메뉴 건너뛰기




Volumn 21, Issue 3, 1996, Pages 271-277

Herniated lumbar intervertebral discs spontaneously produce matrix metalloproteinases, nitric oxide, interleukin-6, and prostaglandin E2

Author keywords

cytokines; degeneration; intervertebral disc; metalloproteinases; nitric oxide; prostaglandin; radiculopathy

Indexed keywords

CYTOKINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; METALLOPROTEINASE; NITRIC OXIDE; PROSTAGLANDIN E2; SUBSTANCE P; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030020183     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-199602010-00003     Document Type: Article
Times cited : (582)

References (49)
  • 1
    • 0022379461 scopus 로고
    • Gradual disc prolapse
    • Adams MA, Hutton WC. Gradual disc prolapse. Spine 1985;10:524-31.
    • (1985) Spine , vol.10 , pp. 524-531
    • Adams, M.A.1    Hutton, W.C.2
  • 2
    • 0017199997 scopus 로고
    • Qualitative changes with age of proteoglycans of human lumbar discs
    • Adams P, Muir H. Qualitative changes with age of proteoglycans of human lumbar discs. Ann Rheum Dis 1976;35: 289-96.
    • (1976) Ann Rheum Dis , vol.35 , pp. 289-296
    • Adams, P.1    Muir, H.2
  • 3
    • 0026504886 scopus 로고
    • The synovial activation of chondrocytes: Evidence for complex cytokine interactions involving a possible novel factor
    • Bandara G, Lin CW, Georgescu HI, Evans CH. The synovial activation of chondrocytes: Evidence for complex cytokine interactions involving a possible novel factor. Biochim Biophys Acta 1992;1134:309-18.
    • (1992) Biochim Biophys Acta , vol.1134 , pp. 309-318
    • Bandara, G.1    Lin, C.W.2    Georgescu, H.I.3    Evans, C.H.4
  • 4
    • 0000393436 scopus 로고
    • Auto-immune response to nucleus pulposus in the rabbit
    • Bobechko WP, Hirsch C. Auto-immune response to nucleus pulposus in the rabbit. J Bone Joint Surg [Br] 1965;47: 574-80.
    • (1965) J Bone Joint Surg [Br] , vol.47 , pp. 574-580
    • Bobechko, W.P.1    Hirsch, C.2
  • 5
    • 0001409679 scopus 로고
    • The intervertebral disc: Its microscopic anatomy and pathology: Part I. Anatomy, development, and physiology
    • Coventry MB, Ghormley RK, Kernohan JW. The intervertebral disc: Its microscopic anatomy and pathology: Part I. Anatomy, development, and physiology. J Bone Joint Surg 1945;24:105-12.
    • (1945) J Bone Joint Surg , vol.24 , pp. 105-112
    • Coventry, M.B.1    Ghormley, R.K.2    Kernohan, J.W.3
  • 6
    • 0001409678 scopus 로고
    • The intervertebral disc: Its microscopic anatomy and pathology: Part II. Changes in the intervertebral disc concomitant with age
    • Coventry MB, Ghormley RK, Kernohan JW. The intervertebral disc: Its microscopic anatomy and pathology: Part II. Changes in the intervertebral disc concomitant with age. J Bone Joint Surg 1945;27:233-47.
    • (1945) J Bone Joint Surg , vol.27 , pp. 233-247
    • Coventry, M.B.1    Ghormley, R.K.2    Kernohan, J.W.3
  • 7
    • 0021368208 scopus 로고
    • Epidemiology of musculoskeletal impairments and associated disability
    • Cunningham LS, Kelsey JL. Epidemiology of musculoskeletal impairments and associated disability. Am J Public Health 1984;74:574-9.
    • (1984) Am J Public Health , vol.74 , pp. 574-579
    • Cunningham, L.S.1    Kelsey, J.L.2
  • 8
    • 0023222288 scopus 로고
    • Descriptive epidemiology of low back pain and its related medical care in the United States
    • Deyo RA, Tsui-Wu YJ. Descriptive epidemiology of low back pain and its related medical care in the United States. Spine 1987;12:264-8.
