Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 528-540

  Huang, Kaipeng ^a   Huang, Juan ^a   Xie, Xi ^a   Wang, Shaogui ^a   Chen, Cheng ^a   Shen, Xiaoyan ^a   Liu, Peiqing ^a   Huang, Heqing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Advanced glycation end products; Diabetic nephropathy; Oxidative stress; Sirt1 Nrf2 ARE pathway

Indexed keywords

ADVANCED GLYCATION END PRODUCT; COPPER ZINC SUPEROXIDE DISMUTASE; FIBRONECTIN; HEME OXYGENASE 1; SIRTUIN 1; TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA1; NFE2L2 PROTEIN, RAT; SIRT1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING AFFINITY; CELLULAR DISTRIBUTION; DIABETES MELLITUS; DNA BINDING; GEL MOBILITY SHIFT ASSAY; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; KIDNEY INJURY; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; DIABETIC NEPHROPATHY; EXPERIMENTAL DIABETES MELLITUS; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; MALE; METABOLISM; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; BLOTTING, WESTERN; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FIBRONECTINS; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOSYLATION END PRODUCTS, ADVANCED; IMMUNOPRECIPITATION; MALE; MESANGIAL CELLS; NF-E2-RELATED FACTOR 2; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SIRTUIN 1; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84884519280     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.07.029     Document Type: Article

References (42)

