7α-Hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11β-hydroxysteroid dehydrogenase in EtC cerebellar neurons

Journal of Steroid Biochemistry and Molecular Biology

Volumn 138, Issue , 2013, Pages 290-297

  Gottfried Blackmore, Andres ^a   Jellinck, Peter H ^b   Vecchiarelli, Haley A ^a   Masheeb, Zahrah ^a   Kaufmann, Martin ^b   McEwen, Bruce S ^a   Bulloch, Karen ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

11 Hydroxysteroid dehydrogenase; Dehydroepiandrosterone; Glucocorticoids; Hexose 6 phosphate dehydrogenase; Neurosteroids

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTERONE; DEHYDROCORTICOSTERONE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; KETOCONAZOLE; PRASTERONE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CORTICOSTEROID METABOLISM; ENZYME ACTIVITY; HYDROXYLATION; MOUSE; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; WHOLE CELL;

11Β-HSD1 OR 2; 11Β-HYDROXYSTEROID DEHYDROGENASE; 11Β-HYDROXYSTEROID DEHYDROGENASE ISOFORM 1 OR 2; 11-DEHYDRO-CORT; 11-DEHYDROCORTICOSTERONE; 3Β-HYDROXY-5-ANDROSTENE-17-ONE (DEHYDROEPIANDROSTERONE); 7-HYDROXY-DEHYDROEPIANDROSTERONE; 7OH-DHEA; CORT; CORTICOSTERONE; DEHYDROEPIANDROSTERONE; DHEA; GLUCOCORTICOIDS; H6PDH; HEXOSE-6-PHOSPHATE DEHYDROGENASE; KC; KETOCONAZOLE; NEUROSTEROIDS;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; CELL LINE; CEREBELLUM; DEHYDROEPIANDROSTERONE; GLUCOCORTICOIDS; MICE; NEURONS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84884557271     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2013.07.001     Document Type: Article

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