    • (1987) Spine , vol.12 , pp. 264-268
    • Deyo, R.A.1    Tsui-Wu, Y.J.2
  • 9
    • 0343485984 scopus 로고
    • The role of the chondrocyte microenvironment in the degradation of cartilage matrix
    • Verbruggen G, Veys EM, eds. Amsterdam: Elsevier
    • Dingle JT, Knight CG. The role of the chondrocyte microenvironment in the degradation of cartilage matrix. In: Verbruggen G, Veys EM, eds. Degenerative Joints, Vol 2. Amsterdam: Elsevier, 1985;69-77.
    • (1985) Degenerative Joints , vol.2 , pp. 69-77
    • Dingle, J.T.1    Knight, C.G.2
  • 10
    • 0021783959 scopus 로고
    • The ruptured intervertebral disc: Follow-up report on the first case fifty years after recognition of the syndrome and its surgical significance
    • Frymoyer JW, Donaghy RM. The ruptured intervertebral disc: Follow-up report on the first case fifty years after recognition of the syndrome and its surgical significance. J Bone Joint Surg [Am] 1985;67:1113-6.
    • (1985) J Bone Joint Surg [Am] , vol.67 , pp. 1113-1116
    • Frymoyer, J.W.1    Donaghy, R.M.2
  • 12
    • 0021174673 scopus 로고
    • Spine radiographs in patients with lowback pain: An epidemiological study in men
    • Frymoyer JW, Newberg A, Pope MH, et al. Spine radiographs in patients with lowback pain: An epidemiological study in men. J Bone Joint Surg [Am] 1984;66:1048-55.
    • (1984) J Bone Joint Surg [Am] , vol.66 , pp. 1048-1055
    • Frymoyer, J.W.1    Newberg, A.2    Pope, M.H.3
  • 13
    • 0027434230 scopus 로고
    • Neutral proteinases in human intervertebral disc: Role in degeneration and probable origin
    • Fujita K, Nakagawa T, Hirabayashi K, Nagai Y. Neutral proteinases in human intervertebral disc: Role in degeneration and probable origin. Spine 1993;18:1766-73.
    • (1993) Spine , vol.18 , pp. 1766-1773
    • Fujita, K.1    Nakagawa, T.2    Hirabayashi, K.3    Nagai, Y.4
  • 14
    • 0016654064 scopus 로고
    • Autoimmunity in degenerative disc disease of the lumbar spine
    • Gertzbein SD, Tile M, Gross A, et al. Autoimmunity in degenerative disc disease of the lumbar spine. Orthop Clin North Am 1975;6:67-73.
    • (1975) Orthop Clin North Am , vol.6 , pp. 67-73
    • Gertzbein, S.D.1    Tile, M.2    Gross, A.3
  • 15
    • 0016547277 scopus 로고
    • A rapid sensitive collagenase assay
    • Gisslow MT, McBride BC. A rapid sensitive collagenase assay. Anal Biochem 1975;68:70-8.
    • (1975) Anal Biochem , vol.68 , pp. 70-78
    • Gisslow, M.T.1    McBride, B.C.2
  • 16
    • 0014578924 scopus 로고
    • Age-related variations in protein-polysaccharides from human nucleus pulposus, anulus fibrosus, and costal cartilage
    • Gower WE, Pegrini V. Age-related variations in protein-polysaccharides from human nucleus pulposus, anulus fibrosus, and costal cartilage. J Bone Joint Surg [Am] 1969;51: 1154-62.
    • (1969) J Bone Joint Surg [Am] , vol.51 , pp. 1154-1162
    • Gower, W.E.1    Pegrini, V.2
  • 18
    • 0343921764 scopus 로고
    • The role of a novel serine protease in mammalian articular cartilage degradation
    • Hecht AC, Riviere L, Wright M, et al. The role of a novel serine protease in mammalian articular cartilage degradation (abstract). Trans Orthop Res Soc 1994;19:50.
