메뉴 건너뛰기




Volumn 22, Issue 19, 2013, Pages 3960-3975

Deletion of tumor necrosis factor-α ameliorates neurodegeneration in sandhoff disease mice

Author keywords

[No Author keywords available]

Indexed keywords

GANGLIOSIDE; JANUS KINASE 2; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84884240246     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt250     Document Type: Article
Times cited : (42)

References (55)
  • 1
    • 33646195657 scopus 로고    scopus 로고
    • Cell and gene-based therapies for the lysosomal storage diseases
    • Hodges, B.L. and Cheng, S.H. (2006) Cell and gene-based therapies for the lysosomal storage diseases. Curr. Gene Ther., 6, 227-241.
    • (2006) Curr. Gene Ther. , vol.6 , pp. 227-241
    • Hodges, B.L.1    Cheng, S.H.2
  • 2
    • 33845343984 scopus 로고    scopus 로고
    • Sphingolipid metabolism diseases
    • Kolter, T. and Sandhoff, K. (2006) Sphingolipid metabolism diseases. Biochim. Biophys. Acta, 1758, 2057-2079.
    • (2006) Biochim. Biophys. Acta , vol.1758 , pp. 2057-2079
    • Kolter, T.1    Sandhoff, K.2
  • 3
    • 0025924830 scopus 로고
    • The human GM2 activator protein. A substrate specific cofactor of beta-hexosaminidase a
    • Meier, E.M., Schwarzmann, G., Furst, W. and Sandhoff, K. (1991) The human GM2 activator protein. A substrate specific cofactor of beta-hexosaminidase a. J. Biol. Chem., 266, 1879-1887.
    • (1991) J. Biol. Chem. , vol.266 , pp. 1879-1887
    • Meier, E.M.1    Schwarzmann, G.2    Furst, W.3    Sandhoff, K.4
  • 4
    • 0020642981 scopus 로고
    • Ganglioside GM2 N-acetyl-beta-D-galactosaminidase activity in cultured fibroblasts of late-infantile and adult GM2 gangliosidosis patients and of healthy probands with low hexosaminidase level
    • Conzelmann, E., Kytzia, H.J., Navon, R. and Sandhoff, K. (1983) Ganglioside GM2 N-acetyl-beta-D-galactosaminidase activity in cultured fibroblasts of late-infantile and adult GM2 gangliosidosis patients and of healthy probands with low hexosaminidase level. Am. J. Hum. Genet., 35, 900-913.
    • (1983) Am. J. Hum. Genet. , vol.35 , pp. 900-913
    • Conzelmann, E.1    Kytzia, H.J.2    Navon, R.3    Sandhoff, K.4
  • 7
    • 10744226948 scopus 로고    scopus 로고
    • Late onset Tay-Sachs disease in mice with targeted disruption of the hexa gene: behavioral changes and pathology of the central nervous system
    • Miklyaeva, E.I., Dong, W., Bureau, A., Fattahie, R., Xu, Y., Su, M., Fick, G.H., Huang, J.Q., Igdoura, S., Hanai, N. and Gravel, R.A. (2004) Late onset Tay-Sachs disease in mice with targeted disruption of the hexa gene: behavioral changes and pathology of the central nervous system. Brain Res., 1001, 37-50.
    • (2004) Brain Res. , vol.1001 , pp. 37-50
    • Miklyaeva, E.I.1    Dong, W.2    Bureau, A.3    Fattahie, R.4    Xu, Y.5    Su, M.6    Fick, G.H.7    Huang, J.Q.8    Igdoura, S.9    Hanai, N.10    Gravel, R.A.11
  • 8
    • 2942563944 scopus 로고    scopus 로고
    • Deletion of macrophage-inflammatory protein 1 alpha retards neurodegeneration in Sandhoff disease mice
    • Wu, Y.P. and Proia, R.L. (2004) Deletion of macrophage-inflammatory protein 1 alpha retards neurodegeneration in Sandhoff disease mice. Proc. Natl Acad. Sci. USA, 101, 8425-8430.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 8425-8430
    • Wu, Y.P.1    Proia, R.L.2
  • 10
    • 33645107513 scopus 로고    scopus 로고
    • See no evil, hear no evil, do no evil: the lessons of immune privilege
    • Niederkorn, J.Y. (2006) See no evil, hear no evil, do no evil: the lessons of immune privilege. Nat. Immunol., 7, 354-359.
