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Volumn 86, Issue 19, 2012, Pages 10505-10516

Early HLA-B*57-restricted CD8+T lymphocyte responses predict HIV-1 disease progression

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAG PROTEIN; HLA B57 ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; NEF PROTEIN; POL PROTEIN; REV PROTEIN; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; VIF PROTEIN; VIRUS ENVELOPE PROTEIN; VPR PROTEIN; VPU PROTEIN;

EID: 84868675469     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00102-12     Document Type: Article
Times cited : (33)

References (87)
  • 1
    • 0037302428 scopus 로고    scopus 로고
    • Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load
    • Addo MM, et al. 2003. Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. J. Virol. 77:2081-2092.
    • (2003) J. Virol. , vol.77 , pp. 2081-2092
    • Addo, M.M.1
  • 2
    • 27144513224 scopus 로고    scopus 로고
    • + T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution
    • + T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution. J. Virol. 79:13239-13249.
    • (2005) J. Virol. , vol.79 , pp. 13239-13249
    • Allen, T.M.1
  • 3
    • 12144287434 scopus 로고    scopus 로고
    • Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection
    • Altfeld M, et al. 2003. Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection. AIDS 17:2581-2591.
    • (2003) AIDS , vol.17 , pp. 2581-2591
    • Altfeld, M.1
  • 4
    • 33750869972 scopus 로고    scopus 로고
    • HLA alleles associated with delayed progression to AIDS contribute strongly to the initial CD8(+) T cell response against HIV-1
    • doi:10.1371/journal.pmed.0030403
    • Altfeld M, et al. 2006. HLA alleles associated with delayed progression to AIDS contribute strongly to the initial CD8(+) T cell response against HIV-1. PLoS Med. 3:e403. doi:10.1371/journal.pmed.0030403.
    • (2006) PLoS Med. , vol.3
    • Altfeld, M.1
  • 5
    • 33646701649 scopus 로고    scopus 로고
    • Maintenance of viral suppression in HIV-1-infected HLA-B*57Universal-GreekwithMathPi.-1.H11001 elite suppressors despite CTL escape mutations
    • Bailey JR, Williams TM, Siliciano RF, Blankson JN. 2006. Maintenance of viral suppression in HIV-1-infected HLA-B*57Universal-GreekwithMathPi.-1.H11001 elite suppressors despite CTL escape mutations. J. Exp. Med. 203:1357-1369.
    • (2006) J. Exp. Med. , vol.203 , pp. 1357-1369
    • Bailey, J.R.1    Williams, T.M.2    Siliciano, R.F.3    Blankson, J.N.4
  • 6
    • 78650664088 scopus 로고    scopus 로고
    • Rapid T cell receptor delineation reveals clonal expansion limitation of the magnitude of the HIV-1specific CD8+ T cell response
    • Balamurugan A, Ng HL, Yang OO. 2010. Rapid T cell receptor delineation reveals clonal expansion limitation of the magnitude of the HIV-1specific CD8+ T cell response. J. Immunol. 185:5935-5942.
    • (2010) J. Immunol. , vol.185 , pp. 5935-5942
    • Balamurugan, A.1    Ng, H.L.2    Yang, O.O.3
  • 7
    • 20144374940 scopus 로고    scopus 로고
    • CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides
    • Bansal A, et al. 2005. CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides. AIDS 19:241-250.
    • (2005) AIDS , vol.19 , pp. 241-250
    • Bansal, A.1
  • 8
    • 33646686040 scopus 로고    scopus 로고
    • HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
    • Betts MR, et al. 2006. HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood 107:4781-4789.
    • (2006) Blood , vol.107 , pp. 4781-4789
    • Betts, M.R.1
  • 9
    • 0028041344 scopus 로고
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J. Virol. 68:6103-6110.
    • (1994) J. Virol. , vol.68 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, G.M.4    Oldstone, M.B.5
  • 10
    • 62749167015 scopus 로고    scopus 로고
    • Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein
    • Boutwell CL, Rowley CF, Essex M. 2009. Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein. J. Virol. 83:2460-2468.
