메뉴 건너뛰기




Volumn 210, Issue 8, 2013, Pages 1591-1601

CD4+ T helper cells use CD154-CD40 interactions to counteract T reg cell- mediated suppression of CD8+ T cell responses to influenza

Author keywords

[No Author keywords available]

Indexed keywords

CD40 LIGAND MONOCLONAL ANTIBODY;

EID: 84884258239     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20130097     Document Type: Article
Times cited : (37)

References (63)
  • 1
    • 1642269154 scopus 로고    scopus 로고
    • Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key
    • Bachmann, M.F., L. Hunziker, R.M. Zinkernagel, T. Storni, and M. Kopf. 2004. Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key. Eur. J. Immunol. 34:317- 326. http://dx.doi.org/10.1002/eji.200324717
    • (2004) Eur. J. Immunol. , vol.34
    • Bachmann, M.F.1    Hunziker, L.2    Zinkernagel, R.M.3    Storni, T.4    Kopf, M.5
  • 2
    • 76949094170 scopus 로고    scopus 로고
    • Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza
    • Ballesteros-Tato, A., B. León, F.E. Lund, and T.D. Randall. 2010. Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza. Nat. Immunol. 11:216-224. http://dx.doi.org/10.1038/ni.1838
    • (2010) Nat. Immunol. , vol.11 , pp. 216-224
    • Ballesteros-Tato, A.1    León, B.2    Lund, F.E.3    Randall, T.D.4
  • 4
    • 0036889420 scopus 로고    scopus 로고
    • Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)- T-cell-deficient mice
    • Belz, G.T., D. Wodarz, G. Diaz, M.A. Nowak, and P.C. Doherty. 2002. Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)- T-cell-deficient mice. J. Virol. 76:12388-12393. http://dx.doi.org/10 .1128/JVI.76.23.12388-12393.2002
    • (2002) J. Virol. , vol.76 , pp. 12388-12393
    • Belz, G.T.1    Wodarz, D.2    Diaz, G.3    Nowak, M.A.4    Doherty, P.C.5
  • 5
  • 7
    • 0037144612 scopus 로고    scopus 로고
    • A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory
    • Bourgeois, C., B. Rocha, and C. Tanchot. 2002. A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory. Science. 297:2060-2063. http://dx.doi.org/10.1126/science.1072615
    • (2002) Science. , vol.297 , pp. 2060-2063
    • Bourgeois, C.1    Rocha, B.2    Tanchot, C.3
  • 9
    • 79961153751 scopus 로고    scopus 로고
    • Treg cells: patrolling a dangerous neighborhood
    • Campbell, D.J., and M.A. Koch. 2011. Treg cells: patrolling a dangerous neighborhood. Nat. Med. 17:929-930. http://dx.doi.org/10.1038/nm.2433
    • (2011) Nat. Med. , vol.17 , pp. 929-930
    • Campbell, D.J.1    Koch, M.A.2
  • 10
    • 60749098750 scopus 로고    scopus 로고
    • CD40 regulates human dendritic cell-derived IL-7 production that, in turn, contributes to CD8(+) T-cell antigen-specific expansion
    • Carreno, B.M., M. Becker-Hapak, and G.P. Linette. 2009. CD40 regulates human dendritic cell-derived IL-7 production that, in turn, contributes to CD8(+) T-cell antigen-specific expansion. Immunol. Cell Biol. 87:167-177. http://dx.doi.org/10.1038/icb.2008.80
    • (2009) Immunol. Cell Biol. , vol.87 , pp. 167-177
    • Carreno, B.M.1    Becker-Hapak, M.2    Linette, G.P.3
  • 13
    • 79952294178 scopus 로고    scopus 로고
    • Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points
    • Dietze, K.K., G. Zelinskyy, K. Gibbert, S. Schimmer, S. Francois, L. Myers, T. Sparwasser, K.J. Hasenkrug, and U. Dittmer. 2011. Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points. Proc. Natl. Acad. Sci. USA. 108:2420-2425. http://dx.doi.org/10.1073/pnas.1015148108
    • (2011) Proc. Natl. Acad. Sci. USA. , vol.108 , pp. 2420-2425
    • Dietze, K.K.1    Zelinskyy, G.2    Gibbert, K.3    Schimmer, S.4    Francois, S.5    Myers, L.6    Sparwasser, T.7    Hasenkrug, K.J.8    Dittmer, U.9
  • 14
    • 49149109920 scopus 로고    scopus 로고
    • Late signals from CD27 prevent Fas-dependent apoptosis of primary CD8+ T cells
    • Dolfi, D.V., A.C. Boesteanu, C. Petrovas, D. Xia, E.A. Butz, and P.D. Katsikis. 2008. Late signals from CD27 prevent Fas-dependent apoptosis of primary CD8+ T cells. J. Immunol. 180:2912-2921.
