메뉴 건너뛰기




Volumn 3, Issue 4, 2013, Pages 438-446

The role of T cell immunity in HIV-1 infection

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; HLA ANTIGEN CLASS 1; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

EID: 84885083909     PISSN: 18796257     EISSN: 18796265     Source Type: Journal    
DOI: 10.1016/j.coviro.2013.05.009     Document Type: Review
Times cited : (14)

References (98)
  • 7
    • 79952705605 scopus 로고    scopus 로고
    • Revisiting immune exhaustion during HIV infection
    • Khaitan A, Unutmaz D: Revisiting immune exhaustion during HIV infection. Curr HIV/AIDS Rep 2011, 8:4-11.
    • (2011) Curr HIV/AIDS Rep , vol.8 , pp. 4-11
    • Khaitan, A.1    Unutmaz, D.2
  • 10
    • 34548689151 scopus 로고    scopus 로고
    • Human Immunodeficiency Virus Controllers: Mechanisms of Durable Virus Control in the Absence of Antiretroviral Therapy
    • DOI 10.1016/j.immuni.2007.08.010, PII S1074761307004141
    • Deeks SG, Walker BD: Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 2007, 27:406-416. (Pubitemid 47418678)
    • (2007) Immunity , vol.27 , Issue.3 , pp. 406-416
    • Deeks, S.G.1    Walker, B.D.2
  • 12
    • 80052285180 scopus 로고    scopus 로고
    • Human leukocyte antigen variants B44 and B57 are consistently favorable during two distinct phases of primary HIV-1 infection in sub- Saharan Africans with several viral subtypes
    • Tang J, Cormier E, Gilmour J, Price MA, Prentice HA, Song W, Kamali A, Karita E, Lakhi S, Sanders EJ et al.: Human leukocyte antigen variants B44 and B57 are consistently favorable during two distinct phases of primary HIV-1 infection in sub- Saharan Africans with several viral subtypes. J Virol 2011, 85:8894-8902.
    • (2011) J Virol , vol.85 , pp. 8894-8902
    • Tang, J.1    Cormier, E.2    Gilmour, J.3    Price, M.A.4    Prentice, H.A.5    Song, W.6    Kamali, A.7    Karita, E.8    Lakhi, S.9    Sanders, E.J.10
  • 15
    • 78049495989 scopus 로고    scopus 로고
    • Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection
    • Brockman MA, Brumme ZL, Brumme CJ, Miura T, Sela J, Rosato PC, Kadie CM, Carlson JM, Markle TJ, Streeck H et al.: Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection. J Virol 2010, 84:11937-11949.
    • (2010) J Virol , vol.84 , pp. 11937-11949
    • Brockman, M.A.1    Brumme, Z.L.2    Brumme, C.J.3    Miura, T.4    Sela, J.5    Rosato, P.C.6    Kadie, C.M.7    Carlson, J.M.8    Markle, T.J.9    Streeck, H.10
  • 16
    • 77952742298 scopus 로고    scopus 로고
    • Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection
    • This article provided a framework for HLA-*B57-mediated control of HIV replication by defining how the peptide-binding characteristics of this molecule during thymic selection select for a larger repertoire of HLA- *B57 clones with broader specificity for HIV sequences that are more refractive for mutational escape by HIV
    • Kosmrlj A, Read EL, Qi Y, Allen TM, Altfeld M, Deeks SG, Pereyra F, Carrington M, Walker BD, Chakraborty AK: Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection. Nature 2010, 465:350-354. This article provided a framework for HLA-*B57-mediated control of HIV replication by defining how the peptide-binding characteristics of this molecule during thymic selection select for a larger repertoire of HLA- *B57 clones with broader specificity for HIV sequences that are more refractive for mutational escape by HIV.
    • (2010) Nature , vol.465 , pp. 350-354
    • Kosmrlj, A.1    Read, E.L.2    Qi, Y.3    Allen, T.M.4    Altfeld, M.5    Deeks, S.G.6    Pereyra, F.7    Carrington, M.8    Walker, B.D.9    Chakraborty, A.K.10
  • 19
    • 78650084232 scopus 로고    scopus 로고
    • The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
    • The authors demonstrated that a small number of amino acids that flank the binding grove in HLA molecules are the major genetic determinants for HIV control or susceptibility
    • Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M et al.: The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science 2010, 330:1551-1557. The authors demonstrated that a small number of amino acids that flank the binding grove in HLA molecules are the major genetic determinants for HIV control or susceptibility.
