Simvastatin inhibits the additive activation of ERK1/2 and proliferation of rat vascular smooth muscle cells induced by combined mechanical stress and oxLDL through LOX-1 pathway

Cellular Signalling

Volumn 25, Issue 1, 2013, Pages 332-340

  Zhang, Zhengyu ^a,b   Zhang, Min ^a   Li, Yuhuang ^a   Liu, Shuying ^a   Ping, Suning ^a   Wang, Jingjing ^a   Ning, Fen ^a   Xie, Fukang ^a   Li, Chaohong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Atherosclerosis; LOX 1; OxLDL; Simvastatin; Stretch stress

Indexed keywords

KI 67 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; SIMVASTATIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; MECHANICAL STRESS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CELL PROLIFERATION; CELLS, CULTURED; ENZYME ACTIVATION; KI-67 ANTIGEN; LIPOPROTEINS, LDL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; RNA, SMALL INTERFERING; SCAVENGER RECEPTORS, CLASS E; SIGNAL TRANSDUCTION; SIMVASTATIN; STRESS, MECHANICAL; UP-REGULATION;

RATTUS;

EID: 84869887386     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.10.006     Document Type: Article

References (47)

1. Parang P., Arora R. The Canadian Journal of Cardiology 2009, 25:e57-62.
2. Goldman S., Zadina K., Moritz T., Ovitt T., Sethi G., Copeland J.G., Thottapurathu L., Krasnicka B., Ellis N., Anderson R.J., Henderson W. Journal of the American College of Cardiology 2004, 44:2149-2156.
3. Sabik J.F., Lytle B.W., Blackstone E.H., Houghtaling P.L., Cosgrove D.M. The Annals of Thoracic Surgery 2005, 79:544-551. (discussion 544-551).
4. Dietrich H., Hu Y., Zou Y., Huemer U., Metzler B., Li C., Mayr M., Xu Q. The American Journal of Pathology 2000, 157:659-669.
5. Lombard J.H., Eskinder H., Kauser K., Osborn J.L., Harder D.R. The American Journal of Physiology 1990, 259:H29-33.
6. Dobrin P.B. Hypertension 1995, 26:38-43.
7. Prado C.M., Ramos S.G., Alves-Filho J.C., Elias J., Cunha F.Q., Rossi M.A. Journal of Hypertension 2006, 24:503-515.
8. Loop F.D., Lytle B.W., Cosgrove D.M., Stewart R.W., Goormastic M., Williams G.W., Golding L.A., Gill C.C., Taylor P.C., Sheldon W.C., et al. The New England Journal of Medicine 1986, 314:1-6.
9. Li C., Xu Q. Cellular Signalling 2000, 12:435-445.
10. Chakravarthi S., Jessop C.E., Willer M., Stirling C.J., Bulleid N.J. The Biochemical Journal 2007, 404:403-411.
11. Hu Y., Bock G., Wick G., Xu Q. The FASEB Journal 1998, 12:1135-1142.
12. Li C., Xu Q. Cellular Signalling 2007, 19:881-891.
13. Chahine M.N., Blackwood D.P., Dibrov E., Richard M.N., Pierce G.N. Journal of Molecular and Cellular Cardiology 2009, 46:431-441.
14. Tanigawa H., Miura S., Zhang B., Uehara Y., Matsuo Y., Fujino M., Sawamura T., Saku K. Atherosclerosis 2006, 188:245-250.
15. Mitra S., Goyal T., Mehta J.L. Cardiovascular Drugs and Therapy 2011, 25:419-429.
16. Li C., Hu Y., Mayr M., Xu Q. The Journal of Biological Chemistry 1999, 274:25273-25280.
17. Li Y., Liu S., Zhang Z., Xu Q., Xie F., Wang J., Ping S., Li C., Wang Z., Zhang M., Huang J., Chen D., Hu L. PLoS One 2012, 7:e35016.
18. Maziere C., Trecherel E., Ausseil J., Louandre C., Maziere J.C. Atherosclerosis 2011, 218:308-313.
19. Metzler B., Li C., Hu Y., Sturm G., Ghaffari-Tabrizi N., Xu Q. Arteriosclerosis, Thrombosis, and Vascular Biology 1999, 19:1862-1871.
