Upregulation of Sirt1 in carbon-tetrachloride induced acute liver injury

Drug and Chemical Toxicology

Volumn 36, Issue 3, 2013, Pages 277-283

  Xie, Jun ^a   Wan, Jingyuan ^a   Jiang, Rong ^a   Lu, Hongxu ^a   Peng, Xiaorong ^a   Zhang, Li ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Acute liver injury; Carbon tetrachloride; Nicotinamide; Sirtuin 1

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; INTERLEUKIN 6; MESSENGER RNA; MYELOPEROXIDASE; NICOTINAMIDE; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL INFILTRATION; CYTOKINE PRODUCTION; DISEASE EXACERBATION; ENZYME ACTIVITY; ENZYME INDUCTION; LEUKOCYTE; LIVER; LIVER CELL DAMAGE; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BLOTTING, WESTERN; CARBON TETRACHLORIDE; CYTOKINES; DRUG-INDUCED LIVER INJURY; HEPATOCYTES; INTERLEUKIN-6; LEUKOCYTES; LIVER; MALE; MICE; MICE, INBRED BALB C; NIACINAMIDE; PEROXIDASE; REAL-TIME POLYMERASE CHAIN REACTION; SIRTUIN 1; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

MUS;

EID: 84871256121     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480545.2012.710630     Document Type: Article

References (37)

