Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8+T cell responses to influenza

Nature Immunology

Volumn 11, Issue 3, 2010, Pages 216-224

  Ballesteros Tato, André ^a   León, Beatriz ^a   Lund, Frances E ^a   Randall, Troy D ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; CD11B ANTIGEN; CD70 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OVALBUMIN; VIRUS NUCLEOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; CD8+ T LYMPHOCYTE; CELL MIGRATION; CONTROLLED STUDY; CROSS PRESENTATION; DENDRITIC CELL; IMMUNE RESPONSE; INFLUENZA; LUNG; LUNG ALVEOLUS MACROPHAGE; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; UPREGULATION;

ANIMALS; ANTIGENS, CD70; CD4-POSITIVE T-LYMPHOCYTES; CROSS-PRIMING; DENDRITIC CELLS; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNOPHENOTYPING; INFLUENZA A VIRUS; KINETICS; LYMPH NODES; MICE; MICE, INBRED BALB C; NUCLEOCAPSID PROTEINS; ORTHOMYXOVIRIDAE INFECTIONS;

EID: 76949094170     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1838     Document Type: Article

References (43)

1. + T cells by exogenous cell-associated antigens. Immunity 17, 211-220 (2002).
2. Heath, W.R. et al. Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunol. Rev. 199, 9-26 (2004).
3. Villadangos, J.A. & Schnorrer, P. Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo. Nat. Rev. Immunol. 7, 543-555 (2007).
4. Palm, N.W. & Medzhitov, R. Pattern recognition receptors and control of adaptive immunity. Immunol. Rev. 227, 221-233 (2009).
5. Hendriks, J. et al. CD27 is required for generation and long-term maintenance of T cell immunity. Nat. Immunol. 1, 433-440 (2000).
6. + T cell tolerance and permits effective immunity. Immunity 29, 934-946 (2008).
7. + T cells. J. Immunol. 180, 2912-2921 (2008).
8. + T-cell immunity by immature dendritic cells in a vaccination setting. Blood 113, 5167-5175 (2009).
9. Nakano, H. et al. Blood-derived infammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses. Nat. Immunol. 10, 394-402 (2009).
10. Leon, B., Lopez-Bravo, M. & Ardavin, C. Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania. Immunity 26, 519-531 (2007).
11. Sung, S.S. et al. A major lung CD103 (αE)-β7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins. J. Immunol. 176, 2161-2172 (2006).
12. GeurtsvanKessel, C.H. & Lambrecht, B.N. Division of labor between dendritic cell subsets of the lung. Mucosal Immunol 1, 442-450 (2008).
13. Hammad, H. & Lambrecht, B.N. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat. Rev. Immunol. 8, 193-204 (2008). (Pubitemid 351323293)
14. + T cell responses. PLoS One 4, e4204 (2009).
15. Brimnes, M.K., Bonifaz, L., Steinman, R.M. & Moran, T.M. Infuenza virus-induced dendritic cell maturation is associated with the induction of strong T cell immunity to a coadministered, normally nonimmunogenic protein. J. Exp. Med. 198, 133-144 (2003).
16. Belz, G.T. et al. Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus. Proc. Natl. Acad. Sci. USA 101, 8670-8675 (2004).
17. + dendritic cells. Nat. Immunol. 10, 488-495 (2009).
18. Lukens, M.V., Kruijsen, D., Coenjaerts, F.E., Kimpen, J.L. & van Bleek, G.M. Respiratory syncytial virus-induced activation and migration of respiratory dendritic cells and subsequent antigen presentation in the lung-draining lymph node. J. Virol. 83, 7235-7243 (2009).
19. Vyas, J.M., Van der Veen, A.G. & Ploegh, H.L. The known unknowns of antigen processing and presentation. Nat. Rev. Immunol. 8, 607-618 (2008).
20. + dendritic cells are generally involved in priming CTL immunity to viruses. J. Immunol. 172, 1996-2000 (2004).
21. + T cells. Nat. Immunol. 8, 1060-1066 (2007).
22. - dendritic cells cross-prime cytotoxic T cells in vivo. J. Exp. Med. 192, 1685-1696 (2000).
23. Lopez-Bravo, M. & Ardavin, C. In vivo induction of immune responses to pathogens by conventional dendritic cells. Immunity 29, 343-351 (2008).
24. Allan, R.S. et al. Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for effcient CTL priming. Immunity 25, 153-162 (2006).
25. Carbone, F.R., Belz, G.T. & Heath, W.R. Transfer of antigen between migrating and lymph node-resident DCs in peripheral T-cell tolerance and immunity. Trends Immunol. 25, 655-658 (2004).
26. + T cell crosspriming in vivo. Immunity 24, 191-201 (2006).
27. Vermaelen, K.Y., Carro-Muino, I., Lambrecht, B.N. & Pauwels, R.A. Specifc migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J. Exp. Med. 193, 51-60 (2001).
28. Vermaelen, K. & Pauwels, R. Accurate and simple discrimination of mouse pulmonary dendritic cell and macrophage populations by fow cytometry: methodology and new insights. Cytometry A 61, 170-177 (2004).
29. Nolte, M.A., van Olffen, R.W., van Gisbergen, K.P. & van Lier, R.A. Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology. Immunol. Rev. 229, 216-231 (2009).
30. Legge, K.L. & Braciale, T.J. Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection. Immunity 18, 265-277 (2003).
31. - pulmonary dendritic cell populations. J. Immunol. 180, 3019-3027 (2008).
32. + monocyte-derived dendritic cells and exudate macrophages produce infuenza-induced pulmonary immune pathology and mortality. J. Immunol. 180, 2562-2572 (2008).
33. Masten, B.J., Olson, G.K., Kusewitt, D.F. & Lipscomb, M.F. Flt3 ligand preferentially increases the number of functionally active myeloid dendritic cells in the lungs of mice. J. Immunol. 172, 4077-4083 (2004).
34. Iliev, I.D., Mileti, E., Matteoli, G., Chieppa, M. & Rescigno, M. Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning. Mucosal Immunol 2, 340-350 (2009).
35. Iliev, I.D. et al. Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells. Gut 58, 1481-1489 (2009).
36. Hao, X., Kim, T.S. & Braciale, T.J. Differential response of respiratory dendritic cell subsets to infuenza virus infection. J. Virol. 82, 4908-4919 (2008).
37. + T cells. J. Immunol. 178, 6861-6866 (2007).
38. + dendritic cells selectively present MHC class I-restricted noncytolytic viral and intracellular bacterial antigens in vivo. J. Immunol. 175, 196-200 (2005).
39. Di Pucchio, T. et al. Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nat. Immunol. 9, 551-557 (2008).
40. Mouries, J. et al. Plasmacytoid dendritic cells effciently cross-prime naive T cells in vivo after TLR activation. Blood 112, 3713-3722 (2008).
41. + T cells and subsequently express CD8α and CD205 molecules. J. Exp. Med. 195, 1233-1245 (2002).
42. - dendritic cells in vivo. J. Exp. Med. 196, 817-827 (2002).
43. Chung, Y. et al. Anatomic location defnes antigen presentation by dendritic cells to T cells in response to intravenous soluble antigens. Eur. J. Immunol. 37, 1453-1462 (2007).