-
1
-
-
77549084735
-
Abnormal calcium homeostasis in peripheral neuropathies
-
Fernyhough, P.; Calcutt, N.A. Abnormal calcium homeostasis in peripheral neuropathies. Cell Calcium. 2010, 47, 130-139.
-
(2010)
Cell Calcium.
, vol.47
, pp. 130-139
-
-
Fernyhough, P.1
Calcutt, N.A.2
-
2
-
-
78651101592
-
Diabetic neuropathies: Update on definitions, diagnostic criteria, estimation of severity, and treatments
-
Tesfaye, S.; Boulton, A.J.; Dyck, P.J.; Freeman, R.; Horowitz, M.; Kempler, P.; Lauria, G.; Malik, R.A.; Spallone, V.; Vinik, A.; et al. Diabetic neuropathies: Update on definitions, diagnostic criteria, estimation of severity, and treatments. Diabetes Care 2010, 33, 2285-2293.
-
(2010)
Diabetes Care
, vol.33
, pp. 2285-2293
-
-
Tesfaye, S.1
Boulton, A.J.2
Dyck, P.J.3
Freeman, R.4
Horowitz, M.5
Kempler, P.6
Lauria, G.7
Malik, R.A.8
Spallone, V.9
Vinik, A.10
-
3
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee, M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414, 813-820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
4
-
-
58249098507
-
A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress
-
Huang, Q.; Wu, Y.T.; Tan, H.L.; Ong, C.N.; Shen, H.M. A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress. Cell Death Differ. 2009, 16, 264-277.
-
(2009)
Cell Death Differ.
, vol.16
, pp. 264-277
-
-
Huang, Q.1
Wu, Y.T.2
Tan, H.L.3
Ong, C.N.4
Shen, H.M.5
-
5
-
-
64349115078
-
AMPK in the brain: Its roles in energy balance and neuroprotection
-
Ronnett, G.V.; Ramamurthy, S.; Kleman, A.M.; Landree, L.E.; Aja, S. AMPK in the brain: Its roles in energy balance and neuroprotection. J. Neurochem. 2009, 109, 17-23.
-
(2009)
J. Neurochem.
, vol.109
, pp. 17-23
-
-
Ronnett, G.V.1
Ramamurthy, S.2
Kleman, A.M.3
Landree, L.E.4
Aja, S.5
-
6
-
-
70349324339
-
Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthasekinase-3β inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway
-
Shin, S.M.; Cho, I.J.; Kim, S.G. Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthasekinase-3β inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway. Mol. Pharmacol. 2009, 76, 884-895.
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 884-895
-
-
Shin, S.M.1
Cho, I.J.2
Kim, S.G.3
-
7
-
-
80053174960
-
Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain
-
doi:10.1186/1744-8069-7-70
-
Melemedjian, O.K.; Asiedu, M.N.; Tillu, D.V.; Sanoja, R.; Yan, J.; Lark, A.; Khoutorsky, A.; Johnson, J.; Peebles, K.A.; Lepow, T.; et al. Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain. Mol. Pain 2011, 7, doi:10.1186/1744-8069-7-70.
-
(2011)
Mol. Pain
, pp. 7
-
-
Melemedjian, O.K.1
Asiedu, M.N.2
Tillu, D.V.3
Sanoja, R.4
Yan, J.5
Lark, A.6
Khoutorsky, A.7
Johnson, J.8
Peebles, K.A.9
Lepow, T.10
-
8
-
-
82755197943
-
Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes
-
Chowdhury, S.R.; Dobrowsky, R.T.; Fernyhough, P. Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes. Mitochondrion 2011, 11, 845-854.
-
(2011)
Mitochondrion
, vol.11
, pp. 845-854
-
-
Chowdhury, S.R.1
Dobrowsky, R.T.2
Fernyhough, P.3
-
9
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
Hirschey, M.D.; Shimazu, T.; Goetzman, E.; Jing, E.; Schwer, B.; Lombard, D.B.; Grueter, C.A.; Harris, C.; Biddinger, S.; Ilkayeva, O.R.; et al. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 2010, 464, 121-125.