    • (2010) Science , vol.330 , pp. 1551-1557
    • Pereyra, F.1    Jia, X.2    McLaren, P.J.3    Telenti, A.4    De Bakker, P.I.5    Walker, B.D.6    Ripke, S.7    Brumme, C.J.8    Pulit, S.L.9    Carrington, M.10
  • 20
    • 0038581912 scopus 로고    scopus 로고
    • The Influence of HLA Genotype on AIDS
    • DOI 10.1146/annurev.med.54.101601.152346
    • Carrington M, O'Brien SJ: The influence of HLA genotype on AIDS. Annu Rev Med 2003, 54:535-551. (Pubitemid 37386411)
    • (2003) Annual Review of Medicine , vol.54 , pp. 535-551
    • Carrington, M.1    O'Brien, S.J.2
  • 23
    • 34347214119 scopus 로고    scopus 로고
    • Humoral immunity to HIV-1: Neutralization and beyond
    • DOI 10.1111/j.1365-2796.2007.01819.x
    • Huber M, Trkola A: Humoral immunity to HIV-1: neutralization and beyond. J Intern Med 2007, 262:5-25. (Pubitemid 47000630)
    • (2007) Journal of Internal Medicine , vol.262 , Issue.1 , pp. 5-25
    • Huber, M.1    Trkola, A.2
  • 24
    • 0028041344 scopus 로고
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • Borrow P, Lewicki H, Hahn BH, Shaw GM, Oldstone MB: Virusspecific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994, 68:6103-6110. (Pubitemid 24258634)
    • (1994) Journal of Virology , vol.68 , Issue.9 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, G.M.4    Oldstone, M.B.A.5
  • 25
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, Borkowsky W, Farthing C, Ho DD: Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 1994, 68:4650-4655. (Pubitemid 24183063)
    • (1994) Journal of Virology , vol.68 , Issue.7 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3    Andrews, C.A.4    McLeod, G.5    Borkowsky, W.6    Farthing, C.7    Ho, D.D.8
  • 35
    • 79953815120 scopus 로고    scopus 로고
    • Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression
    • This study reveals that HIV-specific CD8 T cells from elite controllers express higher levels of the transcription factor T-bet. A positive correlation was observed between T-bet expression and both perforin and Granzyme B expression levels
    • Hersperger AR, Martin JN, Shin LY, Sheth PM, Kovacs CM, Cosma GL, Makedonas G, Pereyra F, Walker BD, Kaul R et al.: Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression. Blood 2011, 117:3799-3808. This study reveals that HIV-specific CD8 T cells from elite controllers express higher levels of the transcription factor T-bet. A positive correlation was observed between T-bet expression and both perforin and Granzyme B expression levels.
    • (2011) Blood , vol.117 , pp. 3799-3808
    • Hersperger, A.R.1    Martin, J.N.2    Shin, L.Y.3    Sheth, P.M.4    Kovacs, C.M.5    Cosma, G.L.6    Makedonas, G.7    Pereyra, F.8    Walker, B.D.9    Kaul, R.10
  • 37
    • 77956793480 scopus 로고    scopus 로고
    • Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gagspecific responses dominate in rectal mucosa of HIV controllers
    • Ferre AL, Lemongello D, Hunt PW, Morris MM, Garcia JC, Pollard RB, Yee HFJ, Martin JN, Deeks SG, Shacklett BL: Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gagspecific responses dominate in rectal mucosa of HIV controllers. J Virol 2010, 84:10354-10365.
    • (2010) J Virol , vol.84 , pp. 10354-10365
    • Ferre, A.L.1    Lemongello, D.2    Hunt, P.W.3    Morris, M.M.4    Garcia, J.C.5    Pollard, R.B.6    Yee, H.F.J.7    Martin, J.N.8    Deeks, S.G.9    Shacklett, B.L.10
  • 38
    • 67650924875 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells
    • Streeck H, Jolin JS, Qi Y, Yassine-Diab B, Johnson RC, Kwon DS, Addo MM, Brumme C, Routy JP, Little S et al.: Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells. J Virol 2009, 83:7641-7648.