    • (2006) Nat. Immunol. , vol.7 , pp. 354-359
    • Niederkorn, J.Y.1
  • 12
    • 11444256801 scopus 로고    scopus 로고
    • Glia and their cytokines in progression of neurodegeneration
    • Mrak, R.E. and Griffin, W.S. (2005) Glia and their cytokines in progression of neurodegeneration. Neurobiol. Aging, 26, 349-354.
    • (2005) Neurobiol. Aging , vol.26 , pp. 349-354
    • Mrak, R.E.1    Griffin, W.S.2
  • 13
    • 0035693924 scopus 로고    scopus 로고
    • Inflammation, autotoxicity and Alzheimer's disease
    • Mcgeer, P.L. and Mcgeer, E.G. (2001) Inflammation, autotoxicity and Alzheimer's disease. Neurobiol. Aging, 22, 799-809.
    • (2001) Neurobiol. Aging , vol.22 , pp. 799-809
    • Mcgeer, P.L.1    Mcgeer, E.G.2
  • 14
    • 1942454250 scopus 로고    scopus 로고
    • Inflammation and neurodegeneration in Parkinson's disease
    • Mcgeer, P.L. and Mcgeer, E.G. (2004) Inflammation and neurodegeneration in Parkinson's disease. Parkinsonism. Relat. Disord., 10(Suppl. 1), S3-S7.
    • (2004) Parkinsonism. Relat. Disord. , vol.10 , Issue.SUPPL. 1
    • Mcgeer, P.L.1    Mcgeer, E.G.2
  • 15
    • 36749017492 scopus 로고    scopus 로고
    • Manipulation of microglial activation as a therapeutic strategy in Alzheimer's disease
    • Shie, F.S. and Woltjer, R.L. (2007) Manipulation of microglial activation as a therapeutic strategy in Alzheimer's disease. Curr. Med. Chem., 14, 2865-2871.
    • (2007) Curr. Med. Chem. , vol.14 , pp. 2865-2871
    • Shie, F.S.1    Woltjer, R.L.2
  • 16
    • 0030782030 scopus 로고    scopus 로고
    • Apoptotic cell death in mouse models of GM2 gangliosidosis and observations on human Tay-Sachs and Sandhoff diseases
    • Huang, J.Q., Trasler, J.M., Igdoura, S., Michaud, J., Hanal, N. and Gravel, R.A. (1997) Apoptotic cell death in mouse models of GM2 gangliosidosis and observations on human Tay-Sachs and Sandhoff diseases. Hum. Mol. Genet., 6, 1879-1885.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1879-1885
    • Huang, J.Q.1    Trasler, J.M.2    Igdoura, S.3    Michaud, J.4    Hanal, N.5    Gravel, R.A.6
  • 17
    • 48049096529 scopus 로고    scopus 로고
    • Sphingosine kinase 1/S1P receptor signaling axis controls glial proliferation in mice with Sandhoff disease
    • Wu, Y.P., Mizugishi, K., Bektas, M., Sandhoff, R. and Proia, R.L. (2008) Sphingosine kinase 1/S1P receptor signaling axis controls glial proliferation in mice with Sandhoff disease. Hum. Mol. Genet., 17, 2257-2264.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 2257-2264
    • Wu, Y.P.1    Mizugishi, K.2    Bektas, M.3    Sandhoff, R.4    Proia, R.L.5
  • 18
    • 0037093476 scopus 로고    scopus 로고
    • Molecular pathophysiology in Tay-Sachs and Sandhoff diseases as revealed by gene expression profiling
    • Myerowitz, R., Lawson, D., Mizukami, H., Mi, Y., Tifft, C.J. and Proia, R.L. (2002) Molecular pathophysiology in Tay-Sachs and Sandhoff diseases as revealed by gene expression profiling. Hum. Mol. Genet., 11, 1343-1350.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 1343-1350
    • Myerowitz, R.1    Lawson, D.2    Mizukami, H.3    Mi, Y.4    Tifft, C.J.5    Proia, R.L.6
  • 20
    • 0037203538 scopus 로고    scopus 로고
    • Nuclear Factor-kappaB activation: a question of life or death
    • Shishodia, S. and Aggarwal, B.B. (2002) Nuclear Factor-kappaB activation: a question of life or death. J. Biochem. Mol. Biol., 35, 28-40.
