Graptopetalum paraguayense and resveratrol ameliorates carboxymethyllysine (CML)-induced pancreas dysfunction and hyperglycemia

Food and Chemical Toxicology

Volumn 62, Issue , 2013, Pages 492-498

  Lee, Bao Hong ^a   Lee, Chia Chen ^a   Cheng, Yu Hsiang ^b   Chang, Wen Chang ^a   Hsu, Wei Hsuan ^a   Wu, She Ching ^a  

^a NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Carboxymethyllysine (CML); Graptopetalum paraguayense; Insulin sensitivity; Nuclear factor erythroid2 related factor 2 (Nrf2); Peroxisome proliferator activated receptor (PPAR ); Resveratrol

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ALCOHOL; ANTIOXIDANT; CCAAT ENHANCER BINDING PROTEIN BETA; GALLIC ACID; GLUCOSE; GRAPTOPETALUM PARAGUAYENSE EXTRACT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLANT EXTRACT; RESVERATROL; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GLYCEMIC CONTROL; GRAPTOPETALUM PARAGUAYENSE; HYPERGLYCEMIA; INSULIN SENSITIVITY; INSULIN SYNTHESIS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS INSUFFICIENCY; PLANT LEAF; PROTEIN EXPRESSION; UPREGULATION; VEGETABLE;

GRAPTOPETALUM PARAGUAYENSE; MUS;

CARBOXYMETHYLLYSINE (CML); GRAPTOPETALUM PARAGUAYENSE; INSULIN SENSITIVITY; NUCLEAR FACTOR-ERYTHROID2-RELATED FACTOR 2 (NRF2); PEROXISOME PROLIFERATOR ACTIVATED-RECEPTOR-Γ (PPARΓ); RESVERATROL;

ANIMALS; CRASSULACEAE; GALLIC ACID; HOMEODOMAIN PROTEINS; HYPERGLYCEMIA; INSULIN; LIVER; LYSINE; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PANCREAS; PLANT EXTRACTS; PPAR GAMMA; STILBENES; TAIWAN; TRANS-ACTIVATORS;

EID: 84884944623     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.09.005     Document Type: Article

References (43)

