A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation

Journal of Controlled Release

Volumn 171, Issue 1, 2013, Pages 38-47

  Sinclair, S Michael ^a   Bhattacharyya, Jayanta ^a   McDaniel, Jonathan R ^a   Gooden, David M ^b   Gopalaswamy, Ramesh ^b   Chilkoti, Ashutosh ^a   Setton, Lori A ^a,c  

^a 136 Hudson Hall ^*  (United States)

^b DUKE UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Conjugate; Curcumin; Drug depot; Elastin like polypeptide; Neuroinflammation; Sustained release

Indexed keywords

BIOPOLYMERS; ELASTIN; GLYCOPROTEINS;

CONJUGATE; CURCUMIN; DRUG DEPOT; ELASTIN-LIKE POLYPEPTIDES; NEUROINFLAMMATION; SUSTAINED RELEASE;

POLYPEPTIDES;

BIOMATERIAL; BIOPOLYMER; CARBAMIC ACID; CURCUMIN; DRUG CARRIER; ELASTIN; POLYPEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CELL TYPE; CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MONOCYTE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PHASE TRANSITION; PLASMA; PRIORITY JOURNAL; SCIATIC NERVE; SUSTAINED DRUG RELEASE;

CONJUGATE; CURCUMIN; DRUG DEPOT; ELASTIN-LIKE POLYPEPTIDE; NEUROINFLAMMATION; SUSTAINED RELEASE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE, TUMOR; CURCUMIN; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; ELASTIN; FEMALE; GENETIC ENGINEERING; HOT TEMPERATURE; HUMANS; INFLAMMATION; INTERVERTEBRAL DISC DISPLACEMENT; MICE; MICE, INBRED C57BL; PEPTIDES; SCIATIC NERVE; U937 CELLS;

EID: 84885106645     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.06.032     Document Type: Article

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