7-Hydroxylated epiandrosterone (7-OH-EPIA) reduces ischaemia-induced neuronal damage both in vivo and in vitro

European Journal of Neuroscience

Volumn 18, Issue 1, 2003, Pages 117-124

  Pringle, Ashley K ^a   Schmidt, Werner ^b   Deans, Jackie K ^a   Wulfert, Ernst ^c   Reymann, Klaus G ^b,d   Sundstrom, Lars E ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b Research Institute for Applied Neuroscience (FAN gGmbH)   (Germany)

^c Hunter Fleming Ltd   (United Kingdom)

^d LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

Author keywords

Cerebral ischaemia; Hippocampus; Neuroprotection; Organotypic culture; Rat

Indexed keywords

7ALPHA HYDROXYEPIANDROSTERONE; 7BETA HYDROXYEPIANDROSTERONE; CYCTOCHROME P450 7B; CYTOCHROME P450 ISOENZYME; EPIANDROSTERONE; ESTRADIOL; PRASTERONE; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; BRAIN SLICE; CELL HYPOXIA; CELL LOSS; CONTROLLED STUDY; DEGENERATIVE DISEASE; FOREBRAIN; HIPPOCAMPUS; HORMONE ACTION; IN VITRO STUDY; IN VIVO STUDY; ISCHEMIA; MALE; NERVE CELL CULTURE; NERVE CELL LESION; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PYRAMIDAL NERVE CELL; RAT; STEROID HYDROXYLATION; STEROID METABOLISM;

ANIMALS; BRAIN ISCHEMIA; HYDROXYSTEROIDS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; ORGAN CULTURE TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR;

EID: 0042668350     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02734.x     Document Type: Article

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