Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice

Toxicology and Applied Pharmacology

Volumn 273, Issue 1, 2013, Pages 68-76

  Xu, Xiaomei ^a   Hu, Yan ^a   Zhai, Xiaohan ^a   Lin, Musen ^a   Chen, Zhao ^a   Tian, Xiaofeng ^a   Zhang, Feng ^a   Gao, Dongyan ^a   Ma, Xiaochi ^a   Lv, Li ^a   Yao, Jihong ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Concanavalin A; Hepatitis; Salvianolic acid A; SIRT1

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CONCANAVALIN A; LIVER PROTECTIVE AGENT; MESSENGER RNA; PROTEIN BCL XL; PROTEIN P66; SALVIANOLIC ACID A; SIRTUIN 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN HEPG2; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); DOWN REGULATION; GENE REPRESSION; GENETIC TRANSFECTION; HISTOPATHOLOGY; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

AIH; ALANINE AMINOTRANSFERASE; ALT; ASPARTATE AMINOTRANSFERASE; AST; AUTOIMMUNE HEPATITIS; B-CELL LYMPHOMA-EXTRA LARGE; BCL-XL; CONA; CONCANAVALIN A; HEPATITIS; IFN-Γ; INTERFERON GAMMA; NF-ΚB; NUCLEAR FACTOR ΚB; P66SHC; SALA; SALVIANOLIC ACID A; SIRT1; SIRTUIN1; THE 66KDA ISOFORM OF THE GROWTH FACTOR ADAPTER SHC; TNF-Α; TUMOR NECROSIS FACTOR-Α;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; BCL-X PROTEIN; CAFFEIC ACIDS; CASPASE 3; CONCANAVALIN A; DOWN-REGULATION; DRUG-INDUCED LIVER INJURY; EPIGENETIC REPRESSION; HEP G2 CELLS; HEPATITIS; HUMANS; INTERFERON-GAMMA; LACTATES; LIVER; MALE; MICE; NF-KAPPA B; RNA, MESSENGER; RNA, SMALL INTERFERING; SHC SIGNALING ADAPTOR PROTEINS; SIRTUIN 1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84884722053     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.08.021     Document Type: Article

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