1. Alcendor, R. R., Gao, S., Zhai, P., Zablocki, D., Holle, E., Yu, X., et al. (2007). Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 100:1512-1521
2. Avalos, J. L., Bever, K. M., Wolberger, C. (2005). Mechanism of sirtuin inhibition by nicotinamide: Altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Mol Cell 17:855-868
3. Bitterman, K. J., Anderson, R. M., Cohen, H. Y., Latorre-Esteves, M., Sinclair, D. A. (2002). Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J Biol Chem 277:45099-45107
4. Chen, J, Zhou, Y, Mueller-Steiner, S, Chen, LF, Kwon, H, Yi, S, et al. (2005). SIRT1 protects against microglia-dependent amyloidbeta toxicity through inhibiting NF-kappaB signaling. J Biol Chem 280:40364-40374
5. Chung, S., Yao, H., Caito, S., Hwang, J. W., Arunachalam, G., Rahman, I. (2010). Regulation of SIRT1 in cellular functions: Role of polyphenols. Arch Biochem Biophys 501:79-90
6. Colak, Y, Ozturk, O, Senates, E, Tuncer, I, Yorulmaz, E, Adali, G, et al. (2011). SIRT1 as a potential therapeutic target for treatment of nonalcoholic fatty liver disease. Med Sci Monit 17:HY5-HY9
7. Csiszar, A, Labinskyy, N, Podlutsky, A, Kaminski, PM, Wolin, MS, Zhang, C, et al. (2008). Vasoprotective effects of resveratrol and SIRT1: Attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol 294:H2721-H2735
8. Czaja, M. J., Xu, J., Alt, E. (1995). Prevention of carbon tetrachlorideinduced rat liver injury by soluble tumor necrosis factor receptor. Gastroenterology 108:1849-1854
9. das Neves, R. N., Carvalho, F., Carvalho, M., Fernandes, E., Soares, E., de Bastos, M. L., et al. (2004). Protective activity of hesperidin and lipoic acid against sodium arsenite acute toxicity in mice. Toxicol Pathol 32:527-535
10. Donmez, G., Guarente, L. (2010). Aging and disease: Connections to sirtuins. Aging Cell 9:285-290
11. Erion, DM, Yonemitsu, S, Nie, Y, Nagai, Y, Gillum, MP, Hsiao, JJ, et al. (2009). SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats. Proc Natl Acad Sci U S A 106:11288-11293
12. Furukawa, A., Tada-Oikawa, S., Kawanishi, S., Oikawa, S. (2007). H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion. Cell Physiol Biochem 20:45-54
13. Hammes, T. O., Pedroso, G. L., Hartmann, C. R., Escobar, T. D., Fracasso, L. B., da Rosa, D. P., et al. (2012). The effect of taurine on hepatic steatosis induced by thioacetamide in zebrafish (Danio rerio). Dig Dis Sci 57:675-682
14. Hasegawa, K., Wakino, S., Yoshioka, K., Tatematsu, S., Hara, Y., Minakuchi, H., et al. (2008). Sirt1 protects against oxidative stressinduced renal tubular cell apoptosis by the bidirectional regulation of catalase expression. Biochem Biophys Res Commun 72:51-56
15. Immenschuh, S., Baumgart-Vogt, E., Mueller, S. (2010). Heme oxygenase-1 and iron in liver inflammation: A complex alliance. Curr Drug Targets 11:1541-1550
16. Jackson, M. D., Schmidt, M. T., Oppenheimer, N. J., Denu, J. M. (2003). Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases. J Biol Chem 278:50985-50998
17. Kondo, T., Suda, T., Fukuyama, H., Adachi, M., Nagata, S. (1997). Essential roles of the Fas ligand in the development of hepatitis. Nat Med 3:409-413
18. Ling, P. R., Smith, R. J., Kie, S., Boyce, P., Bistrian, B. R. (2004). Effects of protein malnutrition on IL-6-mediated signaling in the liver and the systemic acute-phase response in rats. Am J Physiol Regul Integr Comp Physiol 287:R801-R808
19. Malhi, H., Gores, G. J. (2008). Cellular and molecular mechanisms of liver injury. Gastroenterology 134:1641-1654
20. Ohta, Y., Imai, Y., Matsura, T., Kitagawa, A., Yamada, K. (2006). Preventive effect of neutropenia on carbon tetrachloride-induced hepatotoxicity in rats. J Appl Toxicol 26:178-186
21. Pfluger, P. T., Herranz, D., Velasco-Miguel, S., Serrano, M., Tschop, M. H. (2008). Sirt1 protects against high-fat diet-induced metabolic damage. Proc Natl Acad Sci U S A 105:9793-9798
22. Purushotham, A., Schug, T. T., Xu, Q., Surapureddi, S., Guo, X., Li, X. (2009). Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab 9:327-338
23. Purushotham, A., Xu, Q., Lu, J., Foley, J. F., Yan, X., Kim, D. H., et al. (2012). Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice. Mol Cell Biol 32:1226-1236
24. Rajendrasozhan, S., Yang, S. R., Kinnula, V. L., Rahman, I. (2008). SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 177:861-870
25. Schug, T. T., Li, X. (2011). Sirtuin 1 in lipid metabolism and obesity. Ann Med 43:198-211
26. Schug, T. T., Xu, Q., Gao, H., Peres-da-Silva, A., Draper, D. W., Fessler, M. B., et al. (2010). Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress. Mol Cell Biol 30:4712-4721
27. Shen, Z., Ajmo, J. M., Rogers, C. Q., Liang, X., Le, L., Murr, M. M., et al. (2009). Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-alpha production in cultured macrophage cell lines. Am J Physiol Gastrointest Liver Physiol 296:G1047-G1053
28. Smith, B. C., Hallows, W. C., Denu, J. M. (2008). Mechanisms and molecular probes of sirtuins. Chem Biol 15:1002-1013
29. Sprague, C. L., Elfarra, A. A. (2005). Protection of rats against 3-butene- 1,2-diol-induced hepatotoxicity and hypoglycemia by N-acetyl-lcysteine. Toxicol Appl Pharmacol 207:266-274
30. Taniguchi, M., Takeuchi, T., Nakatsuka, R., Watanabe, T., Sato, K. (2004). Molecular process in acute liver injury and regeneration induced by carbon tetrachloride. Life Sci 75:1539-1549
31. Wang, R. H., Kim, H. S., Xiao, C., Xu, X., Gavrilova, O., Deng, C. X. (2011). Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance. J Clin Invest 121:4477-4490
32. Weber, L. W., Boll, M., Stampfl, A. (2003). Hepatotoxicity and mechanism of action of haloalkanes: Carbon tetrachloride as a toxicological model. Crit Rev Toxicol 33:105-136
33. Yeung, F., Hoberg, J. E., Ramsey, C. S., Keller, M. D., Jones, D. R., Frye, R. A., et al. (2004). Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 23:2369-2380
34. Zhang, R., Chen, H. Z., Liu, J. J., Jia, Y. Y., Zhang, Z. Q., Yang, R. F., et al. (2010a). SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages. J Biol Chem 285:7097-7110
35. Zhang, J., Lee, S. M., Shannon, S., Gao, B., Chen, W., Chen, A., et al. (2009). The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice. J Clin Invest 119:3048-3058
36. Zhang, H. N., Li, L., Gao, P., Chen, H. Z., Zhang, R., Wei, Y. S., et al. (2010b). Involvement of the p65/RelA subunit of NF-kappaB in TNF-alpha-induced SIRT1 expression in vascular smooth muscle cells. Biochem Biophys Res Commun 397:569-575
37. Zhang, L., Wan, J., Li, H., Wu, P., Jin, S., Zhou, X., et al. (2007). Protective effects of BML-111, a lipoxin A(4) receptor agonist, on carbon tetrachloride-induced liver injury in mice. Hepatol Res 37:948-956