S-Adenosyl-Homocysteine Is a Weakly Bound Inhibitor for a Flaviviral Methyltransferase

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Chen, Hui ^a   Zhou, Bing ^b   Brecher, Matthew ^a   Banavali, Nilesh ^a,c   Jones, Susan A ^a   Li, Zhong ^a   Zhang, Jing ^a   Nag, Dilip ^a   Kramer, Laura D ^a,c   Ghosh, Arun K ^b   Li, Hongmin ^a,c  

^a WADSWORTH CENTER   (United States)

^b PURDUE UNIVERSITY   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DERIVATIVE; GRL 001 12; GRL 014 11; GRL 015 11; GRL 016 11; METHYLTRANSFERASE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; SINEFUNGIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME INHIBITION; FLAVIVIRUS; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NONHUMAN; STATIC ELECTRICITY; VIROGENESIS;

ADENOSINE; CELL LINE; ENZYME INHIBITORS; FLAVIVIRUS; HUMANS; METHYLTRANSFERASES; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; S-ADENOSYLHOMOCYSTEINE; WEST NILE VIRUS;

EID: 84885159412     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076900     Document Type: Article

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