    • (2009) J Virol , vol.83 , pp. 7641-7648
    • Streeck, H.1    Jolin, J.S.2    Qi, Y.3    Yassine-Diab, B.4    Johnson, R.C.5    Kwon, D.S.6    Addo, M.M.7    Brumme, C.8    Routy, J.P.9    Little, S.10
  • 42
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • DOI 10.1038/nature04444, PII NATURE04444
    • Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, Freeman GJ, Ahmed R: Restoring function in exhausted CD8T cells during chronic viral infection. Nature 2006, 439:682-687. (Pubitemid 43237609)
    • (2006) Nature , vol.439 , Issue.7077 , pp. 682-687
    • Barber, D.L.1    Wherry, E.J.2    Masopust, D.3    Zhu, B.4    Allison, J.P.5    Sharpe, A.H.6    Freeman, G.J.7    Ahmed, R.8
  • 44
    • 77957781776 scopus 로고    scopus 로고
    • Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
    • Described the cellular mechanism by which the inhibitory marker PD-1 contributes to CD8 T cell exhaustion by transcriptional activation of the T cell inhibiting gene, BATF. BATF and related genes were therefore identified as potential new targets for therapy
    • Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, Eichbaum Q, Julg B, Jesneck JL, Brosnahan K, Imam S et al.: Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF. Nat Med 2010, 16:1147-1151. Described the cellular mechanism by which the inhibitory marker PD-1 contributes to CD8 T cell exhaustion by transcriptional activation of the T cell inhibiting gene, BATF. BATF and related genes were therefore identified as potential new targets for therapy.
    • (2010) Nat Med , vol.16 , pp. 1147-1151
    • Quigley, M.1    Pereyra, F.2    Nilsson, B.3    Porichis, F.4    Fonseca, C.5    Eichbaum, Q.6    Julg, B.7    Jesneck, J.L.8    Brosnahan, K.9    Imam, S.10
  • 46
    • 79955476141 scopus 로고    scopus 로고
    • HIV-specific CD4T cells and immune control of viral replication
    • Porichis F, Kaufmann DE: HIV-specific CD4T cells and immune control of viral replication. Curr Opin HIV AIDS 2011, 6:174-180.
    • (2011) Curr Opin HIV AIDS , vol.6 , pp. 174-180
    • Porichis, F.1    Kaufmann, D.E.2
  • 47
    • 78649516786 scopus 로고    scopus 로고
    • HIV-1- specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function
    • Chevalier MF, Julg B, Pyo A, Flanders M, Ranasinghe S, Soghoian DZ, Kwon DS, Rychert J, Lian J, Muller MI et al.: HIV-1- specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function. J Virol 2011, 85:733-741.
    • (2011) J Virol , vol.85 , pp. 733-741
    • Chevalier, M.F.1    Julg, B.2    Pyo, A.3    Flanders, M.4    Ranasinghe, S.5    Soghoian, D.Z.6    Kwon, D.S.7    Rychert, J.8    Lian, J.9    Muller, M.I.10
  • 48
    • 73949110184 scopus 로고    scopus 로고
    • Dynamics and consequences of IL-21 production in HIV-infected individuals: A longitudinal and cross-sectional study
    • Iannello A, Boulassel MR, Samarani S, Debbeche O, Tremblay C, Toma E, Routy JP, Ahmad A: Dynamics and consequences of IL-21 production in HIV-infected individuals: A longitudinal and cross-sectional study. J Immunol 2010, 184:114-126.
    • (2010) J Immunol , vol.184 , pp. 114-126
    • Iannello, A.1    Boulassel, M.R.2    Samarani, S.3    Debbeche, O.4    Tremblay, C.5    Toma, E.6    Routy, J.P.7    Ahmad, A.8
  • 51
    • 34548637484 scopus 로고    scopus 로고
    • Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction
    • D'Souza M, Fontenot AP, Mack DG, Lozupone C, Dillon S, Meditz A, Wilson CC, Connick E, Palmer BE: Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction. J Immunol 2007, 179:1979-1987.