    • (2008) J. Immunol. , vol.180 , pp. 2912-2921
    • Dolfi, D.V.1    Boesteanu, A.C.2    Petrovas, C.3    Xia, D.4    Butz, E.A.5    Katsikis, P.D.6
  • 15
    • 65349149089 scopus 로고    scopus 로고
    • Molecular mechanism and function of CD40/CD40L engagement in the immune system
    • Elgueta, R., M.J. Benson, V.C. de Vries, A. Wasiuk, Y. Guo, and R.J. Noelle. 2009. Molecular mechanism and function of CD40/CD40L engagement in the immune system. Immunol. Rev. 229:152-172. http://dx.doi.org/10.1111/j.1600-065X.2009.00782.x
    • (2009) Immunol. Rev. , vol.229 , pp. 152-172
    • Elgueta, R.1    Benson, M.J.2    de Vries, V.C.3    Wasiuk, A.4    Guo, Y.5    Noelle, R.J.6
  • 16
    • 80052038585 scopus 로고    scopus 로고
    • Autocrine IL-2 is required for secondary population expansion of CD8(+) memory T cells
    • Feau, S., R. Arens, S. Togher, and S.P. Schoenberger. 2011. Autocrine IL-2 is required for secondary population expansion of CD8(+) memory T cells. Nat. Immunol. 12:908-913. http://dx.doi.org/10.1038/ni.2079
    • (2011) Nat. Immunol. , vol.12 , pp. 908-913
    • Feau, S.1    Arens, R.2    Togher, S.3    Schoenberger, S.P.4
  • 17
    • 84864864594 scopus 로고    scopus 로고
    • The CD4+ T-cell help signal is transmitted from APC to CD8+ T-cells via CD27-CD70 interactions
    • Feau, S., Z. Garcia, R. Arens, H. Yagita, J. Borst, and S.P. Schoenberger. 2012. The CD4+ T-cell help signal is transmitted from APC to CD8+ T-cells via CD27-CD70 interactions. Nat Commun. 3:948. http://dx.doi.org/10.1038/ncomms1948
    • (2012) Nat Commun. , vol.3 , pp. 948
    • Feau, S.1    Garcia, Z.2    Arens, R.3    Yagita, H.4    Borst, J.5    Schoenberger, S.P.6
  • 19
    • 3042545974 scopus 로고    scopus 로고
    • The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation
    • Fujii, S., K. Liu, C. Smith, A.J. Bonito, and R.M. Steinman. 2004. The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation. J. Exp. Med. 199:1607-1618. http://dx.doi.org/10.1084/jem.20040317
    • (2004) J. Exp. Med. , vol.199 , pp. 1607-1618
    • Fujii, S.1    Liu, K.2    Smith, C.3    Bonito, A.J.4    Steinman, R.M.5
  • 20
    • 77956913784 scopus 로고    scopus 로고
    • Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection
    • Fulton, R.B., D.K. Meyerholz, and S.M. Varga. 2010. Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection. J. Immunol. 185:2382-2392. http://dx.doi.org/10.4049/jimmunol.1000423
    • (2010) J. Immunol. , vol.185 , pp. 2382-2392
    • Fulton, R.B.1    Meyerholz, D.K.2    Varga, S.M.3
  • 21
    • 77954913409 scopus 로고    scopus 로고
    • Control systems and decision making for antibody production
    • Goodnow, C.C., C.G. Vinuesa, K.L. Randall, F. Mackay, and R. Brink. 2010. Control systems and decision making for antibody production. Nat. Immunol. 11:681-688. http://dx.doi.org/10.1038/ni.1900
    • (2010) Nat. Immunol. , vol.11 , pp. 681-688
    • Goodnow, C.C.1    Vinuesa, C.G.2    Randall, K.L.3    Mackay, F.4    Brink, R.5
  • 22
    • 77954112755 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells utilize FasL as a mechanism to restrict DC priming functions in cutaneous immune responses
    • Gorbachev, A.V., and R.L. Fairchild. 2010. CD4+CD25+ regulatory T cells utilize FasL as a mechanism to restrict DC priming functions in cutaneous immune responses. Eur. J. Immunol. 40:2006-2015. http://dx.doi.org/10.1002/eji.200939387
    • (2010) Eur. J. Immunol. , vol.40 , pp. 2006-2015
    • Gorbachev, A.V.1    Fairchild, R.L.2
  • 23
    • 0035889919 scopus 로고    scopus 로고
    • Listeria monocytogenes infection overcomes the requirement for CD40 ligand in exogenous antigen presentation to CD8(+)T cells
    • Hamilton, S.E., A.R. Tvinnereim, and J.T. Harty. 2001. Listeria monocytogenes infection overcomes the requirement for CD40 ligand in exogenous antigen presentation to CD8(+)T cells. J. Immunol. 167:5603-5609.
