메뉴 건너뛰기




Volumn 97, Issue 3, 2006, Pages 772-783

Spatial and temporal relationship between monocyte chemoattractant protein-1 expression and spinal glial activation following peripheral nerve injury

Author keywords

Chemokines; Neuro glial interaction; Neuropathic pain

Indexed keywords

MONOCYTE CHEMOTACTIC PROTEIN 1;

EID: 33645850108     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03746.x     Document Type: Article
Times cited : (305)

References (57)
  • 3
    • 0034960228 scopus 로고    scopus 로고
    • CXCR4-activated astrocyte glutamate release via TNFalpha: Amplification by microglia triggers neurotoxicity
    • Bezzi P. Domercq M. Brambilla L. et al. 2001 CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nat. Neurosci. 4 702 710.
    • (2001) Nat. Neurosci. , vol.4 , pp. 702-710
    • Bezzi, P.1    Domercq, M.2    Brambilla, L.3
  • 5
    • 0030859754 scopus 로고    scopus 로고
    • Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat
    • Colburn R. W. DeLeo J. A. Rickman A. J. Yeager M. P. Kwon P. Hickey W. F. 1997 Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat. J. Neuroimmunol. 79 163 175.
    • (1997) J. Neuroimmunol. , vol.79 , pp. 163-175
    • Colburn, R.W.1    Deleo, J.A.2    Rickman, A.J.3    Yeager, M.P.4    Kwon, P.5    Hickey, W.F.6
  • 6
    • 0032978701 scopus 로고    scopus 로고
    • The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior
    • Colburn R. W. Rickman A. J. DeLeo J. A. 1999 The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior. Exp. Neurol. 157 289 304.
    • (1999) Exp. Neurol. , vol.157 , pp. 289-304
    • Colburn, R.W.1    Rickman, A.J.2    Deleo, J.A.3
  • 8
    • 0018867072 scopus 로고
    • Efficient analysis of experimental observations
    • Dixon W. J. 1980 Efficient analysis of experimental observations. Annu. Rev. Pharmacol. Toxicol. 20 441 462.
    • (1980) Annu. Rev. Pharmacol. Toxicol. , vol.20 , pp. 441-462
    • Dixon, W.J.1
  • 10
    • 0033577464 scopus 로고    scopus 로고
    • Microglial reactions after subcutaneous formalin injection into the rat hind paw
    • Fu K. Y. Light A. R. Matsushima G. K. Maixner W. 1999 Microglial reactions after subcutaneous formalin injection into the rat hind paw. Brain Res. 825 59 67.
    • (1999) Brain Res. , vol.825 , pp. 59-67
    • Fu, K.Y.1    Light, A.R.2    Matsushima, G.K.3    Maixner, W.4
  • 12
    • 13144279282 scopus 로고    scopus 로고
    • Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
    • Harrison J. K. Jiang Y. Chen S. et al. 1998 Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc. Natl Acad. Sci. USA 95 10 896 10 901.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 10896-10901
    • Harrison, J.K.1    Jiang, Y.2    Chen, S.3
  • 13
    • 0034657820 scopus 로고    scopus 로고
    • Spinal glial activation and cytokine expression after lumbar root injury in the rat
    • Hashizume H. DeLeo J. A. Colburn R. W. Weinstein J. N. 2000 Spinal glial activation and cytokine expression after lumbar root injury in the rat. Spine 25 1206 1217.
    • (2000) Spine , vol.25 , pp. 1206-1217
    • Hashizume, H.1    Deleo, J.A.2    Colburn, R.W.3    Weinstein, J.N.4
  • 14
    • 0035911254 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis
    • Huang D. R. Wang J. Kivisakk P. Rollins B. J. Ransohoff R. M. 2001 Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. J. Exp. Med. 193 713 726.
    • (2001) J. Exp. Med. , vol.193 , pp. 713-726
    • Huang, D.R.1    Wang, J.2    Kivisakk, P.3    Rollins, B.J.4    Ransohoff, R.M.5
  • 15
    • 0034028817 scopus 로고    scopus 로고
    • Analysis of fractalkine receptor CX (3) CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
    • Jung S. Aliberti J. Graemmel P. Sunshine M. J. Kreutzberg G. W. Sher A. Littman D. R. 2000 Analysis of fractalkine receptor CX (3) CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell. Biol. 20 4106 4114.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4106-4114
    • Jung, S.1    Aliberti, J.2    Graemmel, P.3    Sunshine, M.J.4    Kreutzberg, G.W.5    Sher, A.6    Littman, D.R.7
  • 16
    • 0031737417 scopus 로고    scopus 로고
    • Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementia
    • Kelder W. McArthur J. C. Nance-Sproson T. McClernon D. Griffin D. E. 1998 Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementia. Ann. Neurol. 44 831 835.