    • (2009) J. Virol. , vol.83 , pp. 2460-2468
    • Boutwell, C.L.1    Rowley, C.F.2    Essex, M.3
  • 11
    • 78049495989 scopus 로고    scopus 로고
    • Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection
    • Brockman MA, et al. 2010. Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection. J. Virol. 84:11937-11949.
    • (2010) J. Virol. , vol.84 , pp. 11937-11949
    • Brockman, M.A.1
  • 12
    • 50949117244 scopus 로고    scopus 로고
    • Marked epitopeand allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection
    • Brumme ZL, et al. 2008. Marked epitopeand allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection. J. Virol. 82:9216-9227.
    • (2008) J. Virol. , vol.82 , pp. 9216-9227
    • Brumme, Z.L.1
  • 14
    • 0034846053 scopus 로고    scopus 로고
    • Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations
    • Cao K, et al. 2001. Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations. Hum. Immunol. 62:1009-1030.
    • (2001) Hum. Immunol. , vol.62 , pp. 1009-1030
    • Cao, K.1
  • 15
    • 79953305839 scopus 로고    scopus 로고
    • CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21
    • Chen H, et al. 2011. CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21. J. Clin. Invest. 121:1549-1560.
    • (2011) J. Clin. Invest. , vol.121 , pp. 1549-1560
    • Chen, H.1
  • 16
    • 63149194225 scopus 로고    scopus 로고
    • Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes
    • Chen H, et al. 2009. Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes. J. Virol. 83:3138-3149.
    • (2009) J. Virol. , vol.83 , pp. 3138-3149
    • Chen, H.1
  • 17
    • 85047684409 scopus 로고    scopus 로고
    • Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients
    • Crawford H, et al. 2009. Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients. J. Exp. Med. 206:909-921.
    • (2009) J. Exp. Med. , vol.206 , pp. 909-921
    • Crawford, H.1
  • 18
    • 34548689151 scopus 로고    scopus 로고
    • Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy
    • Deeks SG, Walker BD. 2007. Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 27:406-416.
    • (2007) Immunity , vol.27 , pp. 406-416
    • Deeks, S.G.1    Walker, B.D.2
  • 19
    • 84858157707 scopus 로고    scopus 로고
    • The Multicenter AIDS Cohort Study, 1983 to...
    • Detels R, et al. 2012. The Multicenter AIDS Cohort Study, 1983 to... Public Health 126:196-198.
    • (2012) Public Health , vol.126 , pp. 196-198
    • Detels, R.1
  • 20
    • 85008071012 scopus 로고
    • Recent scientific contributions to understanding HIV/AIDS from the Multicenter AIDS Cohort Study
    • Detels R, et al. 1992. Recent scientific contributions to understanding HIV/AIDS from the Multicenter AIDS Cohort Study. J. Epidemiol. 2:S11-S19.
    • (1992) J. Epidemiol. , vol.2
    • Detels, R.1
  • 21
    • 77950877551 scopus 로고    scopus 로고
    • + T-cell responses better define HIV disease progression than HLA genotype
    • + T-cell responses better define HIV disease progression than HLA genotype. J. Virol. 84:4461-4468.
    • (2010) J. Virol. , vol.84 , pp. 4461-4468
    • Dinges, W.L.1
  • 22
    • 0029099764 scopus 로고
    • The Multicenter AIDS Cohort Study: retention after 9 1/2 years
    • Dudley J, et al. 1995. The Multicenter AIDS Cohort Study: retention after 9 1/2 years. Am. J. Epidemiol. 142:323-330.
    • (1995) Am. J. Epidemiol. , vol.142 , pp. 323-330
    • Dudley, J.1
  • 23
    • 0036171258 scopus 로고    scopus 로고
    • + T-cell responses to the Gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma
    • + T-cell responses to the Gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma. J. Virol. 76:2298-2305.
    • (2002) J. Virol. , vol.76 , pp. 2298-2305
    • Edwards, B.H.1
  • 24
    • 79961160736 scopus 로고    scopus 로고
    • + T cells evade Treg cell suppression
    • + T cells evade Treg cell suppression. Nat. Med. 17:989-995.