    • (2001) J. Immunol. , vol.167 , pp. 5603-5609
    • Hamilton, S.E.1    Tvinnereim, A.R.2    Harty, J.T.3
  • 26
    • 33847388793 scopus 로고    scopus 로고
    • CD40-CD40 ligand interaction between dendritic cells and CD8+ T cells is needed to stimulate maximal T cell responses in the absence of CD4+ T cell help
    • Hernandez, M.G., L. Shen, and K.L. Rock. 2007. CD40-CD40 ligand interaction between dendritic cells and CD8+ T cells is needed to stimulate maximal T cell responses in the absence of CD4+ T cell help. J. Immunol. 178:2844-2852.
    • (2007) J. Immunol. , vol.178 , pp. 2844-2852
    • Hernandez, M.G.1    Shen, L.2    Rock, K.L.3
  • 27
    • 44449085472 scopus 로고    scopus 로고
    • CD40 on APCs is needed for optimal programming, maintenance, and recall of CD8+ T cell memory even in the absence of CD4+ T cell help
    • Hernandez, M.G., L. Shen, and K.L. Rock. 2008. CD40 on APCs is needed for optimal programming, maintenance, and recall of CD8+ T cell memory even in the absence of CD4+ T cell help. J. Immunol. 180:4382-4390.
    • (2008) J. Immunol. , vol.180 , pp. 4382-4390
    • Hernandez, M.G.1    Shen, L.2    Rock, K.L.3
  • 29
    • 0037877918 scopus 로고    scopus 로고
    • CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation
    • Inwald, D.P., A. McDowall, M.J. Peters, R.E. Callard, and N.J. Klein. 2003. CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation. Circ. Res. 92:1041-1048. http://dx.doi.org/10.1161/01.RES.0000070111.98158.6C
    • (2003) Circ. Res. , vol.92 , pp. 1041-1048
    • Inwald, D.P.1    McDowall, A.2    Peters, M.J.3    Callard, R.E.4    Klein, N.J.5
  • 30
    • 60149106361 scopus 로고    scopus 로고
    • Selected Toll-like receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells
    • Johnson, S., Y. Zhan, R.M. Sutherland, A.M. Mount, S. Bedoui, J.L. Brady, E.M. Carrington, L.E. Brown, G.T. Belz, W.R. Heath, and A.M. Lew. 2009. Selected Toll-like receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells. Immunity. 30:218-227. http://dx.doi.org/10.1016/j.immuni.2008.11.015
    • (2009) Immunity. , vol.30 , pp. 218-227
    • Johnson, S.1    Zhan, Y.2    Sutherland, R.M.3    Mount, A.M.4    Bedoui, S.5    Brady, J.L.6    Carrington, E.M.7    Brown, L.E.8    Belz, G.T.9    Heath, W.R.10    Lew, A.M.11
  • 31
    • 18644375874 scopus 로고    scopus 로고
    • In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens
    • Jung, S., D. Unutmaz, P. Wong, G. Sano, K. De los Santos, T. Sparwasser, S. Wu, S. Vuthoori, K. Ko, F. Zavala, et al. 2002. In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity. 17:211-220. http://dx.doi.org/10.1016/S1074-7613(02)00365-5
    • (2002) Immunity. , vol.17 , pp. 211-220
    • Jung, S.1    Unutmaz, D.2    Wong, P.3    Sano, G.4    De los Santos, K.5    Sparwasser, T.6    Wu, S.7    Vuthoori, S.8    Ko, K.9    Zavala, F.10
  • 32
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech, S.M., J.T. Tan, E.J. Wherry, B.T. Konieczny, C.D. Surh, and R. Ahmed. 2003. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 4:1191-1198. http://dx.doi.org/10.1038/ni1009
    • (2003) Nat. Immunol. , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 33
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim, J.M., J.P. Rasmussen, and A.Y. Rudensky. 2007. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8:191-197. http://dx.doi.org/10.1038/ni1428