    • (1998) Ann. Neurol. , vol.44 , pp. 831-835
    • Kelder, W.1    McArthur, J.C.2    Nance-Sproson, T.3    McClernon, D.4    Griffin, D.E.5
  • 17
    • 0036847840 scopus 로고    scopus 로고
    • Role of p38 and p44/42 mitogen-activated protein kinases in microglia
    • Koistinaho M. Koistinaho J. 2002 Role of p38 and p44/42 mitogen-activated protein kinases in microglia. Glia 40 175 183.
    • (2002) Glia , vol.40 , pp. 175-183
    • Koistinaho, M.1    Koistinaho, J.2
  • 18
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg G. W. 1996 Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19 312 318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 19
    • 0025790556 scopus 로고
    • Biological aspects of monocyte chemoattractant protein-1 (MCP-1)
    • Leonard E. J. Skeel A. Yoshimura T. 1991 Biological aspects of monocyte chemoattractant protein-1 (MCP-1). Adv. Exp. Med. Biol. 305 57 64.
    • (1991) Adv. Exp. Med. Biol. , vol.305 , pp. 57-64
    • Leonard, E.J.1    Skeel, A.2    Yoshimura, T.3
  • 20
    • 0037321869 scopus 로고    scopus 로고
    • Upregulation of FGF-2 in reactive spinal cord astrocytes following unilateral lumbar spinal nerve ligation
    • q29
    • Madiai F. Hussain S. R. Goettl V. M. Burry R. W. Stephens R. L. Jr. Hackshaw K. V. 2003 Upregulation of FGF-2 in reactive spinal cord astrocytes following unilateral lumbar spinal nerve ligation. Exp. Brain Res. 148 366 376. q29
    • (2003) Exp. Brain Res. , vol.148 , pp. 366-376
    • Madiai, F.1    Hussain, S.R.2    Goettl, V.M.3    Burry, R.W.4    Stephens Jr., R.L.5    Hackshaw, K.V.6
  • 21
    • 0041864076 scopus 로고    scopus 로고
    • Cytokine, chemokine and growth factor gene profiling of cultured human astrocytes after exposure to proinflammatory stimuli
    • Meeuwsen S. Persoon-Deen C. Bsibsi M. Ravid R. van Noort J. M. 2003 Cytokine, chemokine and growth factor gene profiling of cultured human astrocytes after exposure to proinflammatory stimuli. Glia 43 243 253.
    • (2003) Glia , vol.43 , pp. 243-253
    • Meeuwsen, S.1    Persoon-Deen, C.2    Bsibsi, M.3    Ravid, R.4    Van Noort, J.M.5
  • 22
    • 18244396919 scopus 로고    scopus 로고
    • Neuroscience. the dark side of glia
    • Miller G. 2005 Neuroscience. The dark side of glia. Science 308 778 781.
    • (2005) Science , vol.308 , pp. 778-781
    • Miller, G.1
  • 24
    • 0030032724 scopus 로고    scopus 로고
    • Fixed-diameter polyethylene cuffs applied to the rat sciatic nerve induce a painful neuropathy: Ultrastructural morphometric analysis of axonal alterations
    • Mosconi T. Kruger L. 1996 Fixed-diameter polyethylene cuffs applied to the rat sciatic nerve induce a painful neuropathy: ultrastructural morphometric analysis of axonal alterations. Pain 64 37 57.
    • (1996) Pain , vol.64 , pp. 37-57
    • Mosconi, T.1    Kruger, L.2
  • 25
    • 0032848244 scopus 로고    scopus 로고
    • Nerve constriction in the rat: Model of neuropathic, surgical and central pain
    • Pitcher G. M. Ritchie J. Henry J. L. 1999 Nerve constriction in the rat: model of neuropathic, surgical and central pain. Pain 83 37 46.