    • (2007) J Immunol , vol.179 , pp. 1979-1987
    • D'souza, M.1    Fontenot, A.P.2    MacK, D.G.3    Lozupone, C.4    Dillon, S.5    Meditz, A.6    Wilson, C.C.7    Connick, E.8    Palmer, B.E.9
  • 53
    • 42649120075 scopus 로고    scopus 로고
    • Regulation and functions of Blimp-1 in T and B lymphocytes
    • DOI 10.1146/annurev.immunol.26.021607.090241
    • Martins G, Calame K: Regulation and functions of Blimp-1 in T and B lymphocytes. Annu Rev Immunol 2008, 26:133-169. (Pubitemid 351600373)
    • (2008) Annual Review of Immunology , vol.26 , pp. 133-169
    • Martins, G.1    Calame, K.2
  • 54
    • 84864754110 scopus 로고    scopus 로고
    • MiR-9 enhances IL-2 production in activated human CD4(+) T cells by repressing Blimp-1
    • Thiele S, Wittmann J, Jack HM, Pahl A: miR-9 enhances IL-2 production in activated human CD4(+) T cells by repressing Blimp-1. Eur J Immunol 2012, 42:2100-2108.
    • (2012) Eur J Immunol , vol.42 , pp. 2100-2108
    • Thiele, S.1    Wittmann, J.2    Jack, H.M.3    Pahl, A.4
  • 56
    • 84873712646 scopus 로고    scopus 로고
    • Control of HIV infection: Escape from the shadow of Blimp-1
    • Thaventhiran JE, Fearon DT: Control of HIV infection: escape from the shadow of Blimp-1. Eur J Immunol 2013, 43:323-326.
    • (2013) Eur J Immunol , vol.43 , pp. 323-326
    • Thaventhiran, J.E.1    Fearon, D.T.2
  • 60
    • 84872093577 scopus 로고    scopus 로고
    • The split personality of regulatory T cells in HIV infection
    • Chevalier MF, Weiss L: The split personality of regulatory T cells in HIV infection. Blood 2013, 121:29-37.
    • (2013) Blood , vol.121 , pp. 29-37
    • Chevalier, M.F.1    Weiss, L.2
  • 62
    • 77951072478 scopus 로고    scopus 로고
    • Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollers
    • Loke P, Favre D, Hunt PW, Leung JM, Kanwar B, Martin JN, Deeks SG, McCune JM: Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollers. Blood 2010, 115:e20-e32.
    • (2010) Blood , vol.115
    • Loke, P.1    Favre, D.2    Hunt, P.W.3    Leung, J.M.4    Kanwar, B.5    Martin, J.N.6    Deeks, S.G.7    McCune, J.M.8
  • 63
    • 78651396992 scopus 로고    scopus 로고
    • Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease
    • Schulze Zur Wiesch J, Thomssen A, Hartjen P, Toth I, Lehmann C, Meyer-Olson D, Colberg K, Frerk S, Babikir D, Schmiedel S et al.: Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease. J Virol 2011, 85:1287-1297.
    • (2011) J Virol , vol.85 , pp. 1287-1297
    • Schulze, Z.W.J.1    Thomssen, A.2    Hartjen, P.3    Toth, I.4    Lehmann, C.5    Meyer-Olson, D.6    Colberg, K.7    Frerk, S.8    Babikir, D.9    Schmiedel, S.10
  • 64
    • 82655183583 scopus 로고    scopus 로고
    • Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy
    • Presicce P, Orsborn K, King E, Pratt J, Fichtenbaum CJ, Chougnet CA: Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy. PLoS ONE 2011, 6:e28118.
    • (2011) PLoS ONE , vol.6
    • Presicce, P.1    Orsborn, K.2    King, E.3    Pratt, J.4    Fichtenbaum, C.J.5    Chougnet, C.A.6
  • 67
    • 41649101126 scopus 로고    scopus 로고
    • Regulatory T cells in HIV infection: Who's suppressing what?
    • DOI 10.1007/s11904-008-0004-6
    • Seddiki N, Kelleher AD: Regulatory T cells in HIV infection: who's suppressing what? Curr HIV/AIDS Rep 2008, 5:20-26. (Pubitemid 351480777)
    • (2008) Current HIV/AIDS Reports , vol.5 , Issue.1 , pp. 20-26
    • Seddiki, N.1    Kelleher, A.D.2
  • 68
    • 84867741486 scopus 로고    scopus 로고
    • Identification of HIV-1-specific regulatory T-cells using HLA class II tetramers
    • Angin M, King M, Altfeld M, Walker BD, Wucherpfennig KW, Addo MM: Identification of HIV-1-specific regulatory T-cells using HLA class II tetramers. AIDS 2012, 26:2112-2115.