    • (2007) Nat. Immunol. , vol.8 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 34
    • 77952838480 scopus 로고    scopus 로고
    • Cross-priming in health and disease
    • Kurts, C., B.W. Robinson, and P.A. Knolle. 2010. Cross-priming in health and disease. Nat. Rev. Immunol. 10:403-414. http://dx.doi.org/10.1038/nri2780
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 403-414
    • Kurts, C.1    Robinson, B.W.2    Knolle, P.A.3
  • 35
    • 0036717296 scopus 로고    scopus 로고
    • The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: Reciprocal regulation by interleukin (IL)-4 and IL-12
    • Lee, B.O., L. Haynes, S.M. Eaton, S.L. Swain, and T.D. Randall. 2002. The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: Reciprocal regulation by interleukin (IL)-4 and IL-12. J. Exp. Med. 196:693-704. http://dx.doi.org/10.1084/jem.20020845
    • (2002) J. Exp. Med. , vol.196 , pp. 693-704
    • Lee, B.O.1    Haynes, L.2    Eaton, S.M.3    Swain, S.L.4    Randall, T.D.5
  • 36
    • 0344305402 scopus 로고    scopus 로고
    • CD40-deficient, influenzaspecific CD8 memory T cells develop and function normally in a CD40-sufficient environment
    • Lee, B.O., L. Hartson, and T.D. Randall. 2003a. CD40-deficient, influenzaspecific CD8 memory T cells develop and function normally in a CD40-sufficient environment. J. Exp. Med. 198:1759-1764. http://dx.doi.org/10.1084/jem.20031440
    • (2003) J. Exp. Med. , vol.198 , pp. 1759-1764
    • Lee, B.O.1    Hartson, L.2    Randall, T.D.3
  • 38
    • 84862592738 scopus 로고    scopus 로고
    • Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells
    • León, B., A. Ballesteros-Tato, J.L. Browning, R. Dunn, T.D. Randall, and F.E. Lund. 2012. Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells. Nat. Immunol. 13:681-690. http://dx.doi.org/10.1038/ni.2309
    • (2012) Nat. Immunol. , vol.13 , pp. 681-690
    • León, B.1    Ballesteros-Tato, A.2    Browning, J.L.3    Dunn, R.4    Randall, T.D.5    Lund, F.E.6
  • 40
    • 33646186619 scopus 로고    scopus 로고
    • Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis
    • Ma, A., R. Koka, and P. Burkett. 2006. Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis. Annu. Rev. Immunol. 24:657-679. http://dx.doi.org/10.1146/annurev.immunol.24.021605.090727
    • (2006) Annu. Rev. Immunol. , vol.24 , pp. 657-679
    • Ma, A.1    Koka, R.2    Burkett, P.3
  • 41
    • 0036891883 scopus 로고    scopus 로고
    • Upregulation of CD40 expression on endothelial cells infected with human cytomegalovirus
    • Maisch, T., B. Kropff, C. Sinzger, and M. Mach. 2002. Upregulation of CD40 expression on endothelial cells infected with human cytomegalovirus. J. Virol. 76:12803-12812. http://dx.doi.org/10.1128/JVI.76 .24.12803-12812.2002
    • (2002) J. Virol. , vol.76 , pp. 12803-12812
    • Maisch, T.1    Kropff, B.2    Sinzger, C.3    Mach, M.4
  • 42
    • 46949088340 scopus 로고    scopus 로고
    • Protective influenzaspecific CD8 T cell responses require interactions with dendritic cells in the lungs
    • McGill, J., N. Van Rooijen, and K.L. Legge. 2008. Protective influenzaspecific CD8 T cell responses require interactions with dendritic cells in the lungs. J. Exp. Med. 205:1635-1646. http://dx.doi.org/10.1084/jem.20080314
    • (2008) J. Exp. Med. , vol.205 , pp. 1635-1646
    • McGill, J.1    Van Rooijen, N.2    Legge, K.L.3
  • 43
    • 77949518873 scopus 로고    scopus 로고
    • IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection
    • McGill, J., N. Van Rooijen, and K.L. Legge. 2010. IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection. J. Exp. Med. 207:521-534. http://dx.doi.org/10.1084/jem.20091711
    • (2010) J. Exp. Med. , vol.207 , pp. 521-534
    • McGill, J.1    Van Rooijen, N.2    Legge, K.L.3
  • 44
    • 79956296631 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis
    • McNally, A., G.R. Hill, T. Sparwasser, R. Thomas, and R.J. Steptoe. 2011. CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proc. Natl. Acad. Sci. USA. 108:7529-7534. http://dx.doi.org/10.1073/pnas.1103782108
    • (2011) Proc. Natl. Acad. Sci. USA. , vol.108 , pp. 7529-7534
    • McNally, A.1    Hill, G.R.2    Sparwasser, T.3    Thomas, R.4    Steptoe, R.J.5
  • 45
    • 70349085260 scopus 로고    scopus 로고
    • Functional roles for T cell CD40 in infection and autoimmune disease: the role of CD40 in lymphocyte homeostasis
    • Munroe, M.E. 2009. Functional roles for T cell CD40 in infection and autoimmune disease: the role of CD40 in lymphocyte homeostasis. Semin. Immunol. 21:283-288. http://dx.doi.org/10.1016/j.smim.2009.05.008
    • (2009) Semin. Immunol. , vol.21 , pp. 283-288
    • Munroe, M.E.1
  • 46
    • 36248976097 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivationmediated apoptosis of effector CD4+ T cells
    • Pandiyan, P., L. Zheng, S. Ishihara, J. Reed, and M.J. Lenardo. 2007. CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivationmediated apoptosis of effector CD4+ T cells. Nat. Immunol. 8:1353-1362. http://dx.doi.org/10.1038/ni1536
    • (2007) Nat. Immunol. , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 47
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • Pasare, C., and R. Medzhitov. 2003. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science. 299:1033-1036. http://dx.doi.org/10.1126/science.1078231
    • (2003) Science. , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 48
    • 0032482337 scopus 로고    scopus 로고
    • A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
    • Ridge, J.P., F. Di Rosa, and P. Matzinger. 1998. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature. 393:474-478. http://dx.doi.org/10.1038/30989
    • (1998) Nature. , vol.393 , pp. 474-478
    • Ridge, J.P.1    Di Rosa, F.2    Matzinger, P.3
  • 49
    • 0032482474 scopus 로고    scopus 로고
    • T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
    • Schoenberger, S.P., R.E. Toes, E.I. van der Voort, R. Offringa, and C.J. Melief. 1998. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature. 393:480-483. http://dx.doi.org/10.1038/31002
    • (1998) Nature. , vol.393 , pp. 480-483
    • Schoenberger, S.P.1    Toes, R.E.2    van der Voort, E.I.3    Offringa, R.4    Melief, C.J.5
  • 50
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock, D.J., and H. Shen. 2003. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science. 300:337-339. http://dx.doi.org/10.1126/science.1082305
    • (2003) Science. , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 51
    • 0037442136 scopus 로고    scopus 로고
    • Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection
    • Shedlock, D.J., J.K. Whitmire, J. Tan, A.S. MacDonald, R. Ahmed, and H. Shen. 2003. Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection. J. Immunol. 170:2053-2063.