    • (2011) Nat. Med. , vol.17 , pp. 989-995
    • Elahi, S.1
  • 25
    • 43949124825 scopus 로고    scopus 로고
    • HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control
    • Emu B, et al. 2008. HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J. Virol. 82:5398-5407.
    • (2008) J. Virol. , vol.82 , pp. 5398-5407
    • Emu, B.1
  • 26
    • 34548134145 scopus 로고    scopus 로고
    • A whole-genome association study of major determinants for host control of HIV-1
    • Fellay J, et al. 2007. A whole-genome association study of major determinants for host control of HIV-1. Science 317:944-947.
    • (2007) Science , vol.317 , pp. 944-947
    • Fellay, J.1
  • 27
    • 31344458949 scopus 로고    scopus 로고
    • Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes
    • Frahm N, et al. 2006. Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes. Nat. Immunol. 7:173-178.
    • (2006) Nat. Immunol. , vol.7 , pp. 173-178
    • Frahm, N.1
  • 28
    • 34548794906 scopus 로고    scopus 로고
    • Extensive HLA class I allele promiscuity among viral CTL epitopes
    • Frahm N, et al. 2007. Extensive HLA class I allele promiscuity among viral CTL epitopes. Eur. J. Immunol. 37:2419-2433.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 2419-2433
    • Frahm, N.1
  • 29
    • 28644451011 scopus 로고    scopus 로고
    • AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis
    • Gao X, et al. 2005. AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis. Nat. Med. 11:1290-1292.
    • (2005) Nat. Med. , vol.11 , pp. 1290-1292
    • Gao, X.1
  • 30
    • 43549109265 scopus 로고    scopus 로고
    • Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients
    • Goepfert PA, et al. 2008. Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients. J. Exp. Med. 205:1009-1017.
    • (2008) J. Exp. Med. , vol.205 , pp. 1009-1017
    • Goepfert, P.A.1
  • 31
    • 67449147145 scopus 로고    scopus 로고
    • The first T cell response to transmitted/ founder virus contributes to the control of acute viremia in HIV-1 infection
    • Goonetilleke N, et al. 2009. The first T cell response to transmitted/ founder virus contributes to the control of acute viremia in HIV-1 infection. J. Exp. Med. 206:1253-1272.
    • (2009) J. Exp. Med. , vol.206 , pp. 1253-1272
    • Goonetilleke, N.1
  • 32
    • 0035862326 scopus 로고    scopus 로고
    • Substantial differences in specificity of HIVspecific cytotoxic T cells in acute and chronic HIV infection
    • Goulder PJ, et al. 2001. Substantial differences in specificity of HIVspecific cytotoxic T cells in acute and chronic HIV infection. J. Exp. Med. 193:181-194.
    • (2001) J. Exp. Med. , vol.193 , pp. 181-194
    • Goulder, P.J.1
  • 33
    • 0030459646 scopus 로고    scopus 로고
    • Novel, cross-restricted, conserved, and immunodominant cytotoxic T lymphocyte epitopes in slow progressors in HIV type 1 infection
    • Goulder PJ, et al. 1996. Novel, cross-restricted, conserved, and immunodominant cytotoxic T lymphocyte epitopes in slow progressors in HIV type 1 infection. AIDS Res. Hum. Retroviruses 12:1691-1698.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 1691-1698
    • Goulder, P.J.1
  • 34
    • 33750822983 scopus 로고    scopus 로고
    • Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection
    • Horton H, et al. 2006. Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection. J. Immunol. 177:7406-7415.
    • (2006) J. Immunol. , vol.177 , pp. 7406-7415
    • Horton, H.1
  • 35
    • 20144363311 scopus 로고    scopus 로고
    • + T-lymphocyte responses in blood and mucosa during chronic infection
    • + T-lymphocyte responses in blood and mucosa during chronic infection. J. Virol. 79:4289-4297.
