메뉴 건너뛰기




Volumn 81, Issue 10, 2013, Pages 3552-3565

Modeling Klebsiella pneumoniae Pathogenesis by Infection of the Wax Moth Galleria mellonella

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; LIPID A; OUTER MEMBRANE PROTEIN;

EID: 84884358610     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00391-13     Document Type: Article
Times cited : (160)

References (66)
  • 1
    • 1042290501 scopus 로고    scopus 로고
    • Activation of dendritic cells: translating innate into adaptive immunity
    • Reise Sousa C. 2004. Activation of dendritic cells: translating innate into adaptive immunity. Curr. Opin. Immunol. 16:21-25.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 21-25
    • Reise Sousa, C.1
  • 2
    • 0035140125 scopus 로고    scopus 로고
    • Drosophila as a model host for Pseudomonas aeruginosa infection
    • D'Argenio DA, Gallagher LA, Berg CA, Manoil C. 2001. Drosophila as a model host for Pseudomonas aeruginosa infection. J. Bacteriol. 183:1466-1471.
    • (2001) J. Bacteriol. , vol.183 , pp. 1466-1471
    • D'Argenio, D.A.1    Gallagher, L.A.2    Berg, C.A.3    Manoil, C.4
  • 3
    • 84864578686 scopus 로고    scopus 로고
    • Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model
    • doi:10.1371/journal.ppat.1002813
    • Feinbaum RL, Urbach JM, Liberati NT, Djonovic S, Adonizio A, Carvunis AR, Ausubel FM. 2012. Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model. PLoS Pathog. 8:e1002813. doi:10.1371/journal.ppat.1002813.
    • (2012) PLoS Pathog. , vol.8
    • Feinbaum, R.L.1    Urbach, J.M.2    Liberati, N.T.3    Djonovic, S.4    Adonizio, A.5    Carvunis, A.R.6    Ausubel, F.M.7
  • 4
    • 0033534534 scopus 로고    scopus 로고
    • Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa- Caenorhabditis elegans pathogenesis model
    • Mahajan-Miklos S, Tan MW, Rahme LG, Ausubel FM. 1999. Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa- Caenorhabditis elegans pathogenesis model. Cell 96:47-56.
    • (1999) Cell , vol.96 , pp. 47-56
    • Mahajan-Miklos, S.1    Tan, M.W.2    Rahme, L.G.3    Ausubel, F.M.4
  • 5
    • 0034735919 scopus 로고    scopus 로고
    • Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans
    • Aballay A, Yorgey P, Ausubel FM. 2000. Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans. Curr. Biol. 10:1539-1542.
    • (2000) Curr. Biol. , vol.10 , pp. 1539-1542
    • Aballay, A.1    Yorgey, P.2    Ausubel, F.M.3
  • 6
    • 14044261186 scopus 로고    scopus 로고
    • Secreted bacterial effectors and host-produced Eiger/TNF drive death in a Salmonella-infected fruit fly
    • doi:10.1371/journal.pbio.0020418.
    • Brandt SM, Dionne MS, Khush RS, Pham LN, Vigdal TJ, Schneider DS. 2004. Secreted bacterial effectors and host-produced Eiger/TNF drive death in a Salmonella-infected fruit fly. PLoS Biol. 2:e418. doi:10.1371/journal.pbio.0020418.
    • (2004) PLoS Biol. , vol.2
    • Brandt, S.M.1    Dionne, M.S.2    Khush, R.S.3    Pham, L.N.4    Vigdal, T.J.5    Schneider, D.S.6
  • 8
    • 69049120321 scopus 로고    scopus 로고
    • Identification of specific and universal virulence factors in Burkholderia cenocepacia strains by using multiple infection hosts
    • Uehlinger S, Schwager S, Bernier SP, Riedel K, Nguyen DT, Sokol PA, Eberl L. 2009. Identification of specific and universal virulence factors in Burkholderia cenocepacia strains by using multiple infection hosts. Infect. Immun. 77:4102-4110.