    • (2002) J. Biochem. Mol. Biol. , vol.35 , pp. 28-40
    • Shishodia, S.1    Aggarwal, B.B.2
  • 21
    • 0037044896 scopus 로고    scopus 로고
    • Signal transduction. Decoding NF-kappaB signaling
    • Ting, A.Y. and Endy, D. (2002) Signal transduction. Decoding NF-kappaB signaling. Science, 298, 1189-1190.
    • (2002) Science , vol.298 , pp. 1189-1190
    • Ting, A.Y.1    Endy, D.2
  • 23
  • 24
    • 34247610848 scopus 로고    scopus 로고
    • Neuroscience: the Brain's garbage men
    • Kettenmann, H. (2007) Neuroscience: the Brain's garbage men. Nature, 446, 987-989.
    • (2007) Nature , vol.446 , pp. 987-989
    • Kettenmann, H.1
  • 25
    • 0033913980 scopus 로고    scopus 로고
    • Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-kappaB, AP-1, and CREB activation in HEK293 cells
    • Hirota, K., Matsui, M., Murata, M., Takashima, Y., Cheng, F.S., Itoh, T., Fukuda, K. and Yodoi, J. (2000) Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-kappaB, AP-1, and CREB activation in HEK293 cells. Biochem. Biophys. Res. Commun., 274, 177-182.
    • (2000) Biochem. Biophys. Res. Commun. , vol.274 , pp. 177-182
    • Hirota, K.1    Matsui, M.2    Murata, M.3    Takashima, Y.4    Cheng, F.S.5    Itoh, T.6    Fukuda, K.7    Yodoi, J.8
  • 26
    • 78650920066 scopus 로고    scopus 로고
    • Non-canonical NF-kappaB signaling pathway
    • Sun, S.C. (2011) Non-canonical NF-kappaB signaling pathway. Cell Res., 21, 71-85.
    • (2011) Cell Res. , vol.21 , pp. 71-85
    • Sun, S.C.1
  • 28
    • 0036548875 scopus 로고    scopus 로고
    • Neurodegenerative and neuroprotective effects of tumor necrosis factor (TNF) in retinal ischemia: opposite roles of tnf receptor 1 and tnf receptor 2
    • Fontaine, V., Mohand-Said, S., Hanoteau, N., Fuchs, C., Pfizenmaier, K. and Eisel, U. (2002) Neurodegenerative and neuroprotective effects of tumor necrosis factor (TNF) in retinal ischemia: opposite roles of tnf receptor 1 and tnf receptor 2. J. Neurosci., 22, Rc216.
    • (2002) J. Neurosci. , vol.22
    • Fontaine, V.1    Mohand-Said, S.2    Hanoteau, N.3    Fuchs, C.4    Pfizenmaier, K.5    Eisel, U.6
  • 29
    • 20744455652 scopus 로고    scopus 로고
    • Increases in tumor necrosis factor-alpha following transient global cerebral ischemia do not contribute to neuron death in mouse hippocampus
    • Murakami, Y., Saito, K., Hara, A., Zhu, Y., Sudo, K., Niwa, M., Fujii, H., Wada, H., Ishiguro, H., Mori, H. and Seishima, M. (2005) Increases in tumor necrosis factor-alpha following transient global cerebral ischemia do not contribute to neuron death in mouse hippocampus. J. Neurochem., 93, 1616-1622.