-
(2010)
Nature
, vol.464
, pp. 121-125
-
-
Hirschey, M.D.1
Shimazu, T.2
Goetzman, E.3
Jing, E.4
Schwer, B.5
Lombard, D.B.6
Grueter, C.A.7
Harris, C.8
Biddinger, S.9
Ilkayeva, O.R.10
-
10
-
-
69249206539
-
A continuous microplate assay for sirtuins and nicotinamide-producing enzymes
-
Smith, B.C.; Hallows, W.C.; Denu, J.M. A continuous microplate assay for sirtuins and nicotinamide-producing enzymes. Anal. Biochem. 2009, 394, 101-109.
-
(2009)
Anal. Biochem.
, vol.394
, pp. 101-109
-
-
Smith, B.C.1
Hallows, W.C.2
Denu, J.M.3
-
11
-
-
34548079309
-
Cardiovascular effects of Danshen
-
Cheng, T.O. Cardiovascular effects of Danshen. Int. J. Cardiol. 2007, 121, 9-22.
-
(2007)
Int. J. Cardiol.
, vol.121
, pp. 9-22
-
-
Cheng, T.O.1
-
12
-
-
70249126166
-
Effect of salvianolic acid A on vascular reactivity of streptozotocin-induced diabetic rats
-
Wang, S.B.; Yang, X.Y.; Tian, S.; Yang, H.G.; Du, G.H. Effect of salvianolic acid A on vascular reactivity of streptozotocin-induced diabetic rats. Life Sci. 2009, 85, 499-504.
-
(2009)
Life Sci.
, vol.85
, pp. 499-504
-
-
Wang, S.B.1
Yang, X.Y.2
Tian, S.3
Yang, H.G.4
Du, G.H.5
-
13
-
-
79958270752
-
Effects of salvianolic scid A on plantar microcirculation and peripheral nerve function in diabetic rats
-
Yang, X.Y.; Sun, L.; Xu, P.; Gong, L.L.; Qiang, G.F.; Zhang, L.; Du, G.H. Effects of salvianolic scid A on plantar microcirculation and peripheral nerve function in diabetic rats. Eur. J. Pharmacol. 2011, 665, 40-46.
-
(2011)
Eur. J. Pharmacol.
, vol.665
, pp. 40-46
-
-
Yang, X.Y.1
Sun, L.2
Xu, P.3
Gong, L.L.4
Qiang, G.F.5
Zhang, L.6
Du, G.H.7
-
14
-
-
33644943620
-
AMPK: A key sensor of fuel and energy status in skeletal muscle
-
Hardie, D.G.; Sakamoto, K. AMPK: A key sensor of fuel and energy status in skeletal muscle. Physiology (Bethesda) 2006, 21, 48-60.
-
(2006)
Physiology (Bethesda)
, vol.21
, pp. 48-60
-
-
Hardie, D.G.1
Sakamoto, K.2
-
15
-
-
64449087671
-
Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio
-
Emerling, B.M.; Weinberg, F.; Snyder, C.; Burgess, Z.; Mutlu, G.M.; Viollet, B.; Budinger, G.R.S.; Chandel, N.S. Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radic. Biol. Med. 2009, 46, 1386-1391.
-
(2009)
Free Radic. Biol. Med.
, vol.46
, pp. 1386-1391
-
-
Emerling, B.M.1
Weinberg, F.2
Snyder, C.3
Burgess, Z.4
Mutlu, G.M.5
Viollet, B.6
Budinger, G.R.S.7
Chandel, N.S.8
-
16
-
-
75349099919
-
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
-
Fogarty, S.; Hardie, D.G. Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer. Biochim. Biophys. Acta 2010, 1804, 581-591.