    • (2009) Infect. Immun. , vol.77 , pp. 4102-4110
    • Uehlinger, S.1    Schwager, S.2    Bernier, S.P.3    Riedel, K.4    Nguyen, D.T.5    Sokol, P.A.6    Eberl, L.7
  • 9
    • 79958082128 scopus 로고    scopus 로고
    • Host-pathogen interactions made transparent with the zebrafish model
    • Meijer AH, Spaink HP. 2011. Host-pathogen interactions made transparent with the zebrafish model. Curr. Drug Targets 12:1000-1017.
    • (2011) Curr. Drug Targets , vol.12 , pp. 1000-1017
    • Meijer, A.H.1    Spaink, H.P.2
  • 10
    • 10944251287 scopus 로고    scopus 로고
    • Genetic models in pathogenesis
    • Pradel E, Ewbank JJ. 2004. Genetic models in pathogenesis. Annu. Rev. Genet. 38:347-363.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 347-363
    • Pradel, E.1    Ewbank, J.J.2
  • 11
    • 84857099099 scopus 로고    scopus 로고
    • Cryptococcus neoformans capsular enlargement and cellular gigantism during Galleria mellonella infection
    • doi:10.1371/journal.pone.0024485
    • Garcia-Rodas R, Casadevall A, Rodriguez-Tudela JL, Cuenca-Estrella M, Zaragoza O. 2011. Cryptococcus neoformans capsular enlargement and cellular gigantism during Galleria mellonella infection. PLoS One 6:e24485. doi:10.1371/journal.pone.0024485.
    • (2011) PLoS One , vol.6
    • Garcia-Rodas, R.1    Casadevall, A.2    Rodriguez-Tudela, J.L.3    Cuenca-Estrella, M.4    Zaragoza, O.5
  • 13
    • 0034123698 scopus 로고    scopus 로고
    • Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects
    • Jander G, Rahme LG, Ausubel FM. 2000. Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects. J. Bacteriol. 182:3843-3845.
    • (2000) J. Bacteriol. , vol.182 , pp. 3843-3845
    • Jander, G.1    Rahme, L.G.2    Ausubel, F.M.3
  • 16
    • 40749107023 scopus 로고    scopus 로고
    • Development of Galleria mellonella as an alternative infection model for the Burkholderia cepacia complex
    • Seed KD, Dennis JJ. 2008. Development of Galleria mellonella as an alternative infection model for the Burkholderia cepacia complex. Infect. Immun. 76:1267-1275.
    • (2008) Infect. Immun. , vol.76 , pp. 1267-1275
    • Seed, K.D.1    Dennis, J.J.2
  • 18
    • 84870523148 scopus 로고    scopus 로고
    • Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
    • Junqueira JC. 2012. Galleria mellonella as a model host for human pathogens: recent studies and new perspectives. Virulence 3:474-476.
    • (2012) Virulence , vol.3 , pp. 474-476
    • Junqueira, J.C.1
  • 19
    • 0030762116 scopus 로고    scopus 로고
    • Clinical, bacteriological, and serological aspects of Klebsiella infections and their spondylarthropathic sequelae
    • Sahly H, Podschun R. 1997. Clinical, bacteriological, and serological aspects of Klebsiella infections and their spondylarthropathic sequelae. Clin. Diagn. Lab. Immunol. 4:393-399.
    • (1997) Clin. Diagn. Lab. Immunol. , vol.4 , pp. 393-399
    • Sahly, H.1    Podschun, R.2
  • 20
    • 62749195559 scopus 로고    scopus 로고
    • The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria
    • Nordmann P, Cuzon G, Naas T. 2009. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect. Dis. 9:228-236.
    • (2009) Lancet Infect. Dis. , vol.9 , pp. 228-236
    • Nordmann, P.1    Cuzon, G.2    Naas, T.3
  • 26
    • 0042825548 scopus 로고    scopus 로고
    • Increased mortality and dysregulated cytokine production in tumor necrosis factor receptor 1-deficient mice following systemic Klebsiella pneumoniae infection
    • Moore TA, Perry ML, Getsoian AG, Monteleon CL, Cogen AL, Standiford TJ. 2003. Increased mortality and dysregulated cytokine production in tumor necrosis factor receptor 1-deficient mice following systemic Klebsiella pneumoniae infection. Infect. Immun. 71:4891-4900.