    • (2012) AIDS , vol.26 , pp. 2112-2115
    • Angin, M.1    King, M.2    Altfeld, M.3    Walker, B.D.4    Wucherpfennig, K.W.5    Addo, M.M.6
  • 72
    • 79956339815 scopus 로고    scopus 로고
    • Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanism
    • Moreno-Fernandez ME, Rueda CM, Rusie LK, Chougnet CA: Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanism. Blood 2011, 117:5372-5380.
    • (2011) Blood , vol.117 , pp. 5372-5380
    • Moreno-Fernandez, M.E.1    Rueda, C.M.2    Rusie, L.K.3    Chougnet, C.A.4
  • 73
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4T cells (TFH)
    • Crotty S: Follicular helper CD4T cells (TFH). Annu Rev Immunol 2011, 29:621-663.
    • (2011) Annu Rev Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 74
    • 70350492504 scopus 로고    scopus 로고
    • New insights into the differentiation and function of T follicular helper cells
    • King C: New insights into the differentiation and function of T follicular helper cells. Nat Rev Immunol 2009, 9:757-766.
    • (2009) Nat Rev Immunol , vol.9 , pp. 757-766
    • King, C.1
  • 75
    • 84859415408 scopus 로고    scopus 로고
    • Spatial alterations between CD4(+) T follicular helper, B, and CD8(+) T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape
    • Hong JJ, Amancha PK, Rogers K, Ansari AA, Villinger F: Spatial alterations between CD4(+) T follicular helper, B, and CD8(+) T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape. J Immunol 2012, 188:3247-3256.
    • (2012) J Immunol , vol.188 , pp. 3247-3256
    • Hong, J.J.1    Amancha, P.K.2    Rogers, K.3    Ansari, A.A.4    Villinger, F.5
  • 78
    • 84875539507 scopus 로고    scopus 로고
    • Simian immunodeficiency virus infects follicular helper CD4T cells in lymphoid tissues during pathogenic infection of pigtail macaques
    • Xu Y, Weatherall C, Bailey M, Alcantara S, De Rose R, Estaquier J, Wilson K, Suzuki K, Corbeil J, Cooper DA et al.: Simian immunodeficiency virus infects follicular helper CD4T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol 2013, 87:3760-3773.
    • (2013) J Virol , vol.87 , pp. 3760-3773
    • Xu, Y.1    Weatherall, C.2    Bailey, M.3    Alcantara, S.4    De Rose, R.5    Estaquier, J.6    Wilson, K.7    Suzuki, K.8    Corbeil, J.9    Cooper, D.A.10
  • 79
    • 0034606348 scopus 로고    scopus 로고
    • CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
    • Schaerli P, Willimann K, Lang AB, Lipp M, Loetscher P, Moser B: CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. J Exp Med 2000, 192:1553-1562.
    • (2000) J Exp Med , vol.192 , pp. 1553-1562
    • Schaerli, P.1    Willimann, K.2    Lang, A.B.3    Lipp, M.4    Loetscher, P.5    Moser, B.6
  • 81
    • 84869814713 scopus 로고    scopus 로고
    • Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguishprogressive and nonprogressive lentiviral infections
    • Brenchley JM, Vinton C, Tabb B, Hao XP, Connick E, Paiardini M, Lifson JD, Silvestri G, Estes JD: Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguishprogressive and nonprogressive lentiviral infections. Blood 2012, 120:4172-4181.
    • (2012) Blood , vol.120 , pp. 4172-4181
    • Brenchley, J.M.1    Vinton, C.2    Tabb, B.3    Hao, X.P.4    Connick, E.5    Paiardini, M.6    Lifson, J.D.7    Silvestri, G.8    Estes, J.D.9
  • 84
    • 74849138095 scopus 로고    scopus 로고
    • Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
    • Simpson N, Gatenby PA, Wilson A, Malik S, Fulcher DA, Tangye SG, Manku H, Vyse TJ, Roncador G, Huttley GA et al.: Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum 2010, 62:234-244.
    • (2010) Arthritis Rheum , vol.62 , pp. 234-244
    • Simpson, N.1    Gatenby, P.A.2    Wilson, A.3    Malik, S.4    Fulcher, D.A.5    Tangye, S.G.6    Manku, H.7    Vyse, T.J.8    Roncador, G.9    Huttley, G.A.10
  • 85
    • 84864555009 scopus 로고    scopus 로고
    • Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccine
    • Pallikkuth S, Parmigiani A, Silva SY, George VK, Fischl M, Pahwa R, Pahwa S: Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccine. Blood 2012, 120:985-993.
