The Broken MLL Gene Is Frequently Located Outside the Inherent Chromosome Territory in Human Lymphoid Cells Treated with DNA Topoisomerase II Poison Etoposide

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Glukhov, Sergey I ^a   Rubtsov, Mikhail A ^a   Alexeyevsky, Daniil A ^a   Alexeevski, Andrei V ^a,d   Razin, Sergey V ^a,b,c   Iarovaia, Olga V ^b  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b INSTITUTE OF GENE BIOLOGY   (Russian Federation)

^c LIA 1066 French Russian Joint Cancer Research Laboratory   (Russian Federation)

^d RUSSIAN ACADEMY OF SCIENCES   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; MIXED LINEAGE LEUKEMIA PROTEIN;

ARTICLE; CHROMOSOME 11; CONTROLLED STUDY; DNA CLEAVAGE; DNA STRAND BREAKAGE; GENE LOCATION; GENE REARRANGEMENT; GENE SEQUENCE; HUMAN; HUMAN CELL; LYMPHOID CELL; MLL GENE;

CHROMOSOMES, HUMAN, PAIR 11; DNA CLEAVAGE; DNA TOPOISOMERASES, TYPE II; ETOPOSIDE; HUMANS; IMAGING, THREE-DIMENSIONAL; IN SITU HYBRIDIZATION, FLUORESCENCE; JURKAT CELLS; LYMPHOCYTES; MICROSCOPY, CONFOCAL; MODELS, MOLECULAR; MYELOID-LYMPHOID LEUKEMIA PROTEIN; TRANSLOCATION, GENETIC;

EID: 84884537085     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075871     Document Type: Article

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