-
(2010)
Biochim. Biophys. Acta
, vol.1804
, pp. 581-591
-
-
Fogarty, S.1
Hardie, D.G.2
-
17
-
-
77951250700
-
Oligomycin-induced bioenergetic adaptation in cancer cells with heterogeneous bioenergetic organization
-
Hao, W.S.; Chang, C.P.B.; Tsao, C.C.; Xu, J. Oligomycin-induced bioenergetic adaptation in cancer cells with heterogeneous bioenergetic organization. J. Biol. Chem. 2010, 285, 12647-12654.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 12647-12654
-
-
Hao, W.S.1
Chang, C.P.B.2
Tsao, C.C.3
Xu, J.4
-
18
-
-
26444608572
-
Structural basis for glycogen recognition by AMP-activated protein kinase
-
Polekhina, G.; Gupta, A.; van Denderen, B.J.; Feil, S.C.; Kemp, B.E.; Stapleton, D.; Parker, M.W. Structural basis for glycogen recognition by AMP-activated protein kinase. Structure 2005, 13, 1453-1462.
-
(2005)
Structure
, vol.13
, pp. 1453-1462
-
-
Polekhina, G.1
Gupta, A.2
Van Denderen, B.J.3
Feil, S.C.4
Kemp, B.E.5
Stapleton, D.6
Parker, M.W.7
-
19
-
-
79955776388
-
Salvianolic acids: Small compounds with multiple mechanisms for cardiovascular protection
-
Ho, J.H.C.; Hong, C.Y. Salvianolic acids: Small compounds with multiple mechanisms for cardiovascular protection. J. Biomed. Sci. 2011, 18, 1-5.
-
(2011)
J. Biomed. Sci.
, vol.18
, pp. 1-5
-
-
Ho, J.H.C.1
Hong, C.Y.2
-
20
-
-
65749095573
-
Natural product inhibitors of protein-protein interactions mediated by Src-family SH2 domains
-
Sperl, B.; Seifert, M.H.J.; Berg, T. Natural product inhibitors of protein-protein interactions mediated by Src-family SH2 domains. Bioorg. Med. Chem. Lett. 2009, 19, 3305-3309.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 3305-3309
-
-
Sperl, B.1
Seifert, M.H.J.2
Berg, T.3
-
21
-
-
67749111502
-
The LKB1-AMPK pathway: Metabolism and growth control in tumor suppression
-
Shackelford, D.B.; Shaw, R.J. The LKB1-AMPK pathway: Metabolism and growth control in tumor suppression. Nat. Rev. Cancer 2009, 9, 563-575.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
22
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
-
Handschin, J.S.; Pierre, C.S; Spiegelman, B.M. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc. Natl. Acad. Sci. USA 2007, 104, 12017-12022.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 12017-12022
-
-
Handschin, J.S.1
Pierre, C.S.2
Spiegelman, B.M.3
-
23
-
-
58149122724
-
Antioxidant regulatory mechanisms in neutrophils and lymphocytes after intense exercise
-
Ferrer, M.D.; Tauler, P.; Sureda, A.; Tur, J.A.; Pons, A. Antioxidant regulatory mechanisms in neutrophils and lymphocytes after intense exercise. J. Sports Sci. 2009, 27, 49-58.
-
(2009)
J. Sports Sci.
, vol.27
, pp. 49-58
-
-
Ferrer, M.D.1
Tauler, P.2
Sureda, A.3
Tur, J.A.4
Pons, A.5
-
24
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
Kim, D.; Nguyen, M.D.; Dobbin, M.M.; Fischer, A.; Sananbenesi, F.; Rodgers, J.T.; Delalle, I.; Baur, J.A.; Sui, G.; Armour, S.M.; et al. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J. 2007, 26, 3169-3179.
-
(2007)
EMBO J.
, vol.26
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
Fischer, A.4
Sananbenesi, F.5
Rodgers, J.T.6
Delalle, I.7
Baur, J.A.8
Sui, G.9
Armour, S.M.10
-
25
-
-
6044239444
-
Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle
-
Li, J.; Hu, X.Y.; Selvakumar, P.; Russell, R.R., 3rd.; Cushman, S.W.; Holman, G.D.; Young, L.H. Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle. Am. J. Physiol. Endocrinol. Metab. 2004, 287, E834-E841.
