Effects of resveratrol on H2O2-induced apoptosis and expression of SIRTs in H9c2 cells

Journal of Cellular Biochemistry

Volumn 107, Issue 4, 2009, Pages 741-747

  Yu, Wei ^a   Fu, Yu Cai ^a   Zhou, Xiao Hui ^a   Chen, Chun Juan ^a   Wang, Xin ^a   Lin, Rui Bo ^a   Wang, Wei ^a  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

Cardiomyocyte apoptosis caspase 3; Oxidative stress; Resveratrol; SIRTs

Indexed keywords

CASPASE 3; HYDROGEN PEROXIDE; NICOTINAMIDE; RESVERATROL; SIRTUIN 1; SIRTUIN 3; SIRTUIN 4; SIRTUIN 7;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; HEART MUSCLE CELL; HEART PROTECTION; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE; GENE EXPRESSION REGULATION; HYDROGEN PEROXIDE; MYOCYTES, CARDIAC; RATS; SIRTUINS; STILBENES;

EID: 67650070375     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22169     Document Type: Article

References (27)

1. Alcendor RR, Kirshenbaum LA, Imai S, Vatner SF, Sadoshima J. 2004. Silent information regulator 2α, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. Circ Res 95:971-980. (Pubitemid 39532327)
2. Alcendor RR, Gao S, Zhai P, Zablocki D, Holle E, Yu X, Tian B, Wagner T, Vatner SF, Sadoshima J. 2007. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 100:1512-1521. (Pubitemid 46834764)
3. Borra MT, Smith BC, Denu JM. 2005. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem 280:17187-17195. (Pubitemid 41389185)
4. Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, Hu LS, Cheng HL, Jedrychowski MP, Gygi SP, Sinclair DA, Alt FW, Greenberg ME. 2004. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303:2011-2015. (Pubitemid 38393275)
5. Cao C, Lu S, Kivlin R, Wallin B, Card E, Bagdasarian A, Tamakloe T, Wang WJ, Song X, Chu WM, Kouttab N, Xu A, Wan Y. 2008. SIRT1 confers protection against UVB- and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes. J Cell Mol Med DOI: 10.1111/j.1582-4934.2008.00453. x.
6. Chen CJ, Yu W, Fu YC, Wang X, Li JL, Wang W. 2009. Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway. Biochem Biophys Res Commun 378:389-393.
7. Crow MT, Mani K, Nam YJ, Kitsis RN. 2004. The mitochondrial death pathway and cardiac myocyte apoptosis. Circ Res 95:957-970. (Pubitemid 39532326)
8. Fridovich I. 1997. Superoxide anion radical (O2-.), superoxide dismutases, and related matters. J Biol Chem 272:18515-18517.
9. Frye RA. 1999. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem Biophys Res Commun 260:273-279. (Pubitemid 29351819)
10. Frye RA. 2000. Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 273:793-798. (Pubitemid 30599063)
11. Fulco M, Schiltz RL, Iezzi S, King MT, Zhao P, Kashiwaya Y, Hoffman E, Veech RL, Sartorelli V. 2003. Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol Cell 12:51-62. (Pubitemid 36945036)
12. Haigis MC, Guarente LP. 2006. Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. Genes Dev 20:2913-2921. (Pubitemid 44771725)
13. Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA. 2003. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425:191-196. (Pubitemid 37150899)
14. Imai S, Armstrong CM, Kaeberlein M, Guarente L. 2000. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403:795-800. (Pubitemid 30111843)
15. Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W. 2001. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107:137-148. (Pubitemid 33035941)
16. Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, Bultsma Y, McBurney M, Guarente L. 2004. Mammalian SIRT1 represses forkhead transcription factors. Cell 116:551-563. (Pubitemid 38264432)
17. Murdoch CE, Zhang M, Cave AC, Shah AM. 2006. NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure. Cardiovasc Res 71:208-215. (Pubitemid 43913729)
18. Pervaiz S. 2003. Resveratrol: From grapevines to mammalian biology. FASEB J 17:1975-1985.
19. Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. 2005. Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1. Nature 434:113-118. (Pubitemid 40349395)
20. Smith JS, Brachmann CB, Celic I, Kenna MA, Muhammad S, Starai VJ, Avalos JL, Escalante-Semerena JC, Grubmeyer C, Wolberger C, Boeke JD. 2000. A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci USA 97:6658-6663. (Pubitemid 30412770)
21. Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB, Gupta MP. 2008. SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 28:6384-6401.
22. Turner NA, Xia F, Azhar G, Zhang X, Liu L, Wei JY. 1998. Oxidative stress induces DNA fragmentation and caspase activation via the c-Jun NH2-terminal kinase pathway in H9c2 cardiac muscle cells. J Mol Cell Cardiol 30:1789-1801. (Pubitemid 28430193)
23. Vakhrusheva O, Smolka C, Gajawada P, Kostin S, Boettger T, Kubin T, Braun T, Bober E. 2008. Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice. Circ Res 102:703-710.
24. Westerheide SD, Anckar J, Stevens SM, Jr., Sistonen L, Morimoto RI. 2009. Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science 323:1063-1066.
25. Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D. 2004. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430:686-689. (Pubitemid 39061685)
26. Yamamoto H, Schoonjans K, Auwerx J. 2007. Sirtuin functions in health and disease. Mol Endocrinol 21:1745-1755.
27. Yoshida Y, Shioi T, Izumi T. 2007. Resveratrol ameliorates experimental autoimmune myocarditis. Circulation 71:397-404. (Pubitemid 46409545)