    • (2012) Blood , vol.120 , pp. 985-993
    • Pallikkuth, S.1    Parmigiani, A.2    Silva, S.Y.3    George, V.K.4    Fischl, M.5    Pahwa, R.6    Pahwa, S.7
  • 87
    • 45749101727 scopus 로고    scopus 로고
    • H17 cells
    • DOI 10.1038/nature07036, PII NATURE07036
    • Bettelli E, Korn T, Oukka M, Kuchroo VK: Induction and effector functions of T(H)17 cells. Nature 2008, 453:1051-1057. (Pubitemid 351871737)
    • (2008) Nature , vol.453 , Issue.7198 , pp. 1051-1057
    • Bettelli, E.1    Korn, T.2    Oukka, M.3    Kuchroo, V.K.4
  • 93
    • 84861720745 scopus 로고    scopus 로고
    • SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment
    • Hartigan-O'Connor DJ, Abel K, Van Rompay KK, Kanwar B, McCune JM: SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment. Sci Transl Med 2012, 4:136ra69.
    • (2012) Sci Transl Med , vol.4
    • Hartigan-O'Connor, D.J.1    Abel, K.2    Van Rompay, K.K.3    Kanwar, B.4    McCune, J.M.5
  • 94
    • 79957940672 scopus 로고    scopus 로고
    • Low level of regulatory T cells and maintenance of balance between regulatory T cells and TH17 cells in HIV-1-infected elite controllers
    • Brandt L, Benfield T, Mens H, Clausen LN, Katzenstein TL, Fomsgaard A, Karlsson I: Low level of regulatory T cells and maintenance of balance between regulatory T cells and TH17 cells in HIV-1-infected elite controllers. J Acquir Immune Defic Syndr 2011, 57:101-108.
    • (2011) J Acquir Immune Defic Syndr , vol.57 , pp. 101-108
    • Brandt, L.1    Benfield, T.2    Mens, H.3    Clausen, L.N.4    Katzenstein, T.L.5    Fomsgaard, A.6    Karlsson, I.7
  • 95
    • 79952445068 scopus 로고    scopus 로고
    • Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial
    • The authors of this study analysed HIV-1 sequences from newly infected volunteers in the STEP vaccine trial to determine if a 'sieve effect' occurred following vaccination with the MRKAd5 vaccine. The data presented revealed evidence of selective pressure from T cell responses on HIV-1 infection induced by the vaccine
    • Rolland M, Tovanabutra S, deCamp AC, Frahm N, Gilbert PB, Sanders-Buell E, Heath L, Magaret CA, Bose M, Bradfield A et al.: Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial. Nat Med 2011, 17:366-371. The authors of this study analysed HIV-1 sequences from newly infected volunteers in the STEP vaccine trial to determine if a 'sieve effect' occurred following vaccination with the MRKAd5 vaccine. The data presented revealed evidence of selective pressure from T cell responses on HIV-1 infection induced by the vaccine.
    • (2011) Nat Med , vol.17 , pp. 366-371
    • Rolland, M.1    Tovanabutra, S.2    Decamp, A.C.3    Frahm, N.4    Gilbert, P.B.5    Sanders-Buell, E.6    Heath, L.7    Magaret, C.A.8    Bose, M.9    Bradfield, A.10
  • 97
    • 84862904805 scopus 로고    scopus 로고
    • Extended follow-up confirms early vaccine-enhanced risk of HIV acquisition and demonstrates waning effect over time among participants in a randomized trial of recombinant adenovirus HIV vaccine (step study)
    • Duerr A, Huang Y, Buchbinder S, Coombs RW, Sanchez J, del Rio C, Casapia M, Santiago S, Gilbert P, Corey L, Robertson MN: Extended follow-up confirms early vaccine-enhanced risk of HIV acquisition and demonstrates waning effect over time among participants in a randomized trial of recombinant adenovirus HIV vaccine (step study). J Infect Dis 2012, 206:258-266.
    • (2012) J Infect Dis , vol.206 , pp. 258-266
    • Duerr, A.1    Huang, Y.2    Buchbinder, S.3    Coombs, R.W.4    Sanchez, J.5    Del, R.C.6    Casapia, M.7    Santiago, S.8    Gilbert, P.9    Corey, L.10    Robertson, M.N.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.