    • (2003) Infect. Immun. , vol.71 , pp. 4891-4900
    • Moore, T.A.1    Perry, M.L.2    Getsoian, A.G.3    Monteleon, C.L.4    Cogen, A.L.5    Standiford, T.J.6
  • 27
    • 2142726023 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury
    • Moore TA, Lau HY, Cogen AL, Monteleon CL, Standiford TJ. 2003. Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. Shock 20:309-315.
    • (2003) Shock , vol.20 , pp. 309-315
    • Moore, T.A.1    Lau, H.Y.2    Cogen, A.L.3    Monteleon, C.L.4    Standiford, T.J.5
  • 28
    • 28444468452 scopus 로고    scopus 로고
    • Interferon-inducible protein 10, but not monokine induced by gamma interferon, promotes protective type 1 immunity in murine Klebsiella pneumoniae pneumonia
    • Zeng X, Moore TA, Newstead MW, Deng JC, Kunkel SL, Luster AD, Standiford TJ. 2005. Interferon-inducible protein 10, but not monokine induced by gamma interferon, promotes protective type 1 immunity in murine Klebsiella pneumoniae pneumonia. Infect. Immun. 73:8226-8236.
    • (2005) Infect. Immun. , vol.73 , pp. 8226-8236
    • Zeng, X.1    Moore, T.A.2    Newstead, M.W.3    Deng, J.C.4    Kunkel, S.L.5    Luster, A.D.6    Standiford, T.J.7
  • 29
    • 0033541515 scopus 로고    scopus 로고
    • Intrapulmonary tumor necrosis factor gene therapy increases bacterial clearance and survival in murine gramnegative pneumonia
    • Standiford TJ, Wilkowski JM, Sisson TH, Hattori N, Mehrad B, Bucknell KA, Moore TA. 1999. Intrapulmonary tumor necrosis factor gene therapy increases bacterial clearance and survival in murine gramnegative pneumonia. Hum. Gene Ther. 10:899-909.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 899-909
    • Standiford, T.J.1    Wilkowski, J.M.2    Sisson, T.H.3    Hattori, N.4    Mehrad, B.5    Bucknell, K.A.6    Moore, T.A.7
  • 31
    • 6344241187 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection
    • Deng JC, Moore TA, Newstead MW, Zeng X, Krieg AM, Standiford TJ. 2004. CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection. J. Immunol. 173:5148-5155.
    • (2004) J. Immunol. , vol.173 , pp. 5148-5155
    • Deng, J.C.1    Moore, T.A.2    Newstead, M.W.3    Zeng, X.4    Krieg, A.M.5    Standiford, T.J.6
  • 33
    • 79953189021 scopus 로고    scopus 로고
    • Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells
    • March C, Moranta D, Regueiro V, Llobet E, Tomas A, Garmendia J, Bengoechea JA. 2011. Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells. J. Biol. Chem. 286:9956-9967.
    • (2011) J. Biol. Chem. , vol.286 , pp. 9956-9967
    • March, C.1    Moranta, D.2    Regueiro, V.3    Llobet, E.4    Tomas, A.5    Garmendia, J.6    Bengoechea, J.A.7
  • 35
    • 32244433759 scopus 로고    scopus 로고
    • The uptake of a Klebsiella pneumoniae capsule polysaccharide mutant triggers an inflammatory response by human airway epithelial cells
    • Regueiro V, Campos MA, Pons J, Alberti S, Bengoechea JA. 2006. The uptake of a Klebsiella pneumoniae capsule polysaccharide mutant triggers an inflammatory response by human airway epithelial cells. Microbiology 152:555-566.
    • (2006) Microbiology , vol.152 , pp. 555-566
    • Regueiro, V.1    Campos, M.A.2    Pons, J.3    Alberti, S.4    Bengoechea, J.A.5
  • 37
    • 33748066974 scopus 로고    scopus 로고
    • Comparison of the host responses to wild-type and cpsB mutant Klebsiella pneumoniae infections
    • Lawlor MS, Handley SA, Miller VL. 2006. Comparison of the host responses to wild-type and cpsB mutant Klebsiella pneumoniae infections. Infect. Immun. 74:5402-5407.