20. Velarde V., Jenkins A.J., Christopher J., Lyons T.J., Jaffa A.A. Journal of Applied Physiology 2001, 91:1412-1420.
21. Kulik A., Ruel M. Current Opinion in Cardiology 2011, 26:508-517.
22. Margaritis M., Channon K.M., Antoniades C. Current Opinion in Pharmacology 2012, 12:172-180.
23. Mayr U., Mayr M., Li C., Wernig F., Dietrich H., Hu Y., Xu Q. Circulation Research 2002, 90:197-204.
24. Banes A.J., Gilbert J., Taylor D., Monbureau O. Journal of Cell Science 1985, 75:35-42.
25. Hinagata J., Kakutani M., Fujii T., Naruko T., Inoue N., Fujita Y., Mehta J.L., Ueda M., Sawamura T. Cardiovascular Research 2006, 69:263-271.
26. Itabe H. Biological & Pharmaceutical Bulletin 2003, 26:1-9.
27. Lu J., Mitra S., Wang X., Khaidakov M., Mehta J.L. Antioxidants & Redox Signaling 2011, 15:2301-2333.
28. Nowicki M., Muller K., Serke H., Kosacka J., Vilser C., Ricken A., Spanel-Borowski K. Journal of Neuroscience Research 2010, 88:403-412.
29. Luo P., Yan M., Frohlich E.D., Mehta J.L., Hu C. Cardiovascular Drugs and Therapy 2011, 25:441-449.
30. Liang M., Zhang P., Fu J. Cancer Letters 2007, 258:31-37.
31. Eto H., Miyata M., Kume N., Minami M., Itabe H., Orihara K., Hamasaki S., Biro S., Otsuji Y., Kita T., Tei C. Biochemical and Biophysical Research Communications 2006, 341:591-598.
32. Tan K.C., Shiu S.W., Wong Y., Leng L., Bucala R. Journal of Lipid Research 2008, 49:1438-1444.
33. Sankaralingam S., Xu Y., Sawamura T., Davidge S.T. Hypertension 2009, 53:270-277.
34. Ge J., Huang D., Liang C., Luo Y., Jia Q., Wang K. Atherosclerosis 2004, 177:263-268.
35. Jono T., Miyazaki A., Nagai R., Sawamura T., Kitamura T., Horiuchi S. FEBS Letters 2002, 511:170-174.
36. Li D.Y., Zhang Y.C., Philips M.I., Sawamura T., Mehta J.L. Circulation Research 1999, 84:1043-1049.
37. Murase T., Kume N., Korenaga R., Ando J., Sawamura T., Masaki T., Kita T. Circulation Research 1998, 83:328-333.
38. Mehta J.L., Li D.Y. Biochemical and Biophysical Research Communications 1998, 248:511-514.
39. Yoshimoto R., Fujita Y., Kakino A., Iwamoto S., Takaya T., Sawamura T. Cardiovascular Drugs and Therapy 2011, 25:379-391.
40. Mehta J.L., Hu B., Chen J., Li D. Arteriosclerosis, Thrombosis, and Vascular Biology 2003, 23:2203-2208.
41. Mehta J.L., Chen J., Yu F., Li D.Y. Cardiovascular Research 2004, 64:243-249.
42. Chen J., Li D., Schaefer R., Mehta J.L. Atherosclerosis 2006, 184:295-301.
43. Hofnagel O., Luechtenborg B., Eschert H., Weissen-Plenz G., Severs N.J., Robenek H. Arteriosclerosis, Thrombosis, and Vascular Biology 2006, 26:604-610.
44. Takayama M., Matsubara M., Arakawa E., Takada C., Ina Y., Hasegawa K., Yao K. Vascular Pharmacology 2007, 46:302-308.
45. Domanski M., Tian X., Fleg J., Coady S., Gosen C., Kirby R., Sachdev V., Knatterud G., Braunwald E. The American Journal of Cardiology 2008, 102:1023-1027.
46. Antoniades C., Bakogiannis C., Tousoulis D., Reilly S., Zhang M.H., Paschalis A., Antonopoulos A.S., Demosthenous M., Miliou A., Psarros C., Marinou K., Sfyras N., Economopoulos G., Casadei B., Channon K.M., Stefanadis C. Circulation 2010, 122:S66-73.
47. Kozai T., Eto M., Yang Z., Shimokawa H., Luscher T.F. Cardiovascular Research 2005, 68:475-482.