    • (2005) J. Virol. , vol.79 , pp. 4289-4297
    • Ibarrondo, F.J.1
  • 36
    • 10744222966 scopus 로고    scopus 로고
    • Epitope escape mutation and decay of human immunodeficiency virus type 1-specific CTL responses
    • Jamieson BD, et al. 2003. Epitope escape mutation and decay of human immunodeficiency virus type 1-specific CTL responses. J. Immunol. 171: 5372-5379.
    • (2003) J. Immunol. , vol.171 , pp. 5372-5379
    • Jamieson, B.D.1
  • 37
    • 0037374385 scopus 로고    scopus 로고
    • Evaluation of antigen-specific responses using in vitro enriched T cells
    • Jones N, et al. 2003. Evaluation of antigen-specific responses using in vitro enriched T cells. J. Immunol. Methods 274:139-147.
    • (2003) J. Immunol. Methods , vol.274 , pp. 139-147
    • Jones, N.1
  • 38
    • 0006582115 scopus 로고    scopus 로고
    • Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection
    • Kaslow RA, et al. 1996. Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection. Nat. Med. 2:405-411.
    • (1996) Nat. Med. , vol.2 , pp. 405-411
    • Kaslow, R.A.1
  • 39
    • 0023186650 scopus 로고
    • The Multicenter AIDS Cohort Study: rationale, organization, and selected characteristics of the participants
    • Kaslow RA, et al. 1987. The Multicenter AIDS Cohort Study: rationale, organization, and selected characteristics of the participants. Am. J. Epidemiol. 126:310-318.
    • (1987) Am. J. Epidemiol. , vol.126 , pp. 310-318
    • Kaslow, R.A.1
  • 40
    • 33846101731 scopus 로고    scopus 로고
    • + T-cell responses to different HIV proteins have discordant associations with viral load
    • + T-cell responses to different HIV proteins have discordant associations with viral load. Nat. Med. 13:46-53.
    • (2007) Nat. Med. , vol.13 , pp. 46-53
    • Kiepiela, P.1
  • 41
    • 79251547401 scopus 로고    scopus 로고
    • Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes
    • doi:10.1053/j.gastro.2010.09.042
    • Kim AY, et al. 2011. Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes. Gastroenterology 140:686-696.e1. doi:10.1053/j.gastro.2010.09.042.
    • (2011) Gastroenterology , vol.140
    • Kim, A.Y.1
  • 42
    • 0028046638 scopus 로고
    • Genetic differences between bloodand brainderived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences
    • Korber BT, et al. 1994. Genetic differences between bloodand brainderived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences. J. Virol. 68:7467-7481.
    • (1994) J. Virol. , vol.68 , pp. 7467-7481
    • Korber, B.T.1
  • 43
    • 77952742298 scopus 로고    scopus 로고
    • Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection
    • Košmrlj A, et al. 2010. Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection. Nature 465:350-354.
    • (2010) Nature , vol.465 , pp. 350-354
    • Košmrlj, A.1
  • 44
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, et al. 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68:4650-4655.
    • (1994) J. Virol. , vol.68 , pp. 4650-4655
    • Koup, R.A.1
  • 45
    • 25444471257 scopus 로고    scopus 로고
    • HIV controllers: a homogeneous group of HIV1-infected patients with spontaneous control of viral replication
    • Lambotte O, et al. 2005. HIV controllers: a homogeneous group of HIV1-infected patients with spontaneous control of viral replication. Clin. Infect. Dis. 41:1053-1056.
    • (2005) Clin. Infect. Dis. , vol.41 , pp. 1053-1056
    • Lambotte, O.1
  • 46
    • 84868940161 scopus 로고    scopus 로고
    • Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics
    • doi:10.1371/journal.ppat.1000377
    • Lassen KG, et al. 2009. Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics. PLoS Pathog. 5:e1000377. doi:10.1371/journal.ppat.1000377.
    • (2009) PLoS Pathog. , vol.5
    • Lassen, K.G.1
  • 47
    • 34247109635 scopus 로고    scopus 로고
    • + T cells after early HIV-1 infection
    • + T cells after early HIV-1 infection. J. Virol. 81:4199-4214.