1. Bonnefont-Rousselot D. Glucose and reactive oxygen species. Current Opinion in Clinical Nutrition and Metabolism Care 2002, 5:561-568.
2. Brissova M., Blaha M., Spear C. Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis. American Journal of Physiology-Endocrinology and Metabolism 2005, 288:E707-E714.
3. Bruckbauer A., Zemel M.B. Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity. Diabetes, Metabolic Syndrome and Obesity 2013, 6:93-102.
4. Buetler T.M., Leclerc E., Baumeyer A., Latado H., Newell J., Adolfsson O., Parisod V., Richoz J., Maurer S., Foata F., Piguet D., Junod S., Heizmann C.W., Delatour T. N-Carboxymethyllysine-medified proteins are unable to bind to RAGE and activate an inflammatory response. Molecular Nutrition and Food Chemistry 2008, 52:370-378.
5. Chen S., Li J., Zhang Z., Li W., Sun Y., Zhang Q., Feng X., Zhu W. Effects of resveratrol on the amelioration of insulin resistance in KKAy mice. Canada Journal of Physiology and Pharmacology 2012, 90:237-242.
6. Cheng A.S., Cheng Y.H., Chiou C.H., Chang T.L. Resveratrol upregulates Nrf2 expression to attenuate methylglyoxal-induced insulin resistance in Hep G2 cells. Journal of Agricultural and Food Chemistry 2012, 60:9180-9187.
7. Day J.F., Thorpe S.R., Baynes J.W. Non enzymatically glucosylated albumin: in vitro preparation and isolation from normal human serum. Journal of Biological Chemistry 1979, 254:595-597.
8. Dhar A., Desai K.M., Wu L. Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats. British Journal of Pharmacology 2010, 159:166-175.
9. Dhar A., Dhar I., Jiang B., Desai K.M., Wu L. Chronic methylglyoxal infusion by minipump causes pancreatic β-cell dysfunction and induces type 2 diabetes in Sprague-Dawley Rats. Diabetes 2011, 60:899-908.
10. 4-induced liver damage and inflammation. Journal of Ethnpharmacology 2011, 134:379-385.
11. Guha M., Bai W., Nadler J.L., Natarajan R. Molecular mechanisms of tumor necrosis factor alpha gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and -independent pathways. Journal of Biological Chemistry 2000, 275:17728-17739.
12. Gupta D., Jetton T.L., Mortensen R.M., Duan S.Z., Peshavaria M., Leahy J.L. In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor-γ response element in the mouse pdx-1 promoter. Journal of Biological Chemistry 2008, 283:32462-32470.
13. Huang S.M., Wu C.H., Yen G.C. Effects of flavonoids on the expression of the pro-inflammatory response in human monocytes induced by ligation of the receptor for AGEs. Molecular Nutrition and Food Research 2006, 50:1129-1139.
14. Irwin N., McKinney J.M., Bailey C.J., McClenaghan N.H., Flatt P.R. Acute and long-term effects of peroxisome proliferator-activated receptor-γ activation on the function and insulin secretory responsiveness of clonal beta-cells. Hormone and Metabolism Research 2011, 43:244-249.
15. Kajimoto Y., Kaneto H. Role of oxidative stress in pancreatic beta-cell dysfunction. Annals of the New York Academy of Sciences 2004, 1011:168-176.
16. Kaneto H., Miyatsuka T., Kawamori D. PDX-1 and Maf-A play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function. Endocrine Journal 2008, 55:235-252.
17. Keum Y.S., Owuor E.D., Kim B.R., Hu R., Kong A.N. Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC). Pharmacy Research 2003, 20:1351-1356.
18. Lee B.H., Hsu W.H., Chang Y.Y., Kuo H.F., Hsu Y.W., Pan T.M. Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. Free Radical Biology and Medicine 2012, 53:2008-2016.
19. Lee B.H., Huang Y.Y., Duh P.D., Wu S.C. Hepatoprotection of emodin and polygonum multiflorum against CCl4-indued liver injury. Pharmaceutical Biology 2012, 50:351-359.
20. Lee B.H., Hsu W.H., Hsu Y.W., Pan T.M. Dimerumic acid protects pancreas damage and elevates insuin production in methylglyoxal-treated pancreatic RINm5F cells. Journal of Functional Foods 2013, 5:642-650.
21. Lin J.A., Fang S.C., Wu C.H., Huang S.M., Yen G.C. Anti-inflammatory effect of the 5,4-trihydroxy-6-geranylflavanone isolated from the fruit of Artocarpus communis in S100B-induced human monocytes. Journal of Agricultural and Food Chemistry 2011, 59:105-111.
22. Moibi J.A., Gupta D., Jetton T.L., Peshavaria M., Desai R., Leahy J.L. Peroxisome proliferator-activated receptor-γ regulates expression of PDX-1 and NKX6.1 in INS-1 cells. Diabetes 2007, 56:88-95.
23. Negre-Salvayre A., Salvayre R., Auge N., Pamplona R., Portero-Otin M. Hyperglycemia and glycation in diabetic complications. Antioxidation and Redox Signaling 2009, 11:3071-3109.