    • (2006) Infect. Immun. , vol.74 , pp. 5402-5407
    • Lawlor, M.S.1    Handley, S.A.2    Miller, V.L.3
  • 38
    • 84870543271 scopus 로고    scopus 로고
    • Effect of nutrient deprivation on the susceptibility of Galleria mellonella larvae to infection
    • Banville N, Browne N, Kavanagh K. 2012. Effect of nutrient deprivation on the susceptibility of Galleria mellonella larvae to infection. Virulence 3:497-503.
    • (2012) Virulence , vol.3 , pp. 497-503
    • Banville, N.1    Browne, N.2    Kavanagh, K.3
  • 39
    • 0019807050 scopus 로고
    • A computer program for estimating LD50 and its confidence limits using modified Behrens-Reed-Muench cumulant method
    • Thakur AK, Fezio WL. 1981. A computer program for estimating LD50 and its confidence limits using modified Behrens-Reed-Muench cumulant method. Drug Chem. Toxicol. 4:297-305.
    • (1981) Drug Chem. Toxicol. , vol.4 , pp. 297-305
    • Thakur, A.K.1    Fezio, W.L.2
  • 40
    • 33746301405 scopus 로고    scopus 로고
    • RNAi suppression of recognition protein mediated immune responses in the tobacco hornworm Manduca sexta causes increased susceptibility to the insect pathogen Photorhabdus
    • Eleftherianos I, Millichap PJ, Ffrench-Constant RH, Reynolds SE. 2006. RNAi suppression of recognition protein mediated immune responses in the tobacco hornworm Manduca sexta causes increased susceptibility to the insect pathogen Photorhabdus. Dev. Comp. Immunol. 30:1099-1107.
    • (2006) Dev. Comp. Immunol. , vol.30 , pp. 1099-1107
    • Eleftherianos, I.1    Millichap, P.J.2    Ffrench-Constant, R.H.3    Reynolds, S.E.4
  • 41
    • 0029843338 scopus 로고    scopus 로고
    • Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction
    • Valdivia RH, Falkow S. 1996. Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Mol. Microbiol. 22:367-378.
    • (1996) Mol. Microbiol. , vol.22 , pp. 367-378
    • Valdivia, R.H.1    Falkow, S.2
  • 42
    • 0030866940 scopus 로고    scopus 로고
    • Fluorescence-based isolation of bacterial genes expressed within host cells
    • Valdivia RH, Falkow S. 1997. Fluorescence-based isolation of bacterial genes expressed within host cells. Science 277:2007-2011.
    • (1997) Science , vol.277 , pp. 2007-2011
    • Valdivia, R.H.1    Falkow, S.2
  • 44
    • 58949097012 scopus 로고    scopus 로고
    • Capsule polysaccharide is a bacterial decoy for antimicrobial peptides
    • Llobet E, Tomas JM, Bengoechea JA. 2008. Capsule polysaccharide is a bacterial decoy for antimicrobial peptides. Microbiology 154:3877-3886.
    • (2008) Microbiology , vol.154 , pp. 3877-3886
    • Llobet, E.1    Tomas, J.M.2    Bengoechea, J.A.3
  • 45
    • 1242351240 scopus 로고    scopus 로고
    • Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens
    • Kavanagh K, Reeves EP. 2004. Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens. FEMS Microbiol. Rev. 28:101-112.
    • (2004) FEMS Microbiol. Rev. , vol.28 , pp. 101-112
    • Kavanagh, K.1    Reeves, E.P.2
  • 46
    • 0029809576 scopus 로고    scopus 로고
    • Pho-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance
    • Gunn JS, Miller SI. 1996. Pho-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance. J. Bacteriol. 178:6857-6864.
