Antidiabetic and antioxidant activities of Toddalia asiatica (L.) Lam. leaves in Streptozotocin induced diabetic rats

Journal of Ethnopharmacology

Volumn 143, Issue 2, 2012, Pages 515-523

  Stephen Irudayaraj, Santiagu ^a   Sunil, Christudas ^a   Duraipandiyan, Veeramuthu ^a,b   Ignacimuthu, Savarimuthu ^a  

^a LOYOLA COLLEGE   (India)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Diabetes mellitus; OGTT; Streptozotocin; Toddalia asiatica

Indexed keywords

ANTIDIABETIC AGENT; ANTIOXIDANT; FLINDERSINE; GLIBENCLAMIDE; GLUCOSE; GLUTATHIONE PEROXIDASE; GLYCOGEN; INSULIN; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PROTEIN; SUPEROXIDE DISMUTASE; TODDALIA ASIATICA EXTRACT; ULOPTEROL; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; DRUG SCREENING; GLUCOSE BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; INSULIN BLOOD LEVEL; MALE; MEDICINAL PLANT; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PLANT LEAF; RAT; RUTACEAE; STREPTOZOCIN DIABETES; TODDALIA ASIATICA;

ACETATES; ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; BLOOD GLUCOSE; CATALASE; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE TOLERANCE TEST; GLUTATHIONE PEROXIDASE; GLYCOGEN; HYPOGLYCEMIC AGENTS; INSULIN; MALE; PANCREAS; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; RUTACEAE; SOLVENTS; SUPEROXIDE DISMUTASE;

RATTUS; TODDALIA ASIATICA;

EID: 84866032128     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.07.006     Document Type: Article

References (46)