    • (1994) Trans Orthop Res Soc , vol.19 , pp. 50
    • Hecht, A.C.1    Riviere, L.2    Wright, M.3
  • 19
    • 0343050132 scopus 로고
    • The role of nitric oxide in IL-1 and TNF-α induced inhibition of proteoglycan synthesis in human articular cartilage
    • Hickery MS, Palmer RMJ, Charles IG, Moncada S, Bayliss MT. The role of nitric oxide in IL-1 and TNF-α induced inhibition of proteoglycan synthesis in human articular cartilage. Trans Orthop Res Soc 1994;19:77.
    • (1994) Trans Orthop Res Soc , vol.19 , pp. 77
    • Hickery, M.S.1    Palmer, R.M.J.2    Charles, I.G.3    Moncada, S.4    Bayliss, M.T.5
  • 20
    • 0014258939 scopus 로고
    • Abnormal myelograms in asymptomatic patients
    • Hitselberger WE, Witten RM. Abnormal myelograms in asymptomatic patients. J Neurosurg 1968;28:204-6.
    • (1968) J Neurosurg , vol.28 , pp. 204-206
    • Hitselberger, W.E.1    Witten, R.M.2
  • 21
    • 0025368091 scopus 로고
    • Comparison of the effect of interleukin-6 and interleukin-1 on collagenase and proteoglycan production by chondrocytes
    • Kandel RA, Petelycky M, Dinarello CA, et al. Comparison of the effect of interleukin-6 and interleukin-1 on collagenase and proteoglycan production by chondrocytes. J Rheumatol 1990;17:953-7.
    • (1990) J Rheumatol , vol.17 , pp. 953-957
    • Kandel, R.A.1    Petelycky, M.2    Dinarello, C.A.3
  • 22
    • 0025359009 scopus 로고
    • Modulation by interleukin-1 and tumor necrosis factor α of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and undifferentiated articular chondrocytes
    • Lefevre V, Peeters-Joris C, Vaes G. Modulation by interleukin-1 and tumor necrosis factor α of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and undifferentiated articular chondrocytes. Biochim Biophys Acta 1990;1052:366-78.
    • (1990) Biochim Biophys Acta , vol.1052 , pp. 366-378
    • Lefevre, V.1    Peeters-Joris, C.2    Vaes, G.3
  • 23
    • 0020055626 scopus 로고
    • Roentgenograms in primary care patients with acute low back pain: A cost-effectiveness analysis
    • Liang M, Komaroff AL. Roentgenograms in primary care patients with acute low back pain: A cost-effectiveness analysis. Arch Intern Med 1982;142:1108-12.
    • (1982) Arch Intern Med , vol.142 , pp. 1108-1112
    • Liang, M.1    Komaroff, A.L.2
  • 24
    • 0019431837 scopus 로고
    • Experimental intervertebral disc degeneration: Morphologic and proteoglycan changes over time
    • Lipson SJ, Muir H. Experimental intervertebral disc degeneration: Morphologic and proteoglycan changes over time. Arthritis Rheum 1981;24:12-21.
    • (1981) Arthritis Rheum , vol.24 , pp. 12-21
    • Lipson, S.J.1    Muir, H.2
  • 25
    • 0026197762 scopus 로고
    • Identification of human intervertebral disc stromelysin and its involvement in matrix degradation
    • Liu J, Roughley PJ, Mort JS. Identification of human intervertebral disc stromelysin and its involvement in matrix degradation. J Orthop Res 1991;9:568-75.
    • (1991) J Orthop Res , vol.9 , pp. 568-575
    • Liu, J.1    Roughley, P.J.2    Mort, J.S.3
  • 26
    • 0025734094 scopus 로고
    • Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA)
    • Lotz M, Guerne PA. Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA). J Biol Chem 1991;266:2017-22.
    • (1991) J Biol Chem , vol.266 , pp. 2017-2022
    • Lotz, M.1    Guerne, P.A.2
  • 27
    • 0015920833 scopus 로고
    • Chemical irritation of nerve-root in disc prolapse
    • Marshall LL, Trethewie ER. Chemical irritation of nerve-root in disc prolapse. Lancet 1973;2:320.