    • (1999) Pain , vol.83 , pp. 37-46
    • Pitcher, G.M.1    Ritchie, J.2    Henry, J.L.3
  • 26
    • 0037622717 scopus 로고    scopus 로고
    • Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy
    • Raghavendra V. Tanga F. DeLeo J. A. 2003 Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J. Pharmacol. Exp. Ther. 306 624 630.
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , pp. 624-630
    • Raghavendra, V.1    Tanga, F.2    Deleo, J.A.3
  • 28
    • 0028788849 scopus 로고
    • Ultrastructural features of the colocalization of calcitonin gene related peptide with substance P or somatostatin in the dorsal horn of the spinal cord
    • Ribeiro-da-Silva A. 1995 Ultrastructural features of the colocalization of calcitonin gene related peptide with substance P or somatostatin in the dorsal horn of the spinal cord. Can. J. Physiol. Pharmacol. 73 940 944.
    • (1995) Can. J. Physiol. Pharmacol. , vol.73 , pp. 940-944
    • Ribeiro-Da-Silva, A.1
  • 29
    • 0034660331 scopus 로고    scopus 로고
    • Extensive sprouting of sensory afferents and hyperalgesia induced by conditional expression of nerve growth factor in the adult spinal cord
    • Romero M. I. Rangappa N. Li L. Lightfoot E. Garry M. G. Smith G. M. 2000 Extensive sprouting of sensory afferents and hyperalgesia induced by conditional expression of nerve growth factor in the adult spinal cord. J. Neurosci. 20 4435 4445.
    • (2000) J. Neurosci. , vol.20 , pp. 4435-4445
    • Romero, M.I.1    Rangappa, N.2    Li, L.3    Lightfoot, E.4    Garry, M.G.5    Smith, G.M.6
  • 30
    • 9244256719 scopus 로고    scopus 로고
    • The effect of stimulated microglia conditioned media on BDNF gene expression of striatal astrocytes: Quantification by real-time PCR
    • Savli H. Gulkac M. D. Esen N. 2004 The effect of stimulated microglia conditioned media on BDNF gene expression of striatal astrocytes: quantification by real-time PCR. Int. J. Neurosci. 114 1601 1612.
    • (2004) Int. J. Neurosci. , vol.114 , pp. 1601-1612
    • Savli, H.1    Gulkac, M.D.2    Esen, N.3
  • 31
    • 0035809761 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein (MCP)-1 is rapidly expressed by sympathetic ganglion neurons following axonal injury
    • Schreiber R. C. Krivacic K. Kirby B. Vaccariello S. A. Wei T. Ransohoff R. M. Zigmond R. E. 2001 Monocyte chemoattractant protein (MCP)-1 is rapidly expressed by sympathetic ganglion neurons following axonal injury. Neuroreport 12 601 606.
    • (2001) Neuroreport , vol.12 , pp. 601-606
    • Schreiber, R.C.1    Krivacic, K.2    Kirby, B.3    Vaccariello, S.A.4    Wei, T.5    Ransohoff, R.M.6    Zigmond, R.E.7
  • 32
    • 6944234040 scopus 로고    scopus 로고
    • Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia
    • Simard A. R. Rivest S. 2004 Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia. FASEB J. 18 998 1000.
    • (2004) FASEB J. , vol.18 , pp. 998-1000
    • Simard, A.R.1    Rivest, S.2
  • 33
    • 0032729936 scopus 로고    scopus 로고
    • Efficacy of pharmacological treatments of neuropathic pain: An update and effect related to mechanism of drug action
    • Sindrup S. H. Jensen T. S. 1999 Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action. Pain 83 389 400.
    • (1999) Pain , vol.83 , pp. 389-400
    • Sindrup, S.H.1    Jensen, T.S.2
  • 34
    • 0347989376 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells
    • Song L. Pachter J. S. 2004 Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells. Microvasc. Res. 67 78 89.
    • (2004) Microvasc. Res. , vol.67 , pp. 78-89
    • Song, L.1    Pachter, J.S.2
  • 35
    • 0344465840 scopus 로고    scopus 로고
    • Potential role of MCP-1 in endothelial cell tight junction 'opening': Signaling via Rho and Rho kinase
    • Stamatovic S. M. Keep R. F. Kunkel S. L. Andjelkovic A. V. 2003 Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase. J. Cell Sci. 116 4615 4628.