    • (2005) J. Neurochem. , vol.93 , pp. 1616-1622
    • Murakami, Y.1    Saito, K.2    Hara, A.3    Zhu, Y.4    Sudo, K.5    Niwa, M.6    Fujii, H.7    Wada, H.8    Ishiguro, H.9    Mori, H.10    Seishima, M.11
  • 30
    • 0034718598 scopus 로고    scopus 로고
    • Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation
    • Wada, R., Tifft, C.J. and Proia, R.L. (2000) Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation. Proc. Natl Acad. Sci. USA, 97, 10954-10959.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 10954-10959
    • Wada, R.1    Tifft, C.J.2    Proia, R.L.3
  • 33
    • 0037022618 scopus 로고    scopus 로고
    • Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells
    • Teng, Y.D., Lavik, E.B., Qu, X., Park, K.I., Ourednik, J., Zurakowski, D., Langer, R. and Snyder, E.Y. (2002) Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc. Natl Acad. Sci. USA, 99, 3024-3029.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 3024-3029
    • Teng, Y.D.1    Lavik, E.B.2    Qu, X.3    Park, K.I.4    Ourednik, J.5    Zurakowski, D.6    Langer, R.7    Snyder, E.Y.8
  • 36
    • 0033006017 scopus 로고    scopus 로고
    • Sialidase-mediated depletion of GM2 ganglioside in Tay-Sachs neuroglia Cells
    • Igdoura, S.A., Mertineit, C., Trasler, J.M. and Gravel, R.A. (1999) Sialidase-mediated depletion of GM2 ganglioside in Tay-Sachs neuroglia Cells. Hum. Mol. Genet., 8, 1111-1116.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 1111-1116
    • Igdoura, S.A.1    Mertineit, C.2    Trasler, J.M.3    Gravel, R.A.4
  • 37
  • 38
    • 34248641996 scopus 로고    scopus 로고
    • Targeting bid to prevent programmed cell death in neurons
    • Culmsee, C. and Plesnila, N. (2006) Targeting bid to prevent programmed cell death in neurons. Biochem. Soc. Trans., 34, 1334-1340.
    • (2006) Biochem. Soc. Trans. , vol.34 , pp. 1334-1340
    • Culmsee, C.1    Plesnila, N.2
  • 42
    • 2942687937 scopus 로고    scopus 로고
    • The cell biology of lysosomal storage disorders
    • Futerman, A.H. and Van, M.G. (2004) The cell biology of lysosomal storage disorders. Nat. Rev. Mol. Cell Biol., 5, 554-565.
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 554-565
    • Futerman, A.H.1    Van, M.G.2
  • 44
    • 64449085191 scopus 로고    scopus 로고
    • Pathogenic cascades in lysosomal disease-why so complex?
    • Walkley, S.U. (2009) Pathogenic cascades in lysosomal disease-why so complex? J. Inherit. Metab. Dis., 32, 181-189.
    • (2009) J. Inherit. Metab. Dis. , vol.32 , pp. 181-189
    • Walkley, S.U.1
  • 45
    • 18944384555 scopus 로고    scopus 로고
    • Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats
    • Suzuki, S., Yamashita, T., Tanaka, K., Hattori, H., Sawamoto, K., Okano, H. and Suzuki, N. (2005) Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats. J. Cereb. Blood Flow Metab., 25, 685-693.
    • (2005) J. Cereb. Blood Flow Metab. , vol.25 , pp. 685-693
    • Suzuki, S.1    Yamashita, T.2    Tanaka, K.3    Hattori, H.4    Sawamoto, K.5    Okano, H.6    Suzuki, N.7
  • 46
    • 84870607968 scopus 로고    scopus 로고
    • Protective role of STAT3 in nmda and glutamate-induced neuronal death: negative regulatory effect of SOCS3
    • Park, K.W., Nozell, S.E. and Benveniste, E.N. (2012) Protective role of STAT3 in nmda and glutamate-induced neuronal death: negative regulatory effect of SOCS3. PLoS One, 7, E50874.
    • (2012) PLoS One , vol.7
    • Park, K.W.1    Nozell, S.E.2    Benveniste, E.N.3
  • 47
    • 0032521284 scopus 로고    scopus 로고
    • Induction of jak/stat signaling by activation of the type 1 TNF receptor
    • Guo, D., Dunbar, J.D., Yang, C.H., Pfeffer, L.M. and Donner, D.B. (1998) Induction of jak/stat signaling by activation of the type 1 TNF receptor. J. Immunol., 160, 2742-2750.