    • (1973) Lancet , vol.2 , pp. 320
    • Marshall, L.L.1    Trethewie, E.R.2
  • 28
    • 0017589055 scopus 로고
    • Chemical radiculitis: A clinical physiological and immunological study
    • Marshall LL, Trethewie ER, Curtain CC. Chemical radiculitis: A clinical physiological and immunological study. Clin Orthop 1977;129:61-7.
    • (1977) Clin Orthop , vol.129 , pp. 61-67
    • Marshall, L.L.1    Trethewie, E.R.2    Curtain, C.C.3
  • 29
    • 0023226602 scopus 로고
    • The inflammatory effect of nucleus pulposus: A possible element in the pathogenesis of low back pain
    • McCarron RF, Wimpee MW, Hudkins PG, et al. The inflammatory effect of nucleus pulposus: A possible element in the pathogenesis of low back pain. Spine 1987;12:760-4.
    • (1987) Spine , vol.12 , pp. 760-764
    • McCarron, R.F.1    Wimpee, M.W.2    Hudkins, P.G.3
  • 30
    • 0028361631 scopus 로고
    • The role of nitric oxide in the development and maintenance of the hyperalgesia produced by intraplantar injection of carrageenan in the rat
    • Meiler ST, Cummings CP, Traub RJ, Gebhart GF. The role of nitric oxide in the development and maintenance of the hyperalgesia produced by intraplantar injection of carrageenan in the rat. Neuroscience 1994;60:367-74.
    • (1994) Neuroscience , vol.60 , pp. 367-374
    • Meiler, S.T.1    Cummings, C.P.2    Traub, R.J.3    Gebhart, G.F.4
  • 31
    • 0023130338 scopus 로고
    • Neutral proteinases of the human intervertebral disc
    • Melrose J, Ghosh P, Taylor TKF. Neutral proteinases of the human intervertebral disc. Biochim Biophys Acta 1987; 923:483-95.
    • (1987) Biochim Biophys Acta , vol.923 , pp. 483-495
    • Melrose, J.1    Ghosh, P.2    Taylor, T.K.F.3
  • 32
    • 0001082030 scopus 로고
    • Rupture of the intervertebral disc with involvement of the spinal canal
    • Mixter WJ, Barr JS. Rupture of the intervertebral disc with involvement of the spinal canal. N Engl J Med 1934;211: 210-5.
    • (1934) N Engl J Med , vol.211 , pp. 210-215
    • Mixter, W.J.1    Barr, J.S.2
  • 33
    • 0014634541 scopus 로고
    • Intradiscal measurements of pH in patients with lumbar rhizopathies
    • Nachemson A. Intradiscal measurements of pH in patients with lumbar rhizopathies. Acta Orthop Scand 1969;40:23-42.
    • (1969) Acta Orthop Scand , vol.40 , pp. 23-42
    • Nachemson, A.1
  • 34
    • 0025695743 scopus 로고
    • Interleukin-1 induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human cartilage
    • Nietfeld JJ, Wilbrink B, Helle M, et al. Interleukin-1 induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human cartilage. Arthritis Rheum 1990;33:1695-701.
    • (1990) Arthritis Rheum , vol.33 , pp. 1695-1701
    • Nietfeld, J.J.1    Wilbrink, B.2    Helle, M.3
  • 35
    • 0026492442 scopus 로고
    • Glucocorticoids do not affect the induction of a novel calcium-dependent nitric oxide synthase in rabbit chondrocytes
    • Palmer RMJ, Andrews T, Foxwell NA, Moncada S. Glucocorticoids do not affect the induction of a novel calcium-dependent nitric oxide synthase in rabbit chondrocytes. Biochem Biochys Res Commun 1992;188:209-15.
    • (1992) Biochem Biochys Res Commun , vol.188 , pp. 209-215
    • Palmer, R.M.J.1    Andrews, T.2    Foxwell, N.A.3    Moncada, S.4
  • 36
    • 0018416093 scopus 로고
    • Fissuring of the posterior anulus fibrosus in the lumbar spine
    • Park WM, McCall IW, O'Brien JP, et al. Fissuring of the posterior anulus fibrosus in the lumbar spine. Br J Radiol 1979;52:382-7.