    • (2003) J. Immunol. , vol.170 , pp. 2053-2063
    • Shedlock, D.J.1    Whitmire, J.K.2    Tan, J.3    MacDonald, A.S.4    Ahmed, R.5    Shen, H.6
  • 53
    • 0033230839 scopus 로고    scopus 로고
    • CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site
    • Sonoda, K.H., M. Exley, S. Snapper, S.P. Balk, and J. Stein-Streilein. 1999. CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site. J. Exp. Med. 190:1215-1226. http://dx.doi.org/10.1084/jem.190.9.1215
    • (1999) J. Exp. Med. , vol.190 , pp. 1215-1226
    • Sonoda, K.H.1    Exley, M.2    Snapper, S.3    Balk, S.P.4    Stein-Streilein, J.5
  • 54
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun, J.C., and M.J. Bevan. 2003. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science. 300:339-342. http://dx.doi.org/10.1126/science.1083317
    • (2003) Science. , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 55
    • 0141449974 scopus 로고    scopus 로고
    • CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses
    • Suvas, S., U. Kumaraguru, C.D. Pack, S. Lee, and B.T. Rouse. 2003. CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses. J. Exp. Med. 198:889-901. http://dx.doi.org/10.1084/jem.20030171
    • (2003) J. Exp. Med. , vol.198 , pp. 889-901
    • Suvas, S.1    Kumaraguru, U.2    Pack, C.D.3    Lee, S.4    Rouse, B.T.5
  • 56
    • 58849158737 scopus 로고    scopus 로고
    • Different T cell receptor signals determine CD8+ memory versus effector development
    • Teixeiro, E., M.A. Daniels, S.E. Hamilton, A.G. Schrum, R. Bragado, S.C. Jameson, and E. Palmer. 2009. Different T cell receptor signals determine CD8+ memory versus effector development. Science. 323:502-505. http://dx.doi.org/10.1126/science.1163612
    • (2009) Science. , vol.323 , pp. 502-505
    • Teixeiro, E.1    Daniels, M.A.2    Hamilton, S.E.3    Schrum, A.G.4    Bragado, R.5    Jameson, S.C.6    Palmer, E.7
  • 58
    • 77955898582 scopus 로고    scopus 로고
    • T cells and follicular dendritic cells in germinal center B-cell formation and selection
    • Vinuesa, C.G., M.A. Linterman, C.C. Goodnow, and K.L. Randall. 2010. T cells and follicular dendritic cells in germinal center B-cell formation and selection. Immunol. Rev. 237:72-89. http://dx.doi.org/10.1111/j.1600-065X.2010.00937.x
    • (2010) Immunol. Rev. , vol.237 , pp. 72-89
    • Vinuesa, C.G.1    Linterman, M.A.2    Goodnow, C.C.3    Randall, K.L.4
  • 59
    • 0035717978 scopus 로고    scopus 로고
    • Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells
    • Voeten, J.T., G.F. Rimmelzwaan, N.J. Nieuwkoop, R.A. Fouchier, and A.D. Osterhaus. 2001. Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells. Clin. Exp. Immunol. 125:423-431. http://dx.doi.org/10.1046/j.1365-2249.2001.01613.x
    • (2001) Clin. Exp. Immunol. , vol.125 , pp. 423-431
    • Voeten, J.T.1    Rimmelzwaan, G.F.2    Nieuwkoop, N.J.3    Fouchier, R.A.4    Osterhaus, A.D.5
  • 60
    • 0029861758 scopus 로고    scopus 로고
    • CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection
    • Whitmire, J.K., M.K. Slifka, I.S. Grewal, R.A. Flavell, and R. Ahmed. 1996. CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection. J. Virol. 70:8375-8381.
    • (1996) J. Virol. , vol.70 , pp. 8375-8381
    • Whitmire, J.K.1    Slifka, M.K.2    Grewal, I.S.3    Flavell, R.A.4    Ahmed, R.5
  • 61
    • 0033568301 scopus 로고    scopus 로고
    • CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses
    • Whitmire, J.K., R.A. Flavell, I.S. Grewal, C.P. Larsen, T.C. Pearson, and R. Ahmed. 1999. CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses. J. Immunol. 163:3194-3201.
    • (1999) J. Immunol. , vol.163 , pp. 3194-3201
    • Whitmire, J.K.1    Flavell, R.A.2    Grewal, I.S.3    Larsen, C.P.4    Pearson, T.C.5    Ahmed, R.6
  • 62
    • 33745224089 scopus 로고    scopus 로고
    • Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells
    • Williams, M.A., A.J. Tyznik, and M.J. Bevan. 2006. Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells. Nature. 441:890-893. http://dx.doi.org/10.1038/nature04790
    • (2006) Nature. , vol.441 , pp. 890-893
    • Williams, M.A.1    Tyznik, A.J.2    Bevan, M.J.3
  • 63
    • 51149108973 scopus 로고    scopus 로고
    • CD40Lexpressing CD8 T cells prime CD8alpha(+)DC for IL-12p70 production
    • Wong, K.L., F.C. Lew, P.A. MacAry, and D.M. Kemeny. 2008. CD40Lexpressing CD8 T cells prime CD8alpha(+)DC for IL-12p70 production. Eur. J. Immunol. 38:2251-2262. http://dx.doi.org/10.1002/eji.200838199
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2251-2262
    • Wong, K.L.1    Lew, F.C.2    MacAry, P.A.3    Kemeny, D.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.