-
1
-
-
56649105122
-
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
-
Buchbinder SP, Mehrotra DV, Duerr A, Fitzgerald DW, Mogg R, Li D, et al. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 2008; 372: 1881-1893.
-
(2008)
Lancet
, vol.372
, pp. 1881-1893
-
-
Buchbinder, S.P.1
Mehrotra, D.V.2
Duerr, A.3
Fitzgerald, D.W.4
Mogg, R.5
Li, D.6
-
2
-
-
56649111197
-
Failure of the Merck HIV vaccine: An uncertain step forward
-
Robb ML. Failure of the Merck HIV vaccine: an uncertain step forward. Lancet 2008; 372:1857-1858.
-
(2008)
Lancet
, vol.372
, pp. 1857-1858
-
-
Robb, M.L.1
-
3
-
-
56649114351
-
HIV-1 vaccine-induced immunity in the test-of-concept Step Study: A case-cohort analysis
-
McElrath MJ, De Rosa SC, Moodie Z, Dubey S, Kierstead L, Janes H, et al. HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis. Lancet 2008; 372:1894-1905.
-
(2008)
Lancet
, vol.372
, pp. 1894-1905
-
-
McElrath, M.J.1
De Rosa, S.C.2
Moodie, Z.3
Dubey, S.4
Kierstead, L.5
Janes, H.6
-
4
-
-
50849126803
-
HIV vaccine development in the aftermath of the STEP study: Re-focus on occult HIV infection?
-
Uberla K. HIV vaccine development in the aftermath of the STEP study: re-focus on occult HIV infection? PLoS Pathog 2008; 4:e1000114.
-
(2008)
PLoS Pathog
, vol.4
-
-
Uberla, K.1
-
5
-
-
58149293629
-
Activation of a dendritic cell-T cell axis by Ad5 immune complexes creates an improved environment for replication of HIV in T cells
-
Perreau M, Pantaleo G, Kremer EJ. Activation of a dendritic cell-T cell axis by Ad5 immune complexes creates an improved environment for replication of HIV in T cells. J Exp Med 2008; 205:2717-2725.
-
(2008)
J Exp Med
, vol.205
, pp. 2717-2725
-
-
Perreau, M.1
Pantaleo, G.2
Kremer, E.J.3
-
6
-
-
42149137535
-
Impact of recombinant adenovirus serotype 35 priming versus boosting of a Plasmodium falciparum protein: Characterization of T- and B-cell responses to liver-stage antigen 1
-
Rodriguez A, Goudsmit J, Companjen A, Mintardjo R, Gil-lissen G, Tax D, et al. Impact of recombinant adenovirus serotype 35 priming versus boosting of a Plasmodium falciparum protein: characterization of T- and B-cell responses to liver-stage antigen 1. Infect Immun 2008; 76: 1709-1718.
-
(2008)
Infect Immun
, vol.76
, pp. 1709-1718
-
-
Rodriguez, A.1
Goudsmit, J.2
Companjen, A.3
Mintardjo, R.4
Gil-Lissen, G.5
Tax, D.6
-
7
-
-
32144439525
-
Development of adenoviral-vector-based pandemic influenza vaccine against antigenically distinct human H5N1 strains in mice
-
Hoelscher MA, Garg S, Bangari DS, Belser JA, Lu X, Stephenson I, et al. Development of adenoviral-vector-based pandemic influenza vaccine against antigenically distinct human H5N1 strains in mice. Lancet 2006; 367:475-481.
-
(2006)
Lancet
, vol.367
, pp. 475-481
-
-
Hoelscher, M.A.1
Garg, S.2
Bangari, D.S.3
Belser, J.A.4
Lu, X.5
Stephenson, I.6
-
8
-
-
8444222278
-
Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis
-
Wang J, Thorson L, Stokes RW, Santosuosso M, Huygen K, Zganiacz A, et al. Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis. J Immunol 2004; 173:6357-6365.