    • (1979) Br J Radiol , vol.52 , pp. 382-387
    • Park, W.M.1    McCall, I.W.2    O'Brien, J.P.3
  • 37
    • 0007004275 scopus 로고
    • Effects of graded compression and nucleus pulposus on nerve tissue: An experimental study in rabbits
    • Rydevik B, Brown MD, Ehira T, et al. Effects of graded compression and nucleus pulposus on nerve tissue: An experimental study in rabbits. Acta Orthop Scand 1983;54:760-4.
    • (1983) Acta Orthop Scand , vol.54 , pp. 760-764
    • Rydevik, B.1    Brown, M.D.2    Ehira, T.3
  • 39
    • 0019941893 scopus 로고
    • Collagenolytic enzyme systems in human intervertebral disc: Their control, mechanism, and their possible role in the initiation of biomechanical failure
    • Sedowofia KA, Tomlinson IW, Weiss JB, Hilton RH, Jayson MIV. Collagenolytic enzyme systems in human intervertebral disc: Their control, mechanism, and their possible role in the initiation of biomechanical failure. Spine 1982;7:212-22.
    • (1982) Spine , vol.7 , pp. 212-222
    • Sedowofia, K.A.1    Tomlinson, I.W.2    Weiss, J.B.3    Hilton, R.H.4    Jayson, M.I.V.5
  • 40
    • 70449253829 scopus 로고
    • Sciatica and the intervertebral disc: An experimental study
    • Smyth MJ, Wright V. Sciatica and the intervertebral disc: An experimental study. J Bone Joint Surg [Am] 1958;40: 1401-18.
    • (1958) J Bone Joint Surg [Am] , vol.40 , pp. 1401-1418
    • Smyth, M.J.1    Wright, V.2
  • 41
    • 0027412607 scopus 로고
    • Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells
    • Stadler J, Harbrecht BG, DiSilvio M, et al. Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells. J Leukoc Biol 1993;53: 165-72.
    • (1993) J Leukoc Biol , vol.53 , pp. 165-172
    • Stadler, J.1    Harbrecht, B.G.2    DiSilvio, M.3
  • 42
    • 0025721956 scopus 로고
    • Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide
    • Stadler J, Stefanovic-Racic M, Billiar TR, et al. Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide. J Immunol 1991;147:3915-20.
    • (1991) J Immunol , vol.147 , pp. 3915-3920
    • Stadler, J.1    Stefanovic-Racic, M.2    Billiar, T.R.3
  • 46
    • 0344192915 scopus 로고
    • Synovial cytokines impair the function of the sciatic nerve in rats: A possible element in the pathophysiology of radicular syndromes
    • Wehling P, Bandara G, Evans CH, Schulitz KP. Synovial cytokines impair the function of the sciatic nerve in rats: A possible element in the pathophysiology of radicular syndromes. Orthop Trans 1990;14:338-9.
    • (1990) Orthop Trans , vol.14 , pp. 338-339
    • Wehling, P.1    Bandara, G.2    Evans, C.H.3    Schulitz, K.P.4
  • 47
    • 0021126634 scopus 로고
    • A study of computer-assisted tomography: I. The incidence of positive CAT scans in an asymptomatic group of patients
    • Wiesel SW, Tsourmas N, Feffer HL, et al. A study of computer-assisted tomography: I. The incidence of positive CAT scans in an asymptomatic group of patients. Spine 1984; 9:549-51.
    • (1984) Spine , vol.9 , pp. 549-551
    • Wiesel, S.W.1    Tsourmas, N.2    Feffer, H.L.3
  • 49
    • 0026111656 scopus 로고
    • Role of metalloproteinases in human osteoarthritis
    • Woessner JF, Gunja-Smith Z. Role of metalloproteinases in human osteoarthritis. J Rheumatol 1991;18(Suppl):99-101.
    • (1991) J Rheumatol , vol.18 , Issue.SUPPL. , pp. 99-101
    • Woessner, J.F.1    Gunja-Smith, Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.