    • (2007) J. Virol. , vol.81 , pp. 4199-4214
    • Lichterfeld, M.1
  • 48
    • 71949099413 scopus 로고    scopus 로고
    • Conserved HIV-1 epitopes continuously elicit subdominant cytotoxic T-lymphocyte responses
    • Liu Y, et al. 2009. Conserved HIV-1 epitopes continuously elicit subdominant cytotoxic T-lymphocyte responses. J. Infect. Dis. 200:1825-1833.
    • (2009) J. Infect. Dis. , vol.200 , pp. 1825-1833
    • Liu, Y.1
  • 51
    • 33645240933 scopus 로고    scopus 로고
    • Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1
    • Martinez-Picado J, et al. 2006. Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J. Virol. 80:3617-3623.
    • (2006) J. Virol. , vol.80 , pp. 3617-3623
    • Martinez-picado, J.1
  • 52
    • 1842614416 scopus 로고    scopus 로고
    • + T cells: correlation with viral load
    • + T cells: correlation with viral load. J. Virol. 78:3233-3243.
    • (2004) J. Virol. , vol.78 , pp. 3233-3243
    • Masemola, A.1
  • 54
    • 77954617321 scopus 로고    scopus 로고
    • Long-term nonprogressive disease among untreated HIV-infected individuals: clinical implications of understanding immune control of HIV
    • Migueles SA, Connors M. 2010. Long-term nonprogressive disease among untreated HIV-infected individuals: clinical implications of understanding immune control of HIV. JAMA 304:194-201.
    • (2010) JAMA , vol.304 , pp. 194-201
    • Migueles, S.A.1    Connors, M.2
  • 55
    • 57449109484 scopus 로고    scopus 로고
    • + T cells is required for HIV-infected cell elimination associated with immune control
    • + T cells is required for HIV-infected cell elimination associated with immune control. Immunity 29:1009-1021.
    • (2008) Immunity , vol.29 , pp. 1009-1021
    • Migueles, S.A.1
  • 56
    • 0034646143 scopus 로고    scopus 로고
    • HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors
    • U.S.A.
    • Migueles SA, et al. 2000. HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors. Proc. Natl. Acad. Sci. U. S. A. 97:2709-2714.
    • (2000) Proc. Natl. Acad. Sci. , vol.97 , pp. 2709-2714
    • Migueles, S.A.1
  • 57
    • 70350322293 scopus 로고    scopus 로고
    • + T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy
    • + T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy. J. Virol. 83:11876-11889.
    • (2009) J. Virol. , vol.83 , pp. 11876-11889
    • Migueles, S.A.1
  • 58
    • 38449099323 scopus 로고    scopus 로고
    • Viral replication capacity as a correlate of HLA B57/B5801-associated nonprogressive HIV-1 infection
    • Navis M, et al. 2007. Viral replication capacity as a correlate of HLA B57/B5801-associated nonprogressive HIV-1 infection. J. Immunol. 179: 3133-3143.
    • (2007) J. Immunol. , vol.179 , pp. 3133-3143
    • Navis, M.1
  • 59
    • 0037225837 scopus 로고    scopus 로고
    • Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection
    • Novitsky V, et al. 2003. Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection. J. Virol. 77:882-890.
    • (2003) J. Virol. , vol.77 , pp. 882-890
    • Novitsky, V.1
  • 60
  • 61
    • 77950229250 scopus 로고    scopus 로고
    • Host determinants of HIV-1 control in African Americans
    • Pelak K, et al. 2010. Host determinants of HIV-1 control in African Americans. J. Infect. Dis. 201:1141-1149.
    • (2010) J. Infect. Dis. , vol.201 , pp. 1141-1149
    • Pelak, K.1
  • 62
    • 40049094957 scopus 로고    scopus 로고
    • Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy
    • Pereyra F, et al. 2008. Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy. J. Infect. Dis. 197:563-571.