-
(2004)
J Immunol
, vol.173
, pp. 6357-6365
-
-
Wang, J.1
Thorson, L.2
Stokes, R.W.3
Santosuosso, M.4
Huygen, K.5
Zganiacz, A.6
-
9
-
-
0034735774
-
Development of a preventive vaccine for Ebola virus infection in primates
-
Sullivan NJ, Sanchez A, Rollin PE, Yang ZY, Nabel GJ. Development of a preventive vaccine for Ebola virus infection in primates. Nature 2000; 408:605-609.
-
(2000)
Nature
, vol.408
, pp. 605-609
-
-
Sullivan, N.J.1
Sanchez, A.2
Rollin, P.E.3
Yang, Z.Y.4
Nabel, G.J.5
-
11
-
-
70449629857
-
OA05-06 LB First-in-human phase 1 safety and immu-nigenicity of an adenovirus serotype 26 HIV-1 vaccine vector
-
Baden L, Dolin R, O'Brien K, Abbink P, La Porte A, Seaman M, et al. OA05-06 LB. First-in-human phase 1 safety and immu-nigenicity of an adenovirus serotype 26 HIV-1 vaccine vector. Retrovirology 2009; 6:O36.
-
(2009)
Retrovirology
, vol.6
-
-
Baden, L.1
Dolin, R.2
O'Brien, K.3
Abbink, P.4
La Porte, A.5
Seaman, M.6
-
12
-
-
37549033167
-
One step forward, two steps back: Will there ever be an AIDS vaccine?
-
Steinbrook R. One step forward, two steps back: will there ever be an AIDS vaccine? N Engl J Med 2007; 357:2653-2655.
-
(2007)
N Engl J Med
, vol.357
, pp. 2653-2655
-
-
Steinbrook, R.1
-
13
-
-
48249134364
-
HIV vaccine research: The way forward
-
Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie JA, et al. HIV vaccine research: the way forward. Science 2008; 321:530-532.
-
(2008)
Science
, vol.321
, pp. 530-532
-
-
Fauci, A.S.1
Johnston, M.I.2
Dieffenbach, C.W.3
Burton, D.R.4
Hammer, S.M.5
Hoxie, J.A.6
-
14
-
-
38749096240
-
The failed HIV Merck vaccine study: A step back or a launching point for future vaccine development?
-
Sekaly RP. The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? J Exp Med 2008; 205:7-12.
-
(2008)
J Exp Med
, vol.205
, pp. 7-12
-
-
Sekaly, R.P.1
-
15
-
-
0037771077
-
Replication-deficient human adeno-virus type 35 vectors for gene transfer and vaccination: Efficient human cell infection and bypass of preexisting adenovirus immunity
-
Vogels R, Zuijdgeest D, van Rijnsoever R, Hartkoorn E, Damen I, de Bethune MP, et al. Replication-deficient human adeno-virus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity. J Virol 2003; 77:8263-8271.
-
(2003)
J Virol
, vol.77
, pp. 8263-8271
-
-
Vogels, R.1
Zuijdgeest, D.2
Van Rijnsoever, R.3
Hartkoorn, E.4
Damen, I.5
De Bethune, M.P.6
-
16
-
-
34247585475
-
Comparative seroprevalence and immunogeni-city of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D
-
Abbink P, Lemckert AA, Ewald BA, Lynch DM, Denholtz M, Smits S, et al. Comparative seroprevalence and immunogeni-city of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D. J Virol 2007; 81:4654-4663.
-
(2007)
J Virol
, vol.81
, pp. 4654-4663
-
-
Abbink, P.1
Lemckert, A.A.2
Ewald, B.A.3
Lynch, D.M.4
Denholtz, M.5
Smits, S.6
-
17
-
-
34247623684
-
Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa
-
Thorner AR, Vogels R, Kaspers J, Weverling GJ, Holterman L, Lemckert AA, et al. Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa. J Clin Microbiol 2006; 44:3781-3783.