    • (1996) J. Bacteriol. , vol.178 , pp. 6857-6864
    • Gunn, J.S.1    Miller, S.I.2
  • 47
    • 69149106013 scopus 로고    scopus 로고
    • Klebsiella pneumoniae triggers a cytotoxic effect on airway epithelial cells
    • doi:10.1186/1471-2180-9-156
    • Cano V, Moranta D, Llobet-Brossa E, Bengoechea JA, Garmendia J. 2009. Klebsiella pneumoniae triggers a cytotoxic effect on airway epithelial cells. BMC Microbiol. 9:156. doi:10.1186/1471-2180-9-156.
    • (2009) BMC Microbiol. , vol.9 , pp. 156
    • Cano, V.1    Moranta, D.2    Llobet-Brossa, E.3    Bengoechea, J.A.4    Garmendia, J.5
  • 48
    • 0036176052 scopus 로고    scopus 로고
    • Role of lung epithelial cells in defense against Klebsiella pneumoniae pneumonia
    • Cortes G, Alvarez D, Saus C, Alberti S. 2002. Role of lung epithelial cells in defense against Klebsiella pneumoniae pneumonia. Infect. Immun. 70: 1075-1080.
    • (2002) Infect. Immun. , vol.70 , pp. 1075-1080
    • Cortes, G.1    Alvarez, D.2    Saus, C.3    Alberti, S.4
  • 49
    • 61449244620 scopus 로고    scopus 로고
    • Dictyostelium discoideum: a model host to measure bacterial virulence
    • Froquet R, Lelong E, Marchetti A, Cosson P. 2009. Dictyostelium discoideum: a model host to measure bacterial virulence. Nat. Protoc. 4:25-30.
    • (2009) Nat. Protoc. , vol.4 , pp. 25-30
    • Froquet, R.1    Lelong, E.2    Marchetti, A.3    Cosson, P.4
  • 50
    • 0027184112 scopus 로고
    • The role of the O-antigen lipopolysaccharide and capsule on an experimental Klebsiella pneumoniae infection of the rat urinary tract
    • Camprubi S, Merino S, Benedi VJ, Tomas JM. 1993. The role of the O-antigen lipopolysaccharide and capsule on an experimental Klebsiella pneumoniae infection of the rat urinary tract. FEMS Microbiol. Lett. 111: 9-13.
    • (1993) FEMS Microbiol. Lett. , vol.111 , pp. 9-13
    • Camprubi, S.1    Merino, S.2    Benedi, V.J.3    Tomas, J.M.4
  • 51
    • 0036117885 scopus 로고    scopus 로고
    • Molecular analysis of the contribution of the capsular polysaccharide and the lipopolysaccharide O side chain to the virulence of Klebsiella pneumoniae in a murine model of pneumonia
    • Cortes G, Borrell N, de Astorza B, Gomez C, Sauleda J, Alberti S. 2002. Molecular analysis of the contribution of the capsular polysaccharide and the lipopolysaccharide O side chain to the virulence of Klebsiella pneumoniae in a murine model of pneumonia. Infect. Immun. 70:2583-2590.
    • (2002) Infect. Immun. , vol.70 , pp. 2583-2590
    • Cortes, G.1    Borrell, N.2    de Astorza, B.3    Gomez, C.4    Sauleda, J.5    Alberti, S.6
  • 52
    • 27944510065 scopus 로고    scopus 로고
    • Identification of Klebsiella pneumoniae virulence determinants using an intranasal infection model
    • Lawlor MS, Hsu J, Rick PD, Miller VL. 2005. Identification of Klebsiella pneumoniae virulence determinants using an intranasal infection model. Mol. Microbiol. 58:1054-1073.
    • (2005) Mol. Microbiol. , vol.58 , pp. 1054-1073
    • Lawlor, M.S.1    Hsu, J.2    Rick, P.D.3    Miller, V.L.4
  • 54
    • 80052326581 scopus 로고    scopus 로고
    • Analysis of the networks controlling the antimicrobial peptide-dependent induction of Klebsiella pneumoniae virulence factors
    • Llobet E, Campos MA, Gimenez P, Moranta D, Bengoechea JA. 2011. Analysis of the networks controlling the antimicrobial peptide-dependent induction of Klebsiella pneumoniae virulence factors. Infect. Immun. 79: 3718-3732.