1. Y.S. Kanwar, L. Sun, P. Xie, F.Y. Liu, and S. Chen A glimpse of various pathogenetic mechanisms of diabetic nephropathy Annu. Rev. Pathol 6 2011 395 423
2. Y.S. Kanwar, J. Wada, L. Sun, P. Xie, E.I. Wallner, and S. Chen Diabetic nephropathy: mechanisms of renal disease progression Exp. Biol. Med. 233 2008 4 11
3. D. Schlondorff, and B. Banas The mesangial cell revisited: no cell is an island J. Am. Soc. Nephrol. 20 2009 1179 1187
4. H.E. Abboud Mesangial cell biology Exp. Cell Res. 318 2012 979 985
5. S. Dronavalli, I. Duka, and G.L. Bakris The pathogenesis of diabetic nephropathy. Nat. Clin. Pract Endocrinol. Metab. 4 2008 444 452
6. D.K. Singh, P. Winocour, and K. Farrington Oxidative stress in early diabetic nephropathy: fueling the fire Nat. Rev. Endocrinol 7 2011 176 184
7. F. Giacco, and M. Brownlee Oxidative stress and diabetic complications Circ. Res. 107 2010 1058 1070
8. J.M. Forbes, M.T. Coughlan, and M.E. Cooper Oxidative stress as a major culprit in kidney disease in diabetes Diabetes 57 2008 1446 1454
9. Q. Lu, Y.P. Zhai, Q. Cheng, Y.W. Liu, Xing Gao, and T. Zhang The Akt-FoxO3a-manganese superoxide dismutase pathway is involved in the regulation of oxidative stress in diabetic nephropathy Exp. Physiol. 98 2013 934 945
10. N. Kashihara, Y. Haruna, V.K. Kondeti, and Y.S. Kanwar Oxidative stress in diabetic nephropathy Cur. Med. Chem. 17 2010 4256 4269
11. H.B. Lee, M.R. Yu, Y. Yang, Z. Jiang, and H. Ha Reactive oxygen species-regulated signaling pathways in diabetic nephropathy J. Am. Soc. Nephrol. 14 2003 S241 S245
12. H. Ha, and H.B. Lee Reactive oxygen species and matrix remodeling in diabetic kidney J. Am. Soc. Nephrol. 14 2003 S246 S249
13. S. Rahman, and R. Islam Mammalian Sirt1: insights on its biological functions Cell. Commun. Signal 9 2011 1 8
14. Z.Z. Chong, Y.C. Shang, S.H. Wang, and K. Maiese SIRT1: new avenues of discovery for disorders of oxidative stress Expert. Opin. Ther. Targets. 16 2012 167 178
15. B.R. Webster, Z.P. Lu, M.N. Sack, and I. Scott The role of sirtuins in modulating redox stressors Free. Radic. Biol. Med. 52 2012 281 290
16. S. Zhou, H.Z. Chen, Y.Z. Wan, Q.J. Zhang, Y.S. Wei, and S. Huang Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction Circ. Res. 109 2011 639 648
17. J.H. Lee, M.Y. Song, E.K. Song, E.K. Kim, W.S. Moon, and M.K. Han Overexpression of SIRT1 protects pancreatic β-cells against cytokine toxicity by suppressing the nuclear factor-κB signaling pathway Diabetes 58 2009 344 351
18. C. Sun, F. Zhang, X.J. Ge, T.T. Yan, X.M. Chen, and X.L. Shi SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B Cell. Metab. 6 2007 307 319 (Pubitemid 47468091)
19. M. Orimo, T. Minamino, H. Miyauchi, K. Tateno, S. Okada, and J. Moriya Protective role of SIRT1 in diabetic vascular dysfunction Arterioscler. Thromb. Vasc. Biol. 29 2009 889 894
20. T.W. Kensler, N. Wakabayashi, and S. Biswal Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway Annu. Rev. Pharmacol. Toxicol. 47 2007 89 116
21. H. Dreger, K. Westphal, A. Weller, G. Baumann, V. Stangl, and S. Meiners Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection Cardiovasc. Res. 83 2009 354 361
22. T. Jiang, Z.P. Huang, Y.F. Lin, Z.G. Zhang, D.Y. Fang, and D.D. Zhang The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy Diabetes 59 2010 850 860
23. H.T. Zheng, S.A. Whitman, W. Wu, G.T. Wondrak, P.K. Wong, and D. Fang Therapeutic potential of Nrf2 activators in streptozotocin-induced diabetic nephropathy Diabetes 60 2011 3055 3066
24. K. Geoffroy, N. Wiernsperger, M. Lagarde, and S.E. Bawab Bimodal effect of advanced glycation end products on mesangial cell proliferation is mediated by neutral ceramidase regulation and endogenous sphingolipids J. Biol. Chem. 279 2004 34343 34352 (Pubitemid 39318059)
25. Y.B. Xie, J.H. Park, D.K. Kim, J.H. Hwang, S. Oh, and S.B. Park Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation J. Biol. Chem. 284 2009 28762 28774
26. K.P. Huang, W.H. Liu, T. Lan, X. Xie, J. Peng, and J. Huang Berberine reduces fibronectin expression by suppressing the S1P-S1P2 receptor pathway in experimental diabetic nephropathy models PLoS One 7 2012 e43874
27. S.J. Park, F. Ahmad, A. Philp, K. Baar, T. Williams, and H.B. Luo Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases Cell 148 2012 421 433
28. N.L. Price, A.P. Gomes, A.J. Ling, F.V. Duarte, A. Martin-Montalvo, and B.J. North SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function Cell. Metab. 15 2012 675 690
29. C. Schlicker, G. Boanca, M. Lakshminarasimhan, and C. Steegborn Structure-based development of novel sirtuin inhibitors Aging (Albany NY) 3 2011 852 872
30. K. Itoh, J. Mimura, and M. Yamamoto Discovery of the negative regulator of Nrf2, Keap1: A historical overview Antioxid. Redox. Signal. 13 2010 1665 1678
31. T. Wendt, N. Tanji, J.C. Guo, B.I. Hudson, A. Bierhaus, and R. Ramasamy Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy J. Am. Soc. Nephrol. 14 2003 1383 1395 (Pubitemid 36514678)
32. K. Fukami, S. Yamagishi, S. Ueda, and S. Okuda Role of AGEs in diabetic nephropathy Curr. Pharm. Des. 14 2008 946 952 (Pubitemid 351753281)
33. S. Yamagishi, and M. Takanori Advanced glycation end products, oxidative stress and diabetic nephropathy Oxid. Med. Cell. Longev 3 2010 101 108
34. V. Thallas-Bonke, S.R. Thorpe, M.T. Coughlan, K. Fukami, F.Y. Yap, and K.C. Sourris Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-α-dependent pathway Diabetes 57 2008 460 469
35. M.T. Coughlan, D.R. Thorburn, S.A. Penfold, A. Laskowski, B.E. Harcourt, and K.C. Sourris RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes J. Am. Soc. Nephrol. 20 2009 742 752
36. G. Donmez The neurobiology of sirtuins and their role in neurodegeneration Trends. Pharmacol. Sci. 33 2012 494 501
37. R.H. Houtkooper, E. Pirinen, and J. Auwerx Sirtuins as regulators of metabolism and healthspan Nat. Rev. Mol. Cell. Biol. 13 2012 225 238
38. W.J. Cai, M. Ramdas, L. Zhu, X. Chen, G.E. Striker, and H. Vlassaraa Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1 PNAS 109 2012 15888 15893
39. J. Uribarri, W.J. Cai, M. Ramdas, S. Goodman, R. Pyzik, and X. Chen Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes potential role of AGER1 and SIRT1 Diabetes Care 34 2011 1610 1616
40. P.Y. Chuang, Y. Dai, R.J. Liu, H. He, M. Kretzler, and B. Jim Alteration of forkhead Box O (Foxo4) acetylation mediates apoptosis of podocytes in diabetes mellitus PLoS One 6 2011 e23566 2011
41. Z. Ungvari, L. Bailey-Downs, T. Gautam, R. Jimenez, G. Losonczy, and C.H. Zhang Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia Am. J. Physiol. Heart. Circ. Physiol. 300 2011 H1133 H1140
42. M. He, R.C. Siow, D. Sugden, L. Gao, X. Cheng, and G.E. Mann Induction of HO-1 and redox signaling in endothelial cells by advanced glycation end products: a role for Nrf2 in vascular protection in diabetes Nutr. Metab. Cardiovasc. Dis. 21 2011 277 285