Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 14, 2004, Pages 3871-3883

  Adams, Brian K ^a   Ferstl, Eva M ^a   Davis, Matthew C ^a   Herold, Marike ^a   Kurtkaya, Serdar ^a   Camalier, Richard F ^b   Hollingshead, Melinda G ^b   Kaur, Gurmeet ^b   Sausville, Edward A ^b   Rickles, Frederick R ^c   Snyder, James P ^a   Liotta, Dennis C ^a   Shoji, Mamoru ^a  

^a EMORY UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

3D quantitative structure relationship (QSAR); Anti angiogenesis properties; Anti cancer agent in vitro and in vivo; Synthetic curcumin analogs

Indexed keywords

1,5 BIS(2 ACETYLPHENYL)PENTA 1,4 DIEN 3 ONE; 1,5 BIS(2 HYDROXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1,5 BIS(2 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1,5 BIS(3 HYDROXYPHENYL)PENTA 1,4 DIEN 3 ONE; 2,6 BIS(4 HYDROXYPHENYL)PENTA 1,4 DIEN 3 ONE; 3,5 BIS(2 FLUOROBENZYLIDENE)PIPERIDIN 4 ONE; 3,5 BIS(2 HYDROXYBENZYLIDENE) 1 METHYL 4 PIPERIDONE; 3,5 BIS(2 HYDROXYBENZYLIDENE)TETRAHYDRO 4H PYRAN 4 ONE; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CISPLATIN; CURCUMIN; FUMAGILLOL CHLOROACETYLCARBAMATE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER REGRESSION; CELL LINE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; FOLLOW UP; HUMAN; HUMAN CELL; MAXIMUM TOLERATED DOSE; MOUSE; NONHUMAN; NUDE MOUSE; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TUMOR VOLUME;

ANGIOGENESIS INHIBITORS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CURCUMIN; DRUG EVALUATION, PRECLINICAL; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

MUS MUSCULUS;

EID: 2942726181     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.05.006     Document Type: Article

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