24. 2. Molecular and Cellular Biochemistry 2012, 371:9-22.
25. Santos C.X., Tanaka L.Y., Wosniak J., Laurindo F.R. Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase. Antioxidant and Redox Signaling 2009, 11:2409-2427.
26. Schiekofer S., Andrassy M., Chen J., Rudofsky G., Schneider J., Wendt T., Stefan N., Humpert P., Fritsche A., Stumvoll M., Schleicher E., Haring H.U., Nawroth P.P., Bierhaus A. Acute hyperglycemia causes intracellular formation of CML and activation of rasp42/44MAPK and nuclear factor kappaB in PBMCs. Diabetes 2003, 52:621-633.
27. Sheader E.A., Benson R.S.P., Best L. Cytotoxic action of methylglyoxal on insulin-secreting cells. Biochemical Pharmacology 2001, 61:1381-1386.
28. Shu T., Zhu Y., Wang H., Lin T., Ma Z., Han X. AGEs decrease insulin synthesis in pancreatic beta-cell by repressing PDX-1 protein expression at the post-translational level. PLoS One 2011, 6:e18782.
29. Stephen I.S., Sunil C., Duraipandiyan V., Ignacimuthu S. Antidiabetic and antioxidant activities of Toddalia asiatica (L.) Lam. leaves in streptozotocin induced diabetic rats. Journal of Ethnopharmacology 2012, 143:515-523.
30. Su L.J., Yang C.H., You S.F., Huang Y.L., Hsieh H.C., Tseng T.L., Chen C.H., Hsu S.L., Huang C.Y. Evaluation of the Chinese medicinal herb, Graptopetalum paraguayense, as a therapeutic treatment for liver damage in rat models. Evidence-Based Complementary Alternative Medicine 2012, Article 256561.
31. Su L.J., Chang C.C., Yang C.H., Hsieh S.J., Wu Y.C., Lai J.M., Tseng T.L., Huang C.Y., Hsu S.L. Graptopetalum paraguayense ameliorates chemical-induced rat hepatic fibrosis in vivo and inactivates stellate cells and kupffer cells in vitro. PLoS One 2013, 2013:e53988.
32. Surh Y.J. NFκB and Nrf2 as potential chemopreventive targets of some anti-inflammatory and antioxidative phytonutrients with anti-inflammatory and antioxidative activities. Asia Pacific Journal of Clinical Nutrition 2008, 17:269-272.
33. Wang Q., Somwar R., Bilan P.J., Liu Z., Jin J., Woodgett J.R., Klip A. Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts. Molecular and Cellular Biology 1999, 19:4008-4018.
34. Wang S.H., Chang J.C., Pokkaew R., Lee J.F., Chiou Y.Y. Modified fast procedure for the detection and screening of antiglycative phytochemicals. Journal of Agricultural and Food Chemistry 2011, 59:6906-6912.
35. Weng C.J., Chen M.J., Yeh C.T., Yen G.C. Hepatoprotection of quercetin against oxidative stress by induction of metallothionein expression through activating MAPK and PI3K pathways and enhancing Nrf2 DNA-binding activity. Nature Biotechnology 2011, 28:767-777.
36. Wu C.H., Huang S.M., Lin J.A., Yen G.C. Inhibition of advanced glycation endproduct formation by foodstuffs. Food and Function 2011, 2:224-234.
37. Wu S.C., Su Y.S., Cheng H.Y. Antioxidant properties of Lactobacillus-fermented and non-fermented Graptopetalum paraguayense E. Walther at different stages of maturity. Food Chemistry 2011, 129:804-809.
38. Xie W., Zhao Y., Gu D., Du L., Cai G., Zhang Y. Scorpion in combination with gypsum: novel antidiabetic activities in streptozotocin-indued diabetic mice by up-regulating pancreatic PPARgamma and PDX-1 expression. Evidence-Based Complementary Alternative Medicine 2011, 2011. Article 683561.
39. Xue M., Rabbani N., Momiji H., Imbasi P., Anwar-Maqsud M., Kitteringham N., Park-Kevin B., Souma T., Moriguchi T., Yamamoto M., Thornalley P.J. Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. Biochemistry Journal 2012, 443:213-222.
40. Yang C., Chang T.J., Chang J.C., Liu M.W., Tai T.Y., Hsu H.W., Chuang L.M. Rosiglitazone (BRL 49653) enhances insulin secretory response via phosphatidylinositol-3-kinase pathway. Diabetes 2001, 50:2598-2602.
41. Yeh C.T., Yen G.C. Induction of hepatic antioxidant enzymes by phenolic acids in rats is accompanied by increased levels of multidrug resistance-associated protein 3 mRNA expression. Journal of Nutrition 2006, 136:11-15.
42. Zhang Y., Luo Z., Ma L., Xu Q., Yang Q., Si L. Resveratrol prevents the impairment of advanced glycasylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor gamma activation. International Journal of Molecular Medicine 2010, 25:729-734.
43. Zhao X., Zhao C., Zhang X.H., Zheng F., Cai W., Vlassara H., Ma A. Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis. Endocrinology 2009, 150:2569-2576.