    • (2003) J. Cell Sci. , vol.116 , pp. 4615-4628
    • Stamatovic, S.M.1    Keep, R.F.2    Kunkel, S.L.3    Andjelkovic, A.V.4
  • 36
    • 0035135939 scopus 로고    scopus 로고
    • Influence of injury and cytokines on synthesis of monocyte chemoattractant protein-1 mRNA in peripheral nervous tissue
    • Subang M. C. Richardson P. M. 2001 Influence of injury and cytokines on synthesis of monocyte chemoattractant protein-1 mRNA in peripheral nervous tissue. Eur. J. Neurosci. 13 521 528.
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 521-528
    • Subang, M.C.1    Richardson, P.M.2
  • 37
    • 0035857748 scopus 로고    scopus 로고
    • Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain
    • Sweitzer S. Martin D. DeLeo J. A. 2001a Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain. Neuroscience 103 529 539.
    • (2001) Neuroscience , vol.103 , pp. 529-539
    • Sweitzer, S.1    Martin, D.2    Deleo, J.A.3
  • 38
    • 0035018058 scopus 로고    scopus 로고
    • Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain
    • Sweitzer S. M. Schubert P. DeLeo J. A. 2001b Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain. J. Pharmacol. Exp. Ther. 297 1210 1217.
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , pp. 1210-1217
    • Sweitzer, S.M.1    Schubert, P.2    Deleo, J.A.3
  • 40
    • 1642404488 scopus 로고    scopus 로고
    • Enhanced production of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain: Possible involvement in the development of neuropathic pain
    • Tanaka T. Minami M. Nakagawa T. Satoh M. 2004 Enhanced production of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain: possible involvement in the development of neuropathic pain. Neurosci. Res. 48 463 469.
    • (2004) Neurosci. Res. , vol.48 , pp. 463-469
    • Tanaka, T.1    Minami, M.2    Nakagawa, T.3    Satoh, M.4
  • 41
    • 0347814979 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain
    • Tanga F. Y. Raghavendra V. DeLeo J. A. 2004 Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain. Neurochem. Int. 45 397 407.
    • (2004) Neurochem. Int. , vol.45 , pp. 397-407
    • Tanga, F.Y.1    Raghavendra, V.2    Deleo, J.A.3
  • 42
    • 0343517178 scopus 로고    scopus 로고
    • Increased expression of chemokines (MCP-1, MIP-1alpha, RANTES) after peripheral nerve transection
    • Taskinen H. S. Roytta M. 2000 Increased expression of chemokines (MCP-1, MIP-1alpha, RANTES) after peripheral nerve transection. J. Peripher. Nerv. Syst. 5 75 81.
    • (2000) J. Peripher. Nerv. Syst. , vol.5 , pp. 75-81
    • Taskinen, H.S.1    Roytta, M.2
  • 44
    • 0035844702 scopus 로고    scopus 로고
    • Regulation of the gene encoding the monocyte chemoattractant protein 1 (MCP-1) in the mouse and rat brain in response to circulating LPS and proinflammatory cytokines
    • Thibeault I. Laflamme N. Rivest S. 2001 Regulation of the gene encoding the monocyte chemoattractant protein 1 (MCP-1) in the mouse and rat brain in response to circulating LPS and proinflammatory cytokines. J. Comp. Neurol. 434 461 477.
    • (2001) J. Comp. Neurol. , vol.434 , pp. 461-477
    • Thibeault, I.1    Laflamme, N.2    Rivest, S.3
  • 45
    • 0032528168 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein 1 is responsible for macrophage recruitment following injury to sciatic nerve
    • Toews A. D. Barrett C. Morell P. 1998 Monocyte chemoattractant protein 1 is responsible for macrophage recruitment following injury to sciatic nerve. J. Neurosci. Res. 53 260 267.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 260-267
    • Toews, A.D.1    Barrett, C.2    Morell, P.3
  • 48
    • 13144276331 scopus 로고    scopus 로고
    • Neuropathic pain and spinal microglia: A big problem from molecules in 'small' glia
    • Tsuda M. Inoue K. Salter M. W. 2005 Neuropathic pain and spinal microglia: a big problem from molecules in 'small' glia. Trends Neurosci. 28 101 107.
