Hexose-6-phosphate dehydrogenase modulates 11β-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7β-hydroxy-neurosteroids

PLoS ONE

Volumn 2, Issue 6, 2007, Pages

  Nashev, Lyubomir G ^a,b   Chandsawangbhuwana, Charlie ^c   Balazs, Zoltan ^a,b   Atanasov, Atanas G ^b   Dick, Bernhard ^b   Frey, Felix J ^b   Baker, Michael E ^c   Odermatt, Alex ^a,b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; 11BETA HYDROXYSTEROID DEHYDROGENASE 1; 7 KETODEHYDROEPIANDROSTERONE; 7 KETOPREGNENOLONE; 7ALPHA HYDROXYPRASTERONE; 7BETA HYDROXYPRASTERONE; 7BETA HYDROXYPREGNENOLONE; CORTISONE; GLUCOCORTICOID; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HYDROCORTISONE; NEUROSTEROID; PRASTERONE; PREGNENOLONE; UNCLASSIFIED DRUG; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; GALACTOSE 6 PHOSPHATE DEHYDROGENASE; GALACTOSE-6-PHOSPHATE DEHYDROGENASE; HSD11B1 PROTEIN, HUMAN; OXIDOREDUCTASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIGAND BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STEADY STATE; STEROID METABOLISM; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; ENZYME SPECIFICITY; KIDNEY; METABOLISM;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; CARBOHYDRATE DEHYDROGENASES; CELLS, CULTURED; CORTISONE; DEHYDROEPIANDROSTERONE; HUMANS; HYDROCORTISONE; KIDNEY; MODELS, MOLECULAR; NEUROTRANSMITTER AGENTS; SUBSTRATE SPECIFICITY;

EID: 39349102358     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000561     Document Type: Article

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