-
(2006)
J Clin Microbiol
, vol.44
, pp. 3781-3783
-
-
Thorner, A.R.1
Vogels, R.2
Kaspers, J.3
Weverling, G.J.4
Holterman, L.5
Lemckert, A.A.6
-
18
-
-
68349135329
-
Adenovirus-specific immunity after immunization with an Ad5 HIV-1vaccinecandidateinhumans
-
O'Brien KL, Liu J, King SL, Sun YH, Schmitz JE, Lifton MA, et al. Adenovirus-specific immunity after immunization with an Ad5 HIV- 1vaccinecandidateinhumans.NatMed2009;15:873-875.
-
(2009)
Nat Med
, vol.15
, pp. 873-875
-
-
O'Brien, K.L.1
Liu, J.2
King, S.L.3
Sun, Y.H.4
Schmitz, J.E.5
Lifton, M.A.6
-
19
-
-
68349130410
-
Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4R T cells
-
Hutnick NA, Carnathan DG, Dubey SA, Makedonas G, Cox KS, Kierstead L, et al. Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4R T cells. Nat Med 2009; 15:876-878.
-
(2009)
Nat Med
, vol.15
, pp. 876-878
-
-
Hutnick, N.A.1
Carnathan, D.G.2
Dubey, S.A.3
Makedonas, G.4
Cox, K.S.5
Kierstead, L.6
-
20
-
-
0023186650
-
The Multicenter AIDS Cohort Study: Rationale, organization, and selected characteristics of the participants
-
Kaslow RA, Ostrow DG, Detels R, Phair JP, Polk BF, Rinaldo CR Jr. The Multicenter AIDS Cohort Study: rationale, organization, and selected characteristics of the participants. Am J Epidemiol 1987; 126:310-318.
-
(1987)
Am J Epidemiol
, vol.126
, pp. 310-318
-
-
Kaslow, R.A.1
Ostrow, D.G.2
Detels, R.3
Phair, J.P.4
Polk, B.F.5
Rinaldo Jr., C.R.6
-
21
-
-
45249108765
-
Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: A randomised, double-blind, placebo-controlled trial
-
Celum C, Wald A, Hughes J, Sanchez J, Reid S, Delany-Mor-etlwe S, et al. Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial. Lancet 2008; 371:2109-2119.
-
(2008)
Lancet
, vol.371
, pp. 2109-2119
-
-
Celum, C.1
Wald, A.2
Hughes, J.3
Sanchez, J.4
Reid, S.5
Delany-Mor-Etlwe, S.6
-
22
-
-
12144291311
-
Quantitative adenovirus neutralization assays based on the secreted alkaline phosphatase reporter gene: Application in epidemiologic studies and in the design of adenovector vaccines
-
Aste-Amezaga M, Bett AJ, Wang F, Casimiro DR, Antonello JM, Patel DK, et al. Quantitative adenovirus neutralization assays based on the secreted alkaline phosphatase reporter gene: application in epidemiologic studies and in the design of adenovector vaccines. Hum Gene Ther 2004; 15:293-304.
-
(2004)
Hum Gene Ther
, vol.15
, pp. 293-304
-
-
Aste-Amezaga, M.1
Bett, A.J.2
Wang, F.3
Casimiro, D.R.4
Antonello, J.M.5
Patel, D.K.6
-
23
-
-
58149136160
-
Poststep modifications for research on HIV vaccines
-
Corey L, McElrath MJ, Kublin JG. Poststep modifications for research on HIV vaccines. AIDS 2009; 23:3-8.
-
(2009)
AIDS
, vol.23
, pp. 3-8
-
-
Corey, L.1
McElrath, M.J.2
Kublin, J.G.3
-
24
-
-
58149111811
-
Efficacy results from the Step Study (Merck V520 Protocol 023/HVTN 502): A phase II test-of-concept trial of the MRKAd5 HIV-1Gag/Pol/Nef Trivalent Vaccine
-
Boston MA: Hynes Convention Center
-
Buchbinder S. Efficacy results from the Step Study (Merck V520 Protocol 023/HVTN 502): a phase II test-of-concept trial of the MRKAd5 HIV-1Gag/Pol/Nef Trivalent Vaccine. 15th Conference on Retroviruses and Opportunistic Infections. Boston, MA: Hynes Convention Center; 2008.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections
-
-
Buchbinder, S.1
|