    • (2008) J. Infect. Dis. , vol.197 , pp. 563-571
    • Pereyra, F.1
  • 63
    • 78650084232 scopus 로고    scopus 로고
    • The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
    • Pereyra F, et al. 2010. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science 330:1551-1557.
    • (2010) Science , vol.330 , pp. 1551-1557
    • Pereyra, F.1
  • 64
    • 20944447214 scopus 로고    scopus 로고
    • The immune epitope database and analysis resource: from vision to blueprint
    • doi:10.1371/journal. pbio.0030091
    • Peters B, et al. 2005. The immune epitope database and analysis resource: from vision to blueprint. PLoS Biol. 3:e91. doi:10.1371/journal. pbio.0030091.
    • (2005) PLoS Biol. , vol.3
    • Peters, B.1
  • 66
    • 41149160165 scopus 로고    scopus 로고
    • + T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy
    • + T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy. J. Virol. 82:3391-3404.
    • (2008) J. Virol. , vol.82 , pp. 3391-3404
    • Rehr, M.1
  • 67
    • 79961008229 scopus 로고    scopus 로고
    • + T cells from HIV controllers
    • + T cells from HIV controllers. Blood 118:955-964.
    • (2011) Blood , vol.118 , pp. 955-964
    • Sáez-cirión, A.1
  • 68
    • 34249852256 scopus 로고    scopus 로고
    • HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
    • U.S.A.
    • Sáez-Cirión A, et al. 2007. HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype. Proc. Natl. Acad. Sci. 104:6776-6781.
    • (2007) Proc. Natl. Acad. Sci. , vol.104 , pp. 6776-6781
    • Sáez-cirión, A.1
  • 70
    • 67649213034 scopus 로고    scopus 로고
    • Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses
    • Sáez-Cirión A, et al. 2009. Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses. J. Immunol. 182:7828-7837.
    • (2009) J. Immunol. , vol.182 , pp. 7828-7837
    • Sáez-cirión, A.1
  • 71
    • 63849131879 scopus 로고    scopus 로고
    • Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
    • Scheid JF, et al. 2009. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature 458:636-640.
    • (2009) Nature , vol.458 , pp. 636-640
    • Scheid, J.F.1
  • 72
    • 0033524838 scopus 로고    scopus 로고
    • + lymphocytes
    • + lymphocytes. Science 283:857-860.
    • (1999) Science , vol.283 , pp. 857-860
    • Schmitz, J.E.1
  • 73
    • 69249203739 scopus 로고    scopus 로고
    • Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infant
    • Schneidewind A, et al. 2009. Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infant. J. Virol. 83:8616-8627.
    • (2009) J. Virol. , vol.83 , pp. 8616-8627
    • Schneidewind, A.1
  • 74
    • 0142092653 scopus 로고    scopus 로고
    • Optimization of methods to assess human mucosal T-cell responses to HIV infection
    • Shacklett BL, et al. 2003. Optimization of methods to assess human mucosal T-cell responses to HIV infection. J. Immunol. Methods 279: 17-31.
    • (2003) J. Immunol. Methods , vol.279 , pp. 17-31
    • Shacklett, B.L.1
  • 75
    • 33344464667 scopus 로고
    • Measurement of diversity
    • Simpson EH. 1949. Measurement of diversity. Nature 163:688.
    • (1949) Nature , vol.163 , pp. 688
    • Simpson, E.H.1
  • 76
    • 44449096577 scopus 로고    scopus 로고
    • + T cells
    • doi:10.1371/journal.pmed.0050100
    • + T cells. PLoS Med. 5:e100. doi:10.1371/journal.pmed.0050100.
    • (2008) PLoS Med. , vol.5
    • Streeck, H.1
  • 77
    • 67650924875 scopus 로고    scopus 로고
    • + T cells
    • + T cells. J. Virol. 83:7641-7648.
    • (2009) J. Virol. , vol.83 , pp. 7641-7648
    • Streeck, H.1
  • 78
    • 34447259551 scopus 로고    scopus 로고
    • + T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles
    • + T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles. J. Virol. 81:7725-7731.
