MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells

Journal of Cellular Physiology

Volumn 227, Issue 9, 2012, Pages 3192-3200

  Yang, Guangdong ^a   Pei, Yanxi ^a,b   Cao, Qiuhui ^a   Wang, Rui ^a  

^a LAKEHEAD UNIVERSITY   (Canada)

^b SHANXI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTATHIONINE GAMMA LYASE; HYDROGEN SULFIDE; MICRORNA 21; MITHRAMYCIN; PROPARGYLGLYCINE; TRANSCRIPTION FACTOR SP1;

3' UNTRANSLATED REGION; AORTA MEDIA; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; ENZYME INHIBITION; ENZYME REPRESSION; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; RNA SYNTHESIS; SMOOTH MUSCLE FIBER;

ANIMALS; AORTA; CAROTID ARTERIES; CELL DIFFERENTIATION; CELL PROLIFERATION; CYSTATHIONINE GAMMA-LYASE; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; HYDROGEN SULFIDE; MICE; MICE, INBRED C57BL; MICRORNAS; MUSCLE, SMOOTH, VASCULAR; PLICAMYCIN; SP1 TRANSCRIPTION FACTOR;

EID: 84862094335     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24006     Document Type: Article

References (45)

1. Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC. 2010. MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol 30: 1118-1126.
2. Ambros V. 2004. The functions of animal microRNAs. Nature 431: 350-355.
3. Bartel DP. 2004. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
4. Bendeck MP, Zempo N, Clowes AW, Galardy RE, Reidy MA. 1994. Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat. Circ Res 75: 539-545.
5. Brennecke J, Stark A, Russell RB, Cohen SM. 2005. Principles of microRNA-target recognition. PLoS Biol 3: e85.
6. Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM, Conlon FL, Wang DZ. 2006. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 38: 228-233.
7. Cheng AM, Byrom MW, Shelton J, Ford LP. 2005. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 33: 1290-1297.
8. Cheng Y, Ji R, Yue J, Yang J, Liu X, Chen H, Dean DB, Zhang C. 2007. MicroRNAs are aberrantly expressed in hypertrophic heart: Do they play a role in cardiac hypertrophy? Am J Pathol 170: 1831-1840.
9. Chiba Y, Misawa M. 2010. MicroRNAs and their therapeutic potential for human diseases: MiR-133a and bronchial smooth muscle hyperresponsiveness in asthma. J Pharmacol Sci 114: 264-268.
10. Cordes KR, Sheehy NT, White MP, Berry EC, Morton SU, Muth AN, Lee TH, Miano JM, Ivey KN, Srivastava D. 2009. miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature 460: 705-710.
11. Daubman S. 2010. MicroRNAs in angiogenesis and vascular smooth muscle cell function. Circ Res 106: 423-425.
12. Davis BN, Hilyard AC, Lagna G, Hata A. 2008. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 454: 56-61.
13. Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH. 2008. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 283: 1026-1033.
14. Fujita S, Ito T, Mizutani T, Minoguchi S, Yamamichi N, Sakurai K, Iba H. 2008. miR-21 gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J Mol Biol 378: 492-504.
15. Hoofnagle MH, Thomas JA, Wamhoff BR, Owens GK. 2006. Origin of neointimal smooth muscle: We've come full circle. Arterioscler Thromb Vasc Biol 26: 2579-2581.
16. Ishii I, Akahoshi N, Yu XN, Kobayashi Y, Namekata K, Komaki G, Kimura H. 2004. Murine cystathionine gamma-lyase: Complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression. Biochem J 381: 113-123.
17. Ji R, Cheng Y, Yue J, Yang J, Liu X, Chen H, Dean DB, Zhang C. 2007. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of microRNA in vascular neointimal lesion formation. Circ Res 100: 1579-1588.
18. Leeper NJ, Raiesdana A, Kojima Y, Chun HJ, Azuma J, Maegdefessel L, Kundu RK, Quertermous T, Tsao PS, Spin JM. 2011. MicroRNA-26a is a novel regulator of vascular smooth muscle cell function. J Cell Physiol 226: 1035-1043.
19. Lu Z, Liu M, Stribinskis V, Klinge CM, Ramos KS, Colburn NH, Li Y. 2008. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 27: 4373-4379.
20. Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. 2007a. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658.