    • (2005) Trends Neurosci. , vol.28 , pp. 101-107
    • Tsuda, M.1    Inoue, K.2    Salter, M.W.3
  • 49
    • 0033956898 scopus 로고    scopus 로고
    • Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury
    • Tsujino H. Kondo E. Fukuoka T. Dai Y. Tokunaga A. Miki K. Yonenobu K. Ochi T. Noguchi K. 2000 Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: a novel neuronal marker of nerve injury. Mol. Cell. Neurosci. 15 170 182.
    • (2000) Mol. Cell. Neurosci. , vol.15 , pp. 170-182
    • Tsujino, H.1    Kondo, E.2    Fukuoka, T.3    Dai, Y.4    Tokunaga, A.5    Miki, K.6    Yonenobu, K.7    Ochi, T.8    Noguchi, K.9
  • 50
    • 4544252839 scopus 로고    scopus 로고
    • Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions
    • Verge G. M. Milligan E. D. Maier S. F. Watkins L. R. Naeve G. S. Foster A. C. 2004 Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. Eur. J. Neurosci. 20 1150 1160.
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1150-1160
    • Verge, G.M.1    Milligan, E.D.2    Maier, S.F.3    Watkins, L.R.4    Naeve, G.S.5    Foster, A.C.6
  • 51
    • 0002766649 scopus 로고    scopus 로고
    • Inflammatory markers in chronic neurodegenerative disorders with emphasis on Alzheimer's disease
    • , in. Humana Press Inc.q31 , pp.
    • Walker D. G. 1998 Inflammatory markers in chronic neurodegenerative disorders with emphasis on Alzheimer's disease, in Neuroinflammation, Mechanism and Management Wood P. L., ed.), pp. 61 90. Humana Press Inc.q31
    • (1998) Neuroinflammation, Mechanism and Management*Wood P. L. , Ed.) , pp. 61-90
    • Walker, D.G.1
  • 52
    • 0035426434 scopus 로고    scopus 로고
    • Glial activation: A driving force for pathological pain
    • Watkins L. R. Milligan E. D. Maier S. F. 2001a Glial activation: a driving force for pathological pain. Trends Neurosci. 24 450 455.
    • (2001) Trends Neurosci. , vol.24 , pp. 450-455
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 53
    • 0034882399 scopus 로고    scopus 로고
    • Spinal cord glia: New players in pain
    • Watkins L. R. Milligan E. D. Maier S. F. 2001b Spinal cord glia: new players in pain. Pain 93 201 205.
    • (2001) Pain , vol.93 , pp. 201-205
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 54
    • 0038748399 scopus 로고    scopus 로고
    • Glial proinflammatory cytokines mediate exaggerated pain states: Implications for clinical pain
    • Watkins L. R. Milligan E. D. Maier S. F. 2003 Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain. Adv. Exp. Med. Biol. 521 1 21.
    • (2003) Adv. Exp. Med. Biol. , vol.521 , pp. 1-21
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 55
    • 0038684167 scopus 로고    scopus 로고
    • Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models
    • Zhang J. Hoffert C. Vu H. K. Groblewski T. Ahmad S. O'Donnell D. 2003 Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models. Eur. J. Neurosci. 17 2750 2754.
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 2750-2754
    • Zhang, J.1    Hoffert, C.2    Vu, H.K.3    Groblewski, T.4    Ahmad, S.5    O'Donnell, D.6
  • 56
    • 0032838324 scopus 로고    scopus 로고
    • Distribution, regulation and colocalization of the genes encoding the EP2- and EP4-PGE2 receptors in the rat brain and neuronal responses to systemic inflammation
    • Zhang J. Rivest S. 1999 Distribution, regulation and colocalization of the genes encoding the EP2- and EP4-PGE2 receptors in the rat brain and neuronal responses to systemic inflammation. Eur J. Neurosci. 11 2651 2668.
    • (1999) Eur J. Neurosci. , vol.11 , pp. 2651-2668
    • Zhang, J.1    Rivest, S.2
  • 57
    • 14044252008 scopus 로고    scopus 로고
    • ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model
    • Zhuang Z. Y. Gerner P. Woolf C. J. Ji R. R. 2005 ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model. Pain 114 149 159.
    • (2005) Pain , vol.114 , pp. 149-159
    • Zhuang, Z.Y.1    Gerner, P.2    Woolf, C.J.3    Ji, R.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.