloo M., Laake J. Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures Evidence for a MAP kinase-dependent mechanism . J Neurosci. 18:1998;7296-7305.
-
(1998)
J Neurosci
, vol.18
, pp. 7296-7305
-
-
Runden, E.1
Seglen, P.O.2
Haug, F.M.3
Ottersen, O.P.4
Wieloch, T.5
Shamloo, M.6
Laake, J.7
-
25
-
-
0025181418
-
Okadaic acid: A new probe for the study of cellular regulation
-
Cohen P., Holmes C.F., Tsukitani Y. Okadaic acid A new probe for the study of cellular regulation . Trends Biochem Sci. 15:1990;98-102.
-
(1990)
Trends Biochem Sci
, vol.15
, pp. 98-102
-
-
Cohen, P.1
Holmes, C.F.2
Tsukitani, Y.3
-
26
-
-
0032535169
-
Role of PP2A in intracellular signal transduction pathways
-
Schonthal A.H. Role of PP2A in intracellular signal transduction pathways. Front Biosci. 3:1998;D1262-D1273.
-
(1998)
Front Biosci
, vol.3
, pp. 1262-D1273
-
-
Schonthal, A.H.1
-
27
-
-
0028786849
-
Paired helical filament-like phosphorylation of tau, deposition of β/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A
-
Arendt T., Holzer M., Fruth R., Bruckner M.K., Gärtner U. Paired helical filament-like phosphorylation of tau, deposition of β/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A. Neuroscience. 69:1995;691-698.
-
(1995)
Neuroscience
, vol.69
, pp. 691-698
-
-
Arendt, T.1
Holzer, M.2
Fruth, R.3
Bruckner, M.K.4
Gärtner, U.5
-
28
-
-
0032544268
-
Apoptotic pathways: The roads to ruin
-
Green D.R. Apoptotic pathways The roads to ruin . Cell. 94:1998;695-698.
-
(1998)
Cell
, vol.94
, pp. 695-698
-
-
Green, D.R.1
-
29
-
-
0029959882
-
Apoptosis: Molecular regulation of cell death
-
Hale A.J., Smith C.A., Sutherland L.C., Stoneman V.E., Longthorne V.L., Culhane A.C., Williams G.T. Apoptosis Molecular regulation of cell death . Eur J Biochem. 236:1996;1-26.
-
(1996)
Eur J Biochem
, vol.236
, pp. 1-26
-
-
Hale, A.J.1
Smith, C.A.2
Sutherland, L.C.3
Stoneman, V.E.4
Longthorne, V.L.5
Culhane, A.C.6
Williams, G.T.7
-
31
-
-
0032544721
-
Okadaic acid -induced apoptosis of HL60 leukemia cells is preceded by destabilization of bcl-2 mRNA and downregulation of bcl-2 protein
-
Riordan F.A., Foroni L., Hoffbrand V., Mehta A.B., Wickremasinghe R.G. Okadaic acid -induced apoptosis of HL60 leukemia cells is preceded by destabilization of bcl-2 mRNA and downregulation of bcl-2 protein. FEBS Lett. 435:1998;195-198.
-
(1998)
FEBS Lett
, vol.435
, pp. 195-198
-
-
Riordan, F.A.1
Foroni, L.2
Hoffbrand, V.3
Mehta, A.B.4
Wickremasinghe, R.G.5
-
32
-
-
0030873361
-
Apoptosis of human myeloid leukemia cells induced by an inhibitor of protein phosphatases (okadaic acid) is prevented by Bcl-2 and Bcl-X(L)
-
Benito A., Lerga A., Silva M., Leon J., Fernandez-Luna J.L. Apoptosis of human myeloid leukemia cells induced by an inhibitor of protein phosphatases (okadaic acid) is prevented by Bcl-2 and Bcl-X(L). Leukemia. 11:1997;940-944.
-
(1997)
Leukemia
, vol.11
, pp. 940-944
-
-
Benito, A.1
Lerga, A.2
Silva, M.3
Leon, J.4
Fernandez-Luna, J.L.5
-
33
-
-
0031918742
-
The mitochondrial death/life regulator in apoptosis and necrosis
-
Kroemer G., Dallaporta B., Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol. 60:1998;619-642.
-
(1998)
Annu Rev Physiol
, vol.60
, pp. 619-642
-
-
Kroemer, G.1
Dallaporta, B.2
Resche-Rigon, M.3
-
34
-
-
0027941312
-
(-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis
-
Tatton W.G., Ju W.Y., Holland D.P., Tai C., Kwan M. (-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis. J Neurochem. 63:1994;1572-1575.
-
(1994)
J Neurochem
, vol.63
, pp. 1572-1575
-
-
Tatton, W.G.1
Ju, W.Y.2
Holland, D.P.3
Tai, C.4
Kwan, M.5
-
35
-
-
0030916669
-
The proto-oncogene Bcl-2 and its role in regulating apoptosis
-
Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med. 3:1997;614-620.
-
(1997)
Nat Med
, vol.3
, pp. 614-620
-
-
Kroemer, G.1
|