    • (1998) J. Immunol. , vol.160 , pp. 2742-2750
    • Guo, D.1    Dunbar, J.D.2    Yang, C.H.3    Pfeffer, L.M.4    Donner, D.B.5
  • 48
    • 49049106608 scopus 로고    scopus 로고
    • Type 1 TNF receptor forms a complex with and uses JAK2 and C-SRC to selectively engage signaling pathways that regulate transcription factor activity
    • Pincheira, R., Castro, A.F., Ozes, O.N., Idumalla, P.S. and Donner, D.B. (2008) Type 1 TNF receptor forms a complex with and uses JAK2 and C-SRC to selectively engage signaling pathways that regulate transcription factor activity. J. Immunol., 181, 1288-1298.
    • (2008) J. Immunol. , vol.181 , pp. 1288-1298
    • Pincheira, R.1    Castro, A.F.2    Ozes, O.N.3    Idumalla, P.S.4    Donner, D.B.5
  • 49
    • 63349094897 scopus 로고    scopus 로고
    • Alterations of the microrna network cause neurodegenerative disease
    • Hebert, S.S. and De, S.B. (2009) Alterations of the microrna network cause neurodegenerative disease. Trends Neurosci., 32, 199-206.
    • (2009) Trends Neurosci. , vol.32 , pp. 199-206
    • Hebert, S.S.1    De, S.B.2
  • 50
    • 56349164232 scopus 로고    scopus 로고
    • Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling
    • Vallabhapurapu, S., Matsuzawa, A., Zhang, W., Tseng, P.H., Keats, J.J., Wang, H., Vignali, D.A., Bergsagel, P.L. and Karin, M. (2008) Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat. Immunol., 9, 1364-1370.
    • (2008) Nat. Immunol. , vol.9 , pp. 1364-1370
    • Vallabhapurapu, S.1    Matsuzawa, A.2    Zhang, W.3    Tseng, P.H.4    Keats, J.J.5    Wang, H.6    Vignali, D.A.7    Bergsagel, P.L.8    Karin, M.9
  • 52
    • 0035168688 scopus 로고    scopus 로고
    • Enhanced survival in Sandhoff disease mice receiving a combination of substrate deprivation therapy and bone marrow transplantation
    • Jeyakumar, M., Norflus, F., Tifft, C.J., Cortina-Borja, M., Butters, T.D., Proia, R.L., Perry, V.H., Dwek, R.A. and Platt, F.M. (2001) Enhanced survival in Sandhoff disease mice receiving a combination of substrate deprivation therapy and bone marrow transplantation. Blood, 97, 327-329.
    • (2001) Blood , vol.97 , pp. 327-329
    • Jeyakumar, M.1    Norflus, F.2    Tifft, C.J.3    Cortina-Borja, M.4    Butters, T.D.5    Proia, R.L.6    Perry, V.H.7    Dwek, R.A.8    Platt, F.M.9
  • 53
    • 0014424692 scopus 로고
    • Comprehensive observational assessment: ia.Asystematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse
    • Irwin, S. (1968) Comprehensive observational assessment: ia.Asystematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. Psychopharmacologia, 13, 222-257.
    • (1968) Psychopharmacologia , vol.13 , pp. 222-257
    • Irwin, S.1
  • 54
    • 0027173341 scopus 로고
    • Utility of a neurobehavioral screening battery for differentiating the effects of two pyrethroids, permethrin and cypermethrin
    • Mcdaniel, K.L. and Moser, V.C. (1993) Utility of a neurobehavioral screening battery for differentiating the effects of two pyrethroids, permethrin and cypermethrin. Neurotoxicol. Teratol., 15, 71-83.
    • (1993) Neurotoxicol. Teratol. , vol.15 , pp. 71-83
    • Mcdaniel, K.L.1    Moser, V.C.2
  • 55
    • 0018385828 scopus 로고
    • A simple rapid method for ganglioside isolation from small amounts of tissue
    • Irwin, C.C. and Irwin, L.N. (1979) A simple rapid method for ganglioside isolation from small amounts of tissue. Anal. Biochem., 94, 335-339.
    • (1979) Anal. Biochem. , vol.94 , pp. 335-339
    • Irwin, C.C.1    Irwin, L.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.