1. T.P. Almadal, and H. Vilstrup Strict insulin treatment normalizes the organic nitrogen contents and the capacity of urea-N synthesis in experimental diabetes in rats Diabetologica 31 1988 114 118
2. N.V. Carroll, R.W. Longley, and J.H. Roe The determination of glycogen in liver and muscle by use of anthrone reagent Journal of Biological Chemistry 220 1956 583 593
3. A. Ceriello Postprandial hyperglycemia and diabetes complications: is it time to treat? Diabetes 54 2005 1 7
4. G. Chandramohan, S. Ignacimuthu, and K.V. Pugalendi A novel compound from Casearia esculenta (Roxb.) root and its effect on carbohydrate metabolism in streptozotocin diabetic rats European Journal of Pharmacology 590 2008 437 443
5. Chopra, R.N.; Nayar, S.L.; Chopra, I.C.; 1956. Glossary of Indian Medicinal plants, New Delhi.
6. A.B. Deore, V.D. Sapakal, and N.S. Naikwade Role of oxidative stress in pathogenesis of diabetes and its complications Pharmacologyonline 2 2011 603 621
7. S. Dewanjee, A.K. Das, R. Sahu, and M. Gangopadhyay Antidiabetic activity of Diospyros peregrine fruit: effect on hyperglycemia, hyperlipidemia and augmented oxidative stress in experimental type 2 diabetes Food and Chemical Toxicology 47 2009 2679 2685
8. V. Duraipandiyan, M. Ayyanar, and S. Ignacimuthu Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India BMC Complementary and Alternative Medicine 6 2006 1 7
9. V. Duraipandiyan, and S. Ignacimuthu Antibacterial and antifungal activity of Flindersine isolated from the traditional medicinal plant, Toddalia asiatica (L.) Lam Journal of Ethnopharmacology 123 2009 494 498
10. J. Eliza, P. Daisy, and S. Ignacimuthu Antioxidant activity of costunolide and eremanthin isolated from Costus speciosus (Koen ex. Retz) Sm Chemico-Biological Interactions 188 2010 467 472
11. T. Gohil, N. Pathak, N. Jivani, V. Devmurari, and J. Patel Treatment with extracts of Eugenia jambolana seed and Aegle marmelos leaf extracts prevents hyperglycemia and hyperlipidemia in alloxan induced diabetic rats African Journal of Pharmacy and Pharmacology 4 2010 270 275
12. B. Halliwell, and J.M. Gutteridge Free Radical in Biology and Medicine 1999 Oxford University Press UK
13. J.B. Harborne Phytochemical Methods 1998 Chapman and Hall London (60 pp.)
14. S. Hemalatha, T. Ayyappan, S. Shanmugam, D. Nagavalli, and T. Shrivijaya Kirubha Evaluation of antidiabetic and diuretic activity of polyherbal formulation Indian Journal of Traditional Knowledge 5 2006 468 470
15. G.I. Humason Animal Tissue Techniques 1979 Freeman and Company San Francisco
16. P. Kakkar, B. Dos, and P.N. Viswanathan A modified spectrophotometric assay of superoxide dismutase Indian Journal of Biochemistry and Biophysics 21 1984 130 132
17. M. Karunai Raj, C. Balachandran, V. Duraipandiyan, P. Agastian, and S. Ignacimuthu Antimicrobial activity of Ulopterol isolated from Toddalia asiatica (L.) Lam.: a traditional medicinal plant Journal of Ethnopharmacology 140 2012 161 165
18. R.B. Kasetti, M.D. Rajasekhar, V.K. Kondeti, S.S. Fatima, E.G.T. Kumar, S. Swapna, R. Bellamkonda, and R. Chippada Appa Antihyperglycemic and antihyperlipidemic activities of methanol:water (4:1) fraction isolated from aqueous extract of Syzgium alternifolium seeds in streptozotocin induced diabetic rats Food and Chemical Toxicology 48 2010 1078 1084
19. A.L. Kennedy, and T.J. Lyons Glycation, oxidation and lipoxidation in the development of diabetic complications Metabolism 46 1997 14 21
20. P.R.N. Kind, and E.J. King Estimation of plasma phosphatases by determination of hydrolyzed phenol with amino-antipyrine Journal of Clinical Pathology 7 1954 322 330
21. J.O. Kokwaro Medicinal Plants of East Africa 1993 East African Literature Bureau Nairobi (212 pp.)
22. K.R. Kritikar, and B.D. Basu Indian Medicinal Plants vol. 1 1987 International book distributors Dehradun (468 pp.)
23. W. Kusirisin, C. Jaikang, C. Chaiyasut, and P. Narongchai Effect of polyphenolic compounds from Solanum torvum on plasma lipid peroxidation, superoxide anion and cytochrome P450 2E1 in human liver microsomes Medicinal Chemistry 5 2009 583 588
24. O.H. Lowry, N.J. Rosenbrough, and A.L. Farr Protein measurement with Folin-phenol reagent Journal of Biological Chemistry 193 1951 265 275
25. R.J. Marles, and N.R. Farnsworth Antidiabetic plants and their active constituents Phytomedicine 2 1995 137 189
26. P. Muthumani, R. Meera, P. Devi, S.A. Mohamed, S. Arabath, L.V. Seshu Kumar Koduri, and S. Manavarthi Chemical investigation of Toddalia asiatica Lin. and Cardiospermum halicacabum Lin International Journal of Drug Formulation and Research 1 2010 224 239
27. H.C. Oliveira, M.P. Dos Santos, R. Grigulo, L.L. Lima, D.T.O. Martins, J.C.S. Lima, L.F. Stoppiglia, C.F. Lopes, and N.F. Kawashita Antidiabetic activity of Vatairea macrocarpa extract in rats Journal of Ethnopharmacology 115 2008 515 519
28. L. Pari, and N. Rajarajeswari Efficacy of coumarin on hepatic key enzymes of glucose metabolism in chemical induced type 2 diabetic rats Chemico-Biological Interactions 181 2009 292 296
29. T. Pullaiah, and K. Chandrasekhar Naidu Antidiabetic Plants in India and Herbal Based Antidiabetic Research 2003 Regency Publications New Delhi (303 pp.)
30. R. Punitha, and S. Manohara Antihyperglycemic and antilipidperoxidative effects of Pongamia pinnata (Linn.) Pierre flowers in alloxan induced diabetic rats Journal of Ethnopharmacology 105 2006 39 46
31. K.M. Ramkumar, C. Manjula, L. Sankar, S. Suriyanarayanan, and P. Rajaguru Potential in vitro antioxidant and protective effects of Gymnema montanum H. on alloxan-induced oxidative damage in pancreatic β-cells, HIT-T15 Food and Chemical Toxicology 47 2009 2246 2256
32. M. Rajkumar, R.H. Chandra, and C. Veeresham Production of nitidine from callus cultures of Toddalia asiatica International Journal of Pharmaceutical Sciences and Nanotechnology 3 2010 1028 1033
33. S. Reitman, and S.A. Frankel Colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminases American Journal of Clinical Pathology 28 1957 56 63
34. J.T. Rotruck, A.L. Pope, H.E. Ganther, and A.B. Swason Selenium: biochemical role as a component of glutathione peroxidase Science 179 1973 588 590
35. M. Salahuddin, and S.S. Jalalpure Antidiabetic activity of aqueous fruit extract of Cucumis trigonus Roxb. in streptozotocin-induced diabetic rats Journal of Ethnopharmacology 127 2010 565 567
36. A. Shirwaikar, and K. Rajendran Effect of aqueous bark extract of Garuga pinnata Roxb. in streptozotocin-nicotinamide induced type-II diabetes mellitus Journal of Ethnopharmacology 112 2006 1 6
37. V.L. Singleton, and J.A. Rossi Colorimetry of total phenolics with phosphomolybdic reagents American Journal of Enology and Viticulture 16 1965 144 158
38. S. Singh, Y.K. Loke, and C.D. Furberg Thiazolidinediones and heart failure: a teleo-analysis Diabetes Care 8 2007 2148 2153
39. K.A. Sinha Colorimetric assay of catalase Analytical Biochemistry 47 1972 389 394
40. C. Slot Plasma creatinine determination. A new and specific Jaffe reaction method Scandinavian Journal of Clinical & Laboratory Investigation 17 1965 381 387
41. C. Sunil, P. Agastian, and I. Ignacimuthu In vitro antioxidant, antidiabetic and antilipidemic activities of Symplocos cochinchinensis (Lour.) S. Moore. bark Food and Chemical Toxicology 50 2012 1547 1553
42. T. Tuvemo, U. Ewald, M. Kobboh, and L.A. Proos Serum magnesium and protein concentrations during the first five years of insulin dependent diabetes in children Acta Paediatrica Supplement 418 1997 7 10
43. A. Umar, Q.U. Ahmed, B.Y. Muhammad, B.B. Dogarai, and S.Z. Soad Anti-hyperglycemic activity of the leaves of Tetracera scandens Linn. Merr. (Dilleniaceae) in alloxan induced diabetic rats Journal of Ethnopharmacology 1 2010 140 145
44. F. Wang, Y. Xub, and J. Liua New geranyloxycoumarins from Toddalia asiatica Journal of Asian Natural Products Research. 11 2009 752 756
45. S.G. Wild, A. Roglic, R. Green, R. Sicree, and H. King Global prevalence of diabetes: estimated for the year 2000 and projection for 2030 Diabetes Care 5 2004 1047 1053
46. D.R. Wybenga, J. Di Giorgio, and V.J. Pileggi Manual and automated methods for urea nitrogen measurement in whole serum Clinical Chemistry 17 1971 891 895