-
(2004)
Am. J. Physiol. Endocrinol. Metab.
, vol.287
-
-
Li, J.1
Hu, X.Y.2
Selvakumar, P.3
Russell Iii, R.R.4
Cushman, S.W.5
Holman, G.D.6
Young, L.H.7
-
26
-
-
0033667964
-
AMPK signaling in contracting human skeletal muscle: Acetyl-CoA carboxylase and NO synthase phosphorylation
-
Chen, Z.P.; McConell, G.K.; Michell, B.J.; Snow, R.J.; Canny, B.J.; Kemp, B.E. AMPK signaling in contracting human skeletal muscle: Acetyl-CoA carboxylase and NO synthase phosphorylation. Am. J. Physiol. Endocrinol. Metab. 2000, 279, E1202-E1206.
-
(2000)
Am. J. Physiol. Endocrinol. Metab.
, vol.279
-
-
Chen, Z.P.1
McConell, G.K.2
Michell, B.J.3
Snow, R.J.4
Canny, B.J.5
Kemp, B.E.6
-
27
-
-
78349246757
-
Sepiapterin reverses the changes in gastric nNOS dimerization and function in diabetic gastroparesis
-
Gangula, P.R.R.; Mukhopadhyay, S.; Pasricha, P.J.; Ravella, K. Sepiapterin reverses the changes in gastric nNOS dimerization and function in diabetic gastroparesis. Neurogastroenterol. Motil. 2010, 22, e1325-e1352.
-
(2010)
Neurogastroenterol. Motil.
, vol.22
-
-
Gangula, P.R.R.1
Mukhopadhyay, S.2
Pasricha, P.J.3
Ravella, K.4
-
28
-
-
67649415964
-
Peripheral neuropathy in mice with neuronal nitric oxide synthase gene deficiency
-
Vareniuk, I.; Pacher, P.; Pavlov, I.A.; Drel, V.R.; Obrosova, I.G. Peripheral neuropathy in mice with neuronal nitric oxide synthase gene deficiency. Int. J. Mol. Med. 2009, 23, 571-580.
-
(2009)
Int. J. Mol. Med.
, vol.23
, pp. 571-580
-
-
Vareniuk, I.1
Pacher, P.2
Pavlov, I.A.3
Drel, V.R.4
Obrosova, I.G.5
-
29
-
-
4143110556
-
Oxidative stress in the pathogenesis of diabetic neuropathy
-
Vincent, A.M.; Russell, J.W.; Low, P.; Feldman, E.L. Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr. Rev. 2004, 25, 612-628.
-
(2004)
Endocr. Rev.
, vol.25
, pp. 612-628
-
-
Vincent, A.M.1
Russell, J.W.2
Low, P.3
Feldman, E.L.4
-
30
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
Nishikawa, T.; Edelstein, D.; Du, X.L.; Yamagishi, S.; Matsumura, T.; Kaneda, Y.; Yorek, A.; Beebe, D.; Oates, P.J.; Hammes, H.P.; et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000, 404, 787-790.
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
Yamagishi, S.4
Matsumura, T.5
Kaneda, Y.6
Yorek, A.7
Beebe, D.8
Oates, P.J.9
Hammes, H.P.10
-
31
-
-
80053629798
-
Salvianolic acid A protects against vascular endothelial dysfunction in high-fat diet fed and streptozotocin-induced diabetic rats
-
Yang, X.Y.; Qiang, G.F.; Zhang, L.; Zhu, X.M.; Wang, S.B.; Sun, L.; Yang, H.G.; Du, G.H. Salvianolic acid A protects against vascular endothelial dysfunction in high-fat diet fed and streptozotocin-induced diabetic rats. J. Asian Nat. Prod. Res. 2011, 13, 884-894.
-
(2011)
J. Asian Nat. Prod. Res.
, vol.13
, pp. 884-894
-
-
Yang, X.Y.1
Qiang, G.F.2
Zhang, L.3
Zhu, X.M.4
Wang, S.B.5
Sun, L.6
Yang, H.G.7
Du, G.H.8
|