    • (2011) Infect. Immun. , vol.79 , pp. 3718-3732
    • Llobet, E.1    Campos, M.A.2    Gimenez, P.3    Moranta, D.4    Bengoechea, J.A.5
  • 57
    • 0031792165 scopus 로고    scopus 로고
    • Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors
    • Podschun R, Ullmann U. 1998. Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin. Microbiol. Rev. 11:589-603.
    • (1998) Clin. Microbiol. Rev. , vol.11 , pp. 589-603
    • Podschun, R.1    Ullmann, U.2
  • 58
    • 0033963553 scopus 로고    scopus 로고
    • Capsular polysaccharide is a major complement resistance factor in lipopolysaccharide O side chain-deficient Klebsiella pneumoniae clinical isolates
    • Alvarez D, Merino S, Tomas JM, Benedi VJ, Alberti S. 2000. Capsular polysaccharide is a major complement resistance factor in lipopolysaccharide O side chain-deficient Klebsiella pneumoniae clinical isolates. Infect. Immun. 68:953-955.
    • (2000) Infect. Immun. , vol.68 , pp. 953-955
    • Alvarez, D.1    Merino, S.2    Tomas, J.M.3    Benedi, V.J.4    Alberti, S.5
  • 61
    • 79961121513 scopus 로고    scopus 로고
    • Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2
    • Bachman MA, Oyler JE, Burns SH, Caza M, Lepine F, Dozois CM, Weiser JN. 2011. Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2. Infect. Immun. 79: 3309-3316.
    • (2011) Infect. Immun. , vol.79 , pp. 3309-3316
    • Bachman, M.A.1    Oyler, J.E.2    Burns, S.H.3    Caza, M.4    Lepine, F.5    Dozois, C.M.6    Weiser, J.N.7
  • 62
    • 63449117143 scopus 로고    scopus 로고
    • Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization
    • doi:10.1371/journal.pone.0004982
    • Brisse S, Fevre C, Passet V, Issenhuth-Jeanjean S, Tournebize R, Diancourt L, Grimont P. 2009. Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization. PLoS One 4:e4982. doi:10.1371/journal.pone.0004982.
    • (2009) PLoS One , vol.4
    • Brisse, S.1    Fevre, C.2    Passet, V.3    Issenhuth-Jeanjean, S.4    Tournebize, R.5    Diancourt, L.6    Grimont, P.7
  • 64
    • 1542313887 scopus 로고    scopus 로고
    • A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications
    • Fang CT, Chuang YP, Shun CT, Chang SC, Wang JT. 2004. A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications. J. Exp. Med. 199:697-705.
    • (2004) J. Exp. Med. , vol.199 , pp. 697-705
    • Fang, C.T.1    Chuang, Y.P.2    Shun, C.T.3    Chang, S.C.4    Wang, J.T.5
  • 65
    • 84863273999 scopus 로고    scopus 로고
    • Lipopolysaccharide O1 antigen contributes to the virulence in Klebsiella pneumoniae causing pyogenic liver abscess
    • doi:10.1371/journal.pone.0033155
    • Hsieh PF, Lin TL, Yang FL, Wu MC, Pan YJ, Wu SH, Wang JT. 2012. Lipopolysaccharide O1 antigen contributes to the virulence in Klebsiella pneumoniae causing pyogenic liver abscess. PLoS One 7:e33155. doi:10.1371/journal.pone.0033155.
    • (2012) PLoS One , vol.7
    • Hsieh, P.F.1    Lin, T.L.2    Yang, F.L.3    Wu, M.C.4    Pan, Y.J.5    Wu, S.H.6    Wang, J.T.7
  • 66
    • 0024497512 scopus 로고
    • Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor
    • Nassif X, Fournier JM, Arondel J, Sansonetti PJ. 1989. Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor. Infect. Immun. 57:546-552.
    • (1989) Infect. Immun. , vol.57 , pp. 546-552
    • Nassif, X.1    Fournier, J.M.2    Arondel, J.3    Sansonetti, P.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.