21. Meng QH, Yang G, Yang W, Jiang B, Wu L, Wang R. 2007b. Protective effect of hydrogen sulfide on balloon injury-induced neointima hyperplasia in rat carotid arteries. Am J Pathol 170: 1406-1414.
22. Naraba H, Iwai N. 2005. Assessment of the microRNA system in salt-sensitive hypertension. Hypertens Res 28: 819-826.
23. Ohtani K, Dimmeler S. 2011. Control of cardiovascular differentiation by microRNAs. Basic Res Cardiol 106: 5-11.
24. Owens GK, Kumar MS, Wamhoff BR. 2004. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84: 767-801.
25. Pauly RR, Passaniti A, Bilato C, Monticone R, Cheng L, Papadopoulos N, Gluzband YA, Smith L, Weinstein C, Lakatta EG. 1994. Migration of cultured vascular smooth muscle cells through a basement membrane barrier requires type IV collagenase activity and is inhibited by cellular differentiation. Circ Res 75: 41-54.
26. Scalbert E, Bril A. 2008. Implication of microRNAs in the cardiovascular system. Curr Opin Pharmacol 8: 181-188.
27. Schramedei K, Mörbt N, Pfeifer G, Läuter J, Rosolowski M, Tomm JM, von Bergen M, Horn F, Brocke-Heidrich K. 2011. MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4. Oncogene 30: 2975-2985.
28. Sethupathy P, Megraw M, Hatzigeorgiou AG. 2006. A guide through present computational approaches for the identification of mammalian microRNA targets. Nat Methods 3: 881-886.
29. Song Z, Li G. 2010. Role of specific microRNAs in regulation of vascular smooth muscle cell differentiation and the response to injury. J Cardiovasc Transl Res 3: 246-250.
30. Stark A, Brennecke J, Bushati N, Russell RB, Cohen SM. 2005. Animal microRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell 123: 1133-1146.
31. Sullivan CS, Ganem D. 2008. MicroRNAs and viral infection. Mol Cell 20: 3-7.
32. Tatsuguchi M, Seok HY, Callis TE, Thomson JM, Chen JF, Newman M, Rojas M, Hammond SM, Wang DZ. 2007. Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J Mol Cell Cardiol 42: 1137-1141.
33. Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, Doevendans PA, Mummery CL, Borlak J, Haverich A, Gross C, Engelhardt S, Ertl G, Bauersachs J. 2007. MicroRNAs in the human heart: A clue to fetal gene reprogramming in heart failure. Circulation 116: 258-267.
34. Wang R. 2011. Signaling pathways for the vascular effects of hydrogen sulfide. Curr Opin Nephrol Hypertens 20: 107-112.
35. Xiao J, Yang B, Lin H, Lu Y, Luo X, Wang Z. 2007. Novel approaches for gene-specific interference via manipulating actions of microRNAs: Examination on the pacemaker channel genes HCN2 and HCN4. J Cell Physiol 212: 285-292.
36. Yang G, Pei Y, Teng H, Cao Q, Wang R. 2011. Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase expression during smooth muscle cell differentiation. J Biol Chem In press
37. Yang G, Sun X, Wang R. 2004. Hydrogen sulfide-induced apoptosis of human aorta smooth muscle cells via the activation of mitogen-activated protein kinases and caspase-3. FASEB J 18: 1782-1784.
38. Yang G, Wu L, Bryan S, Khaper N, Mani S, Wang R. 2010. Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells. Cardiovasc Res 86: 487-495.
39. 2S as a physiologic vasorelaxant: Hypertension in mice with deletion of cystathionine gamma-lyase. Science 322: 587-590.
40. Yang G. Hydrogen sulfide in cell survival: A double-edged sword. Expert Rev Clin Pharmacol 2011. 4: 33-47.
41. Yang Y, Chaerkady R, Beer MA, Mendell JT, Pandey A. 2009. Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach. Proteomics 9: 1374-1384.
42. Yao Q, Xu H, Zhang QQ, Zhou H, Qu LH. 2009. MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells. Biochem Biophys Res Commun 388: 539-542.
43. ATP channel opener. EMBO J 20: 6008-6016.
44. Zhu S, Si ML, Wu H, Mo YY. 2007. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 282: 14328-14336.
45. Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY. 2008. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 18: 350-359.