    • (2007) J. Virol. , vol.81 , pp. 7725-7731
    • Streeck, H.1
  • 79
    • 77957584418 scopus 로고    scopus 로고
    • T cell immunity in acute HIV-1 infection
    • Streeck H, Nixon DF. 2010. T cell immunity in acute HIV-1 infection. J. Infect. Dis. 202(Suppl. 2):S302-S308.
    • (2010) J. Infect. Dis. , vol.202 , Issue.SUPPL. 2
    • Streeck, H.1    Nixon, D.F.2
  • 80
    • 33646472100 scopus 로고    scopus 로고
    • + T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently
    • + T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently. J. Immunol. 176:6130-6146.
    • (2006) J. Immunol. , vol.176 , pp. 6130-6146
    • Turnbull, E.L.1
  • 81
    • 67449119122 scopus 로고    scopus 로고
    • Kinetics of expansion of epitope-specific T cell responses during primary HIV-1 infection
    • Turnbull EL, et al. 2009. Kinetics of expansion of epitope-specific T cell responses during primary HIV-1 infection. J. Immunol. 182:7131-7145.
    • (2009) J. Immunol. , vol.182 , pp. 7131-7145
    • Turnbull, E.L.1
  • 82
    • 59649108841 scopus 로고    scopus 로고
    • + T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1
    • + T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1. J. Virol. 83:1845-1855.
    • (2009) J. Virol. , vol.83 , pp. 1845-1855
    • Wang, Y.E.1
  • 83
    • 0023224968 scopus 로고
    • Bi-specific monoclonal antibodies: selective binding and complement fixation to cells that express two different surface antigens
    • Wong JT, Colvin RB. 1987. Bi-specific monoclonal antibodies: selective binding and complement fixation to cells that express two different surface antigens. J. Immunol. 139:1369-1374.
    • (1987) J. Immunol. , vol.139 , pp. 1369-1374
    • Wong, J.T.1    Colvin, R.B.2
  • 84
    • 0026088887 scopus 로고
    • + T cell subsets with bispecific monoclonal antibodies: evidence for inter-T cell-mediated cytolysis
    • + T cell subsets with bispecific monoclonal antibodies: evidence for inter-T cell-mediated cytolysis. Clin. Immunol. Immunopathol. 58:236-250.
    • (1991) Clin. Immunol. Immunopathol. , vol.58 , pp. 236-250
    • Wong, J.T.1    Colvin, R.B.2
  • 85
    • 70350221713 scopus 로고    scopus 로고
    • Candidate vaccine sequences to represent intraand inter-clade HIV-1 variation
    • doi:10.1371/journal. pone.0007388
    • Yang OO. 2009. Candidate vaccine sequences to represent intraand inter-clade HIV-1 variation. PLoS One 4:e7388. doi:10.1371/journal. pone.0007388.
    • (2009) PLoS One , vol.4
    • Yang, O.O.1
  • 86
    • 29744442730 scopus 로고    scopus 로고
    • Genetic and stochastic influences on the interaction of human immunodeficiency virus type 1 and cytotoxic T lymphocytes in identical twins
    • Yang OO, et al. 2005. Genetic and stochastic influences on the interaction of human immunodeficiency virus type 1 and cytotoxic T lymphocytes in identical twins. J. Virol. 79:15368-15375.
    • (2005) J. Virol. , vol.79 , pp. 15368-15375
    • Yang, O.O.1
  • 87
    • 79953736214 scopus 로고    scopus 로고
    • Increasing CTL targeting of conserved sequences during early HIV-1 infection is correlated to decreasing viremia
    • Yang OO, Daar ES, Ng HL, Shih R, Jamieson BD. 2011. Increasing CTL targeting of conserved sequences during early HIV-1 infection is correlated to decreasing viremia. AIDS Res. Hum. Retroviruses 27:391-398.
    • (2011) AIDS Res. Hum. Retroviruses , vol.27 , pp. 391-398
    • Yang, O.O.1    Daar, E.S.2    Ng, H.L.3    Shih, R.4    Jamieson, B.D.5


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